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The map label for this gene is lptD [H]

Identifier: 154246775

GI number: 154246775

Start: 3163006

End: 3165534

Strand: Reverse

Name: lptD [H]

Synonym: Xaut_2836

Alternate gene names: 154246775

Gene position: 3165534-3163006 (Counterclockwise)

Preceding gene: 154246776

Following gene: 154246774

Centisome position: 59.63

GC content: 64.1

Gene sequence:

>2529_bases
ATGACGGTCGGGCTTCCCCCCGCCGTAGGCAGCATCACCGGGGACCGGCGCCGCGTCGCGCGCCGGACGGGGATGCTTGC
GTCCGCGGCCAGCCTCTTCCTGATGGCAGCGAGCTTCTTCGCATCCGCTCCCGCGGTTGCTCAGACGCAGGGCGGCCAGC
AGCCCAACGTCACCTCCAGCGCGCTCGGCTCGGGCTTCGCGGGAACCCGCAAGCTCGACCCGAACCAGAAGATGCTGGTG
ACGGCTGACCAGCTTGAATACGACTACCAGAAGGAAACGGTCTCCGCCGTCGGCACGGTCCAGATCTATTATGACGGCTC
GACCCTGGAGGCGAACCGGGTGGTGCTCGACCGCAAGGCGAACACCCTGTTTGCCCAGGGCAATGTCCGGCTGAAGGACA
AGGACGGCAAGATCGTCACCGCCGACAATTTGGAACTGACCCAGGACTTCAAGCAGGGCTTCATCGATTCCCTGCGTCTC
GACACCCCGGACAAGACCCACTTCGCCGCCACCCGCGCCGATCGCACGGACGGCAACGTGACCGTGTTCCAGAACGGCGT
CTACACCGCCTGCGAACCGTGCAAGGACGACCCGAGCAAGCCTCCGCTGTGGCAGATCAAGGCCAAAAAGATCGTCCACA
ACGAAGACGAGAAGATGATCTACTACCAGGATGCCTGGGTAGAGTTCTTCGGGTTTCCGGTGGCCTATTTCCCGTATCTG
TCGTCGCCCGACCCGACGGTGAAGCGCAAGACCGGCTTCCTCATTCCGGAATTCTTCTCGTCGAGCCAGATCGGCTATGG
CGTCGGCACGCCGTTCTTCTGGAACATCGCGCCCGACCGCGACCTGACCCTGACGCCCGCCTTCACCACCAAGCAGGGCG
TGTTGATGCAGGGCGAGTGGCGCCAGCGCCTGATGAACGGCGCCTACACCATCCGCGCCGCTGGCATCCTGCAGCAGGAC
AAGGACGCCTTCACCACCACCTCCAACGGGGTGACCGATTATCTGCCAGGCTACCGCGACAACCGCGGCTCGCTTCAGAG
CACCGGCGCGTTCGCGCTGAACAAGTTCTGGACCTTCGGCTGGGACGGCACGCTGGTCTCCGACCGCACCTTCCTGCAGG
ACTACAACCTGATCGGCGACGGGGTCACCACCAAGACCTCCACCGTCTACCTCACCGGCCAGGGCGACCGCTCCTTCTTC
GACGTGCGCGGGCTCTATTTCCTCGGCCTGTCGGTAACCGACAACCAGGACCTCCAGCCCATCGTCGGCACGCTCAATTA
CAACAAGGTGTTCGACAAGCCCCTGTGGGGCGGTGAATCCGGCATCAAGGTCAACCTCACCAGCCTCACCCGCCAGGAGG
CCGACTTCATCGGCACCTCGGCGCTCACCTCCAACGTCGGCGCCACGGGCATCCCCACCGGCTCCTGCGCGCTGATGAAC
CCCAATCCCGAGCAGTGCCTGCTGCGTGGCGCGCCGGGCGACTACACACGCCTGTCGGCGGAGCTCTACTGGAAGAAGGC
CATCACCGATCCGATGGGCCAGATCTGGACGCCGTTCGTGACCGCGCGGGTGGACGTCGCCTCCGTGGACACCGGCTACC
TGCCCTACAGCTACATGTATGGCGCCACCCTGCCCGGCCAGAACCCGCTCCAGTCCGGCAGCGACGACCTGATCCGCGGC
ATGCCGGCGGTGGGTCTCGACTATAAGTACCCCTTCATCTCCGCCGAGAGCTGGGGCACCCAGACCATTGAGCCGCGGGC
CCAGGTCATCATCCGTCCCAACGAGACGGACATCGGCAAGTTCCCGAACGAGGATGCCCAGAGCCTGGTGTTCGACGACA
CCAACCTGTTCGAGGTGAACAAATATTCGGGCTACGACCGGGTCGAGGGCGGCAGTCGCCTCAATCTCGGCGTGACCTAC
ACCGCCGCCATCAACGGCGCCGGCCTCGTCACCGCCGTGGTCGGCCAGTCCTACAACCTGTTCGGCCGGAACTCGTTCGC
CTATGGCGACATGGCCAATACCGGCCTCGAATCGGGCCTCGAGACCACGGCGTCGGACTACATCGCCAAGTTCGGCTACT
CGCCCACCAAGTATCTCGAGTTTGTGACCCGATTCCGGTTCGACAACGACAACCTCTCCATGCAGCGTTTCGAACTGCAG
GGGCGGGCGGAGCTGGACCGCTTCAACGTGGCCGTCACCTACGGCCGCTACGAGGCGCAGCCGCTGCTCGGCTATTACGA
CAAGCGCGAGGGCATCTACACCAACGCCTCGTACAAGCTGAACGACAATTGGGCCATCCGTGGCGCGGTGCGCTACGATT
TCGCCGCCGGCGAGTTCGACTACACGCTGGTGGGCCTCAGCTATATCGACGACTGCTTCACCCTCGCCCTCAACTACGTC
ACCGACTACACCCTGAACGGCCCCAATGCGGCGCCGGTCAACAAGGTGATGTTCCGCATCGGGCTGAGAACGCTTGGCGA
AGGCGGCTTCTCCACCTCGTTAGGCTCCAGCAGCGAAACCAACCAGTGA

Upstream 100 bases:

>100_bases
TCGGCGACGCGGGTTTTGTTCATCCCGTTGCTGCAGCATGGTTTCCTGCGGTAGCCGGGATTCTTCTGGGGGTCCTCATT
CTGTTGCATCGGGAGGACGG

Downstream 100 bases:

>100_bases
GGCGGCGCGCCGGCTGACCCGGCCGCGGCCTGTGCTGCGGTCCGCGAGGCAGGCCGCATTGCCGCCACAGGAAGGGGACA
CAAGTCGCCGTCTGACCTTC

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MTVGLPPAVGSITGDRRRVARRTGMLASAASLFLMAASFFASAPAVAQTQGGQQPNVTSSALGSGFAGTRKLDPNQKMLV
TADQLEYDYQKETVSAVGTVQIYYDGSTLEANRVVLDRKANTLFAQGNVRLKDKDGKIVTADNLELTQDFKQGFIDSLRL
DTPDKTHFAATRADRTDGNVTVFQNGVYTACEPCKDDPSKPPLWQIKAKKIVHNEDEKMIYYQDAWVEFFGFPVAYFPYL
SSPDPTVKRKTGFLIPEFFSSSQIGYGVGTPFFWNIAPDRDLTLTPAFTTKQGVLMQGEWRQRLMNGAYTIRAAGILQQD
KDAFTTTSNGVTDYLPGYRDNRGSLQSTGAFALNKFWTFGWDGTLVSDRTFLQDYNLIGDGVTTKTSTVYLTGQGDRSFF
DVRGLYFLGLSVTDNQDLQPIVGTLNYNKVFDKPLWGGESGIKVNLTSLTRQEADFIGTSALTSNVGATGIPTGSCALMN
PNPEQCLLRGAPGDYTRLSAELYWKKAITDPMGQIWTPFVTARVDVASVDTGYLPYSYMYGATLPGQNPLQSGSDDLIRG
MPAVGLDYKYPFISAESWGTQTIEPRAQVIIRPNETDIGKFPNEDAQSLVFDDTNLFEVNKYSGYDRVEGGSRLNLGVTY
TAAINGAGLVTAVVGQSYNLFGRNSFAYGDMANTGLESGLETTASDYIAKFGYSPTKYLEFVTRFRFDNDNLSMQRFELQ
GRAELDRFNVAVTYGRYEAQPLLGYYDKREGIYTNASYKLNDNWAIRGAVRYDFAAGEFDYTLVGLSYIDDCFTLALNYV
TDYTLNGPNAAPVNKVMFRIGLRTLGEGGFSTSLGSSSETNQ

Sequences:

>Translated_842_residues
MTVGLPPAVGSITGDRRRVARRTGMLASAASLFLMAASFFASAPAVAQTQGGQQPNVTSSALGSGFAGTRKLDPNQKMLV
TADQLEYDYQKETVSAVGTVQIYYDGSTLEANRVVLDRKANTLFAQGNVRLKDKDGKIVTADNLELTQDFKQGFIDSLRL
DTPDKTHFAATRADRTDGNVTVFQNGVYTACEPCKDDPSKPPLWQIKAKKIVHNEDEKMIYYQDAWVEFFGFPVAYFPYL
SSPDPTVKRKTGFLIPEFFSSSQIGYGVGTPFFWNIAPDRDLTLTPAFTTKQGVLMQGEWRQRLMNGAYTIRAAGILQQD
KDAFTTTSNGVTDYLPGYRDNRGSLQSTGAFALNKFWTFGWDGTLVSDRTFLQDYNLIGDGVTTKTSTVYLTGQGDRSFF
DVRGLYFLGLSVTDNQDLQPIVGTLNYNKVFDKPLWGGESGIKVNLTSLTRQEADFIGTSALTSNVGATGIPTGSCALMN
PNPEQCLLRGAPGDYTRLSAELYWKKAITDPMGQIWTPFVTARVDVASVDTGYLPYSYMYGATLPGQNPLQSGSDDLIRG
MPAVGLDYKYPFISAESWGTQTIEPRAQVIIRPNETDIGKFPNEDAQSLVFDDTNLFEVNKYSGYDRVEGGSRLNLGVTY
TAAINGAGLVTAVVGQSYNLFGRNSFAYGDMANTGLESGLETTASDYIAKFGYSPTKYLEFVTRFRFDNDNLSMQRFELQ
GRAELDRFNVAVTYGRYEAQPLLGYYDKREGIYTNASYKLNDNWAIRGAVRYDFAAGEFDYTLVGLSYIDDCFTLALNYV
TDYTLNGPNAAPVNKVMFRIGLRTLGEGGFSTSLGSSSETNQ
>Mature_841_residues
TVGLPPAVGSITGDRRRVARRTGMLASAASLFLMAASFFASAPAVAQTQGGQQPNVTSSALGSGFAGTRKLDPNQKMLVT
ADQLEYDYQKETVSAVGTVQIYYDGSTLEANRVVLDRKANTLFAQGNVRLKDKDGKIVTADNLELTQDFKQGFIDSLRLD
TPDKTHFAATRADRTDGNVTVFQNGVYTACEPCKDDPSKPPLWQIKAKKIVHNEDEKMIYYQDAWVEFFGFPVAYFPYLS
SPDPTVKRKTGFLIPEFFSSSQIGYGVGTPFFWNIAPDRDLTLTPAFTTKQGVLMQGEWRQRLMNGAYTIRAAGILQQDK
DAFTTTSNGVTDYLPGYRDNRGSLQSTGAFALNKFWTFGWDGTLVSDRTFLQDYNLIGDGVTTKTSTVYLTGQGDRSFFD
VRGLYFLGLSVTDNQDLQPIVGTLNYNKVFDKPLWGGESGIKVNLTSLTRQEADFIGTSALTSNVGATGIPTGSCALMNP
NPEQCLLRGAPGDYTRLSAELYWKKAITDPMGQIWTPFVTARVDVASVDTGYLPYSYMYGATLPGQNPLQSGSDDLIRGM
PAVGLDYKYPFISAESWGTQTIEPRAQVIIRPNETDIGKFPNEDAQSLVFDDTNLFEVNKYSGYDRVEGGSRLNLGVTYT
AAINGAGLVTAVVGQSYNLFGRNSFAYGDMANTGLESGLETTASDYIAKFGYSPTKYLEFVTRFRFDNDNLSMQRFELQG
RAELDRFNVAVTYGRYEAQPLLGYYDKREGIYTNASYKLNDNWAIRGAVRYDFAAGEFDYTLVGLSYIDDCFTLALNYVT
DYTLNGPNAAPVNKVMFRIGLRTLGEGGFSTSLGSSSETNQ

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=326, Percent_Identity=26.6871165644172, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 92724; Mature: 92592

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGLPPAVGSITGDRRRVARRTGMLASAASLFLMAASFFASAPAVAQTQGGQQPNVTSS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHH
ALGSGFAGTRKLDPNQKMLVTADQLEYDYQKETVSAVGTVQIYYDGSTLEANRVVLDRKA
HHCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHCCEEEEEEEEECCCEEECCEEEEECCC
NTLFAQGNVRLKDKDGKIVTADNLELTQDFKQGFIDSLRLDTPDKTHFAATRADRTDGNV
CEEEECCCEEEECCCCCEEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCE
TVFQNGVYTACEPCKDDPSKPPLWQIKAKKIVHNEDEKMIYYQDAWVEFFGFPVAYFPYL
EEEECCCEEECCCCCCCCCCCCEEEEEEHEEEECCCCCEEEEEEHHHHHHCCCHHCCCCC
SSPDPTVKRKTGFLIPEFFSSSQIGYGVGTPFFWNIAPDRDLTLTPAFTTKQGVLMQGEW
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEECCHH
RQRLMNGAYTIRAAGILQQDKDAFTTTSNGVTDYLPGYRDNRGSLQSTGAFALNKFWTFG
HHHHHCCCEEEEEECCCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEECCEEEEC
WDGTLVSDRTFLQDYNLIGDGVTTKTSTVYLTGQGDRSFFDVRGLYFLGLSVTDNQDLQP
CCCEEECCCHHHHCCCEECCCCCCCEEEEEEEECCCCCEEEECEEEEEEEEECCCCCCCH
IVGTLNYNKVFDKPLWGGESGIKVNLTSLTRQEADFIGTSALTSNVGATGIPTGSCALMN
HEEECCCCHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHCCCCCCCCCCCCEEEEC
PNPEQCLLRGAPGDYTRLSAELYWKKAITDPMGQIWTPFVTARVDVASVDTGYLPYSYMY
CCHHHHEEECCCCCHHEEEHHHHHHHHHCCCHHHHHCCEEEEEEEEEECCCCCCCCHHEE
GATLPGQNPLQSGSDDLIRGMPAVGLDYKYPFISAESWGTQTIEPRAQVIIRPNETDIGK
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCC
FPNEDAQSLVFDDTNLFEVNKYSGYDRVEGGSRLNLGVTYTAAINGAGLVTAVVGQSYNL
CCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCEEE
FGRNSFAYGDMANTGLESGLETTASDYIAKFGYSPTKYLEFVTRFRFDNDNLSMQRFELQ
CCCCCCCCCCCHHCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCEEEEEEEC
GRAELDRFNVAVTYGRYEAQPLLGYYDKREGIYTNASYKLNDNWAIRGAVRYDFAAGEFD
CCCCCEEEEEEEEECCEECCCHHCCCCCCCCEEECCEEEECCCEEEEEEEEEEEECCCCC
YTLVGLSYIDDCFTLALNYVTDYTLNGPNAAPVNKVMFRIGLRTLGEGGFSTSLGSSSET
EEEEEHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NQ
CC
>Mature Secondary Structure 
TVGLPPAVGSITGDRRRVARRTGMLASAASLFLMAASFFASAPAVAQTQGGQQPNVTSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHH
ALGSGFAGTRKLDPNQKMLVTADQLEYDYQKETVSAVGTVQIYYDGSTLEANRVVLDRKA
HHCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHCCEEEEEEEEECCCEEECCEEEEECCC
NTLFAQGNVRLKDKDGKIVTADNLELTQDFKQGFIDSLRLDTPDKTHFAATRADRTDGNV
CEEEECCCEEEECCCCCEEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCCE
TVFQNGVYTACEPCKDDPSKPPLWQIKAKKIVHNEDEKMIYYQDAWVEFFGFPVAYFPYL
EEEECCCEEECCCCCCCCCCCCEEEEEEHEEEECCCCCEEEEEEHHHHHHCCCHHCCCCC
SSPDPTVKRKTGFLIPEFFSSSQIGYGVGTPFFWNIAPDRDLTLTPAFTTKQGVLMQGEW
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEECCHH
RQRLMNGAYTIRAAGILQQDKDAFTTTSNGVTDYLPGYRDNRGSLQSTGAFALNKFWTFG
HHHHHCCCEEEEEECCCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEECCEEEEC
WDGTLVSDRTFLQDYNLIGDGVTTKTSTVYLTGQGDRSFFDVRGLYFLGLSVTDNQDLQP
CCCEEECCCHHHHCCCEECCCCCCCEEEEEEEECCCCCEEEECEEEEEEEEECCCCCCCH
IVGTLNYNKVFDKPLWGGESGIKVNLTSLTRQEADFIGTSALTSNVGATGIPTGSCALMN
HEEECCCCHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHCCCCCCCCCCCCEEEEC
PNPEQCLLRGAPGDYTRLSAELYWKKAITDPMGQIWTPFVTARVDVASVDTGYLPYSYMY
CCHHHHEEECCCCCHHEEEHHHHHHHHHCCCHHHHHCCEEEEEEEEEECCCCCCCCHHEE
GATLPGQNPLQSGSDDLIRGMPAVGLDYKYPFISAESWGTQTIEPRAQVIIRPNETDIGK
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCC
FPNEDAQSLVFDDTNLFEVNKYSGYDRVEGGSRLNLGVTYTAAINGAGLVTAVVGQSYNL
CCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCEEE
FGRNSFAYGDMANTGLESGLETTASDYIAKFGYSPTKYLEFVTRFRFDNDNLSMQRFELQ
CCCCCCCCCCCHHCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCEEEEEEEC
GRAELDRFNVAVTYGRYEAQPLLGYYDKREGIYTNASYKLNDNWAIRGAVRYDFAAGEFD
CCCCCEEEEEEEEECCEECCCHHCCCCCCCCEEECCEEEECCCEEEEEEEEEEEECCCCC
YTLVGLSYIDDCFTLALNYVTDYTLNGPNAAPVNKVMFRIGLRTLGEGGFSTSLGSSSET
EEEEEHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA