Definition Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession NC_009720
Length 5,308,934

Click here to switch to the map view.

The map label for this gene is ucpA [H]

Identifier: 154245939

GI number: 154245939

Start: 2252394

End: 2253137

Strand: Reverse

Name: ucpA [H]

Synonym: Xaut_1996

Alternate gene names: 154245939

Gene position: 2253137-2252394 (Counterclockwise)

Preceding gene: 154245940

Following gene: 154245938

Centisome position: 42.44

GC content: 68.68

Gene sequence:

>744_bases
ATGGCTGGACGACTTCAGGGTAAGACCGCGCTGGTGACGGCGGCGGGACAGGGCATCGGCCGGGCCATCGCCGAGGCCTT
CGTGCGCGAGGGCGCGAGCGTGATCGCCACCGACCTCGACACCGCCAAGCTCGAAGGCTTTCCCGGCACCGCCCGCAAGC
TCGACGTGCGCTCCAGCGAGGCCGTCGCCGCGCTGGCGAAGGAGATCGGCCCGGTGGACGTGCTGGTGAATGCCGCTGGC
TACGTCCACCAGGGCAATATCTTCGACACTTCGGAGAAGGACTGGGACTTCTCCTTCGACCTCAATGTGAAGGCCATGCA
CCGCACCATCTCGGCCTTCCTGCCGGGCATGCTGGAGAAGGGCAAAGGCTCCATCGTCAACATCGCCTCGGCGGCGTCCT
CCATCCGCGGCGTGCCGAACCGCTATGTCTACGGCGCCTCCAAGGCGGCGGTCATCGGCCTCACCAAGGCAGTGGCGGCG
GACTTCATCCTGAAGGGCGTTCGCGCCAACGTCATCTGCCCCGGCACCATCCAGTCGCCCTCGCTGGACGAGCGCATCGC
CGCCGTCTCGGCCCAGACCGGCCGCTCGCTGGACGACGTGCGGGCCGATTTCGTCGGCCGCCAGCCCATGGGCCGGCTCG
GCACGCCGGAGGAGATCGCGGCGCTCGCGCTCTATCTCGCCTCCGACGAGAGCGCCTTCACCACCGGGCAGATCCACATC
ATCGACGGCGGCTGGGCGCTCTAG

Upstream 100 bases:

>100_bases
CAATTTCGACGCCGAAGGCCGCCAGACGCAGCGGCTGGAGGACATCCGCGCCGCATTGTGAGGCATCGCCTCACCCATCC
AAAAGCTCAAGAGGAACGCC

Downstream 100 bases:

>100_bases
GGCGCCCGCCGGGACGGCCTTGCCACAGGATCATCGAAAGATCGCGCCTTCGGCTCGCATCGGGGCGCCTTAAGGGAAGA
AACCTGACATGCATATTCTC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAGRLQGKTALVTAAGQGIGRAIAEAFVREGASVIATDLDTAKLEGFPGTARKLDVRSSEAVAALAKEIGPVDVLVNAAG
YVHQGNIFDTSEKDWDFSFDLNVKAMHRTISAFLPGMLEKGKGSIVNIASAASSIRGVPNRYVYGASKAAVIGLTKAVAA
DFILKGVRANVICPGTIQSPSLDERIAAVSAQTGRSLDDVRADFVGRQPMGRLGTPEEIAALALYLASDESAFTTGQIHI
IDGGWAL

Sequences:

>Translated_247_residues
MAGRLQGKTALVTAAGQGIGRAIAEAFVREGASVIATDLDTAKLEGFPGTARKLDVRSSEAVAALAKEIGPVDVLVNAAG
YVHQGNIFDTSEKDWDFSFDLNVKAMHRTISAFLPGMLEKGKGSIVNIASAASSIRGVPNRYVYGASKAAVIGLTKAVAA
DFILKGVRANVICPGTIQSPSLDERIAAVSAQTGRSLDDVRADFVGRQPMGRLGTPEEIAALALYLASDESAFTTGQIHI
IDGGWAL
>Mature_246_residues
AGRLQGKTALVTAAGQGIGRAIAEAFVREGASVIATDLDTAKLEGFPGTARKLDVRSSEAVAALAKEIGPVDVLVNAAGY
VHQGNIFDTSEKDWDFSFDLNVKAMHRTISAFLPGMLEKGKGSIVNIASAASSIRGVPNRYVYGASKAAVIGLTKAVAAD
FILKGVRANVICPGTIQSPSLDERIAAVSAQTGRSLDDVRADFVGRQPMGRLGTPEEIAALALYLASDESAFTTGQIHII
DGGWAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=54.6184738955823, Blast_Score=257, Evalue=7e-69,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=32.7067669172932, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.8897637795276, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=30.5220883534137, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=29.2490118577075, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=28.5171102661597, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=33.1632653061224, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI40807363, Length=190, Percent_Identity=32.6315789473684, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.8936170212766, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI210032110, Length=214, Percent_Identity=26.1682242990654, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=30.9160305343511, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=30.1507537688442, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI210032112, Length=201, Percent_Identity=25.3731343283582, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=32.9842931937173, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=33.5164835164835, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4504505, Length=261, Percent_Identity=28.3524904214559, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4758504, Length=266, Percent_Identity=29.3233082706767, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310128830, Length=199, Percent_Identity=29.1457286432161, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI310115468, Length=199, Percent_Identity=29.1457286432161, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=39.2996108949416, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=32.2834645669291, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=30.1960784313725, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=32.6771653543307, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=30.9160305343511, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=29.4573643410853, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.6451612903226, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=32.7868852459016, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.5275590551181, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=23.8461538461538, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=30, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=33.0739299610895, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=31.4393939393939, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=32.5490196078431, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=30.6201550387597, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=32.3076923076923, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=30.4182509505703, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=30.078125, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=30.7407407407407, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=30.5147058823529, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=31.6546762589928, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=28.6245353159851, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=28.1954887218045, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.8507462686567, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=29.5620437956204, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=33.5051546391753, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.515625, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=27.8195488721804, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=30.8900523560209, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=29.3478260869565, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=28.2527881040892, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=27.6119402985075, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=32.089552238806, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=31.8352059925094, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=29.9638989169675, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=27.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=264, Percent_Identity=32.5757575757576, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=223, Percent_Identity=26.457399103139, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=27.2030651340996, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=29.4416243654822, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=34.6303501945525, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.5731225296443, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=33.969465648855, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=31.3492063492063, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=32.6848249027237, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.9212598425197, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=33.5294117647059, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=30.5019305019305, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=31.0526315789474, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=31.3432835820896, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640492, Length=180, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=26.0416666666667, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=25.6281407035176, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25729; Mature: 25597

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAGRLQGKTALVTAAGQGIGRAIAEAFVREGASVIATDLDTAKLEGFPGTARKLDVRSSE
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCEEEECCCHH
AVAALAKEIGPVDVLVNAAGYVHQGNIFDTSEKDWDFSFDLNVKAMHRTISAFLPGMLEK
HHHHHHHHCCCCEEEEECCCEEEECCEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
GKGSIVNIASAASSIRGVPNRYVYGASKAAVIGLTKAVAADFILKGVRANVICPGTIQSP
CCCCEEEHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
SLDERIAAVSAQTGRSLDDVRADFVGRQPMGRLGTPEEIAALALYLASDESAFTTGQIHI
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCCEEECEEEE
IDGGWAL
ECCCCCC
>Mature Secondary Structure 
AGRLQGKTALVTAAGQGIGRAIAEAFVREGASVIATDLDTAKLEGFPGTARKLDVRSSE
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCEEEECCCHH
AVAALAKEIGPVDVLVNAAGYVHQGNIFDTSEKDWDFSFDLNVKAMHRTISAFLPGMLEK
HHHHHHHHCCCCEEEEECCCEEEECCEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
GKGSIVNIASAASSIRGVPNRYVYGASKAAVIGLTKAVAADFILKGVRANVICPGTIQSP
CCCCEEEHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
SLDERIAAVSAQTGRSLDDVRADFVGRQPMGRLGTPEEIAALALYLASDESAFTTGQIHI
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCCEEECEEEE
IDGGWAL
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]