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The map label for this gene is aprE [H]

Identifier: 154245456

GI number: 154245456

Start: 1716783

End: 1718198

Strand: Reverse

Name: aprE [H]

Synonym: Xaut_1509

Alternate gene names: 154245456

Gene position: 1718198-1716783 (Counterclockwise)

Preceding gene: 154245457

Following gene: 154245455

Centisome position: 32.36

GC content: 69.07

Gene sequence:

>1416_bases
ATGCGGTTTCTTGAAAGCTGGTTCAGCCCCCGCGCCGCACTGGCCGGAGCGGACATGGGAGCTGCCGCCGGCGTGCGACC
AACCACACCGGCTCCCCCGACCGCACCGGGCGCGCCCCCGCCGCCCTCGGGCGACTACAATGCCATGGCCCGCATCGGCT
ACGCCGTCATCGCCTTCACCTTCCTCGGTGTCAGCGGCTGGGCGGCGCTGGCCCGGGTGGATAGCGCCGTCATCGCCCCC
GGCGTGGTGGCAGTGGAGAGCAAGCGGCAGGTGGTGCAGCACCTGGAAGGCGGGATCGTCGCGGAAATCCTCGTCAAGGA
AGGCGAGGAGGTGGTGAAGGACCAGGTGCTGTTCCGCCTCGACCCGACCCAGTCCAAGGCCAGCGACGACGCCGCACTGG
CCCAGCTGCGCGCCGCCCTGGCGCTGGAGGCGCGGCTGATTGCGGAGCGGGACGAGCGGGAGCAGATCGTCTTTCCCGAC
GATCTCCTCGCCAATGCCGGCCAACCCGTGGTGCGCGACGCCATGGCCGACCAGCTCACCCAGTTCCGCGACCGGCGCGC
CGCCTTCAAGAGCCAGACCGGCATCCTGGAAAACCGCGCCGAGCAGTCGGGCCACGAGATCGAGGGCCTGACGCAGGAGC
GGCTCTCCGCCGAGCAGCAGTTGATGTTCATCGACGACGAGCTGGATTCCCTCCGCCAGCTGGAGCAGAAGCGGCTGGTG
AACAAGTCCCGCGTCTCCCAGATCGAGCGGGAGAAGGCGCGGCTCGAAGGCGTGGTCGGCCGCAACACCGCCGACACCGC
CAAGGTGCGCGGCTCCATCGGCGAACTCACCATGCAGGTGTCCCAGTTGCGCCAGCAGCGGGCCGAGGACATCGGCAAGC
AATTGCTGGAGGTGCGCCAGAGGATCGCCGAGCTGACCGAGAAGGTGCGGGTGACGCGCAACGTGCTCGGGCGCATCGAC
ATCCGCGCCCCGCGCTCCGGCACGGTGCAGAACATCAACGCCCGCGCCTACACGGTCGGCGCGGTGGCGCGGGCTGGCGA
CACGCTGCTGGAGATCGTGCCCCTGGACGAGCCTTTGGTGGTGGATGCCCAGGTGCCGGTGCAGGACATCGACCGGCTCA
AGAAGGACGATGCGGTGGAGGTGCGCTTCCCCGCCTTCCACGATCGCACCACCCCCATGGTGATGGGCAGGCTCAAGACC
GTCTCGCGCGACCGGCTGGTGGACGAGACCACCCACCAGCCCTACTTCCTCGCCCGGGTGGCTGTGGCCGAGACCGACAT
TCCCCCGGCCCTGAAACAGCGCCTCGTGCCCGGCATGAATGCGGAAGTCGCCTTCTATGTGGGCGAGCGCTCCGTCCTGA
GCTATCTGGTGCGTCCCATCACCGATGCCTTCTCCCGCGCCTTCACGGAGCGCTGA

Upstream 100 bases:

>100_bases
AGCCGTCCGCCGCTGGCGAGCGTTCCCCTCGGGACGGCGGCGAACGAAATCCCGCCCAATATGCCCGGCGCCCCACGGCC
CCCGTTCATGGAGGATGGCC

Downstream 100 bases:

>100_bases
GACGGCCGGGGTCGGGCGCCACCCGAACCGTTCGGGGAAAAGGAGACGGGGATGTTGAAGATCTGGGGCCGGCTGAACTC
GGTGAACGTGGAAAAGGTGG

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRFLESWFSPRAALAGADMGAAAGVRPTTPAPPTAPGAPPPPSGDYNAMARIGYAVIAFTFLGVSGWAALARVDSAVIAP
GVVAVESKRQVVQHLEGGIVAEILVKEGEEVVKDQVLFRLDPTQSKASDDAALAQLRAALALEARLIAERDEREQIVFPD
DLLANAGQPVVRDAMADQLTQFRDRRAAFKSQTGILENRAEQSGHEIEGLTQERLSAEQQLMFIDDELDSLRQLEQKRLV
NKSRVSQIEREKARLEGVVGRNTADTAKVRGSIGELTMQVSQLRQQRAEDIGKQLLEVRQRIAELTEKVRVTRNVLGRID
IRAPRSGTVQNINARAYTVGAVARAGDTLLEIVPLDEPLVVDAQVPVQDIDRLKKDDAVEVRFPAFHDRTTPMVMGRLKT
VSRDRLVDETTHQPYFLARVAVAETDIPPALKQRLVPGMNAEVAFYVGERSVLSYLVRPITDAFSRAFTER

Sequences:

>Translated_471_residues
MRFLESWFSPRAALAGADMGAAAGVRPTTPAPPTAPGAPPPPSGDYNAMARIGYAVIAFTFLGVSGWAALARVDSAVIAP
GVVAVESKRQVVQHLEGGIVAEILVKEGEEVVKDQVLFRLDPTQSKASDDAALAQLRAALALEARLIAERDEREQIVFPD
DLLANAGQPVVRDAMADQLTQFRDRRAAFKSQTGILENRAEQSGHEIEGLTQERLSAEQQLMFIDDELDSLRQLEQKRLV
NKSRVSQIEREKARLEGVVGRNTADTAKVRGSIGELTMQVSQLRQQRAEDIGKQLLEVRQRIAELTEKVRVTRNVLGRID
IRAPRSGTVQNINARAYTVGAVARAGDTLLEIVPLDEPLVVDAQVPVQDIDRLKKDDAVEVRFPAFHDRTTPMVMGRLKT
VSRDRLVDETTHQPYFLARVAVAETDIPPALKQRLVPGMNAEVAFYVGERSVLSYLVRPITDAFSRAFTER
>Mature_471_residues
MRFLESWFSPRAALAGADMGAAAGVRPTTPAPPTAPGAPPPPSGDYNAMARIGYAVIAFTFLGVSGWAALARVDSAVIAP
GVVAVESKRQVVQHLEGGIVAEILVKEGEEVVKDQVLFRLDPTQSKASDDAALAQLRAALALEARLIAERDEREQIVFPD
DLLANAGQPVVRDAMADQLTQFRDRRAAFKSQTGILENRAEQSGHEIEGLTQERLSAEQQLMFIDDELDSLRQLEQKRLV
NKSRVSQIEREKARLEGVVGRNTADTAKVRGSIGELTMQVSQLRQQRAEDIGKQLLEVRQRIAELTEKVRVTRNVLGRID
IRAPRSGTVQNINARAYTVGAVARAGDTLLEIVPLDEPLVVDAQVPVQDIDRLKKDDAVEVRFPAFHDRTTPMVMGRLKT
VSRDRLVDETTHQPYFLARVAVAETDIPPALKQRLVPGMNAEVAFYVGERSVLSYLVRPITDAFSRAFTER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51818; Mature: 51818

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLESWFSPRAALAGADMGAAAGVRPTTPAPPTAPGAPPPPSGDYNAMARIGYAVIAFT
CCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLGVSGWAALARVDSAVIAPGVVAVESKRQVVQHLEGGIVAEILVKEGEEVVKDQVLFRL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHEEE
DPTQSKASDDAALAQLRAALALEARLIAERDEREQIVFPDDLLANAGQPVVRDAMADQLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCCCCHHHHHHHHHHHH
QFRDRRAAFKSQTGILENRAEQSGHEIEGLTQERLSAEQQLMFIDDELDSLRQLEQKRLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHCHHHHEEEEHHHHHHHHHHHHHHHH
NKSRVSQIEREKARLEGVVGRNTADTAKVRGSIGELTMQVSQLRQQRAEDIGKQLLEVRQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAELTEKVRVTRNVLGRIDIRAPRSGTVQNINARAYTVGAVARAGDTLLEIVPLDEPLV
HHHHHHHHHHHHHHHHHCEEECCCCCCCCEECCCCEEEHHHHHHCCCCEEEEEECCCCEE
VDAQVPVQDIDRLKKDDAVEVRFPAFHDRTTPMVMGRLKTVSRDRLVDETTHQPYFLARV
EECCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AVAETDIPPALKQRLVPGMNAEVAFYVGERSVLSYLVRPITDAFSRAFTER
HHHCCCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLESWFSPRAALAGADMGAAAGVRPTTPAPPTAPGAPPPPSGDYNAMARIGYAVIAFT
CCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLGVSGWAALARVDSAVIAPGVVAVESKRQVVQHLEGGIVAEILVKEGEEVVKDQVLFRL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHEEE
DPTQSKASDDAALAQLRAALALEARLIAERDEREQIVFPDDLLANAGQPVVRDAMADQLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCCCCHHHHHHHHHHHH
QFRDRRAAFKSQTGILENRAEQSGHEIEGLTQERLSAEQQLMFIDDELDSLRQLEQKRLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHCHHHHEEEEHHHHHHHHHHHHHHHH
NKSRVSQIEREKARLEGVVGRNTADTAKVRGSIGELTMQVSQLRQQRAEDIGKQLLEVRQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAELTEKVRVTRNVLGRIDIRAPRSGTVQNINARAYTVGAVARAGDTLLEIVPLDEPLV
HHHHHHHHHHHHHHHHHCEEECCCCCCCCEECCCCEEEHHHHHHCCCCEEEEEECCCCEE
VDAQVPVQDIDRLKKDDAVEVRFPAFHDRTTPMVMGRLKTVSRDRLVDETTHQPYFLARV
EECCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AVAETDIPPALKQRLVPGMNAEVAFYVGERSVLSYLVRPITDAFSRAFTER
HHHCCCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]