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The map label for this gene is trpS [H]

Identifier: 154247014

GI number: 154247014

Start: 3426733

End: 3427770

Strand: Direct

Name: trpS [H]

Synonym: Xaut_3085

Alternate gene names: 154247014

Gene position: 3426733-3427770 (Clockwise)

Preceding gene: 154247013

Following gene: 154247015

Centisome position: 64.55

GC content: 66.38

Gene sequence:

>1038_bases
ATGGCGGCGGTCGCGGATCGCGTGTTTTCCGGTGTGCAGCCCACGGGCAACCTGCACCTCGGCAATTATCTCGGCGCCAT
TAAGCGCTTCGTGGCGCTGCAGGAGAGCCACGAGTGCATCTATTGCGTGGTGGACCTCCACGCCATCACCGTGTGGCAGG
ACCCGGTGGAGCTGAAGCGCCACATCCGCGAGGTTACCGCCGCCTTCATCGCCTGCGGCATCGACCCCAAGGCGCACATC
GTGTTCAACCAGAGTCAGGTGTCGGGCCACGCGGAATTGGCCTGGATCTTCAATTGCGTCGCCCGCATGGGCTGGCTCAA
CCGTATGACCCAGTTCAAGGAGAAGGCCGGCAAGGACCGCGAGAACGTCTCGGTGGGCCTGTTCGCCTATCCCGACCTGA
TGGCGGCCGACATCCTGCTCTATCGCGCCACCCACGTGCCGGTGGGCGAGGACCAGAAGCAGCACCTGGAGCTGACGCGC
GACATCGCGCAGAAGTTCAACACGGATTTTGGCCCCTCTATCGCCGCGCACGGCCACGCGGACGGCTACTTCCCCCTCAC
CGAGCCGCTGATCGCCGGGCCCGCCACCCGGGTGATGAGCCTGCGCGACGGCGCCAAGAAGATGTCCAAGTCGGACCCCT
CCGACTTCTCCCGCATCAACCTGACCGATGACCGCGACACCATCGCCGGCAAGGTGCGCAAGGCGAAGACCGATCCCGAG
CCCCTGCCCACCGAGGAAGAGGGCCTCAAGGGCCGTCCCGAGGCGGACAATCTGGTCGGCATCTTCGCCGCGCTCTCCGA
CCGCACCAAGGCCGATGTGCTGAAGGACTACGGCACCGCCCAGTTCTCTGCCTTCAAGGCGGCGCTGGTGGATCTGGCGG
TGGAGAAGCTCGGCCCCATCGGCGCCGAGATGCAGCGCCTGATGGCGGAGCCCGCCGCGATCGACGCCATCCTCATCGAC
GGCGCGGATCGTGCCCGCGTCATCGCCGACCAGACCATCGCCGAGGTGAAGGACATCGTTGGCCTGGTGCGCGGCTGA

Upstream 100 bases:

>100_bases
AGGCTGCGTCGGGCGAAAGCCCTCGCCGCGCCAAGGTCCCCGCGGTGCCTTGCCCCCGCAAGGCTTTTACGAGCGGTGCG
CCGCTCTTTTGGAGGTCGCC

Downstream 100 bases:

>100_bases
GCCGGGGCGGCGCACCGCCGCCTTGCTCCCTCCGCGCCTCCCGCCTAATGCTGGGGGCGAAACGGCGTCTGCCGAGGAGG
CCCCATGTCGCAGATGAACG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAAVADRVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPVELKRHIREVTAAFIACGIDPKAHI
VFNQSQVSGHAELAWIFNCVARMGWLNRMTQFKEKAGKDRENVSVGLFAYPDLMAADILLYRATHVPVGEDQKQHLELTR
DIAQKFNTDFGPSIAAHGHADGYFPLTEPLIAGPATRVMSLRDGAKKMSKSDPSDFSRINLTDDRDTIAGKVRKAKTDPE
PLPTEEEGLKGRPEADNLVGIFAALSDRTKADVLKDYGTAQFSAFKAALVDLAVEKLGPIGAEMQRLMAEPAAIDAILID
GADRARVIADQTIAEVKDIVGLVRG

Sequences:

>Translated_345_residues
MAAVADRVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPVELKRHIREVTAAFIACGIDPKAHI
VFNQSQVSGHAELAWIFNCVARMGWLNRMTQFKEKAGKDRENVSVGLFAYPDLMAADILLYRATHVPVGEDQKQHLELTR
DIAQKFNTDFGPSIAAHGHADGYFPLTEPLIAGPATRVMSLRDGAKKMSKSDPSDFSRINLTDDRDTIAGKVRKAKTDPE
PLPTEEEGLKGRPEADNLVGIFAALSDRTKADVLKDYGTAQFSAFKAALVDLAVEKLGPIGAEMQRLMAEPAAIDAILID
GADRARVIADQTIAEVKDIVGLVRG
>Mature_344_residues
AAVADRVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPVELKRHIREVTAAFIACGIDPKAHIV
FNQSQVSGHAELAWIFNCVARMGWLNRMTQFKEKAGKDRENVSVGLFAYPDLMAADILLYRATHVPVGEDQKQHLELTRD
IAQKFNTDFGPSIAAHGHADGYFPLTEPLIAGPATRVMSLRDGAKKMSKSDPSDFSRINLTDDRDTIAGKVRKAKTDPEP
LPTEEEGLKGRPEADNLVGIFAALSDRTKADVLKDYGTAQFSAFKAALVDLAVEKLGPIGAEMQRLMAEPAAIDAILIDG
ADRARVIADQTIAEVKDIVGLVRG

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=338, Percent_Identity=42.0118343195266, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=50.8021390374332, Blast_Score=203, Evalue=2e-52,
Organism=Escherichia coli, GI1789786, Length=336, Percent_Identity=40.1785714285714, Blast_Score=268, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=34.3108504398827, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=34.3108504398827, Blast_Score=197, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=354, Percent_Identity=38.135593220339, Blast_Score=220, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24666151, Length=338, Percent_Identity=39.9408284023669, Blast_Score=238, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37654; Mature: 37523

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVADRVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPVELKR
CCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCHHHHHH
HIREVTAAFIACGIDPKAHIVFNQSQVSGHAELAWIFNCVARMGWLNRMTQFKEKAGKDR
HHHHHHHHHHHCCCCCCEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENVSVGLFAYPDLMAADILLYRATHVPVGEDQKQHLELTRDIAQKFNTDFGPSIAAHGHA
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DGYFPLTEPLIAGPATRVMSLRDGAKKMSKSDPSDFSRINLTDDRDTIAGKVRKAKTDPE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
PLPTEEEGLKGRPEADNLVGIFAALSDRTKADVLKDYGTAQFSAFKAALVDLAVEKLGPI
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
GAEMQRLMAEPAAIDAILIDGADRARVIADQTIAEVKDIVGLVRG
HHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAVADRVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPVELKR
CHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCHHHHHH
HIREVTAAFIACGIDPKAHIVFNQSQVSGHAELAWIFNCVARMGWLNRMTQFKEKAGKDR
HHHHHHHHHHHCCCCCCEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENVSVGLFAYPDLMAADILLYRATHVPVGEDQKQHLELTRDIAQKFNTDFGPSIAAHGHA
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DGYFPLTEPLIAGPATRVMSLRDGAKKMSKSDPSDFSRINLTDDRDTIAGKVRKAKTDPE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
PLPTEEEGLKGRPEADNLVGIFAALSDRTKADVLKDYGTAQFSAFKAALVDLAVEKLGPI
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
GAEMQRLMAEPAAIDAILIDGADRARVIADQTIAEVKDIVGLVRG
HHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]