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The map label for this gene is argJ [H]

Identifier: 154246525

GI number: 154246525

Start: 2874678

End: 2875919

Strand: Direct

Name: argJ [H]

Synonym: Xaut_2584

Alternate gene names: 154246525

Gene position: 2874678-2875919 (Clockwise)

Preceding gene: 154246524

Following gene: 154246526

Centisome position: 54.15

GC content: 68.92

Gene sequence:

>1242_bases
ATGTCGTCGACCATCTCTCCCCTCGCGCCCAAGTTCGTGCCCGAATTGCTGCCGGTGCCCGGGGTGAACTTCACCACCGC
CGCCGCCGGCATCCGCTATCACGGGCGCACCGATGTCCTGGTCATGTCGTTCGCGCCCGGCACCACGGTGGCCGGCGTCA
CCACAAGGTCCCTGTGCCCGTCCGCTCCGGTGGAGTGGTGCCGCGAGCTGCTGAAGAAGGGCAAGGCCCGCGCGCTGGTG
GTGAATTCCGGCAATGCCAACGCCTTTACTGGCCTGAAGGGCCGCGAGGCGACCCAGCTCACCGCCGAGATCGCCGCCGT
GGCGCTGGGCTGCAAGACCTCGGAGGTGTTCCTCGCCTCCACTGGCGTCATCGGCGAGCCGCTGGACGCCACCAAGTTCG
AGGGCGCGCTGACCGAGGCCGCCGGCCGCCTGGTGGACTGGCCGTGGCTCGACGCCGCCCGCGCCATCATGACCACGGAC
ACCTTCCCCAAGCTCGCCACCGCGCAGGTGCTGCTGGGCGACGTGCCGGTGACCATCAACGGCATCGCCAAGGGCGCCGG
CATGATCGCCCCTGACATGGCGACCATGCTCTCCTTCGTCTTCACCGATGCGCCCATCGCGGCCGGGGTGCTGCAGGACC
TGCTCTCCAAGGGTGTGAAGAACACCTTCAACGCCGTCACCATCGACGGCGACACCTCCACCTCCGACACCCTGCTGCTG
TTTGCCACCGGCGCCGCCAAGGCGCGGGGCGCGAAGACGGTGAAGAGCGTGGACGATCCGGCCCTGCGCGCCTTCCGCCA
CGCGCTGGTGGACCTACTCGCCGACCTTGCCGAGCAGGTGGCCCGCGACGGCGAGGGCGCCCGCAAGCTGCTACGCATCC
AGGTGACCGGGGCGGTATCGAAGAAGTCGGCGCGGCGCATCGCCATGTCCATCGCCAACTCGCCGCTGGTGAAGACCGCC
GTGGCCGGCGAGGATGCCAATTGGGGCCGCGTGGTGATGGCTGTGGGCAAGGCCGGCGAGCCGGCCGACCGCGACCGCCT
CACCATCGCCTTCGGCGACTATCGCGTCGCCCACGAAGGCGCCCGCGATCCCGATTACGACGAGGCCGTGGTCTCCCACT
ACATGAAGAACGACGTGATCGACCTGTTCGTGGACCTCGGCCTGGGCCGTGGCTCCGACCGGGTGCTCACCTGCGACCTC
ACCAAGGAATACGTGGCGATCAACGGGGATTATCGCTCGTGA

Upstream 100 bases:

>100_bases
GAAGGTCTGCCGCGGGGCTGCGGCAACCGGCGCCATCGGCGCGCTTGCCTTGCCCCTGAAGCTGCGGCACACGAGAGGCG
CCATCACCCGGGGAACAGCC

Downstream 100 bases:

>100_bases
GGGCGGGGGCGGCCCTGGCAGTGCTGATGGTGTTCGTCGCGGCCGCCTCTGCGGCTGGGGCGCAGTCGGCGGCGCGGGCC
GATGCGAGCGTACCACTAGC

Product: arginine biosynthesis bifunctional protein ArgJ

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSSTISPLAPKFVPELLPVPGVNFTTAAAGIRYHGRTDVLVMSFAPGTTVAGVTTRSLCPSAPVEWCRELLKKGKARALV
VNSGNANAFTGLKGREATQLTAEIAAVALGCKTSEVFLASTGVIGEPLDATKFEGALTEAAGRLVDWPWLDAARAIMTTD
TFPKLATAQVLLGDVPVTINGIAKGAGMIAPDMATMLSFVFTDAPIAAGVLQDLLSKGVKNTFNAVTIDGDTSTSDTLLL
FATGAAKARGAKTVKSVDDPALRAFRHALVDLLADLAEQVARDGEGARKLLRIQVTGAVSKKSARRIAMSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLTIAFGDYRVAHEGARDPDYDEAVVSHYMKNDVIDLFVDLGLGRGSDRVLTCDL
TKEYVAINGDYRS

Sequences:

>Translated_413_residues
MSSTISPLAPKFVPELLPVPGVNFTTAAAGIRYHGRTDVLVMSFAPGTTVAGVTTRSLCPSAPVEWCRELLKKGKARALV
VNSGNANAFTGLKGREATQLTAEIAAVALGCKTSEVFLASTGVIGEPLDATKFEGALTEAAGRLVDWPWLDAARAIMTTD
TFPKLATAQVLLGDVPVTINGIAKGAGMIAPDMATMLSFVFTDAPIAAGVLQDLLSKGVKNTFNAVTIDGDTSTSDTLLL
FATGAAKARGAKTVKSVDDPALRAFRHALVDLLADLAEQVARDGEGARKLLRIQVTGAVSKKSARRIAMSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLTIAFGDYRVAHEGARDPDYDEAVVSHYMKNDVIDLFVDLGLGRGSDRVLTCDL
TKEYVAINGDYRS
>Mature_412_residues
SSTISPLAPKFVPELLPVPGVNFTTAAAGIRYHGRTDVLVMSFAPGTTVAGVTTRSLCPSAPVEWCRELLKKGKARALVV
NSGNANAFTGLKGREATQLTAEIAAVALGCKTSEVFLASTGVIGEPLDATKFEGALTEAAGRLVDWPWLDAARAIMTTDT
FPKLATAQVLLGDVPVTINGIAKGAGMIAPDMATMLSFVFTDAPIAAGVLQDLLSKGVKNTFNAVTIDGDTSTSDTLLLF
ATGAAKARGAKTVKSVDDPALRAFRHALVDLLADLAEQVARDGEGARKLLRIQVTGAVSKKSARRIAMSIANSPLVKTAV
AGEDANWGRVVMAVGKAGEPADRDRLTIAFGDYRVAHEGARDPDYDEAVVSHYMKNDVIDLFVDLGLGRGSDRVLTCDLT
KEYVAINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=426, Percent_Identity=34.9765258215962, Blast_Score=234, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 43406; Mature: 43275

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTISPLAPKFVPELLPVPGVNFTTAAAGIRYHGRTDVLVMSFAPGTTVAGVTTRSLCP
CCCCCCCCCHHHHHHHCCCCCCCCCHHHCCEEECCCCCEEEEEECCCCEEECCCHHCCCC
SAPVEWCRELLKKGKARALVVNSGNANAFTGLKGREATQLTAEIAAVALGCKTSEVFLAS
CCHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
TGVIGEPLDATKFEGALTEAAGRLVDWPWLDAARAIMTTDTFPKLATAQVLLGDVPVTIN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEECCCCEEEE
GIAKGAGMIAPDMATMLSFVFTDAPIAAGVLQDLLSKGVKNTFNAVTIDGDTSTSDTLLL
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
FATGAAKARGAKTVKSVDDPALRAFRHALVDLLADLAEQVARDGEGARKLLRIQVTGAVS
EEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCC
KKSARRIAMSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLTIAFGDYRVAHEG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEECCC
ARDPDYDEAVVSHYMKNDVIDLFVDLGLGRGSDRVLTCDLTKEYVAINGDYRS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure 
SSTISPLAPKFVPELLPVPGVNFTTAAAGIRYHGRTDVLVMSFAPGTTVAGVTTRSLCP
CCCCCCCCHHHHHHHCCCCCCCCCHHHCCEEECCCCCEEEEEECCCCEEECCCHHCCCC
SAPVEWCRELLKKGKARALVVNSGNANAFTGLKGREATQLTAEIAAVALGCKTSEVFLAS
CCHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
TGVIGEPLDATKFEGALTEAAGRLVDWPWLDAARAIMTTDTFPKLATAQVLLGDVPVTIN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEECCCCEEEE
GIAKGAGMIAPDMATMLSFVFTDAPIAAGVLQDLLSKGVKNTFNAVTIDGDTSTSDTLLL
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
FATGAAKARGAKTVKSVDDPALRAFRHALVDLLADLAEQVARDGEGARKLLRIQVTGAVS
EEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCC
KKSARRIAMSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLTIAFGDYRVAHEG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEECCC
ARDPDYDEAVVSHYMKNDVIDLFVDLGLGRGSDRVLTCDLTKEYVAINGDYRS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]