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The map label for this gene is nudL [H]

Identifier: 154246885

GI number: 154246885

Start: 3277509

End: 3278189

Strand: Direct

Name: nudL [H]

Synonym: Xaut_2950

Alternate gene names: 154246885

Gene position: 3277509-3278189 (Clockwise)

Preceding gene: 154246884

Following gene: 154246886

Centisome position: 61.74

GC content: 67.55

Gene sequence:

>681_bases
ATGACGCACCACACCGACGCGGAGGCGCCCGTCGCGACTGGAACAGCCGACGGCCTTTCTGATTTTCTCGCCCGCGCGGC
GGCGCGCCTGTCTTCCGAGCCGCCGCCCTTATATTCGCAGGCGGCCTTCCTCGGGCTCAATGGCGATCATGCCCTTCAGC
CGGAGAAGGCGAGCCTCGCGCCGGCGGCGACGCCACGCCATGCGGCGGTGCTGGTTCCCGTGGTGGCCCGGCCGGAGCCT
ACCATCCTGCTCACCCTGCGGTCGTCGAGCCTTTCCAACCATGCCGGGCAGATCGCCTTTCCCGGCGGGCGGGTGGACCC
CGGCGACCGGGACGAGCTCGATGCCGCCCTGCGGGAGGCGCGAGAGGAAGTGGGGCTCGATTCGCGGCTGGTACGGCCGC
TCGGCTATCTGGACGGCTATCTCTCCGGCACCGGATTCTGGATTGCGCCGGCAGTGGGGCTGGTCGATCCGGCCTACACG
CTGACCCTTAATCCGGCGGAGGTGGATGAGGCGTTCGAGGTACCGCTCAGCTTCCTCATGAGCCCGCGCAATCATGAGCG
CCAGTCGCGCGACTGGAAGGGCACGCTGCGCCATTTCTACGTTATGCCTTATGAAGGGCGGAACATCTGGGGGGCGACCG
CAGGCATGCTGCGCAACCTCTACGAAAAGGTCTACGCCTGA

Upstream 100 bases:

>100_bases
GTGTCCCCATGTTCGGGGTTGGCTCGGCGGGCGTATTCTTCCCCATCCTGCCGGCGGCCGATCTGGGGCTCGAATTTGGG
GCCGATGTGGATTTTTCCGA

Downstream 100 bases:

>100_bases
TGCTGCGCAGCTTCCTGGTCGAGTTCGCGCTCTTTCTCACGCCGTTCCTGCTCTACGGCGCTCTGCTGCTTGCCACCAAG
GGCTCGGTGGTGCCGGAGCA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTHHTDAEAPVATGTADGLSDFLARAAARLSSEPPPLYSQAAFLGLNGDHALQPEKASLAPAATPRHAAVLVPVVARPEP
TILLTLRSSSLSNHAGQIAFPGGRVDPGDRDELDAALREAREEVGLDSRLVRPLGYLDGYLSGTGFWIAPAVGLVDPAYT
LTLNPAEVDEAFEVPLSFLMSPRNHERQSRDWKGTLRHFYVMPYEGRNIWGATAGMLRNLYEKVYA

Sequences:

>Translated_226_residues
MTHHTDAEAPVATGTADGLSDFLARAAARLSSEPPPLYSQAAFLGLNGDHALQPEKASLAPAATPRHAAVLVPVVARPEP
TILLTLRSSSLSNHAGQIAFPGGRVDPGDRDELDAALREAREEVGLDSRLVRPLGYLDGYLSGTGFWIAPAVGLVDPAYT
LTLNPAEVDEAFEVPLSFLMSPRNHERQSRDWKGTLRHFYVMPYEGRNIWGATAGMLRNLYEKVYA
>Mature_225_residues
THHTDAEAPVATGTADGLSDFLARAAARLSSEPPPLYSQAAFLGLNGDHALQPEKASLAPAATPRHAAVLVPVVARPEPT
ILLTLRSSSLSNHAGQIAFPGGRVDPGDRDELDAALREAREEVGLDSRLVRPLGYLDGYLSGTGFWIAPAVGLVDPAYTL
TLNPAEVDEAFEVPLSFLMSPRNHERQSRDWKGTLRHFYVMPYEGRNIWGATAGMLRNLYEKVYA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=38.0645161290323, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32469515, Length=66, Percent_Identity=54.5454545454545, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788115, Length=155, Percent_Identity=40.6451612903226, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17536993, Length=167, Percent_Identity=30.5389221556886, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI18859683, Length=177, Percent_Identity=36.1581920903955, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 24455; Mature: 24324

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHHTDAEAPVATGTADGLSDFLARAAARLSSEPPPLYSQAAFLGLNGDHALQPEKASLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
PAATPRHAAVLVPVVARPEPTILLTLRSSSLSNHAGQIAFPGGRVDPGDRDELDAALREA
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
REEVGLDSRLVRPLGYLDGYLSGTGFWIAPAVGLVDPAYTLTLNPAEVDEAFEVPLSFLM
HHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHC
SPRNHERQSRDWKGTLRHFYVMPYEGRNIWGATAGMLRNLYEKVYA
CCCCCCHHCCCHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THHTDAEAPVATGTADGLSDFLARAAARLSSEPPPLYSQAAFLGLNGDHALQPEKASLA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
PAATPRHAAVLVPVVARPEPTILLTLRSSSLSNHAGQIAFPGGRVDPGDRDELDAALREA
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
REEVGLDSRLVRPLGYLDGYLSGTGFWIAPAVGLVDPAYTLTLNPAEVDEAFEVPLSFLM
HHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHC
SPRNHERQSRDWKGTLRHFYVMPYEGRNIWGATAGMLRNLYEKVYA
CCCCCCHHCCCHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]