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The map label for this gene is ilvC [H]

Identifier: 154245437

GI number: 154245437

Start: 1699860

End: 1700879

Strand: Direct

Name: ilvC [H]

Synonym: Xaut_1490

Alternate gene names: 154245437

Gene position: 1699860-1700879 (Clockwise)

Preceding gene: 154245436

Following gene: 154245438

Centisome position: 32.02

GC content: 65.98

Gene sequence:

>1020_bases
ATGCGCGTTTACTACGATCGCGATGCCGACCTGAACCTGATCAAGGGCAAGAAGGTCGCCGTCGTCGGCTATGGCAGCCA
GGGCCATGCCCATGCGCTCAACATGCGCGACTCGGGCGTGAAGGAGGTCGTGGTCGCCCTGCGTCCCGGCTCCGCCACCG
CCAAGAAGGCCGAGGCCGAGGGCTTCAAGGTGATGAGCCCCGCCGACGCCGCCAAGTGGGCCGACGTGGTGATGATGCTC
ACCCCCGACGAGCTGCAGGGCGACATCTATCGCGAGAGCCTCGCCGACAACATGAAGCACGGCGCGGCGCTGCTGTTCGC
CCACGGCCTCAACGTACATTTCAACCTCATCGAGCCGCGCCCCGACCTCGACGTGCTGATGGTGGCCCCCAAGGGCCCCG
GCCACACCGTGCGCTCCGAATACCAGCGCGGCGGCGGCGTGCCGACCCTCATCGCCATCGCCCAGGACGCCTCGGGCAAC
GCCCATGACCTCGGCCTGTCCTACGCCTCCGCCATCGGCGGCGGCCGCGCCGGCGTCATCGAGACCACCTTCAAGGAAGA
GTGCGAGACCGACCTGTTCGGGGAGCAGGTGGTGCTCTGCGGCGGCCTCGTGGAGCTGATCCGCGCCGGCTTCGAGACCC
TGGTGGAAGCCGGCTACGCCCCGGAGATGGCCTATTTCGAGTGCCTCCACGAGGTGAAGCTCATCGTCGACCTCATCTAT
GAGGGCGGCATCGCCAACATGAACTATTCCATCTCCAACACCGCCGAGTATGGCGAATACGTCACCGGCCCCCGCATCAT
CACCCCCGAGACCAAGGCGGAGATGAAGCGCGTGCTCACCGACATCCAGACCGGCAAGTTCACCCGCGACTGGATGCTGG
AGAACAAGGTGAACCAGGCCTCCTTCAAGGCCACACGCGCCCGCGCCAACGCCCACCCCATCGAGGAAGTGGGCGAGAAG
CTGCGCGCCATGATGCCCTGGATCAAGGCCAAGGCCCTCGTGGACAAGACCAAGAACTGA

Upstream 100 bases:

>100_bases
CCGGCGCGAACGGCTGTTCCCATTTCCCGCGATCCGGTGCAAAGGGACGCCCGGCGCGGATCACACCGACATTCAAGACA
ACGCCCATAAGGAGACAACG

Downstream 100 bases:

>100_bases
GGTATTTAAGTGTGTCTTAGAATTTAGAGTTCGTTAGGTAATTGATAACGTCGCCCTGCTAAGCTCTTCCAGCAAAAGAC
GCTCTCTTCCAGCAAAAGAC

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAEGFKVMSPADAAKWADVVMML
TPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPRPDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGN
AHDLGLSYASAIGGGRAGVIETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQASFKATRARANAHPIEEVGEK
LRAMMPWIKAKALVDKTKN

Sequences:

>Translated_339_residues
MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAEGFKVMSPADAAKWADVVMML
TPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPRPDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGN
AHDLGLSYASAIGGGRAGVIETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQASFKATRARANAHPIEEVGEK
LRAMMPWIKAKALVDKTKN
>Mature_339_residues
MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAEGFKVMSPADAAKWADVVMML
TPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPRPDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGN
AHDLGLSYASAIGGGRAGVIETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQASFKATRARANAHPIEEVGEK
LRAMMPWIKAKALVDKTKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=297, Percent_Identity=39.3939393939394, Blast_Score=164, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323387, Length=265, Percent_Identity=34.7169811320755, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 36929; Mature: 36929

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAE
CEEEECCCCCCEEECCCEEEEEEECCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHCC
GFKVMSPADAAKWADVVMMLTPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPR
CEEEECCCCHHHHHCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEEECCC
PDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGNAHDLGLSYASAIGGGRAGVI
CCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEE
ETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQA
CCCCCCCCCCCCCCHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHH
SFKATRARANAHPIEEVGEKLRAMMPWIKAKALVDKTKN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAE
CEEEECCCCCCEEECCCEEEEEEECCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHCC
GFKVMSPADAAKWADVVMMLTPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPR
CEEEECCCCHHHHHCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEEECCC
PDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGNAHDLGLSYASAIGGGRAGVI
CCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEE
ETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
ECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQA
CCCCCCCCCCCCCCHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHH
SFKATRARANAHPIEEVGEKLRAMMPWIKAKALVDKTKN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA