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The map label for this gene is siaT [H]

Identifier: 154245483

GI number: 154245483

Start: 1745155

End: 1747071

Strand: Reverse

Name: siaT [H]

Synonym: Xaut_1536

Alternate gene names: 154245483

Gene position: 1747071-1745155 (Counterclockwise)

Preceding gene: 154245484

Following gene: 154245482

Centisome position: 32.91

GC content: 68.02

Gene sequence:

>1917_bases
ATGGATCGCGCAATCACGGACCCGGTAATCACCGAGCCGAATATGGCTCATACCCATATGCTGGCCCCGGACGAGCCGGC
CGGCGGCTGGCGCAGGGGCGTGCTCAAGGTGGAGCGCGCTCTGATCAAGATGGTGGAGATTCCGGCGGCACTCCTGGTGC
TGGCGGAAGTGGTGGTGCTCTTCGTCGGCGTGGTGATGCGCTACTTCGTGCATTCGCCCATCGTCTGGTCGGACGAGCTG
GCCTCGGTCCTGTTCATCTGGCTGGCCATGCTGGGCTCCGTGGTGGCGCTCCAGCGCGGTGAGCACATGCGCATGACCGC
GCTGGTGGGGGCGCTGCCTCTGCCGAAGCGCGCGGTGCTGGAAACGCTGGCCGTCGCCGCCCCGCTCATCTTCCTCGTGG
CCATGCTCCATCCCAGCCTGGAATATGCCGAGGACGAGATGTTCGTCACCCTGCCCGCCCTCGACGTGCCCAATACGTGG
AAGGCGGCGGCACTGCCAGTGGGCCTCGCGCTCATGGGCATCGTCGCGATGCTCAAGCTCGTCCGCAACGCCAACCCCAT
GCAGGTGGCGGGCGTCATCGCCTTCCTGGCGGCGCTGACCGCCGTGGGCATCCTCGGCACGCCGGTTCTGAAGACGCTGG
GCAACATCAACCTCGTGATCTTCTTTGTCGGCCTGGTGGCGGCGGGGGTGTTCGCGGGGGTGCCCATCGCCTTCTCCTTC
GGCCTCGCCACGCTCGCCTATCTCTCCTTCACCACCAATGCCCCGCTGACGGTGGTGGTGGGCCGCATGGACGAGGGCAT
GAGCCACCTCATCCTGCTCTCGGTGCCGCTGTTCGTGTTCCTCGGCATGCTGATCGAGATGACCGGCATGGCGCGGGCCA
TGGTGGGCTTCCTCGCGAGCCTCCTCGGCCATGTGCGGGGCGGCCTGTCCTACGTGCTGATCGGCGCCATGTATCTCGTC
TCGGGCATTTCCGGCTCCAAGGCGGCGGACATGGCGGCGGTGACCCCGGTGCTGTTCCCGGAGATGATCAAGCGCGGCGC
CAAGCCCGGCGACCTCGTGGCCCTGCTGGCCGCCACCGGCGCGCAGACCGAGACCATCCCGCCGAGCCTGGTGCTCATCA
CCATCGGCTCGGTCACCGGCGTGTCCATCGCCGCCCTGTTCGCCGGCGGCCTGATGCCCGCCGTCGTTCTCGGCGTCATG
CTGTGCATCCTGGTGCGCTGGCGCTACCGCAACGAGGACCTGTCCGGCGTGCGCCGGGCGAGCAGGACGGAAATCCTGCG
CGCCCTCGCCATCGCCGTGCCGGCCATCGCCTTGCCGTTCGTCATCCGGGCCGCGGTGATGGAAGGCATCGCCACCGCCA
CCGAGGTCTCCACCATCGGCATCGTCTATTCGGTGGTGGTGGGACTGCTGATCTACCGGCAGTTCGACTTCAAGCGGCTG
ATGCCCATGCTCACCGCCACGGCGGCGCTCTCGGGTGCCATCCTGCTGATCATCGGCGCGGCCACCGGCATGGCCTGGGC
GCTCACCCAGTCCGGCTTCTCCCAGGAACTGGCGCGGGTGATGGGCGGCCTGCCCGGCGGGGCGGCGACCTTCATGGTGG
TGTCTATCGTCGCCTTCATCATCCTGGGATCGGTGCTGGAGGGCATCCCGGCCATCGTGCTGTTCGGGCCGCTGCTGTTC
CCCATCGCACGCAGCATGGGCATCCATGAAGTCCACTATGCCATGGTGGTCATCCTCTCCATGGGCCTCGGCCTGTTCGC
CCCGCCTTTCGGCGTCGGCTACTACTGCGCCACGGCCATCGGCGGGGTCAGCCCCGACGCCGGCATGAAGCCCATCGTCG
GCTACATGGCCGCCCTGCTCATCGGCCTCGCGCTGGTCGCGGCCGTGCCGTGGTTCTCCATCGGCTTCCTGCCCTGA

Upstream 100 bases:

>100_bases
ACGCTTGCCGAGACTTCCTTCTATGCCGATTGGCGTGCCAAATACGGCAACGAAGCCTGGTCGCTCCTTGAGGCGTCCGT
CGGCAAGCTGGGGTGACGTC

Downstream 100 bases:

>100_bases
TCTCCCTTTGATGCGCCGGGGCGCGTGCCCCGGCGCCAGCCAAGGTCGCTCACCATGTCGCTCATTGCCTCCACTGGCTT
CGCCGAAGCCGGTAACGCCC

Product: TRAP C4-dicarboxylate transport system permease DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MDRAITDPVITEPNMAHTHMLAPDEPAGGWRRGVLKVERALIKMVEIPAALLVLAEVVVLFVGVVMRYFVHSPIVWSDEL
ASVLFIWLAMLGSVVALQRGEHMRMTALVGALPLPKRAVLETLAVAAPLIFLVAMLHPSLEYAEDEMFVTLPALDVPNTW
KAAALPVGLALMGIVAMLKLVRNANPMQVAGVIAFLAALTAVGILGTPVLKTLGNINLVIFFVGLVAAGVFAGVPIAFSF
GLATLAYLSFTTNAPLTVVVGRMDEGMSHLILLSVPLFVFLGMLIEMTGMARAMVGFLASLLGHVRGGLSYVLIGAMYLV
SGISGSKAADMAAVTPVLFPEMIKRGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFAGGLMPAVVLGVM
LCILVRWRYRNEDLSGVRRASRTEILRALAIAVPAIALPFVIRAAVMEGIATATEVSTIGIVYSVVVGLLIYRQFDFKRL
MPMLTATAALSGAILLIIGAATGMAWALTQSGFSQELARVMGGLPGGAATFMVVSIVAFIILGSVLEGIPAIVLFGPLLF
PIARSMGIHEVHYAMVVILSMGLGLFAPPFGVGYYCATAIGGVSPDAGMKPIVGYMAALLIGLALVAAVPWFSIGFLP

Sequences:

>Translated_638_residues
MDRAITDPVITEPNMAHTHMLAPDEPAGGWRRGVLKVERALIKMVEIPAALLVLAEVVVLFVGVVMRYFVHSPIVWSDEL
ASVLFIWLAMLGSVVALQRGEHMRMTALVGALPLPKRAVLETLAVAAPLIFLVAMLHPSLEYAEDEMFVTLPALDVPNTW
KAAALPVGLALMGIVAMLKLVRNANPMQVAGVIAFLAALTAVGILGTPVLKTLGNINLVIFFVGLVAAGVFAGVPIAFSF
GLATLAYLSFTTNAPLTVVVGRMDEGMSHLILLSVPLFVFLGMLIEMTGMARAMVGFLASLLGHVRGGLSYVLIGAMYLV
SGISGSKAADMAAVTPVLFPEMIKRGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFAGGLMPAVVLGVM
LCILVRWRYRNEDLSGVRRASRTEILRALAIAVPAIALPFVIRAAVMEGIATATEVSTIGIVYSVVVGLLIYRQFDFKRL
MPMLTATAALSGAILLIIGAATGMAWALTQSGFSQELARVMGGLPGGAATFMVVSIVAFIILGSVLEGIPAIVLFGPLLF
PIARSMGIHEVHYAMVVILSMGLGLFAPPFGVGYYCATAIGGVSPDAGMKPIVGYMAALLIGLALVAAVPWFSIGFLP
>Mature_638_residues
MDRAITDPVITEPNMAHTHMLAPDEPAGGWRRGVLKVERALIKMVEIPAALLVLAEVVVLFVGVVMRYFVHSPIVWSDEL
ASVLFIWLAMLGSVVALQRGEHMRMTALVGALPLPKRAVLETLAVAAPLIFLVAMLHPSLEYAEDEMFVTLPALDVPNTW
KAAALPVGLALMGIVAMLKLVRNANPMQVAGVIAFLAALTAVGILGTPVLKTLGNINLVIFFVGLVAAGVFAGVPIAFSF
GLATLAYLSFTTNAPLTVVVGRMDEGMSHLILLSVPLFVFLGMLIEMTGMARAMVGFLASLLGHVRGGLSYVLIGAMYLV
SGISGSKAADMAAVTPVLFPEMIKRGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFAGGLMPAVVLGVM
LCILVRWRYRNEDLSGVRRASRTEILRALAIAVPAIALPFVIRAAVMEGIATATEVSTIGIVYSVVVGLLIYRQFDFKRL
MPMLTATAALSGAILLIIGAATGMAWALTQSGFSQELARVMGGLPGGAATFMVVSIVAFIILGSVLEGIPAIVLFGPLLF
PIARSMGIHEVHYAMVVILSMGLGLFAPPFGVGYYCATAIGGVSPDAGMKPIVGYMAALLIGLALVAAVPWFSIGFLP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=373, Percent_Identity=27.3458445040214, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 66813; Mature: 66813

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAITDPVITEPNMAHTHMLAPDEPAGGWRRGVLKVERALIKMVEIPAALLVLAEVVVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGVVMRYFVHSPIVWSDELASVLFIWLAMLGSVVALQRGEHMRMTALVGALPLPKRAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
ETLAVAAPLIFLVAMLHPSLEYAEDEMFVTLPALDVPNTWKAAALPVGLALMGIVAMLKL
HHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRNANPMQVAGVIAFLAALTAVGILGTPVLKTLGNINLVIFFVGLVAAGVFAGVPIAFSF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
GLATLAYLSFTTNAPLTVVVGRMDEGMSHLILLSVPLFVFLGMLIEMTGMARAMVGFLAS
HHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGHVRGGLSYVLIGAMYLVSGISGSKAADMAAVTPVLFPEMIKRGAKPGDLVALLAATG
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
AQTETIPPSLVLITIGSVTGVSIAALFAGGLMPAVVLGVMLCILVRWRYRNEDLSGVRRA
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRTEILRALAIAVPAIALPFVIRAAVMEGIATATEVSTIGIVYSVVVGLLIYRQFDFKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPMLTATAALSGAILLIIGAATGMAWALTQSGFSQELARVMGGLPGGAATFMVVSIVAFI
HHHHHHHHHHHCHHHHEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ILGSVLEGIPAIVLFGPLLFPIARSMGIHEVHYAMVVILSMGLGLFAPPFGVGYYCATAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GGVSPDAGMKPIVGYMAALLIGLALVAAVPWFSIGFLP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDRAITDPVITEPNMAHTHMLAPDEPAGGWRRGVLKVERALIKMVEIPAALLVLAEVVVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGVVMRYFVHSPIVWSDELASVLFIWLAMLGSVVALQRGEHMRMTALVGALPLPKRAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
ETLAVAAPLIFLVAMLHPSLEYAEDEMFVTLPALDVPNTWKAAALPVGLALMGIVAMLKL
HHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRNANPMQVAGVIAFLAALTAVGILGTPVLKTLGNINLVIFFVGLVAAGVFAGVPIAFSF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
GLATLAYLSFTTNAPLTVVVGRMDEGMSHLILLSVPLFVFLGMLIEMTGMARAMVGFLAS
HHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGHVRGGLSYVLIGAMYLVSGISGSKAADMAAVTPVLFPEMIKRGAKPGDLVALLAATG
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
AQTETIPPSLVLITIGSVTGVSIAALFAGGLMPAVVLGVMLCILVRWRYRNEDLSGVRRA
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRTEILRALAIAVPAIALPFVIRAAVMEGIATATEVSTIGIVYSVVVGLLIYRQFDFKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPMLTATAALSGAILLIIGAATGMAWALTQSGFSQELARVMGGLPGGAATFMVVSIVAFI
HHHHHHHHHHHCHHHHEEEHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ILGSVLEGIPAIVLFGPLLFPIARSMGIHEVHYAMVVILSMGLGLFAPPFGVGYYCATAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GGVSPDAGMKPIVGYMAALLIGLALVAAVPWFSIGFLP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]