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The map label for this gene is yfhC [C]

Identifier: 154247024

GI number: 154247024

Start: 3436923

End: 3437366

Strand: Direct

Name: yfhC [C]

Synonym: Xaut_3095

Alternate gene names: 154247024

Gene position: 3436923-3437366 (Clockwise)

Preceding gene: 154247021

Following gene: 154247031

Centisome position: 64.74

GC content: 68.47

Gene sequence:

>444_bases
ATGTCCGGAACCTATATGCAGATGGCGCTGAACGAGGCGCGGGCCGCCGCAGAGCGCGGCGAGGTACCGGTGGGTGCCGT
CCTGGTGCGCGGCGCCGAGGTGATCGCCCGCGACGGCAACCGCACCCGGGAACTCAATGATCCCACCGCCCACGCCGAGG
TCCTGGTGCTGCGCACAGCAGGCGCGCGGCTGAAATCCGAGCGCCTGGTCAACTGCGATCTCTACGTGACGCTGGAGCCC
TGCGCCATGTGCGCGGCGGCGCTTTCCTTCGCGCGCATCCGCCGACTTTATTATGGCGCGTCCGATCCCAAGGGGGGCGG
GGTAGAGCACGGGCCGCGCTTTTTCTCCCAGCCCACCTGCCACCACATGCCCGAAGTCTATGGCGGCATCGCCGAGCGCC
AGGCCGCCGAGGTGCTGCGCAGCTTCTTTCAGGATCGCAGGTAG

Upstream 100 bases:

>100_bases
GAACGCGGTTCTTGTCCTTGCGGGGCGGTGATGTGCGCGGCATGAGGGGCAGTTAGCACAGGCGAGGCGGCGCGGCGAGC
GCGGCGATGACAGAGGCACC

Downstream 100 bases:

>100_bases
CCGTCGCCCCGGAGCAATCGAGGCCTTCAGCTGGACGCCTTCAGGTCGATGAAGTCCCGGTTGTTCTGCTCATACCTGAA
ATTGTAGGGCTTGCCTTCCG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSGTYMQMALNEARAAAERGEVPVGAVLVRGAEVIARDGNRTRELNDPTAHAEVLVLRTAGARLKSERLVNCDLYVTLEP
CAMCAAALSFARIRRLYYGASDPKGGGVEHGPRFFSQPTCHHMPEVYGGIAERQAAEVLRSFFQDRR

Sequences:

>Translated_147_residues
MSGTYMQMALNEARAAAERGEVPVGAVLVRGAEVIARDGNRTRELNDPTAHAEVLVLRTAGARLKSERLVNCDLYVTLEP
CAMCAAALSFARIRRLYYGASDPKGGGVEHGPRFFSQPTCHHMPEVYGGIAERQAAEVLRSFFQDRR
>Mature_146_residues
SGTYMQMALNEARAAAERGEVPVGAVLVRGAEVIARDGNRTRELNDPTAHAEVLVLRTAGARLKSERLVNCDLYVTLEPC
AMCAAALSFARIRRLYYGASDPKGGGVEHGPRFFSQPTCHHMPEVYGGIAERQAAEVLRSFFQDRR

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=30.9210526315789, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=42.6573426573427, Blast_Score=113, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17554608, Length=114, Percent_Identity=34.2105263157895, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=150, Percent_Identity=32.6666666666667, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=34.2465753424658, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16123; Mature: 15991

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTYMQMALNEARAAAERGEVPVGAVLVRGAEVIARDGNRTRELNDPTAHAEVLVLRTA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEECC
GARLKSERLVNCDLYVTLEPCAMCAAALSFARIRRLYYGASDPKGGGVEHGPRFFSQPTC
CCCCCCCCEECCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
HHMPEVYGGIAERQAAEVLRSFFQDRR
HCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGTYMQMALNEARAAAERGEVPVGAVLVRGAEVIARDGNRTRELNDPTAHAEVLVLRTA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEECC
GARLKSERLVNCDLYVTLEPCAMCAAALSFARIRRLYYGASDPKGGGVEHGPRFFSQPTC
CCCCCCCCEECCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
HHMPEVYGGIAERQAAEVLRSFFQDRR
HCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA