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The map label for this gene is ychM [C]

Identifier: 154247178

GI number: 154247178

Start: 3605478

End: 3607187

Strand: Direct

Name: ychM [C]

Synonym: Xaut_3250

Alternate gene names: 154247178

Gene position: 3605478-3607187 (Clockwise)

Preceding gene: 154247176

Following gene: 154247179

Centisome position: 67.91

GC content: 70.23

Gene sequence:

>1710_bases
GTGCGTGAAGCCCTCAGGCGCTGGGCACCCGGGCTAGCTGCTCTCCTCGCCTATCGCCGGGCGGATCTCGGCCCCGACCT
GAGGGCGGGGCTGGCGGTGGCGGCGGTGGCGATCCCGGTGGGCATCGCCTATGCCGAGCTTGCCGGCTTCCGCCCGGAGG
TCGGCCTGTATTCCTGCGTCTTCCCCCTCGTCGCCTATGCCATCTTCGGTTCGTCCCGCCAGCTGGTGCTGGGGCCGGAT
GCGGCAACCTGTGCCGTCATCGCCTCGGCCGTGGCGCCGCTGGCGGCCGGAGACGGGGCGGCCTATGCGGCGCTGTCCGC
CGAGCTGGCCCTCCTCACCGGCATCATCTGCATCCTGGCGCGGTTTCTGCGCCTCGGCGTGCTGGCCGATTTCCTCTCCA
AGCCCATCCTCATCGGTTTCCTGAACGGCATCGCCATCACCATCGTGCTGGGCCAGCTTGCCAAGATCACGCGGATCGAG
GCGGAGGGCGACCACGTCCTGCATGCCACCTTCGATCTTGTCGTGCGCCTGGGCGAGACCCATCCGCCGACCCTGCTGAT
CGCGCTCGGTGCGTTCGGCCTCATGATCGCGAGCGGCCGGCTGCTGCCGGCCTTTCCGGCCGCGGTGCTGGCCATGGCCG
GCGCGGCGCTGGCGGTGTTCCTGCTGGGGCTCGACCTGTCCGGAGTGAAGACGTTGGGCGTGGTGCCGGCAGGGCTACCG
GGCGTGATGCTGGTCCGGCTCGATCCCGACGCGCTGGCCGCGCTCGTGCCCGCCGCCGGCGGCCTCGCCTTGGTGAGCTT
CACCAGCATGATGCTCACGTCCCGCTCCTTCGCCTCGAAGAACGGTTACGAGGTGGACCCGGACAAGGACTTCGCCGCCC
TCGGCGCCGCCAACGTGGTTTCGGCCCTCACCCACGGCTTCGCCGTCAGCGGGGCGGATTCACGGACCGCCATGGCGGAT
GCCGCCGGCGGGCGTACCCACGCCGCCGCCTTGGTCGCGGCCGTGGCGGTGGCGCTGGTGCTCATGTTCCTCACCGCGCC
CCTGCGCTACGTGCCGGTGGCGGCGCTGGGCGCGGTGCTGGTGATGGCGGGCCTCTCGCTGGTGGACCTTGCCACCCTGC
GCCTTATCGCCCGCGCCGACCGGACGGAGGCGGTGATCTCCCTTCTGGCCACGCTCGGGGTGGTGGTATTGGGGGCGACA
CAGGGCATCCTGGTCGCGGTGGTGCTGGCCCTGCTGCGGTTCCTGCACATCAGCGCACGGCCCCGGGTGGAAATCCTCGG
CCGGGTGGCGGGCATGCCGGGCTTCCATGCCCTGTCGCGGCACGAAAGCGCGACGGCGCCTCACGGCCTCGTCATCTTCC
GCTTCAACGGCCCGCTCGTCTTCTTCAACGCCGGTCATTTCCGCCACGCGCTGATGGCGGCCACCAGCGCCGAGCAGGGG
GCGCCGAAGGCTGTCATCCTCGATCTGCTGCCAGTGACGGAAGTGGACGTGACGGGCCTTTTTACCCTGAAGGAGGTGTC
CGATGCCCTGCGCCAGCGCGGCATCGCGCTGGTCGGCGCCGGGCGACAGACCGAGTGGCGCAACTGGATGGTCACCCACG
GCTTCAACCCCGATGGCATCGTCATGCACCCCACCCTGCGTCACGCCGTGAAGGCGCTCGCAGCGGCGGATACGGACCAT
GCCGATGCGGATGATACGAAGGTGTCATAA

Upstream 100 bases:

>100_bases
GCTATGAGCCTCAACCATCCTCGTCTAAAATCTTGGCGTGCGTGTCCGCCGCAAATCCCGACGGTCTGCGCGGTGACGCG
GCAAGGCGAGGAGCGGGATC

Downstream 100 bases:

>100_bases
ATCCAAGGATTGATTTGTGTCATGGAAGACGAGAGCCTGAATTCGGCATAGGCTTGGGGACGCATTCGGCTTGAGCCCAC
CTCGGTAGAGGCTATTTTTT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MREALRRWAPGLAALLAYRRADLGPDLRAGLAVAAVAIPVGIAYAELAGFRPEVGLYSCVFPLVAYAIFGSSRQLVLGPD
AATCAVIASAVAPLAAGDGAAYAALSAELALLTGIICILARFLRLGVLADFLSKPILIGFLNGIAITIVLGQLAKITRIE
AEGDHVLHATFDLVVRLGETHPPTLLIALGAFGLMIASGRLLPAFPAAVLAMAGAALAVFLLGLDLSGVKTLGVVPAGLP
GVMLVRLDPDALAALVPAAGGLALVSFTSMMLTSRSFASKNGYEVDPDKDFAALGAANVVSALTHGFAVSGADSRTAMAD
AAGGRTHAAALVAAVAVALVLMFLTAPLRYVPVAALGAVLVMAGLSLVDLATLRLIARADRTEAVISLLATLGVVVLGAT
QGILVAVVLALLRFLHISARPRVEILGRVAGMPGFHALSRHESATAPHGLVIFRFNGPLVFFNAGHFRHALMAATSAEQG
APKAVILDLLPVTEVDVTGLFTLKEVSDALRQRGIALVGAGRQTEWRNWMVTHGFNPDGIVMHPTLRHAVKALAAADTDH
ADADDTKVS

Sequences:

>Translated_569_residues
MREALRRWAPGLAALLAYRRADLGPDLRAGLAVAAVAIPVGIAYAELAGFRPEVGLYSCVFPLVAYAIFGSSRQLVLGPD
AATCAVIASAVAPLAAGDGAAYAALSAELALLTGIICILARFLRLGVLADFLSKPILIGFLNGIAITIVLGQLAKITRIE
AEGDHVLHATFDLVVRLGETHPPTLLIALGAFGLMIASGRLLPAFPAAVLAMAGAALAVFLLGLDLSGVKTLGVVPAGLP
GVMLVRLDPDALAALVPAAGGLALVSFTSMMLTSRSFASKNGYEVDPDKDFAALGAANVVSALTHGFAVSGADSRTAMAD
AAGGRTHAAALVAAVAVALVLMFLTAPLRYVPVAALGAVLVMAGLSLVDLATLRLIARADRTEAVISLLATLGVVVLGAT
QGILVAVVLALLRFLHISARPRVEILGRVAGMPGFHALSRHESATAPHGLVIFRFNGPLVFFNAGHFRHALMAATSAEQG
APKAVILDLLPVTEVDVTGLFTLKEVSDALRQRGIALVGAGRQTEWRNWMVTHGFNPDGIVMHPTLRHAVKALAAADTDH
ADADDTKVS
>Mature_569_residues
MREALRRWAPGLAALLAYRRADLGPDLRAGLAVAAVAIPVGIAYAELAGFRPEVGLYSCVFPLVAYAIFGSSRQLVLGPD
AATCAVIASAVAPLAAGDGAAYAALSAELALLTGIICILARFLRLGVLADFLSKPILIGFLNGIAITIVLGQLAKITRIE
AEGDHVLHATFDLVVRLGETHPPTLLIALGAFGLMIASGRLLPAFPAAVLAMAGAALAVFLLGLDLSGVKTLGVVPAGLP
GVMLVRLDPDALAALVPAAGGLALVSFTSMMLTSRSFASKNGYEVDPDKDFAALGAANVVSALTHGFAVSGADSRTAMAD
AAGGRTHAAALVAAVAVALVLMFLTAPLRYVPVAALGAVLVMAGLSLVDLATLRLIARADRTEAVISLLATLGVVVLGAT
QGILVAVVLALLRFLHISARPRVEILGRVAGMPGFHALSRHESATAPHGLVIFRFNGPLVFFNAGHFRHALMAATSAEQG
APKAVILDLLPVTEVDVTGLFTLKEVSDALRQRGIALVGAGRQTEWRNWMVTHGFNPDGIVMHPTLRHAVKALAAADTDH
ADADDTKVS

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=560, Percent_Identity=28.2142857142857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI262206075, Length=560, Percent_Identity=28.2142857142857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI262206069, Length=560, Percent_Identity=28.2142857142857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI262206063, Length=560, Percent_Identity=28.2142857142857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI39752683, Length=520, Percent_Identity=25.1923076923077, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI45827800, Length=520, Percent_Identity=25.1923076923077, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI94721253, Length=465, Percent_Identity=25.8064516129032, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721257, Length=465, Percent_Identity=25.8064516129032, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721255, Length=465, Percent_Identity=25.8064516129032, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721259, Length=465, Percent_Identity=25.8064516129032, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4557535, Length=508, Percent_Identity=25.5905511811024, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI269784651, Length=518, Percent_Identity=24.5173745173745, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI45827802, Length=461, Percent_Identity=25.1626898047722, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI4505697, Length=506, Percent_Identity=23.7154150197628, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI16418413, Length=514, Percent_Identity=25.4863813229572, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI217272867, Length=514, Percent_Identity=25.4863813229572, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI100913030, Length=523, Percent_Identity=25.6214149139579, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI47131207, Length=526, Percent_Identity=26.0456273764259, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI20336272, Length=526, Percent_Identity=26.0456273764259, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI20336282, Length=510, Percent_Identity=24.1176470588235, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI16306483, Length=510, Percent_Identity=24.1176470588235, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI16418457, Length=533, Percent_Identity=24.390243902439, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI301601599, Length=533, Percent_Identity=24.390243902439, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI65506789, Length=378, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI301601602, Length=230, Percent_Identity=24.7826086956522, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI45827804, Length=274, Percent_Identity=23.3576642335766, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081859, Length=431, Percent_Identity=25.9860788863109, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551690, Length=612, Percent_Identity=23.5294117647059, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17562578, Length=630, Percent_Identity=24.2857142857143, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86564196, Length=626, Percent_Identity=23.1629392971246, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17566848, Length=559, Percent_Identity=25.7602862254025, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI86565215, Length=573, Percent_Identity=25.3054101221641, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193203292, Length=504, Percent_Identity=22.6190476190476, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI86564876, Length=378, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI86565213, Length=165, Percent_Identity=28.4848484848485, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319771, Length=470, Percent_Identity=26.8085106382979, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6323121, Length=462, Percent_Identity=26.4069264069264, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325260, Length=572, Percent_Identity=22.2027972027972, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24666186, Length=640, Percent_Identity=25.15625, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24651449, Length=622, Percent_Identity=25.5627009646302, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24649801, Length=559, Percent_Identity=25.4025044722719, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21358229, Length=478, Percent_Identity=26.5690376569038, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19922482, Length=520, Percent_Identity=24.0384615384615, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI85815873, Length=447, Percent_Identity=27.5167785234899, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24663084, Length=153, Percent_Identity=38.562091503268, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357695, Length=153, Percent_Identity=38.562091503268, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21358633, Length=141, Percent_Identity=28.3687943262411, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 58639; Mature: 58639

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREALRRWAPGLAALLAYRRADLGPDLRAGLAVAAVAIPVGIAYAELAGFRPEVGLYSCV
CHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FPLVAYAIFGSSRQLVLGPDAATCAVIASAVAPLAAGDGAAYAALSAELALLTGIICILA
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
RFLRLGVLADFLSKPILIGFLNGIAITIVLGQLAKITRIEAEGDHVLHATFDLVVRLGET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHCCC
HPPTLLIALGAFGLMIASGRLLPAFPAAVLAMAGAALAVFLLGLDLSGVKTLGVVPAGLP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCC
GVMLVRLDPDALAALVPAAGGLALVSFTSMMLTSRSFASKNGYEVDPDKDFAALGAANVV
CEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
SALTHGFAVSGADSRTAMADAAGGRTHAAALVAAVAVALVLMFLTAPLRYVPVAALGAVL
HHHHHCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VMAGLSLVDLATLRLIARADRTEAVISLLATLGVVVLGATQGILVAVVLALLRFLHISAR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
PRVEILGRVAGMPGFHALSRHESATAPHGLVIFRFNGPLVFFNAGHFRHALMAATSAEQG
CHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCC
APKAVILDLLPVTEVDVTGLFTLKEVSDALRQRGIALVGAGRQTEWRNWMVTHGFNPDGI
CCCEEEEEECCCCCCCCCHHEHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCE
VMHPTLRHAVKALAAADTDHADADDTKVS
EECHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MREALRRWAPGLAALLAYRRADLGPDLRAGLAVAAVAIPVGIAYAELAGFRPEVGLYSCV
CHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FPLVAYAIFGSSRQLVLGPDAATCAVIASAVAPLAAGDGAAYAALSAELALLTGIICILA
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
RFLRLGVLADFLSKPILIGFLNGIAITIVLGQLAKITRIEAEGDHVLHATFDLVVRLGET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHCCC
HPPTLLIALGAFGLMIASGRLLPAFPAAVLAMAGAALAVFLLGLDLSGVKTLGVVPAGLP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCC
GVMLVRLDPDALAALVPAAGGLALVSFTSMMLTSRSFASKNGYEVDPDKDFAALGAANVV
CEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
SALTHGFAVSGADSRTAMADAAGGRTHAAALVAAVAVALVLMFLTAPLRYVPVAALGAVL
HHHHHCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VMAGLSLVDLATLRLIARADRTEAVISLLATLGVVVLGATQGILVAVVLALLRFLHISAR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
PRVEILGRVAGMPGFHALSRHESATAPHGLVIFRFNGPLVFFNAGHFRHALMAATSAEQG
CHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCC
APKAVILDLLPVTEVDVTGLFTLKEVSDALRQRGIALVGAGRQTEWRNWMVTHGFNPDGI
CCCEEEEEECCCCCCCCCHHEHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCE
VMHPTLRHAVKALAAADTDHADADDTKVS
EECHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]