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The map label for this gene is fabD [H]

Identifier: 154247045

GI number: 154247045

Start: 3456764

End: 3457750

Strand: Reverse

Name: fabD [H]

Synonym: Xaut_3116

Alternate gene names: 154247045

Gene position: 3457750-3456764 (Counterclockwise)

Preceding gene: 154247053

Following gene: 154247044

Centisome position: 65.13

GC content: 71.53

Gene sequence:

>987_bases
ATGTCGGATGGGCCGCGTACAGGATCTCAGACCGCCTTTATCTTCCCCGGCCAGGGCAGCCAGGCCGTGGGAATGGGCAA
GGCGCTGGCGGACAATTTCCCGGCCGCCAAGGCCGTGTTCGATGAAGTGGACGCCGCCCTCAACGAGAGCCTGACGCAGG
TGATGTGGGATGGCCCCATCGACGCGCTGACCCTCACCGCCAATGCCCAGCCGGCGCTCATGGCGGTCTCCCTCGCCGCC
CTGCGCGTGCTGGAGACCGAGGCGGGGCTCGACCTTGCCCGCGAGGCCGCCTTCGTGGCCGGCCATTCGCTGGGCGAATA
TTCCGCCCTCGCCGCCGCCGGCGCCCTCACCATCACCGAGGCCGCCCGGCTGCTGCGCATCCGCGGCCGCGCCATGCAGG
AGGCGGTTCCCGTGGGCGAAGGCGCCATGGCGGCGCTCCTTGGCCTCGACTACGACCAGGCCGTGGCGGTGGCGGCGGAA
GCCGCCGGCGACGACGTGTGCGAAGCGGCCAACGACAACGCCCCCGGCCAGGTGGTGGTCTCCGGCACCAAGGCGGCGGT
AGAACGCGCGATTGTCATCGCCAAGGAGAAGGGCGCCATGAAGGCCCTGCTCCTGCCGGTGTCCGCCCCCTTCCATTGCC
GCCTCATGGGCCCCGCCGCCGAGGCCATGGAAGTGGCGCTCTCCGGCTCCACCGTCATGACCCCGCGGGTGCCGCTGGTG
GCTAATGTGCGCGCCTCCCCGGTCACCGACCCGGCCGAGATCGTCCGCCTGCTAGTGGAGCAGGTGACCGGCACGGTGCG
CTGGCGCGAAAGCGTCATCTACATGGCGGGCGCGGGCGTGACGCGCATGGTTGAGGTCGGCGCCGGCAAGGTGCTGTGCG
GCCTCGTGAAGCGCATCGACAAGTCGGTGTCCGCCAGCGCCGTGGGCACGCCGGAAGACGTGGCGGCCTTCATCGCCGCC
CGCAACGCCGCTGCCTCGGCGGCCTGA

Upstream 100 bases:

>100_bases
CAAACGCCTGCGCTTCCGCAAAGTCAAGTTCCCTCGCCTTGACTCGCCCACATTCCGGGTGTCTCTGCCCTCCCCAAATT
TGATAACCGGAGGGCCGCGC

Downstream 100 bases:

>100_bases
GGCGCGATTTTCCAGACCTGAAGCCCTCTTCCGCGCAGAAGCCGGATATATCCGGCTTCTGCCCTTACGAACCGAACGCG
GCAACAGCCGCGTTCGGGCC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSDGPRTGSQTAFIFPGQGSQAVGMGKALADNFPAAKAVFDEVDAALNESLTQVMWDGPIDALTLTANAQPALMAVSLAA
LRVLETEAGLDLAREAAFVAGHSLGEYSALAAAGALTITEAARLLRIRGRAMQEAVPVGEGAMAALLGLDYDQAVAVAAE
AAGDDVCEAANDNAPGQVVVSGTKAAVERAIVIAKEKGAMKALLLPVSAPFHCRLMGPAAEAMEVALSGSTVMTPRVPLV
ANVRASPVTDPAEIVRLLVEQVTGTVRWRESVIYMAGAGVTRMVEVGAGKVLCGLVKRIDKSVSASAVGTPEDVAAFIAA
RNAAASAA

Sequences:

