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The map label for this gene is cat1 [H]

Identifier: 154245674

GI number: 154245674

Start: 1943242

End: 1944768

Strand: Direct

Name: cat1 [H]

Synonym: Xaut_1730

Alternate gene names: 154245674

Gene position: 1943242-1944768 (Clockwise)

Preceding gene: 154245673

Following gene: 154245676

Centisome position: 36.6

GC content: 66.08

Gene sequence:

>1527_bases
ATGCCTCACGCGCGTATCCGCCTCTCTTCCCTCGCCGATAAAATCGTCTCCGCCGAGGAAGCGGCCGCCCACATCCAGGA
CGGGATGATCGTGGGCATGAGCGGGTTCACCCGCGCCGGCGAGGCCAAAGCGGTGCCCATGGCGCTCGCCGCCCGCGCCA
AGGAAGCCCACGCCGCCGGCCAGCCCCTGAAGATCACGCTCATCACCGGCGCCTCGCTGGGCAACGACCTCGACAAGCAG
ATGGCGGAAGCCCACCTGCTCTCGCGCCGCATCCCGTTCCAGTCCGACCCAGCGCTGCGCAAGGCCATCAATGCCGGCGA
GGTCATGTTCGTGGACCAGCACCTGTCGGAGACGGTGGAGCACCTGCGCACCAACCAGCTTGGCCCGGTGGATGTGGCGG
TGATCGAGGCGGTGGGCATCACCGCGCAGGGCGGCATCATTCCCACCACCTCGGTGGGCAATTCGGCCACCTTCGCCATC
CTCGCCAAGAAGGTGATCGTCGAGATCAATCTCACCCAGCCCATGGAGCTGGAGGGGCTGCACGATATCTACATCCCCAC
CCGCCGGCCGTTCCGCGAGCCGATCCCGGTGGTGGCGCCGGAAAGCCGGGTGGGACTGCCCTTCATCCCGATTCCGGCGG
AGAAGATCGCGGCCATCGTCATCACCCAGAAGCTGGACAGCGCCTCCAACGTGCTGCCGCCGGACCACGAGACGGCGGCC
ATCGCCTCCCACCTCATGGAGTTCCTGAAGCACGAGGTGAAGATCGGCCGGCTCACCAACCGTCTGCAGCCGCTGCAGGC
CGGCATCGGCACCATCGCCAACGCGGTGATGCACGGCTTCATCGAGAGCCCGTTCTCAGACCTCACCATGTATTCGGAGG
TGCTGCAGGATTCCACCTTCGACCTGTTCGACGCCGGCAAGCTGAACTTCGCCTCGGGCTCGTCCGTCACCCTGTCCAAG
GCCAAGCACGACCAGGTGATGCCGCGCATCGCCGACTATAAATCCCGGCTCATCCTGCGCCCGCAGGAGATCTCCAACCA
TCCGGAGATCATCCGCCGGCTCGGCCTCATCGGCATCAACACGGCGCTGGAATTCGACATCTTCGGCAATGTGAACTCCA
CCCACGTGGGCGGCACCGGCATGATGAACGGCATCGGTGGCTCGGGGGATTTCGCCCGCAACGCCTATCTGTCGGTGTTC
GTCACCAAGTCCATCGCCAAGGGCGGCGCGCTGTCTTCCGTGGTGCCCATGGTGAGCCATGTGGACCACACCGAGCACGA
CGTGGACATCCTCGTCACCGAGCAGGGCCTGGCCGACCTGCGCGAGCTGGCACCGCGCGAGCGGGCGCGGGTGATCATCG
ACAATTGCGTCCACCCGCTCTATCGCGACGCCCTGGACGACTATTTCGCCCGGGGTTGCGCGCGTGGCGGCCACACCCCG
CACATCATCGAGGAAGCCCTCTCCTGGCATGTGAAGGCGCGCGAGACCGGCTCCATGCTGCCCGGGCAGGACCTGAAGAT
CGCCTGA

Upstream 100 bases:

>100_bases
ATCGTCGCGTGATAGAGGTTTTCTCTTAAGTCGAATTCCAGCCATAGGCTGCCTCTCGCTATGCGCGATGGGATGGGCTC
ATGACAGGGACGGCCTCTCC

Downstream 100 bases:

>100_bases
GCGCCTGCCTGGAAATTCAGAAGAGCATAACCGCAATCACCCCCGGTCATGCCCGGCCTTGTGCCGGGCATCCACGCCGA
GCCGCTTGCGACGACCTACG

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MPHARIRLSSLADKIVSAEEAAAHIQDGMIVGMSGFTRAGEAKAVPMALAARAKEAHAAGQPLKITLITGASLGNDLDKQ
MAEAHLLSRRIPFQSDPALRKAINAGEVMFVDQHLSETVEHLRTNQLGPVDVAVIEAVGITAQGGIIPTTSVGNSATFAI
LAKKVIVEINLTQPMELEGLHDIYIPTRRPFREPIPVVAPESRVGLPFIPIPAEKIAAIVITQKLDSASNVLPPDHETAA
IASHLMEFLKHEVKIGRLTNRLQPLQAGIGTIANAVMHGFIESPFSDLTMYSEVLQDSTFDLFDAGKLNFASGSSVTLSK
AKHDQVMPRIADYKSRLILRPQEISNHPEIIRRLGLIGINTALEFDIFGNVNSTHVGGTGMMNGIGGSGDFARNAYLSVF
VTKSIAKGGALSSVVPMVSHVDHTEHDVDILVTEQGLADLRELAPRERARVIIDNCVHPLYRDALDDYFARGCARGGHTP
HIIEEALSWHVKARETGSMLPGQDLKIA

Sequences:

>Translated_508_residues
MPHARIRLSSLADKIVSAEEAAAHIQDGMIVGMSGFTRAGEAKAVPMALAARAKEAHAAGQPLKITLITGASLGNDLDKQ
MAEAHLLSRRIPFQSDPALRKAINAGEVMFVDQHLSETVEHLRTNQLGPVDVAVIEAVGITAQGGIIPTTSVGNSATFAI
LAKKVIVEINLTQPMELEGLHDIYIPTRRPFREPIPVVAPESRVGLPFIPIPAEKIAAIVITQKLDSASNVLPPDHETAA
IASHLMEFLKHEVKIGRLTNRLQPLQAGIGTIANAVMHGFIESPFSDLTMYSEVLQDSTFDLFDAGKLNFASGSSVTLSK
AKHDQVMPRIADYKSRLILRPQEISNHPEIIRRLGLIGINTALEFDIFGNVNSTHVGGTGMMNGIGGSGDFARNAYLSVF
VTKSIAKGGALSSVVPMVSHVDHTEHDVDILVTEQGLADLRELAPRERARVIIDNCVHPLYRDALDDYFARGCARGGHTP
HIIEEALSWHVKARETGSMLPGQDLKIA
>Mature_507_residues
PHARIRLSSLADKIVSAEEAAAHIQDGMIVGMSGFTRAGEAKAVPMALAARAKEAHAAGQPLKITLITGASLGNDLDKQM
AEAHLLSRRIPFQSDPALRKAINAGEVMFVDQHLSETVEHLRTNQLGPVDVAVIEAVGITAQGGIIPTTSVGNSATFAIL
AKKVIVEINLTQPMELEGLHDIYIPTRRPFREPIPVVAPESRVGLPFIPIPAEKIAAIVITQKLDSASNVLPPDHETAAI
ASHLMEFLKHEVKIGRLTNRLQPLQAGIGTIANAVMHGFIESPFSDLTMYSEVLQDSTFDLFDAGKLNFASGSSVTLSKA
KHDQVMPRIADYKSRLILRPQEISNHPEIIRRLGLIGINTALEFDIFGNVNSTHVGGTGMMNGIGGSGDFARNAYLSVFV
TKSIAKGGALSSVVPMVSHVDHTEHDVDILVTEQGLADLRELAPRERARVIIDNCVHPLYRDALDDYFARGCARGGHTPH
IIEEALSWHVKARETGSMLPGQDLKIA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=46.5020576131687, Blast_Score=420, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6319456, Length=516, Percent_Identity=42.0542635658915, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54785; Mature: 54654

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHARIRLSSLADKIVSAEEAAAHIQDGMIVGMSGFTRAGEAKAVPMALAARAKEAHAAG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
QPLKITLITGASLGNDLDKQMAEAHLLSRRIPFQSDPALRKAINAGEVMFVDQHLSETVE
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHH
HLRTNQLGPVDVAVIEAVGITAQGGIIPTTSVGNSATFAILAKKVIVEINLTQPMELEGL
HHHCCCCCCCHHHHHHHHCEEECCCEEECCCCCCCHHHHHEEEEEEEEEECCCCCCCCCC
HDIYIPTRRPFREPIPVVAPESRVGLPFIPIPAEKIAAIVITQKLDSASNVLPPDHETAA
CEEECCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHEEEHEEHHHCCCCCCCCCCCHHHH
IASHLMEFLKHEVKIGRLTNRLQPLQAGIGTIANAVMHGFIESPFSDLTMYSEVLQDSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
DLFDAGKLNFASGSSVTLSKAKHDQVMPRIADYKSRLILRPQEISNHPEIIRRLGLIGIN
CCCCCCCEEECCCCCEEECHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEEC
TALEFDIFGNVNSTHVGGTGMMNGIGGSGDFARNAYLSVFVTKSIAKGGALSSVVPMVSH
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEHHHHCCCCHHHHHHHHHH
VDHTEHDVDILVTEQGLADLRELAPRERARVIIDNCVHPLYRDALDDYFARGCARGGHTP
CCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HIIEEALSWHVKARETGSMLPGQDLKIA
HHHHHHHHHHHEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
PHARIRLSSLADKIVSAEEAAAHIQDGMIVGMSGFTRAGEAKAVPMALAARAKEAHAAG
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
QPLKITLITGASLGNDLDKQMAEAHLLSRRIPFQSDPALRKAINAGEVMFVDQHLSETVE
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHH
HLRTNQLGPVDVAVIEAVGITAQGGIIPTTSVGNSATFAILAKKVIVEINLTQPMELEGL
HHHCCCCCCCHHHHHHHHCEEECCCEEECCCCCCCHHHHHEEEEEEEEEECCCCCCCCCC
HDIYIPTRRPFREPIPVVAPESRVGLPFIPIPAEKIAAIVITQKLDSASNVLPPDHETAA
CEEECCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHEEEHEEHHHCCCCCCCCCCCHHHH
IASHLMEFLKHEVKIGRLTNRLQPLQAGIGTIANAVMHGFIESPFSDLTMYSEVLQDSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
DLFDAGKLNFASGSSVTLSKAKHDQVMPRIADYKSRLILRPQEISNHPEIIRRLGLIGIN
CCCCCCCEEECCCCCEEECHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEEC
TALEFDIFGNVNSTHVGGTGMMNGIGGSGDFARNAYLSVFVTKSIAKGGALSSVVPMVSH
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEHHHHCCCCHHHHHHHHHH
VDHTEHDVDILVTEQGLADLRELAPRERARVIIDNCVHPLYRDALDDYFARGCARGGHTP
CCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
HIIEEALSWHVKARETGSMLPGQDLKIA
HHHHHHHHHHHEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]