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The map label for this gene is ygjG [C]

Identifier: 154246666

GI number: 154246666

Start: 3021687

End: 3023123

Strand: Direct

Name: ygjG [C]

Synonym: Xaut_2727

Alternate gene names: 154246666

Gene position: 3021687-3023123 (Clockwise)

Preceding gene: 154246664

Following gene: 154246667

Centisome position: 56.92

GC content: 67.29

Gene sequence:

>1437_bases
GTGACATCCGCCCCCCTCTCGAACTCGACGGCCCACTGGCGTGCGCTGGATGCGGCGCACCACCTCCACCCCTTCTCCGA
TACCAAGGCGCTCAACGCGGAAGGGGTGCGGGTCATCACGCGGGCGGAAGGGGTCTATGTGTTCGACAGCGAGGGCAACA
GGATCCTCGACGGCATGTCGGGCCTGTGGTGCTCTCAGGTTGGCCACGGGCGCCGCGCCATCGTGGATGCCATCGCCCAG
CAGCTCCACCAGCTCGATTATTACAACACCTTCTTCAAGACCACCCATCCCGGCGCGGCGGAGCTGGCCGCCGCCATCTC
GGACGTGGCGCCGGCGCACATGAACCATGTGTTCTTCACCTCCGGCGGGTCGGAGGCGGTGGACACGGTGCTGCGCATGG
TGCGCCACTATTGGGCGGCGCTGGGCAAGCCGGAAAAGTCCATCTTCATCTCGCGGCGCAACGGCTATCACGGCTCCACC
CTCGGCGGGGCCTCGCTGGGCGGCATGAAGCCCATGCATGCCCAGGGCGGGCTGCCCATTCCCGGCATCATCCATGTGGC
GCAGCCCTATTGGTGGGCCGAAGGCGGGGAGATGGGCCGCGAGGAGTTCGGCCTGTTCGCCGCCCGCGAGGTAGCCCGCG
CCATCGACGAGGCGGGGCCGGAGAATGTGGCCGCCTTCATCGGCGAGCCGATCCAGGGGGCGGGCGGCGTCATCATTCCG
CCGGCCAATTACTGGCCGGAGGTGGAGAAGATCTGCCGCGAGCGTGATGTTCTTCTGGTGTGCGACGAGGTGATTTGCGG
TTTCGGCCGCACCGGGCGGTGGTTCGGCGCTGATTTCATGGGCGTGAAGCCGGATCTCATCACCTTCGCCAAGGGCATCA
CCTCCGGCTACTTCCCCCTCGGCGGCGTCATCGTGGGCGACAAGGTGGCGGAAGGCTTCATCGAGCATGGTGGCGACTTC
AACCACGGCTTCACCTATTCGGGCCATCCCGGCGGCTGCGCGGCGGCGCTGGCCAACCTTCGGATCATGCACGAGGAAAA
GCTGGTGGAGCGGGTGCGCACCGACATCGGGCCGTACCTGCAGGAGCGCTGGCTGAAGCTCGCCGAGCATCCCCTGGTGG
GCGAGGCGCGCATGGTGGGCCTCATCGGCGCGCTGGAGCTGACGCCGGAAAAGGCCTCCCGCGCGGCGTTCGCGGCGGAA
GAGGGGACGGTGGGCCTGATCTGCCGCGATTTCTCGTTCAGGGAAGGGCTGGTGATGCGCGCGGTGCGCGACGGCATGAT
CCTCGCCCCGCCCTTCACTTTGTCCCACGAGGAGGCCGACGAACTGGTGGCCATCACCTGGCGGGTGCTGGATCTCACCT
ACGCGGAACTGCATAAACGCGGGATGATGGTTCCGGTTCCGCGGGTTCCTGCGCGTCCGGTCCAAGCTTCGGCCTGA

Upstream 100 bases:

>100_bases
TCGCGATATGACTTTCCACATTGAGCACGCGCCGATCAGATTGAATCAACATGATCGGATCCGGCTCGGAGTTTCGCGGT
CCTCATCGGAGCAGCCCATC

Downstream 100 bases:

>100_bases
CCCGACTTAAGGACAGCCGCCAGTCTCGCGGTGGTGGGGCGACAAACATCAAGTTGTATCCCACCGCCGCGCTGCACTGG
ATTTACCACCATTACATAAA

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTSAPLSNSTAHWRALDAAHHLHPFSDTKALNAEGVRVITRAEGVYVFDSEGNRILDGMSGLWCSQVGHGRRAIVDAIAQ
QLHQLDYYNTFFKTTHPGAAELAAAISDVAPAHMNHVFFTSGGSEAVDTVLRMVRHYWAALGKPEKSIFISRRNGYHGST
LGGASLGGMKPMHAQGGLPIPGIIHVAQPYWWAEGGEMGREEFGLFAAREVARAIDEAGPENVAAFIGEPIQGAGGVIIP
PANYWPEVEKICRERDVLLVCDEVICGFGRTGRWFGADFMGVKPDLITFAKGITSGYFPLGGVIVGDKVAEGFIEHGGDF
NHGFTYSGHPGGCAAALANLRIMHEEKLVERVRTDIGPYLQERWLKLAEHPLVGEARMVGLIGALELTPEKASRAAFAAE
EGTVGLICRDFSFREGLVMRAVRDGMILAPPFTLSHEEADELVAITWRVLDLTYAELHKRGMMVPVPRVPARPVQASA

Sequences:

>Translated_478_residues
MTSAPLSNSTAHWRALDAAHHLHPFSDTKALNAEGVRVITRAEGVYVFDSEGNRILDGMSGLWCSQVGHGRRAIVDAIAQ
QLHQLDYYNTFFKTTHPGAAELAAAISDVAPAHMNHVFFTSGGSEAVDTVLRMVRHYWAALGKPEKSIFISRRNGYHGST
LGGASLGGMKPMHAQGGLPIPGIIHVAQPYWWAEGGEMGREEFGLFAAREVARAIDEAGPENVAAFIGEPIQGAGGVIIP
PANYWPEVEKICRERDVLLVCDEVICGFGRTGRWFGADFMGVKPDLITFAKGITSGYFPLGGVIVGDKVAEGFIEHGGDF
NHGFTYSGHPGGCAAALANLRIMHEEKLVERVRTDIGPYLQERWLKLAEHPLVGEARMVGLIGALELTPEKASRAAFAAE
EGTVGLICRDFSFREGLVMRAVRDGMILAPPFTLSHEEADELVAITWRVLDLTYAELHKRGMMVPVPRVPARPVQASA
>Mature_477_residues
TSAPLSNSTAHWRALDAAHHLHPFSDTKALNAEGVRVITRAEGVYVFDSEGNRILDGMSGLWCSQVGHGRRAIVDAIAQQ
LHQLDYYNTFFKTTHPGAAELAAAISDVAPAHMNHVFFTSGGSEAVDTVLRMVRHYWAALGKPEKSIFISRRNGYHGSTL
GGASLGGMKPMHAQGGLPIPGIIHVAQPYWWAEGGEMGREEFGLFAAREVARAIDEAGPENVAAFIGEPIQGAGGVIIPP
ANYWPEVEKICRERDVLLVCDEVICGFGRTGRWFGADFMGVKPDLITFAKGITSGYFPLGGVIVGDKVAEGFIEHGGDFN
HGFTYSGHPGGCAAALANLRIMHEEKLVERVRTDIGPYLQERWLKLAEHPLVGEARMVGLIGALELTPEKASRAAFAAEE
GTVGLICRDFSFREGLVMRAVRDGMILAPPFTLSHEEADELVAITWRVLDLTYAELHKRGMMVPVPRVPARPVQASA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=449, Percent_Identity=28.7305122494432, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226442705, Length=449, Percent_Identity=28.2850779510022, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=29.2857142857143, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI226442709, Length=421, Percent_Identity=28.2660332541568, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=30.1624129930394, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4557809, Length=436, Percent_Identity=27.9816513761468, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=33.0434782608696, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=29.5121951219512, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786991, Length=444, Percent_Identity=30.1801801801802, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789016, Length=355, Percent_Identity=32.6760563380282, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=28.009828009828, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=30.2955665024631, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=25.6281407035176, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=30.6122448979592, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=373, Percent_Identity=28.9544235924933, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=25.3012048192771, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=316, Percent_Identity=27.8481012658228, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=462, Percent_Identity=27.9220779220779, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=484, Percent_Identity=26.0330578512397, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=344, Percent_Identity=25.5813953488372, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=29.8076923076923, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI21357415, Length=436, Percent_Identity=27.0642201834862, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=28.6052009456265, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28574759, Length=378, Percent_Identity=29.3650793650794, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 51838; Mature: 51707

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAPLSNSTAHWRALDAAHHLHPFSDTKALNAEGVRVITRAEGVYVFDSEGNRILDGMS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEHHCCC
GLWCSQVGHGRRAIVDAIAQQLHQLDYYNTFFKTTHPGAAELAAAISDVAPAHMNHVFFT
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHCEEEEE
SGGSEAVDTVLRMVRHYWAALGKPEKSIFISRRNGYHGSTLGGASLGGMKPMHAQGGLPI
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGIIHVAQPYWWAEGGEMGREEFGLFAAREVARAIDEAGPENVAAFIGEPIQGAGGVIIP
CCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEC
PANYWPEVEKICRERDVLLVCDEVICGFGRTGRWFGADFMGVKPDLITFAKGITSGYFPL
CCCCCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GGVIVGDKVAEGFIEHGGDFNHGFTYSGHPGGCAAALANLRIMHEEKLVERVRTDIGPYL
CCEEECHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
QERWLKLAEHPLVGEARMVGLIGALELTPEKASRAAFAAEEGTVGLICRDFSFREGLVMR
HHHHHHHHCCCCCCCHHHHHHHHHEEECHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
AVRDGMILAPPFTLSHEEADELVAITWRVLDLTYAELHKRGMMVPVPRVPARPVQASA
HHHCCEEECCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TSAPLSNSTAHWRALDAAHHLHPFSDTKALNAEGVRVITRAEGVYVFDSEGNRILDGMS
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEHHCCC
GLWCSQVGHGRRAIVDAIAQQLHQLDYYNTFFKTTHPGAAELAAAISDVAPAHMNHVFFT
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHCEEEEE
SGGSEAVDTVLRMVRHYWAALGKPEKSIFISRRNGYHGSTLGGASLGGMKPMHAQGGLPI
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGIIHVAQPYWWAEGGEMGREEFGLFAAREVARAIDEAGPENVAAFIGEPIQGAGGVIIP
CCCEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEC
PANYWPEVEKICRERDVLLVCDEVICGFGRTGRWFGADFMGVKPDLITFAKGITSGYFPL
CCCCCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
GGVIVGDKVAEGFIEHGGDFNHGFTYSGHPGGCAAALANLRIMHEEKLVERVRTDIGPYL
CCEEECHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
QERWLKLAEHPLVGEARMVGLIGALELTPEKASRAAFAAEEGTVGLICRDFSFREGLVMR
HHHHHHHHCCCCCCCHHHHHHHHHEEECHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
AVRDGMILAPPFTLSHEEADELVAITWRVLDLTYAELHKRGMMVPVPRVPARPVQASA
HHHCCEEECCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]