>Translated_328_residues
MSDGPRTGSQTAFIFPGQGSQAVGMGKALADNFPAAKAVFDEVDAALNESLTQVMWDGPIDALTLTANAQPALMAVSLAA
LRVLETEAGLDLAREAAFVAGHSLGEYSALAAAGALTITEAARLLRIRGRAMQEAVPVGEGAMAALLGLDYDQAVAVAAE
AAGDDVCEAANDNAPGQVVVSGTKAAVERAIVIAKEKGAMKALLLPVSAPFHCRLMGPAAEAMEVALSGSTVMTPRVPLV
ANVRASPVTDPAEIVRLLVEQVTGTVRWRESVIYMAGAGVTRMVEVGAGKVLCGLVKRIDKSVSASAVGTPEDVAAFIAA
RNAAASAA
>Mature_327_residues
SDGPRTGSQTAFIFPGQGSQAVGMGKALADNFPAAKAVFDEVDAALNESLTQVMWDGPIDALTLTANAQPALMAVSLAAL
RVLETEAGLDLAREAAFVAGHSLGEYSALAAAGALTITEAARLLRIRGRAMQEAVPVGEGAMAALLGLDYDQAVAVAAEA
AGDDVCEAANDNAPGQVVVSGTKAAVERAIVIAKEKGAMKALLLPVSAPFHCRLMGPAAEAMEVALSGSTVMTPRVPLVA
NVRASPVTDPAEIVRLLVEQVTGTVRWRESVIYMAGAGVTRMVEVGAGKVLCGLVKRIDKSVSASAVGTPEDVAAFIAAR
NAAASAA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=314, Percent_Identity=32.484076433121, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27477045, Length=115, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=47.2491909385113, Blast_Score=237, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=30.0675675675676, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=299, Percent_Identity=26.7558528428094, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24665753, Length=318, Percent_Identity=34.5911949685535, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33347; Mature: 33215

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGPRTGSQTAFIFPGQGSQAVGMGKALADNFPAAKAVFDEVDAALNESLTQVMWDGPI
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DALTLTANAQPALMAVSLAALRVLETEAGLDLAREAAFVAGHSLGEYSALAAAGALTITE
CEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AARLLRIRGRAMQEAVPVGEGAMAALLGLDYDQAVAVAAEAAGDDVCEAANDNAPGQVVV
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEE
SGTKAAVERAIVIAKEKGAMKALLLPVSAPFHCRLMGPAAEAMEVALSGSTVMTPRVPLV
ECHHHHHHHEEEEEECCCCEEEEEEECCCCEEEEEECCHHHHHHHHCCCCEEECCCCCEE
ANVRASPVTDPAEIVRLLVEQVTGTVRWRESVIYMAGAGVTRMVEVGAGKVLCGLVKRID
ECCCCCCCCCHHHHHHHHHHHHHCCCEEHHEEEEEECCCHHHHHHHCCCHHHHHHHHHHH
KSVSASAVGTPEDVAAFIAARNAAASAA
HHHCCCCCCCHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure 
SDGPRTGSQTAFIFPGQGSQAVGMGKALADNFPAAKAVFDEVDAALNESLTQVMWDGPI
CCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DALTLTANAQPALMAVSLAALRVLETEAGLDLAREAAFVAGHSLGEYSALAAAGALTITE
CEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AARLLRIRGRAMQEAVPVGEGAMAALLGLDYDQAVAVAAEAAGDDVCEAANDNAPGQVVV
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCCCCCEEEE
SGTKAAVERAIVIAKEKGAMKALLLPVSAPFHCRLMGPAAEAMEVALSGSTVMTPRVPLV
ECHHHHHHHEEEEEECCCCEEEEEEECCCCEEEEEECCHHHHHHHHCCCCEEECCCCCEE
ANVRASPVTDPAEIVRLLVEQVTGTVRWRESVIYMAGAGVTRMVEVGAGKVLCGLVKRID
ECCCCCCCCCHHHHHHHHHHHHHCCCEEHHEEEEEECCCHHHHHHHCCCHHHHHHHHHHH
KSVSASAVGTPEDVAAFIAARNAAASAA
HHHCCCCCCCHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]