Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 154246902

GI number: 154246902

Start: 3292252

End: 3293466

Strand: Direct

Name: namA [H]

Synonym: Xaut_2970

Alternate gene names: 154246902

Gene position: 3292252-3293466 (Clockwise)

Preceding gene: 154246900

Following gene: 154246905

Centisome position: 62.01

GC content: 64.53

Gene sequence:

>1215_bases
GTGGCGGATCGTGCAACCCCAATGACGACACCGCTCGAAGCAGACCAAAGCCAATTACAACGAAGAGAGACGTACCAGAT
GACGCTGTTTGAACCATTCCTGCTGCGCGGTGTAACGCTAAAGAACCGGGTGGTCGTCTCACCGATGAGCCAGTACCGCG
CGCAGCACGGCGTGGCGAACGACTGGCACTTGGTCCACCTCGGTCGGTTCGCACTCGGAGGCGCCGCGCTGGTGTTCTGC
GAGGCTACTGCGGTGCAGGAGCATGGCCGGCGTACACATGGCGACCTCGGGATATGGTCGGACGCCCACATCGACCGGCT
CGCGGCGGTCACTCGCTTCCTCTCGCAAGAGGGAGCAGTTGCAGGCATCCAGCTCGCCCATGCGGGCCGCAAGGCGAGCG
AACGCCGCCCCTGGCACGGTGAGACACCGGTCGACTCGGAAGACATCGCACAGCGCGGTGAAAAACCGTGGGCTGCACTC
GGGCCGAGTGCGATCCCATACGCGGAAGGCTGGCCTGCTCCGGCCGCGATGAGCATCGAGGACATCAGGGAAGTGATCGC
GTCGTTCCGAATTGCCGCTGAGCGAGCACGCGAGGCCGGCTTCCGGGTGATCGAGGTCTACGCCGCGCATGGGTTTCTCA
TCCACCAGTTTTACTCGCCGCTCGCGAACCAACGGCGCGATGACTACGGCGGAAGCCTCGAAGGACGATGCCGTCTGGCA
CTCGAGATCGCCGCAGCGATCCGCGAGGTTTGGCCAGACGAATACCCACTGGTCTTCCGCCTATCGGTCACCGACTGGCA
TCCCGAGGGCTGGCAAGTGGACGACACAATCTACCTCGCACAACGACTGAAGGACCTCGGCGTCGACGCGATCGACTGCT
CAAGCGGCGGCATCTCAGGACGGGAACGTCCGCAGGGCATGACCCTCGAGCACGGCTATCAGCTCGCCCTCGCCGCGCGG
GTGAAGACGGCAGCACGCATCGCGACGATCGGTGTCGGACTTCTTTGGGACCCGAAGCTGGTCGACCGCTCGATCGACCA
AGGCGATATCGACCTCGTCGCACTCGGTCGCGAACTGCTGGAGGACCCGAACTGGCCATTGCAGGCGGCCCGCGAACTTG
GCGCCGACGGGGTTCATGGGATGTGGCACCCGGAGTTCGGGTGGTGGCTCGAGAAACGGGCGCGGGCTGTCCGCAGACTC
GGGATACGCAAGTGA

Upstream 100 bases:

>100_bases
GCGGCCCTGTATGCTGCGCTGCGCCGACTGCACCTCCGTCATCGGACGGTTTGTCAGGACTCGAGATTCTGCGTGGCTGG
ACGCTGCGAGGGTCGGCATC

Downstream 100 bases:

>100_bases
TCGACCATTGATCATCAACAACGCCCTCGGCCCGAAATCCCGGCGCGATTGCTCTTGCCGCGACCCAGGATAGATACAAC
ATCCCTTAGGACAGGAACTC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MADRATPMTTPLEADQSQLQRRETYQMTLFEPFLLRGVTLKNRVVVSPMSQYRAQHGVANDWHLVHLGRFALGGAALVFC
EATAVQEHGRRTHGDLGIWSDAHIDRLAAVTRFLSQEGAVAGIQLAHAGRKASERRPWHGETPVDSEDIAQRGEKPWAAL
GPSAIPYAEGWPAPAAMSIEDIREVIASFRIAAERAREAGFRVIEVYAAHGFLIHQFYSPLANQRRDDYGGSLEGRCRLA
LEIAAAIREVWPDEYPLVFRLSVTDWHPEGWQVDDTIYLAQRLKDLGVDAIDCSSGGISGRERPQGMTLEHGYQLALAAR
VKTAARIATIGVGLLWDPKLVDRSIDQGDIDLVALGRELLEDPNWPLQAARELGADGVHGMWHPEFGWWLEKRARAVRRL
GIRK

Sequences:

>Translated_404_residues
MADRATPMTTPLEADQSQLQRRETYQMTLFEPFLLRGVTLKNRVVVSPMSQYRAQHGVANDWHLVHLGRFALGGAALVFC
EATAVQEHGRRTHGDLGIWSDAHIDRLAAVTRFLSQEGAVAGIQLAHAGRKASERRPWHGETPVDSEDIAQRGEKPWAAL
GPSAIPYAEGWPAPAAMSIEDIREVIASFRIAAERAREAGFRVIEVYAAHGFLIHQFYSPLANQRRDDYGGSLEGRCRLA
LEIAAAIREVWPDEYPLVFRLSVTDWHPEGWQVDDTIYLAQRLKDLGVDAIDCSSGGISGRERPQGMTLEHGYQLALAAR
VKTAARIATIGVGLLWDPKLVDRSIDQGDIDLVALGRELLEDPNWPLQAARELGADGVHGMWHPEFGWWLEKRARAVRRL
GIRK
>Mature_403_residues
ADRATPMTTPLEADQSQLQRRETYQMTLFEPFLLRGVTLKNRVVVSPMSQYRAQHGVANDWHLVHLGRFALGGAALVFCE
ATAVQEHGRRTHGDLGIWSDAHIDRLAAVTRFLSQEGAVAGIQLAHAGRKASERRPWHGETPVDSEDIAQRGEKPWAALG
PSAIPYAEGWPAPAAMSIEDIREVIASFRIAAERAREAGFRVIEVYAAHGFLIHQFYSPLANQRRDDYGGSLEGRCRLAL
EIAAAIREVWPDEYPLVFRLSVTDWHPEGWQVDDTIYLAQRLKDLGVDAIDCSSGGISGRERPQGMTLEHGYQLALAARV
KTAARIATIGVGLLWDPKLVDRSIDQGDIDLVALGRELLEDPNWPLQAARELGADGVHGMWHPEFGWWLEKRARAVRRLG
IRK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=27.8592375366569, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789463, Length=335, Percent_Identity=25.6716417910448, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=292, Percent_Identity=28.4246575342466, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17559804, Length=277, Percent_Identity=29.2418772563177, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=303, Percent_Identity=26.7326732673267, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=327, Percent_Identity=26.9113149847095, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=354, Percent_Identity=24.2937853107345, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=361, Percent_Identity=25.207756232687, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=228, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 45004; Mature: 44872

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRATPMTTPLEADQSQLQRRETYQMTLFEPFLLRGVTLKNRVVVSPMSQYRAQHGVAN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCC
DWHLVHLGRFALGGAALVFCEATAVQEHGRRTHGDLGIWSDAHIDRLAAVTRFLSQEGAV
CEEEEEEHHHHHCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
AGIQLAHAGRKASERRPWHGETPVDSEDIAQRGEKPWAALGPSAIPYAEGWPAPAAMSIE
EEEEHHHCCCCHHCCCCCCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCHH
DIREVIASFRIAAERAREAGFRVIEVYAAHGFLIHQFYSPLANQRRDDYGGSLEGRCRLA
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LEIAAAIREVWPDEYPLVFRLSVTDWHPEGWQVDDTIYLAQRLKDLGVDAIDCSSGGISG
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCC
RERPQGMTLEHGYQLALAARVKTAARIATIGVGLLWDPKLVDRSIDQGDIDLVALGRELL
CCCCCCCCHHCCCEEHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHHH
EDPNWPLQAARELGADGVHGMWHPEFGWWLEKRARAVRRLGIRK
HCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADRATPMTTPLEADQSQLQRRETYQMTLFEPFLLRGVTLKNRVVVSPMSQYRAQHGVAN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCC
DWHLVHLGRFALGGAALVFCEATAVQEHGRRTHGDLGIWSDAHIDRLAAVTRFLSQEGAV
CEEEEEEHHHHHCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
AGIQLAHAGRKASERRPWHGETPVDSEDIAQRGEKPWAALGPSAIPYAEGWPAPAAMSIE
EEEEHHHCCCCHHCCCCCCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCHH
DIREVIASFRIAAERAREAGFRVIEVYAAHGFLIHQFYSPLANQRRDDYGGSLEGRCRLA
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
LEIAAAIREVWPDEYPLVFRLSVTDWHPEGWQVDDTIYLAQRLKDLGVDAIDCSSGGISG
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCC
RERPQGMTLEHGYQLALAARVKTAARIATIGVGLLWDPKLVDRSIDQGDIDLVALGRELL
CCCCCCCCHHCCCEEHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHHH
EDPNWPLQAARELGADGVHGMWHPEFGWWLEKRARAVRRLGIRK
HCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA