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The map label for this gene is murA

Identifier: 154247060

GI number: 154247060

Start: 3472747

End: 3474036

Strand: Reverse

Name: murA

Synonym: Xaut_3131

Alternate gene names: 154247060

Gene position: 3474036-3472747 (Counterclockwise)

Preceding gene: 154247067

Following gene: 154247059

Centisome position: 65.44

GC content: 68.91

Gene sequence:

>1290_bases
ATGGACAAGATTCGCATCGTCGGCGGAAACGAGCTCAAGGGCACCATTCCCATTTCCGGTGCGAAGAATGCAGCCCTGCC
GCTGATGATCGCCAGCCTCCTGACCGAGGAGAAGCTGATTCTCGAGAACGTGCCGCGCCTCGCGGACGTGGCGCTGCTGC
AGCGCATCCTCGGCAATCACGGCGTGGACATCACCACCAACGGCAAGCGCAACGGCGACGATCCCTATGCCGGCCAGACG
CTGGAGATCGACGCGCGGGTGATCGTGGACACCACGGCGCCCTATGACCTCGTCTCGCGCATGCGCGCCTCGTTCTGGGT
GCTGGGGCCGCTCCTGGCCCGCATCGGCGTGGCCAAGGTGTCGCTGCCCGGCGGCTGCGCCATCGGCACCCGACCGGTGG
ATTTCCATCTCGATGCCCTGCGCGCCCTCGGCGCCGAGATCGAGATCGATGCCGGCTATGTGGTGGCGAAGGCGCCCCAG
GGCCTCAAGGGCGCGCGCATCGTGTTCCCCAAGGTGTCCGTGGGCGCCACCCACACTGCCCTGATGGCCGCCACCCTCGC
CCGCGGCGACAGCATCATCGAGAATGCCGCCCGCGAGCCGGAGGTGGTGGATCTCGCCGACTGCCTCATCAAGATGGGCG
CCCGCATTACCGGTGCCGGCAGTTCCACCATCCATGTGGAGGGCGTGGCCCGCCTGAAGGCCGCCCGCCACGCGGTGCTG
CCTGACCGCATCGAGACCGGCACCTATGCCATGGCCACCGCCATGACCGGCGGCGACGTGATGCTCGCCGGCGCCCGGCC
CGACCTGCTGGAAAGCGCGCTGGACGCCCTGCGCCAGGCCGGCGCCGAGATCGACGCCACCAACGAGGGCATCCGGGTGC
GCCGCAACGGCGCCGGCATCCTGCCGGTGGACGTGACCACCGCCCCCTACCCCGGCTTCCCCACCGATCTCCAGGCCCAG
TTCATGGCGCTCATGACCAAGGCCAAGGGCAATTGCCGCATCACCGAGACCATTTTCGAGAACCGCTTCATGCATGTGCA
GGAGCTGGCCCGGCTCGGCGCCCGCATCCATCTCGATGGCGACACCGCCGTGGTGGAGGGGGTGGAGCGACTGACCGGCG
CGCCGGTGATGGCCACCGATCTTCGCGCCTCGGTCTCCCTGGTCATCGCCGGCCTCGCGGCGGAGGGCGAAACCATGGTC
CAGCGCGTCTACCACCTCGACCGCGGCTTCGAGAAGCTGGAGGAGAAGCTGTCGCGGTGCGGCGCGCAGATCGAGCGCAT
CAGCGGATGA

Upstream 100 bases:

>100_bases
CAAGATTGTGCCGGACGGCGAGCCGGGCTAGAGCTTTTCCCTTGAATTTGATGGTCGGCCGGCTTTGGGGGGGCCAGCCG
GCAGGAGGCACAGGTAGCGC

Downstream 100 bases:

>100_bases
TCCGGGGCGTGGACAGCGCCTAACATCAAGACAGGGAACGCGATATCCGGCCGGCTTGCGATCGAGGCGGCCGGCATCCT
CCCGGCGGCGCGGAGGACGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDKIRIVGGNELKGTIPISGAKNAALPLMIASLLTEEKLILENVPRLADVALLQRILGNHGVDITTNGKRNGDDPYAGQT
LEIDARVIVDTTAPYDLVSRMRASFWVLGPLLARIGVAKVSLPGGCAIGTRPVDFHLDALRALGAEIEIDAGYVVAKAPQ
GLKGARIVFPKVSVGATHTALMAATLARGDSIIENAAREPEVVDLADCLIKMGARITGAGSSTIHVEGVARLKAARHAVL
PDRIETGTYAMATAMTGGDVMLAGARPDLLESALDALRQAGAEIDATNEGIRVRRNGAGILPVDVTTAPYPGFPTDLQAQ
FMALMTKAKGNCRITETIFENRFMHVQELARLGARIHLDGDTAVVEGVERLTGAPVMATDLRASVSLVIAGLAAEGETMV
QRVYHLDRGFEKLEEKLSRCGAQIERISG

Sequences:

>Translated_429_residues
MDKIRIVGGNELKGTIPISGAKNAALPLMIASLLTEEKLILENVPRLADVALLQRILGNHGVDITTNGKRNGDDPYAGQT
LEIDARVIVDTTAPYDLVSRMRASFWVLGPLLARIGVAKVSLPGGCAIGTRPVDFHLDALRALGAEIEIDAGYVVAKAPQ
GLKGARIVFPKVSVGATHTALMAATLARGDSIIENAAREPEVVDLADCLIKMGARITGAGSSTIHVEGVARLKAARHAVL
PDRIETGTYAMATAMTGGDVMLAGARPDLLESALDALRQAGAEIDATNEGIRVRRNGAGILPVDVTTAPYPGFPTDLQAQ
FMALMTKAKGNCRITETIFENRFMHVQELARLGARIHLDGDTAVVEGVERLTGAPVMATDLRASVSLVIAGLAAEGETMV
QRVYHLDRGFEKLEEKLSRCGAQIERISG
>Mature_429_residues
MDKIRIVGGNELKGTIPISGAKNAALPLMIASLLTEEKLILENVPRLADVALLQRILGNHGVDITTNGKRNGDDPYAGQT
LEIDARVIVDTTAPYDLVSRMRASFWVLGPLLARIGVAKVSLPGGCAIGTRPVDFHLDALRALGAEIEIDAGYVVAKAPQ
GLKGARIVFPKVSVGATHTALMAATLARGDSIIENAAREPEVVDLADCLIKMGARITGAGSSTIHVEGVARLKAARHAVL
PDRIETGTYAMATAMTGGDVMLAGARPDLLESALDALRQAGAEIDATNEGIRVRRNGAGILPVDVTTAPYPGFPTDLQAQ
FMALMTKAKGNCRITETIFENRFMHVQELARLGARIHLDGDTAVVEGVERLTGAPVMATDLRASVSLVIAGLAAEGETMV
QRVYHLDRGFEKLEEKLSRCGAQIERISG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=52.4475524475524, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_XANP2 (A7IK18)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418018.1
- ProteinModelPortal:   A7IK18
- SMR:   A7IK18
- STRING:   A7IK18
- GeneID:   5423933
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3131
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   XAUT78245:XAUT_3131-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45442; Mature: 45442

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIRIVGGNELKGTIPISGAKNAALPLMIASLLTEEKLILENVPRLADVALLQRILGNH
CCCEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
GVDITTNGKRNGDDPYAGQTLEIDARVIVDTTAPYDLVSRMRASFWVLGPLLARIGVAKV
CEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEE
SLPGGCAIGTRPVDFHLDALRALGAEIEIDAGYVVAKAPQGLKGARIVFPKVSVGATHTA
ECCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCEEEEECCCCCCHHHH
LMAATLARGDSIIENAAREPEVVDLADCLIKMGARITGAGSSTIHVEGVARLKAARHAVL
HHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEHHHHHHHHHHHHCC
PDRIETGTYAMATAMTGGDVMLAGARPDLLESALDALRQAGAEIDATNEGIRVRRNGAGI
CCCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEE
LPVDVTTAPYPGFPTDLQAQFMALMTKAKGNCRITETIFENRFMHVQELARLGARIHLDG
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECC
DTAVVEGVERLTGAPVMATDLRASVSLVIAGLAAEGETMVQRVYHLDRGFEKLEEKLSRC
CHHHHHHHHHHCCCCEEEHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAQIERISG
HHHHHHCCC
>Mature Secondary Structure
MDKIRIVGGNELKGTIPISGAKNAALPLMIASLLTEEKLILENVPRLADVALLQRILGNH
CCCEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
GVDITTNGKRNGDDPYAGQTLEIDARVIVDTTAPYDLVSRMRASFWVLGPLLARIGVAKV
CEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEE
SLPGGCAIGTRPVDFHLDALRALGAEIEIDAGYVVAKAPQGLKGARIVFPKVSVGATHTA
ECCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCEEEEECCCCCCHHHH
LMAATLARGDSIIENAAREPEVVDLADCLIKMGARITGAGSSTIHVEGVARLKAARHAVL
HHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEHHHHHHHHHHHHCC
PDRIETGTYAMATAMTGGDVMLAGARPDLLESALDALRQAGAEIDATNEGIRVRRNGAGI
CCCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEE
LPVDVTTAPYPGFPTDLQAQFMALMTKAKGNCRITETIFENRFMHVQELARLGARIHLDG
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECC
DTAVVEGVERLTGAPVMATDLRASVSLVIAGLAAEGETMVQRVYHLDRGFEKLEEKLSRC
CHHHHHHHHHHCCCCEEEHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAQIERISG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA