Click here to switch to the map view.

The map label for this gene is yycF [H]

Identifier: 154245715

GI number: 154245715

Start: 1996252

End: 1996938

Strand: Direct

Name: yycF [H]

Synonym: Xaut_1771

Alternate gene names: 154245715

Gene position: 1996252-1996938 (Clockwise)

Preceding gene: 154245710

Following gene: 154245716

Centisome position: 37.6

GC content: 66.38

Gene sequence:

>687_bases
ATGCCCAATGCGTGGAAAATCCTGGTGGTCGAAGACGACCCGGAGCTGCGCGACGCCCTGATCGAACAGCTCGCGCTCCA
GGACGAGTTCGAACCGGTGCCCGCCGAGACCGCCGCCGGCGCCATGGAACTGGCGAAGAACGGCGCCATCGATCTCGTCA
TCATGGATGTGGGCCTGCCCGACATGGACGGGCGCGAGGCGGTGCGCCTGATGCGGCGCTCGGGCTTCAAGGCGCCCATT
CTCATGCTCACCGGGCACGACACCGACAGCGACACCATCCTGGGCCTCGAGGCCGGGGCCAACGACTATATCATCAAACC
GTTCCGCTTCGCCGTGCTGCTGGCGCGCCTGCGAGCGCAGATGCGCTCCCACGAGGCGAGCGAAGACGCGGTGTTCGCCA
TCGGCCCCTATTCCTTCCGGCCCGGCGCCAAGCTGCTGCTGACCGATCGCGGCTCCAAGATCCGCCTGACCGAGAAGGAG
ACGGCGATCCTGCGCTATCTCTACCGCGCCGGGAAGACGCCGGTGCCCCGCGAGACCCTGCTGCAGGAAGTGTGGGGTTA
TAATTCCGGGGTCACCACCCATACTCTGGAAACCCACATCTACCGCCTGCGCCAGAAGATCGAGCCCGATCCCTCCAACC
CCACCCTGCTCGCAACCCAGGCCGGCGGCTACAAGCTGGTGCCCTGA

Upstream 100 bases:

>100_bases
ATACCCCCCGACGCCCGTCCATGGATGGAAATTTGCGTCAAGCCATGGGCATGCTCTACTTGCGCGATTCGCGCGCCTGC
AAGGGCGCAGGAGGAATTGA

Downstream 100 bases:

>100_bases
GCCCTGGGGATGCGCGTCCAGCATCCCTGCGGCTCCAACGAAGTGAGGAAACCCCGTCGGTGAGCATTGAGAGGGACATC
GCGCTGCTTCGGTCAGTCGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPNAWKILVVEDDPELRDALIEQLALQDEFEPVPAETAAGAMELAKNGAIDLVIMDVGLPDMDGREAVRLMRRSGFKAPI
LMLTGHDTDSDTILGLEAGANDYIIKPFRFAVLLARLRAQMRSHEASEDAVFAIGPYSFRPGAKLLLTDRGSKIRLTEKE
TAILRYLYRAGKTPVPRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEPDPSNPTLLATQAGGYKLVP

Sequences:

>Translated_228_residues
MPNAWKILVVEDDPELRDALIEQLALQDEFEPVPAETAAGAMELAKNGAIDLVIMDVGLPDMDGREAVRLMRRSGFKAPI
LMLTGHDTDSDTILGLEAGANDYIIKPFRFAVLLARLRAQMRSHEASEDAVFAIGPYSFRPGAKLLLTDRGSKIRLTEKE
TAILRYLYRAGKTPVPRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEPDPSNPTLLATQAGGYKLVP
>Mature_227_residues
PNAWKILVVEDDPELRDALIEQLALQDEFEPVPAETAAGAMELAKNGAIDLVIMDVGLPDMDGREAVRLMRRSGFKAPIL
MLTGHDTDSDTILGLEAGANDYIIKPFRFAVLLARLRAQMRSHEASEDAVFAIGPYSFRPGAKLLLTDRGSKIRLTEKET
AILRYLYRAGKTPVPRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEPDPSNPTLLATQAGGYKLVP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=37.4384236453202, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=33.0508474576271, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.5291479820628, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=34.6666666666667, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=35.5263157894737, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=31.7180616740088, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=30, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789402, Length=205, Percent_Identity=31.219512195122, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=30.3571428571429, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=29.4372294372294, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=30.6034482758621, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=253, Percent_Identity=25.296442687747, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788521, Length=122, Percent_Identity=33.6065573770492, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25311; Mature: 25180

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNAWKILVVEDDPELRDALIEQLALQDEFEPVPAETAAGAMELAKNGAIDLVIMDVGLP
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCC
DMDGREAVRLMRRSGFKAPILMLTGHDTDSDTILGLEAGANDYIIKPFRFAVLLARLRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHH
MRSHEASEDAVFAIGPYSFRPGAKLLLTDRGSKIRLTEKETAILRYLYRAGKTPVPRETL
HHHCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEPDPSNPTLLATQAGGYKLVP
HHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
PNAWKILVVEDDPELRDALIEQLALQDEFEPVPAETAAGAMELAKNGAIDLVIMDVGLP
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCC
DMDGREAVRLMRRSGFKAPILMLTGHDTDSDTILGLEAGANDYIIKPFRFAVLLARLRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHH
MRSHEASEDAVFAIGPYSFRPGAKLLLTDRGSKIRLTEKETAILRYLYRAGKTPVPRETL
HHHCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEPDPSNPTLLATQAGGYKLVP
HHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]