Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 154246523

GI number: 154246523

Start: 2872890

End: 2874083

Strand: Direct

Name: argE [H]

Synonym: Xaut_2582

Alternate gene names: 154246523

Gene position: 2872890-2874083 (Clockwise)

Preceding gene: 154246521

Following gene: 154246524

Centisome position: 54.11

GC content: 69.85

Gene sequence:

>1194_bases
ATGAGCAGGCAAGTATCATCTGAAGAAATACTTGATAAACTCATCTCAATTTCTTCAATTACAGATACGCCCAATGAGGA
GGTGGTCGCCGCCATCGCGGCCATCGCCGCCCCCTTCGCCCGCGTGCGCCGCCTGCCCAACGCCGGCGGGGAGAAGACCG
CGCTGCTGATTTCCATCGGGCCGGAGGACCGCCCCGGCATCGTGCTCTCCGCCCACACCGATGTGGTGGCGGTGGAGGGG
CAGCCTTGGACCAGCAATCCCTTCCGCATCGCCGCGCGCGATGGCCGGCTTTACGGGCGCGGCACGTCCGACATGAAGGG
CTTCATCGCCTGTGTCCTCGCGGCGCTGCCCGCCTTCGCCGCCGCCGATCCGCTTACCCCCGTGCACGTTGCGCTTTCCT
ATGATGAGGAGATCGGCTGCAAGGGCGCGGGCGATCTCGTGGCGGCGGTGGCGGCCCTGCCGGCGCGCCCGCTCATGTGC
ATCGTCGGCGAGCCTACGGCCATGAAGGTGAAGCGCGCCCACAAGGGCAAGACCGGCTGGCGCGCCACGGCGCTGGGCCG
TACCGGCCATTCGGCCCTGCCGCACCAGGCGGCGAACGCGGTGACGGCGCTGGCCCGCCTCGCCGCCCGGCTCGCGGATC
TGGCGGACGAGTTGAAGACCGGCGCGCAGGACCGCGCCTTCGATCCGCCCTATGCCACGCTCCACATCGGCTCCCTCCAT
GGCGGCGGGGCGCTCAACGTGGTGCCGGACCGGGCGGTGATGGAATTCGAGCTGCGCACCATTCCCGGCAGCGACACCAA
CACCCTGTTCCGCCGCATCGAGGCGCTGGTGCAGGAGGCGCGCGCGGTCCTGAAGGCGCAAGCGCCCGAGGCCGATCTGC
TGCTGGAGGAGCTGTCCGCCTATCCCGCCCTCGCCACCGCCTCCGACGCGCCGGAGGCCGCTGCCGTGGCGCGGCTCACC
GGCGACAATGGCGTGCCGGGCACCATCGCCTTCGGCACCGAGGCCGGGCTCTATGCGCAGGCCGGCATTCCCACCCTCGT
CTGTGGCCCCGGCGACATCGCCCGCGCCCACAAGGCGGACGAATGGATCGGCCGCGAGGAGCTTGCCCAGTGCGATGCCA
TGCTGGCGAGACTCGCTGATATCATCCGCCGTCCGGCGGCCGACTGGATCAATGACCAACCGCGCCGCACCTGA

Upstream 100 bases:

>100_bases
GAGGTGATGGCGATGCCGAAGGCCCCGGTTTGCGGGCAGCGCGCGGCGATGGAATAGGTCATTCCCGTCTCCTTTTCATG
GAATTTCTAGCGAGGCGGCC

Downstream 100 bases:

>100_bases
GCCGGGACGCAAGACTGAGAGGCCGTTCATGTCGACAGAGAAAGCCGCCTTCACCCGTCCGGCCGCCCGCCTTACCCATG
CCGGCGCGCTGGTCGCGCTC

Product: acetylornithine deacetylase ArgE

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSRQVSSEEILDKLISISSITDTPNEEVVAAIAAIAAPFARVRRLPNAGGEKTALLISIGPEDRPGIVLSAHTDVVAVEG
QPWTSNPFRIAARDGRLYGRGTSDMKGFIACVLAALPAFAAADPLTPVHVALSYDEEIGCKGAGDLVAAVAALPARPLMC
IVGEPTAMKVKRAHKGKTGWRATALGRTGHSALPHQAANAVTALARLAARLADLADELKTGAQDRAFDPPYATLHIGSLH
GGGALNVVPDRAVMEFELRTIPGSDTNTLFRRIEALVQEARAVLKAQAPEADLLLEELSAYPALATASDAPEAAAVARLT
GDNGVPGTIAFGTEAGLYAQAGIPTLVCGPGDIARAHKADEWIGREELAQCDAMLARLADIIRRPAADWINDQPRRT

Sequences:

>Translated_397_residues
MSRQVSSEEILDKLISISSITDTPNEEVVAAIAAIAAPFARVRRLPNAGGEKTALLISIGPEDRPGIVLSAHTDVVAVEG
QPWTSNPFRIAARDGRLYGRGTSDMKGFIACVLAALPAFAAADPLTPVHVALSYDEEIGCKGAGDLVAAVAALPARPLMC
IVGEPTAMKVKRAHKGKTGWRATALGRTGHSALPHQAANAVTALARLAARLADLADELKTGAQDRAFDPPYATLHIGSLH
GGGALNVVPDRAVMEFELRTIPGSDTNTLFRRIEALVQEARAVLKAQAPEADLLLEELSAYPALATASDAPEAAAVARLT
GDNGVPGTIAFGTEAGLYAQAGIPTLVCGPGDIARAHKADEWIGREELAQCDAMLARLADIIRRPAADWINDQPRRT
>Mature_396_residues
SRQVSSEEILDKLISISSITDTPNEEVVAAIAAIAAPFARVRRLPNAGGEKTALLISIGPEDRPGIVLSAHTDVVAVEGQ
PWTSNPFRIAARDGRLYGRGTSDMKGFIACVLAALPAFAAADPLTPVHVALSYDEEIGCKGAGDLVAAVAALPARPLMCI
VGEPTAMKVKRAHKGKTGWRATALGRTGHSALPHQAANAVTALARLAARLADLADELKTGAQDRAFDPPYATLHIGSLHG
GGALNVVPDRAVMEFELRTIPGSDTNTLFRRIEALVQEARAVLKAQAPEADLLLEELSAYPALATASDAPEAAAVARLTG
DNGVPGTIAFGTEAGLYAQAGIPTLVCGPGDIARAHKADEWIGREELAQCDAMLARLADIIRRPAADWINDQPRRT

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=314, Percent_Identity=34.0764331210191, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788816, Length=204, Percent_Identity=31.8627450980392, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41618; Mature: 41487

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQVSSEEILDKLISISSITDTPNEEVVAAIAAIAAPFARVRRLPNAGGEKTALLISIG
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PEDRPGIVLSAHTDVVAVEGQPWTSNPFRIAARDGRLYGRGTSDMKGFIACVLAALPAFA
CCCCCCEEEEECCCEEEECCCCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHH
AADPLTPVHVALSYDEEIGCKGAGDLVAAVAALPARPLMCIVGEPTAMKVKRAHKGKTGW
HCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCC
RATALGRTGHSALPHQAANAVTALARLAARLADLADELKTGAQDRAFDPPYATLHIGSLH
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
GGGALNVVPDRAVMEFELRTIPGSDTNTLFRRIEALVQEARAVLKAQAPEADLLLEELSA
CCCEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
YPALATASDAPEAAAVARLTGDNGVPGTIAFGTEAGLYAQAGIPTLVCGPGDIARAHKAD
CCCCCCCCCCCCHHHEEEECCCCCCCCEEEECCCCCEEEECCCCEEEECCCHHHHHHHHH
EWIGREELAQCDAMLARLADIIRRPAADWINDQPRRT
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
SRQVSSEEILDKLISISSITDTPNEEVVAAIAAIAAPFARVRRLPNAGGEKTALLISIG
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PEDRPGIVLSAHTDVVAVEGQPWTSNPFRIAARDGRLYGRGTSDMKGFIACVLAALPAFA
CCCCCCEEEEECCCEEEECCCCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHH
AADPLTPVHVALSYDEEIGCKGAGDLVAAVAALPARPLMCIVGEPTAMKVKRAHKGKTGW
HCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCC
RATALGRTGHSALPHQAANAVTALARLAARLADLADELKTGAQDRAFDPPYATLHIGSLH
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
GGGALNVVPDRAVMEFELRTIPGSDTNTLFRRIEALVQEARAVLKAQAPEADLLLEELSA
CCCEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
YPALATASDAPEAAAVARLTGDNGVPGTIAFGTEAGLYAQAGIPTLVCGPGDIARAHKAD
CCCCCCCCCCCCHHHEEEECCCCCCCCEEEECCCCCEEEECCCCEEEECCCHHHHHHHHH
EWIGREELAQCDAMLARLADIIRRPAADWINDQPRRT
HHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]