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The map label for this gene is mtnC

Identifier: 154246848

GI number: 154246848

Start: 3236067

End: 3236732

Strand: Direct

Name: mtnC

Synonym: Xaut_2913

Alternate gene names: 154246848

Gene position: 3236067-3236732 (Clockwise)

Preceding gene: 154246846

Following gene: 154246849

Centisome position: 60.96

GC content: 67.12

Gene sequence:

>666_bases
ATGACCATAAAGGCCATCCTGACCGACATCGAGGGCGCCGCCGGTCCCGCGTCCTTCCTGAAGGACATTTTGCTGCCTTA
TGCCCGGGAGCATCTCGGCGCCTTCATCGCGGCCCACGCCGAGGATGACGGCATCGAGGAGGCGCTGGAGGAAGCCGGGC
GCCTCATGGGCGGCTTCTCGCTCAAGCCCGACGAGGCCGAGGCGCTGCTGCAGCGCTGGATGAAGCAGGGCCGCAATCCG
ACACCCCTCAAGATCATCCAGGGCCGGATCTGGCAGCAGGGCTATGAGGCCGGCGCCTTCACCGCCGAGATCTTCCCCGA
TGTGGCGCCGAGCCTGGGCGCCTGGAAGAATGCCGGGATCCGCCTGTTCACCTATTCGTCCAGCTCCGAGCTGGCGCAGA
GGCTGTGGCTCGGGTCGGCGGGGGCGGAGGTGTTCGAGGGCTTCTTCGATACCCGCGTCGGCCAGAAGCTGGAGGAGGAA
TCCTACAAGGCCATCGCCGAGCAACTGGCTCTGCCGGCTGCGGAAATTCTGGTGCTGTCCGGGAATGAGGATGAGCTGGA
TGCCGCCAAGGCCGCCGGCCTTGCCACCGCGCTGATCGCGCGCGAGGGCGGCGGGGGCGGCAACCATCCGGTGGCCGCCG
ATTTCGCGTCGGTGACCATTGGATAG

Upstream 100 bases:

>100_bases
GTGAAGGCCTGATCACGGCACGGAGCACCCGGTCCATGGCGATTTCCGAACAATCAGGGGAGCATGTCGCGTCGCGCCCG
GCGCCGGTGGGGGCTCGTCC

Downstream 100 bases:

>100_bases
GGCGAATGGCGGTGGGCGCGGCGCATTTCACCGATTGAAAGCTGGGACAGGGCACGCTTTACATGGCACGCTTCACCGTA
CAGACGCGCAACGGCGATCA

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFSLKPDEAEALLQRWMKQGRNP
TPLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGIRLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEE
SYKAIAEQLALPAAEILVLSGNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG

Sequences:

>Translated_221_residues
MTIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFSLKPDEAEALLQRWMKQGRNP
TPLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGIRLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEE
SYKAIAEQLALPAAEILVLSGNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG
>Mature_220_residues
TIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFSLKPDEAEALLQRWMKQGRNPT
PLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGIRLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEES
YKAIAEQLALPAAEILVLSGNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family

Homologues:

Organism=Homo sapiens, GI10864017, Length=228, Percent_Identity=32.8947368421053, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115533232, Length=224, Percent_Identity=32.5892857142857, Blast_Score=126, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320797, Length=233, Percent_Identity=30.9012875536481, Blast_Score=95, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281360080, Length=218, Percent_Identity=33.0275229357798, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644163, Length=218, Percent_Identity=33.0275229357798, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNC_XANP2 (A7IJF6)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417806.1
- ProteinModelPortal:   A7IJF6
- SMR:   A7IJF6
- STRING:   A7IJF6
- GeneID:   5422512
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2913
- eggNOG:   COG4229
- HOGENOM:   HBG294242
- OMA:   TTDLNFI
- ProtClustDB:   CLSK866737
- BioCyc:   XAUT78245:XAUT_2913-MONOMER
- HAMAP:   MF_01681
- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR20371
- TIGRFAMs:   TIGR01691

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: =3.1.3.77

Molecular weight: Translated: 23430; Mature: 23298

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFS
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LKPDEAEALLQRWMKQGRNPTPLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGI
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCE
RLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEESYKAIAEQLALPAAEILVLS
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEC
GNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEECC
>Mature Secondary Structure 
TIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFS
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LKPDEAEALLQRWMKQGRNPTPLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGI
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCE
RLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEESYKAIAEQLALPAAEILVLS
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEC
GNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA