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The map label for this gene is lig1 [H]

Identifier: 154245417

GI number: 154245417

Start: 1679891

End: 1681519

Strand: Reverse

Name: lig1 [H]

Synonym: Xaut_1470

Alternate gene names: 154245417

Gene position: 1681519-1679891 (Counterclockwise)

Preceding gene: 154245418

Following gene: 154245415

Centisome position: 31.67

GC content: 69.8

Gene sequence:

>1629_bases
ATGAACCGCTTCGCCGCCCTGCTCGACCGCATGTCCTATGAAGCCGGGCGCAACGCCAAGATCCGGCTGATGGCGGACTA
TTTCCGCACCACGCCGGACCCCGAGCGCGGCTTCGCCCTCGCGGCGCTCACCGGCGCGCTCTCCTTCGCCAACGCCAAGC
CCGGCGTGGTGCGCGCCCTCATCATGGAGCGGGCCGACCCGGTGCTGTTCGAGATGTCCTACGATTATGTGGGCGACCTC
TCGGAAACCGTCGCCCTCATGTGGCCGAGGCTGGAAGGCGCCCCGACCCACGCGCCGCTGCTGTCCGAGATCGTCCACGG
CCTCTCCACCCTCTCCCGCTCCACCCTGCCCCGCCGCCTTGCCGACTGGCTGGACGGGCTGGACGAAACCGGCCGCTGGG
CGCTGCTGAAGCTCATCACCGGCGCCATGCGGGTCGGCGCCTCCGCCCGCCTCGCCAAGACCGCGTTGGCAAGCCTTGGC
AGCGTCACGCCGGACGAGGTGGAACTGGTATGGCCCGGCCTCGCGCCACCCTATGAAGAGCTGTTCGCCTGGGTGGAAGG
TCATGGGCCGCGGCCCGAGACCTCCAACCCCGCGCCGTTTCGCCCGGTGATGCTGGCCCACGCCATCGAGGAAGCCAATT
TCGCCGACCTTGCCCCCGGCGATTTCAGCGCCGAATGGAAGTGGGACGGCATCCGCGTGCAGGCGGTGGCCGGCACCGGG
GCGGATGGGGTGCGGGCGGTGCGGCTTTATTCCCGCACCGGTGAGGACATCTCCGAGGCTTTTCCCGATCTGGCGGACGC
CATCGCCTTTAACGGCGCCATGGACGGGGAGTTGCTGATCGTCCGCGCGGGGCGGGTGGAGCCGTTCAACGTGCTCCAGC
AGCGGCTCAACCGCAAAAGCGTGACGGTGAAGATGCTGGCGGAATTTCCCGCCCACATCCGTGCCTACGATTTGCTGGTC
GATGGCGACGAGGACCTGCGCGCCCTGCCCTTCACCGCGCGGCGGGCGCGGCTGGAGGCGCTGGTGACCCGGCTGTCGTC
GCCGCGCATCGACCTCTCCCCGCTGGTGCCCTTCGCCGGCTGGGATGACCTCACCCGCGCCCGCGCGGACCCCGCATCCG
CCGGCGCGGGGCCGGACGCCGGCGCGGTGGAAGGGGTGATGATCAAGCGCGGCGACAGTCCCTACCTGCCCGGCCGTCCC
AAGGGGCCGTGGTGGAAATGGAAGCGCGATCCGCACACGGTGGACGCCGTGCTCATGTATGCCCAGCGCGGCCACGGCAA
GCGCTCGTCCTTTTATTCCGACTACACCTTCGGGGTGTGGACGCAGGGCGAGGAGGGCGATGTTCTGGTGCCCGTGGGCA
AGGCCTATTTCGGCTTCACCGACGAGGAGCTGAAGCTGATCGACGCCTTCGTGCGGCGCGCCACCATCAACCGCTTCGGC
CCGGTGCGGGAAGTGGTGCATGAGAAGGACGAGGGGCTGGTGCTGGAAGTGGCCTTCGAGGGCCTCGCCCGCTCCACCCG
CCACCGCTCCGGCATCGCCATGCGCTTCCCCCGCATCGCGCGCCTCAGGTGGGACAAGCCGCCGGGCGAGGCCGACCGGC
TGGAGACACTGGAGGCGCTGCTGAGGTAG

Upstream 100 bases:

>100_bases
AGACCCGCCAATTGCGTGCCCGCCCGCTCCACATGGTGGGCTATGGCGAGGAGGACGAGGAGGCGGCTCCCACTGAAGGC
GCAGCGCCGGGGGCTGCGCC

Downstream 100 bases:

>100_bases
GGTGACTTTTATACCATCGGCCCCGGTCTTCGACCGAAGCCGAGAGGGTGTCGCTCAGGCGCCGCGCGGGCTTCATGCCA
AGGGCCGACGAGGCACACTC

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] 1 [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNRFAALLDRMSYEAGRNAKIRLMADYFRTTPDPERGFALAALTGALSFANAKPGVVRALIMERADPVLFEMSYDYVGDL
SETVALMWPRLEGAPTHAPLLSEIVHGLSTLSRSTLPRRLADWLDGLDETGRWALLKLITGAMRVGASARLAKTALASLG
SVTPDEVELVWPGLAPPYEELFAWVEGHGPRPETSNPAPFRPVMLAHAIEEANFADLAPGDFSAEWKWDGIRVQAVAGTG
ADGVRAVRLYSRTGEDISEAFPDLADAIAFNGAMDGELLIVRAGRVEPFNVLQQRLNRKSVTVKMLAEFPAHIRAYDLLV
DGDEDLRALPFTARRARLEALVTRLSSPRIDLSPLVPFAGWDDLTRARADPASAGAGPDAGAVEGVMIKRGDSPYLPGRP
KGPWWKWKRDPHTVDAVLMYAQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDEELKLIDAFVRRATINRFG
PVREVVHEKDEGLVLEVAFEGLARSTRHRSGIAMRFPRIARLRWDKPPGEADRLETLEALLR

Sequences:

>Translated_542_residues
MNRFAALLDRMSYEAGRNAKIRLMADYFRTTPDPERGFALAALTGALSFANAKPGVVRALIMERADPVLFEMSYDYVGDL
SETVALMWPRLEGAPTHAPLLSEIVHGLSTLSRSTLPRRLADWLDGLDETGRWALLKLITGAMRVGASARLAKTALASLG
SVTPDEVELVWPGLAPPYEELFAWVEGHGPRPETSNPAPFRPVMLAHAIEEANFADLAPGDFSAEWKWDGIRVQAVAGTG
ADGVRAVRLYSRTGEDISEAFPDLADAIAFNGAMDGELLIVRAGRVEPFNVLQQRLNRKSVTVKMLAEFPAHIRAYDLLV
DGDEDLRALPFTARRARLEALVTRLSSPRIDLSPLVPFAGWDDLTRARADPASAGAGPDAGAVEGVMIKRGDSPYLPGRP
KGPWWKWKRDPHTVDAVLMYAQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDEELKLIDAFVRRATINRFG
PVREVVHEKDEGLVLEVAFEGLARSTRHRSGIAMRFPRIARLRWDKPPGEADRLETLEALLR
>Mature_542_residues
MNRFAALLDRMSYEAGRNAKIRLMADYFRTTPDPERGFALAALTGALSFANAKPGVVRALIMERADPVLFEMSYDYVGDL
SETVALMWPRLEGAPTHAPLLSEIVHGLSTLSRSTLPRRLADWLDGLDETGRWALLKLITGAMRVGASARLAKTALASLG
SVTPDEVELVWPGLAPPYEELFAWVEGHGPRPETSNPAPFRPVMLAHAIEEANFADLAPGDFSAEWKWDGIRVQAVAGTG
ADGVRAVRLYSRTGEDISEAFPDLADAIAFNGAMDGELLIVRAGRVEPFNVLQQRLNRKSVTVKMLAEFPAHIRAYDLLV
DGDEDLRALPFTARRARLEALVTRLSSPRIDLSPLVPFAGWDDLTRARADPASAGAGPDAGAVEGVMIKRGDSPYLPGRP
KGPWWKWKRDPHTVDAVLMYAQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDEELKLIDAFVRRATINRFG
PVREVVHEKDEGLVLEVAFEGLARSTRHRSGIAMRFPRIARLRWDKPPGEADRLETLEALLR

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71985269, Length=463, Percent_Identity=28.0777537796976, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320038, Length=392, Percent_Identity=26.2755102040816, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 59822; Mature: 59822

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFAALLDRMSYEAGRNAKIRLMADYFRTTPDPERGFALAALTGALSFANAKPGVVRAL
CCHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCHHHCEEHHHHHHHHHHCCCCCHHHHHH
IMERADPVLFEMSYDYVGDLSETVALMWPRLEGAPTHAPLLSEIVHGLSTLSRSTLPRRL
HHHCCCCEEEEECCHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADWLDGLDETGRWALLKLITGAMRVGASARLAKTALASLGSVTPDEVELVWPGLAPPYEE
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
LFAWVEGHGPRPETSNPAPFRPVMLAHAIEEANFADLAPGDFSAEWKWDGIRVQAVAGTG
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEEEECCC
ADGVRAVRLYSRTGEDISEAFPDLADAIAFNGAMDGELLIVRAGRVEPFNVLQQRLNRKS
CCCHHEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHH
VTVKMLAEFPAHIRAYDLLVDGDEDLRALPFTARRARLEALVTRLSSPRIDLSPLVPFAG
HHHHHHHHCCHHHEEEEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
WDDLTRARADPASAGAGPDAGAVEGVMIKRGDSPYLPGRPKGPWWKWKRDPHTVDAVLMY
CHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDEELKLIDAFVRRATINRFG
HHHCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHH
PVREVVHEKDEGLVLEVAFEGLARSTRHRSGIAMRFPRIARLRWDKPPGEADRLETLEAL
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCEECCCHHHHEECCCCCCHHHHHHHHHHH
LR
HC
>Mature Secondary Structure
MNRFAALLDRMSYEAGRNAKIRLMADYFRTTPDPERGFALAALTGALSFANAKPGVVRAL
CCHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCHHHCEEHHHHHHHHHHCCCCCHHHHHH
IMERADPVLFEMSYDYVGDLSETVALMWPRLEGAPTHAPLLSEIVHGLSTLSRSTLPRRL
HHHCCCCEEEEECCHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADWLDGLDETGRWALLKLITGAMRVGASARLAKTALASLGSVTPDEVELVWPGLAPPYEE
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
LFAWVEGHGPRPETSNPAPFRPVMLAHAIEEANFADLAPGDFSAEWKWDGIRVQAVAGTG
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCEEEEEEECCC
ADGVRAVRLYSRTGEDISEAFPDLADAIAFNGAMDGELLIVRAGRVEPFNVLQQRLNRKS
CCCHHEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHH
VTVKMLAEFPAHIRAYDLLVDGDEDLRALPFTARRARLEALVTRLSSPRIDLSPLVPFAG
HHHHHHHHCCHHHEEEEEEEECCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
WDDLTRARADPASAGAGPDAGAVEGVMIKRGDSPYLPGRPKGPWWKWKRDPHTVDAVLMY
CHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDEELKLIDAFVRRATINRFG
HHHCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHH
PVREVVHEKDEGLVLEVAFEGLARSTRHRSGIAMRFPRIARLRWDKPPGEADRLETLEAL
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCEECCCHHHHEECCCCCCHHHHHHHHHHH
LR
HC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA