Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 154245552

GI number: 154245552

Start: 1820387

End: 1820824

Strand: Reverse

Name: etfA [H]

Synonym: Xaut_1606

Alternate gene names: 154245552

Gene position: 1820824-1820387 (Counterclockwise)

Preceding gene: 154245553

Following gene: 154245551

Centisome position: 34.3

GC content: 66.21

Gene sequence:

>438_bases
ATGATCGGTACCAAACTGGGTCTCGAAACCGTCCGCCGTATGGCCGAGGAGACCATCGCGGCCTCCGACCGTCCGGAGCT
GACGGCGGCGAAGATCATCGTCTCCGGCGGCCGCGCTTTGGGCTCGCGGGAGAAGTTCGCCGAGCTGATCGAGCCGCTGG
CAGACGTGCTGGGCGCCTCACGCGCCGCGGTGGATGCGGGCTATGCCCCCAACGACTGGCAGGTGGGCCAGACCGGCAAG
GTGGCGGCCCCGGAGCTGTACATCGCGACGGGCATTTCCGGCGCCATCCAGCATCTGGCCGGCATGAAGGACAGCAAGGT
CATCGTCGCAGTCAACAAGGACGAGGAGGCCCCCATCTTCCAGGTGGCCGACTACGGCCTCGTCGGCGACATCAACACCG
TCATCCCCGAGCTCAAGGCGGAGATCGGAAAGATGTGA

Upstream 100 bases:

>100_bases
GGCCTTCTAGGTCGACGTCCGCGAAGCGGTGGCTGAAGGACGCTACGTTCATCGGCTGCCCGCCGGGGGCGATGCGGTTG
ATCCGCACGAAATGGCCTAG

Downstream 100 bases:

>100_bases
GGCTGAGGCGGCCCTCATCGCCGACATCGCGCGTGCCCTGGTGGACGAGGAGGTTTCGTCCGCCAGGGCTGGCGGAGATG
GTCTCGGTGACCTGCGCTGT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIGTKLGLETVRRMAEETIAASDRPELTAAKIIVSGGRALGSREKFAELIEPLADVLGASRAAVDAGYAPNDWQVGQTGK
VAAPELYIATGISGAIQHLAGMKDSKVIVAVNKDEEAPIFQVADYGLVGDINTVIPELKAEIGKM

Sequences:

>Translated_145_residues
MIGTKLGLETVRRMAEETIAASDRPELTAAKIIVSGGRALGSREKFAELIEPLADVLGASRAAVDAGYAPNDWQVGQTGK
VAAPELYIATGISGAIQHLAGMKDSKVIVAVNKDEEAPIFQVADYGLVGDINTVIPELKAEIGKM
>Mature_145_residues
MIGTKLGLETVRRMAEETIAASDRPELTAAKIIVSGGRALGSREKFAELIEPLADVLGASRAAVDAGYAPNDWQVGQTGK
VAAPELYIATGISGAIQHLAGMKDSKVIVAVNKDEEAPIFQVADYGLVGDINTVIPELKAEIGKM

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=127, Percent_Identity=69.2913385826772, Blast_Score=176, Evalue=7e-45,
Organism=Homo sapiens, GI189181759, Length=127, Percent_Identity=69.2913385826772, Blast_Score=175, Evalue=1e-44,
Organism=Escherichia coli, GI1786226, Length=128, Percent_Identity=42.1875, Blast_Score=97, Evalue=4e-22,
Organism=Escherichia coli, GI1787990, Length=134, Percent_Identity=38.8059701492537, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI87082157, Length=118, Percent_Identity=35.5932203389831, Blast_Score=64, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=130, Percent_Identity=66.1538461538461, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325261, Length=130, Percent_Identity=61.5384615384615, Blast_Score=169, Evalue=2e-43,
Organism=Drosophila melanogaster, GI17136898, Length=138, Percent_Identity=60.8695652173913, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24652801, Length=138, Percent_Identity=60.8695652173913, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 15204; Mature: 15204

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGTKLGLETVRRMAEETIAASDRPELTAAKIIVSGGRALGSREKFAELIEPLADVLGAS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCC
RAAVDAGYAPNDWQVGQTGKVAAPELYIATGISGAIQHLAGMKDSKVIVAVNKDEEAPIF
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEE
QVADYGLVGDINTVIPELKAEIGKM
EECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGTKLGLETVRRMAEETIAASDRPELTAAKIIVSGGRALGSREKFAELIEPLADVLGAS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCC
RAAVDAGYAPNDWQVGQTGKVAAPELYIATGISGAIQHLAGMKDSKVIVAVNKDEEAPIF
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEE
QVADYGLVGDINTVIPELKAEIGKM
EECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]