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The map label for this gene is fbp1

Identifier: 154245859

GI number: 154245859

Start: 2166514

End: 2167629

Strand: Reverse

Name: fbp1

Synonym: Xaut_1915

Alternate gene names: 154245859

Gene position: 2167629-2166514 (Counterclockwise)

Preceding gene: 154245860

Following gene: 154245858

Centisome position: 40.83

GC content: 69.62

Gene sequence:

>1116_bases
ATGACGACCCGCCGAACGGGTCGCGCGGAGAAGACCCTCAGGGAGACGACCGCCATGCCAACCGCCGATCATCGCGCCGC
ACCCGGAATCACGCTTGCCTGCGCGCTCGAGGAATGGGCGGGCGAGGACGCCCGCCGCCGCGATGTCGCCGCGACCCTCA
ACGCGCTCGCCGCAGGCACCATCCAGATCGCCCGCGCCATTGCCGAGGGTCCGCTCGCCGGCGACCTCGCACGCACCCTC
TCGTCCGGTGAAGCGGGCGAGGGCCAGAAGGCGCTCGACATCATCTCCAACGACATGGTCATCGACGCCCTGCGCAAGGC
CCCGGTGGCCGCCGTCGCCTCGGAGGAGAACGACGCGCCGGTGCTGCTTGATCCCGAAGCCCCGCTGCTGGTGGCCATCG
ACCCGCTGGACGGCTCGTCCAACATCGACACCGACATCTCGGTGGGCACCATCTTCGCCGTGTTCCCGCACCAGGACGGC
ACCGACGCGGCAAGCGTCACCGCCTTCCTGCAGAACGGGCGCGACATGCTCGCCGGCGGCTATGTCATCTACGGGCCTCA
CACCGCGCTGATGCTCACGGTGGGCGCCGGCACCTGGCACTTTGCCCTCGACCGGGACGGCTCCTTCCGCCTCGTGAACG
CGGCGGTGCGGGTGAAGGAAGACGCCGCCGAGTTCGCCATCAACATGTCGAACTACCACCACTGGGACGATCCGATCCGC
GCCTATGTGGACGATTGCCTGGCCGGCAGGAAGGGCCCGCGCGAGCGCGAGTTCAACATGCGCTGGGTGGCGTCAATGGT
CGCGGATGCGCACCGCATCTTCCAGCGCGGCGGCATCTATCTTTATCCCGGCGACGGCCGCAAGGGCTACACCCACGGCC
GCCTGCGCCTGCTCTACGAAGCCTTCCCCGTCGCCTTCCTGATGGAACAGGCCCAGGGCTCGGCCATCGACGGGCGCAGT
TCCATCCTCGACCTCTCGGCCACCGGCGTGCACCAGCGCGTGCCCTTCATCTTCGGCTCGCGCGACGAGGTGGCCCGCGC
CGCCCGCTATCACCTGGAGCCCTCGGGCCACGGCGAGCGCTCACCGCTGTTCGCGCGGCGCGGCCTGTTCATCTGA

Upstream 100 bases:

>100_bases
ACCGAAGGCGACGTGCGCGCCAGCCGTGTGTTCTCGGGGGGCATCGACGCCCCCGACTACAAGCCCCGCAACGCATAAGG
CTGCGGGACCAAAAACACCG

Downstream 100 bases:

>100_bases
TCCCGGCAGCCAAGACAAAAGAAGAGCCGAGCACTCCATGTCCATCAAGCATCCCATCATCGTCGTCACCGGTTCGTCGG
GCGCCGGGACGACCTCCGTG

Product: inositol phosphatase/fructose-16-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTTRRTGRAEKTLRETTAMPTADHRAAPGITLACALEEWAGEDARRRDVAATLNALAAGTIQIARAIAEGPLAGDLARTL
SSGEAGEGQKALDIISNDMVIDALRKAPVAAVASEENDAPVLLDPEAPLLVAIDPLDGSSNIDTDISVGTIFAVFPHQDG
TDAASVTAFLQNGRDMLAGGYVIYGPHTALMLTVGAGTWHFALDRDGSFRLVNAAVRVKEDAAEFAINMSNYHHWDDPIR
AYVDDCLAGRKGPREREFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYEAFPVAFLMEQAQGSAIDGRS
SILDLSATGVHQRVPFIFGSRDEVARAARYHLEPSGHGERSPLFARRGLFI

Sequences:

>Translated_371_residues
MTTRRTGRAEKTLRETTAMPTADHRAAPGITLACALEEWAGEDARRRDVAATLNALAAGTIQIARAIAEGPLAGDLARTL
SSGEAGEGQKALDIISNDMVIDALRKAPVAAVASEENDAPVLLDPEAPLLVAIDPLDGSSNIDTDISVGTIFAVFPHQDG
TDAASVTAFLQNGRDMLAGGYVIYGPHTALMLTVGAGTWHFALDRDGSFRLVNAAVRVKEDAAEFAINMSNYHHWDDPIR
AYVDDCLAGRKGPREREFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYEAFPVAFLMEQAQGSAIDGRS
SILDLSATGVHQRVPFIFGSRDEVARAARYHLEPSGHGERSPLFARRGLFI
>Mature_370_residues
TTRRTGRAEKTLRETTAMPTADHRAAPGITLACALEEWAGEDARRRDVAATLNALAAGTIQIARAIAEGPLAGDLARTLS
SGEAGEGQKALDIISNDMVIDALRKAPVAAVASEENDAPVLLDPEAPLLVAIDPLDGSSNIDTDISVGTIFAVFPHQDGT
DAASVTAFLQNGRDMLAGGYVIYGPHTALMLTVGAGTWHFALDRDGSFRLVNAAVRVKEDAAEFAINMSNYHHWDDPIRA
YVDDCLAGRKGPREREFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYEAFPVAFLMEQAQGSAIDGRSS
ILDLSATGVHQRVPFIFGSRDEVARAARYHLEPSGHGERSPLFARRGLFI

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=328, Percent_Identity=35.9756097560976, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI16579888, Length=328, Percent_Identity=35.9756097560976, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI22907028, Length=303, Percent_Identity=35.973597359736, Blast_Score=171, Evalue=8e-43,
Organism=Escherichia coli, GI1790679, Length=309, Percent_Identity=37.8640776699029, Blast_Score=188, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508131, Length=331, Percent_Identity=34.7432024169184, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323409, Length=306, Percent_Identity=35.9477124183007, Blast_Score=186, Evalue=6e-48,
Organism=Drosophila melanogaster, GI45550998, Length=271, Percent_Identity=38.3763837638376, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19921562, Length=271, Percent_Identity=38.3763837638376, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16A1_XANP2 (A7IGL7)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416817.1
- ProteinModelPortal:   A7IGL7
- SMR:   A7IGL7
- STRING:   A7IGL7
- GeneID:   5424513
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_1915
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   PVAFLME
- BioCyc:   XAUT78245:XAUT_1915-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 40095; Mature: 39963

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00124 FBPASE

Important sites: BINDING 228-228

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRRTGRAEKTLRETTAMPTADHRAAPGITLACALEEWAGEDARRRDVAATLNALAAGT
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHH
IQIARAIAEGPLAGDLARTLSSGEAGEGQKALDIISNDMVIDALRKAPVAAVASEENDAP
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHCCEEEEECCCCCCC
VLLDPEAPLLVAIDPLDGSSNIDTDISVGTIFAVFPHQDGTDAASVTAFLQNGRDMLAGG
EEECCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECC
YVIYGPHTALMLTVGAGTWHFALDRDGSFRLVNAAVRVKEDAAEFAINMSNYHHWDDPIR
EEEECCCEEEEEEECCCEEEEEECCCCCEEEEEEEHHHHHHHHHHEEECCCCCCCCHHHH
AYVDDCLAGRKGPREREFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
AFPVAFLMEQAQGSAIDGRSSILDLSATGVHQRVPFIFGSRDEVARAARYHLEPSGHGER
HHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCEEECCHHHHHHHHHHCCCCCCCCCC
SPLFARRGLFI
CCHHHHCCCCC
>Mature Secondary Structure 
TTRRTGRAEKTLRETTAMPTADHRAAPGITLACALEEWAGEDARRRDVAATLNALAAGT
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHH
IQIARAIAEGPLAGDLARTLSSGEAGEGQKALDIISNDMVIDALRKAPVAAVASEENDAP
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHCCEEEEECCCCCCC
VLLDPEAPLLVAIDPLDGSSNIDTDISVGTIFAVFPHQDGTDAASVTAFLQNGRDMLAGG
EEECCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECC
YVIYGPHTALMLTVGAGTWHFALDRDGSFRLVNAAVRVKEDAAEFAINMSNYHHWDDPIR
EEEECCCEEEEEEECCCEEEEEECCCCCEEEEEEEHHHHHHHHHHEEECCCCCCCCHHHH
AYVDDCLAGRKGPREREFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
AFPVAFLMEQAQGSAIDGRSSILDLSATGVHQRVPFIFGSRDEVARAARYHLEPSGHGER
HHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCEEECCHHHHHHHHHHCCCCCCCCCC
SPLFARRGLFI
CCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA