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The map label for this gene is efp

Identifier: 154246472

GI number: 154246472

Start: 2828637

End: 2829206

Strand: Direct

Name: efp

Synonym: Xaut_2531

Alternate gene names: 154246472

Gene position: 2828637-2829206 (Clockwise)

Preceding gene: 154246470

Following gene: 154246473

Centisome position: 53.28

GC content: 61.75

Gene sequence:

>570_bases
GTGGTCAAGGTCATCGCCAGCTCTCTGCGCAAAGGCAATGTGGTCGATATCGACGACAAGCTCTATGTGGTGCTCACCGC
TGAAAATATTCATCCCGGCAAGGGCACGCCGGTCACCCAGCTCGACATGCGCCGCATCTCCGACGGGGTGAAGATCTCCG
AGCGCTACCGCACCACCGAGCAGGTGGAGCGCGCCTTCGTGGAAGACCGCCCGCACACTTTCCTCTACGAGGATTCGGAC
GGCTACACCTTCATGAACCCTGAGAATTTCGATCAGGTGATCGTGACCAAGGACGTGATGGGCGACTCGGCGGTGTATCT
GCAGGAAGGCATGGAATGCATGCTCTCCACCCATAACGGCGTTCCCATCGCCATCGAGCTGCCGGCGCGCGTGACGCTGG
AGATCGTGGACACCGAGCCCACCGTGAAGGGCCAGACCGCCTCGTCCTCCTACAAGCCGGCCAAGCTTTCCAATGGCGTG
CGCACCATGGTGCCGCCGCACATCTCCGCGGGCACCCGCGTGGTGATCATGACCGCCGACAACTCCTATGTGGAGCGGGC
CAAGGACTGA

Upstream 100 bases:

>100_bases
AGGCGGGCACGAGACTGGTTTTGTGCGCCAAGATCGCTATGTTGCGCGCCGATAGATCAGGAGCGGCACGCCGCCGCACA
AAGTTCAAGGAAGACGCGAC

Downstream 100 bases:

>100_bases
CCGGCAGGCTGACCCCGGGACGGTCCCGCTGGGACCGTCCTGCTCGGGTCCGCCCGCTTGGCGGCCTCTCGCGCTCCGTC
TCGTCGCCCTGGTGCGTCGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVKVIASSLRKGNVVDIDDKLYVVLTAENIHPGKGTPVTQLDMRRISDGVKISERYRTTEQVERAFVEDRPHTFLYEDSD
GYTFMNPENFDQVIVTKDVMGDSAVYLQEGMECMLSTHNGVPIAIELPARVTLEIVDTEPTVKGQTASSSYKPAKLSNGV
RTMVPPHISAGTRVVIMTADNSYVERAKD

Sequences:

>Translated_189_residues
MVKVIASSLRKGNVVDIDDKLYVVLTAENIHPGKGTPVTQLDMRRISDGVKISERYRTTEQVERAFVEDRPHTFLYEDSD
GYTFMNPENFDQVIVTKDVMGDSAVYLQEGMECMLSTHNGVPIAIELPARVTLEIVDTEPTVKGQTASSSYKPAKLSNGV
RTMVPPHISAGTRVVIMTADNSYVERAKD
>Mature_189_residues
MVKVIASSLRKGNVVDIDDKLYVVLTAENIHPGKGTPVTQLDMRRISDGVKISERYRTTEQVERAFVEDRPHTFLYEDSD
GYTFMNPENFDQVIVTKDVMGDSAVYLQEGMECMLSTHNGVPIAIELPARVTLEIVDTEPTVKGQTASSSYKPAKLSNGV
RTMVPPHISAGTRVVIMTADNSYVERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=35.1063829787234, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=32.258064516129, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_XANP2 (A7IID0)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417430.1
- ProteinModelPortal:   A7IID0
- SMR:   A7IID0
- STRING:   A7IID0
- GeneID:   5425137
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2531
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   VVIMTAD
- ProtClustDB:   PRK00529
- BioCyc:   XAUT78245:XAUT_2531-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20966; Mature: 20966

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVIASSLRKGNVVDIDDKLYVVLTAENIHPGKGTPVTQLDMRRISDGVKISERYRTTE
CCEEEEHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEHHHHCCHH
QVERAFVEDRPHTFLYEDSDGYTFMNPENFDQVIVTKDVMGDSAVYLQEGMECMLSTHNG
HHHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHEEEECCCC
VPIAIELPARVTLEIVDTEPTVKGQTASSSYKPAKLSNGVRTMVPPHISAGTRVVIMTAD
CEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEECC
NSYVERAKD
CHHHHCCCC
>Mature Secondary Structure
MVKVIASSLRKGNVVDIDDKLYVVLTAENIHPGKGTPVTQLDMRRISDGVKISERYRTTE
CCEEEEHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEHHHHCCHH
QVERAFVEDRPHTFLYEDSDGYTFMNPENFDQVIVTKDVMGDSAVYLQEGMECMLSTHNG
HHHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHEEEECCCC
VPIAIELPARVTLEIVDTEPTVKGQTASSSYKPAKLSNGVRTMVPPHISAGTRVVIMTAD
CEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEECC
NSYVERAKD
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA