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The map label for this gene is allR [H]

Identifier: 154246647

GI number: 154246647

Start: 2998974

End: 2999852

Strand: Direct

Name: allR [H]

Synonym: Xaut_2707

Alternate gene names: 154246647

Gene position: 2998974-2999852 (Clockwise)

Preceding gene: 154246636

Following gene: 154246653

Centisome position: 56.49

GC content: 67.35

Gene sequence:

>879_bases
ATGGACAAGAAACTCCCGCAAACCCCAGTCGAGAGCGACGCCGAGGCCAGCCCGAGCGGCCTTCTGGAACGGACCCTTGC
GGTGCTGGAGTTGCTGGCGGTCCATGCCCACGGCCTGCCGCTCTACGAGGTGGCCGACCATCTCCGCATTCCGCGCAGCG
CCACTCACCGCATCCTCAACAGCCTCGTGGAGCATGGATACGTGCGCCAGGAGCGTCAGCTCGGGGCCTATCTGCTCACG
GCCAAGCTGACCTCCCTGGCCTTCACTTTCCTTGCCGCCAGCGGCATCACCGACTTCGCCCAGCCCATTCTCGACCGCCT
CGCTCACCAATCCGGGGAGCTGGTGCGCCTCGCGATGATCGATGGCCGTGAGCTGATCTGGGTGGCGAAATCCCAGGGCT
CGCCCTTCGGGCTGCGCTATGACCCGGACATGGGGCAGGTGGGTCGCCTGTCCTGTTCGGCCTCCGGGCACGCCTGGCTA
TCGTGCCTGCCGGAAGAGGAGGCGATCGCTCTGGTGGAGACACAGGGCTATGGCGCGCGCCGCGACTTCGGTCCGCGGGC
GCCGGAAACCCGGACCGCGCTGTTGAAATATCTGCGCGTCGCCCGCAAGCGGGGCTTTGCCGTGACCGTGCAGACCTATA
CGCCGTGGATGAATGCCTGCGCCGCCCCAGTGCGCAGCATCGCCACCGGCGAAGTGACCGGAACGGTGGTGATCGCAGGG
CCTAATGTGCGTCTCACCGAGGCGCGTATGCTGGAGCTCGGGTCGCTGCTGATGGAAGCGGCGCGCGAGCTGTCCATGGC
AGTGAGCGCCTCCCCCGGCCTTTCCGCCCGGCGCGAGAGTGACCGATCGAGCTTCTTTGCGGGACCGGGCGAAGCCTGA

Upstream 100 bases:

>100_bases
GGCCCCTTCTGCCAAGACGTCGCTGCCCTCTGAAGTGGGTGCGGATCCCATCAAAGGCGGCCGGCAGCTCACCGTGCGGA
ATGGACAGCGTGACGAAGCC

Downstream 100 bases:

>100_bases
GCGGGGAGGGTGTCCGCTGAGACCGGCGAAATCGAGCGCCTTAGGGTCGAGACTCATGACCAGCCGCGATGCAGACGGCT
GCGAGGACGTTGACGGCGTT

Product: regulatory protein IclR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDKKLPQTPVESDAEASPSGLLERTLAVLELLAVHAHGLPLYEVADHLRIPRSATHRILNSLVEHGYVRQERQLGAYLLT
AKLTSLAFTFLAASGITDFAQPILDRLAHQSGELVRLAMIDGRELIWVAKSQGSPFGLRYDPDMGQVGRLSCSASGHAWL
SCLPEEEAIALVETQGYGARRDFGPRAPETRTALLKYLRVARKRGFAVTVQTYTPWMNACAAPVRSIATGEVTGTVVIAG
PNVRLTEARMLELGSLLMEAARELSMAVSASPGLSARRESDRSSFFAGPGEA

Sequences:

>Translated_292_residues
MDKKLPQTPVESDAEASPSGLLERTLAVLELLAVHAHGLPLYEVADHLRIPRSATHRILNSLVEHGYVRQERQLGAYLLT
AKLTSLAFTFLAASGITDFAQPILDRLAHQSGELVRLAMIDGRELIWVAKSQGSPFGLRYDPDMGQVGRLSCSASGHAWL
SCLPEEEAIALVETQGYGARRDFGPRAPETRTALLKYLRVARKRGFAVTVQTYTPWMNACAAPVRSIATGEVTGTVVIAG
PNVRLTEARMLELGSLLMEAARELSMAVSASPGLSARRESDRSSFFAGPGEA
>Mature_292_residues
MDKKLPQTPVESDAEASPSGLLERTLAVLELLAVHAHGLPLYEVADHLRIPRSATHRILNSLVEHGYVRQERQLGAYLLT
AKLTSLAFTFLAASGITDFAQPILDRLAHQSGELVRLAMIDGRELIWVAKSQGSPFGLRYDPDMGQVGRLSCSASGHAWL
SCLPEEEAIALVETQGYGARRDFGPRAPETRTALLKYLRVARKRGFAVTVQTYTPWMNACAAPVRSIATGEVTGTVVIAG
PNVRLTEARMLELGSLLMEAARELSMAVSASPGLSARRESDRSSFFAGPGEA

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=248, Percent_Identity=28.6290322580645, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=27.9352226720648, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786468, Length=250, Percent_Identity=25.6, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789999, Length=283, Percent_Identity=25.4416961130742, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31607; Mature: 31607

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKLPQTPVESDAEASPSGLLERTLAVLELLAVHAHGLPLYEVADHLRIPRSATHRILN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
SLVEHGYVRQERQLGAYLLTAKLTSLAFTFLAASGITDFAQPILDRLAHQSGELVRLAMI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEE
DGRELIWVAKSQGSPFGLRYDPDMGQVGRLSCSASGHAWLSCLPEEEAIALVETQGYGAR
CCCEEEEEEECCCCCCCEEECCCCCCCCCEEECCCCCEEEEECCCCCCEEEEEECCCCCC
RDFGPRAPETRTALLKYLRVARKRGFAVTVQTYTPWMNACAAPVRSIATGEVTGTVVIAG
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEC
PNVRLTEARMLELGSLLMEAARELSMAVSASPGLSARRESDRSSFFAGPGEA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDKKLPQTPVESDAEASPSGLLERTLAVLELLAVHAHGLPLYEVADHLRIPRSATHRILN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
SLVEHGYVRQERQLGAYLLTAKLTSLAFTFLAASGITDFAQPILDRLAHQSGELVRLAMI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEE
DGRELIWVAKSQGSPFGLRYDPDMGQVGRLSCSASGHAWLSCLPEEEAIALVETQGYGAR
CCCEEEEEEECCCCCCCEEECCCCCCCCCEEECCCCCEEEEECCCCCCEEEEEECCCCCC
RDFGPRAPETRTALLKYLRVARKRGFAVTVQTYTPWMNACAAPVRSIATGEVTGTVVIAG
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEC
PNVRLTEARMLELGSLLMEAARELSMAVSASPGLSARRESDRSSFFAGPGEA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA