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The map label for this gene is mraY

Identifier: 154245791

GI number: 154245791

Start: 2077750

End: 2078835

Strand: Reverse

Name: mraY

Synonym: Xaut_1847

Alternate gene names: 154245791

Gene position: 2078835-2077750 (Counterclockwise)

Preceding gene: 154245792

Following gene: 154245789

Centisome position: 39.16

GC content: 66.02

Gene sequence:

>1086_bases
ATGCTCCAGTGGCTTGCCGAATTCCACGCGTCGTTCCCCGCCTTCAACGTGTTCCGCTACATCACCTTTCGCACCGGCGG
GGCGGTGGTGACGGCACTGTTGTTCGTGTTCCTGTTCGGGCCGGGCATGATCTCCACGCTCCGCCTGAAGCAGGGCAAGG
GCCAGCCCATCCGCACCGACGGGCCGCAGTCGCACCTGCTCACCAAGAAGGGCACGCCCACCATGGGCGGGCTCATGATC
CTGTCGGGCATCGTGGTCGCCACCCTGCTGTGGGCGAACCTCTCCAACCCCTATGTCTGGGTGGTGCTGGGGGTGACGCT
GGGCTTCGGCCTCATCGGCTTCTACGACGACTATCTGAAGGTGACCAAGCAAACCCACAATGGCCTGTCCGGCAAGGCGC
GCCTCGCCATCGAGGCGGTGATCGCCGGGGTCGCGGTGGTCATCGTCATGAGCGTCGGCAAGCCGGGGCTGTCCACCTCG
GTGGCCTTCCCCTTCTTCAAGGACCTGCTGCTCAACCTCGGCATGTTCTTCGCCATCTTCGGCATGTTCGTCATCGTGGC
GGCGGGCAATGCGGTGAACCTCACCGACGGGCTCGACGGCCTCGCCATCGTGCCGGTGATGATCGCGGCGGGCTCGTTCG
GCTTCATCGCCTATCTCGCCGGCAACGTGGTGTTCGCCGACTATCTGCAGATCCACTATGTGGCCGGCGTCGGCGAGCTG
GCGGTGATCTGCGGGGCGCTGATGGGGGCGGGCCTCGGCTTCCTGTGGTTCAACGCGCCGCCGGCCCAGGTGTTCATGGG
CGACACCGGCTCGCTCGCCCTGGGCGGCCTGCTCGGCACGGTGGCGGTGGCGACCAAGCACGAGATCGTGCTGGCGGTCA
TCGGCGGCCTGTTCGTGCTGGAGGCGGTGTCGGTGATCGTGCAGGTGGTGTCGTTCAAGCTCACCGGCAAGCGGGTGTTC
AAGATGGCGCCCATCCACCATCATTTCGAGCAGCTCGGCTGGACCGAGCCGCAGGTGGTAATCCGCTTCTGGATCGTCGC
CGTGGTACTGGCGCTGGCGGGCCTCGCGACATTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
GTGAAGGGATCCAACGGCAGCCGCATGGGACCCTTGGTCAAGAAGCTCGCCGAGCGCTTCCGCGCCGGCGAGGACGCGCT
GCTCGAAGGATAATTTTTCA

Downstream 100 bases:

>100_bases
GGGGCGGCTCAATCCGACGAAAAAAGGCCCGCGGGATACTCTCCCCGGGCCTTTTCATGCTTGGAGGCCTGAAAGCCTCA
CTCCCGCTCGCAGGTCCTGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTDGPQSHLLTKKGTPTMGGLMI
LSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLKVTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTS
VAFPFFKDLLLNLGMFFAIFGMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGEL
AVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVLEAVSVIVQVVSFKLTGKRVF
KMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKLR

Sequences:

>Translated_361_residues
MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTDGPQSHLLTKKGTPTMGGLMI
LSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLKVTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTS
VAFPFFKDLLLNLGMFFAIFGMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGEL
AVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVLEAVSVIVQVVSFKLTGKRVF
KMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKLR
>Mature_361_residues
MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTDGPQSHLLTKKGTPTMGGLMI
LSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLKVTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTS
VAFPFFKDLLLNLGMFFAIFGMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGEL
AVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVLEAVSVIVQVVSFKLTGKRVF
KMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=363, Percent_Identity=54.2699724517906, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_XANP2 (A7IGE9)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416749.1
- STRING:   A7IGE9
- GeneID:   5423628
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_1847
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   XAUT78245:XAUT_1847-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38300; Mature: 38300

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe4728d4)-; HASH(0x10cbb120)-; HASH(0x100fddc0)-; HASH(0x10cbb354)-; HASH(0x1050f810)-; HASH(0x10cdf164)-; HASH(0x10cdcf58)-; HASH(0x1087ca90)-; HASH(0x10ca23dc)-; HASH(0x104e0750)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTD
CHHHHHHHHCCCCHHHHHHHEEEECCHHHHHHHHHHHHHCCCHHHHHEECCCCCCCCCCC
GPQSHLLTKKGTPTMGGLMILSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLK
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHH
VTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTSVAFPFFKDLLLNLGMFFAIF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGEL
HHHHHHHCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHH
AVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVL
HHHHHHHHHCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVSVIVQVVSFKLTGKRVFKMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKL
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHEEC
R
H
>Mature Secondary Structure
MLQWLAEFHASFPAFNVFRYITFRTGGAVVTALLFVFLFGPGMISTLRLKQGKGQPIRTD
CHHHHHHHHCCCCHHHHHHHEEEECCHHHHHHHHHHHHHCCCHHHHHEECCCCCCCCCCC
GPQSHLLTKKGTPTMGGLMILSGIVVATLLWANLSNPYVWVVLGVTLGFGLIGFYDDYLK
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHH
VTKQTHNGLSGKARLAIEAVIAGVAVVIVMSVGKPGLSTSVAFPFFKDLLLNLGMFFAIF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GMFVIVAAGNAVNLTDGLDGLAIVPVMIAAGSFGFIAYLAGNVVFADYLQIHYVAGVGEL
HHHHHHHCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHH
AVICGALMGAGLGFLWFNAPPAQVFMGDTGSLALGGLLGTVAVATKHEIVLAVIGGLFVL
HHHHHHHHHCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVSVIVQVVSFKLTGKRVFKMAPIHHHFEQLGWTEPQVVIRFWIVAVVLALAGLATLKL
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHEEC
R
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA