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The map label for this gene is dinF [H]

Identifier: 154245414

GI number: 154245414

Start: 1677252

End: 1678577

Strand: Direct

Name: dinF [H]

Synonym: Xaut_1467

Alternate gene names: 154245414

Gene position: 1677252-1678577 (Clockwise)

Preceding gene: 154245413

Following gene: 154245416

Centisome position: 31.59

GC content: 72.1

Gene sequence:

>1326_bases
ATGGCCCTCGCCGCTGCTGACGGTCGGGTCACGCACGCTCGGGTGCTTGCCATCGCGCTGCCCATGACGGTGGCGCACCT
GACCACGCCGCTGCTCGGCATCGTGGATGCGGCGGTGGTGGGGCGGCTGGGGGATGCGGCGCTGCTGGGCGGGGTGGCGC
TGGCCGCCGTTATCTTCGACATGCTGTTCTGGGTGTTCGGCTTCCTGCGCATGGGCACGGTGGGCCTCGCCGCCCAGGCG
GTCGGTCGGCGCGACGGCGTGGAAGAGCGTGCCGTGCTCGCCCGCGCTCTGCTGCTCGCCGGCGCCTTGGGTCTGGTGCT
CATCGCCCTGCAGGCGCCCATCGCCTATGCCGCCCTCGGCCTTGCCGGGGCGAGCGAGGAGGTGAACGCGGCGGTGCGCG
CCTATTATGCCGTGCGCATCTACGCCGCGCCCTTCACCCTGGCCAATTATGTGGTGCTGGGCTGGCTGGTGGGCCTCGGC
CGCACCGGCCGGGCGCTGGCGCTGCAGGTGGGCATGAACCTGCTCAACATGGCGCTCACTGCCGTCCTGGTGCTCGGCGC
CGGGTGGGGCGTCGCGGGGGCCGCCGCCGGCACGCTGATGGCGGAGATCGCCGGCACCGCGGCGGGGCTGCTCCTGTGCC
TGAGCATGCTCGGCGGCGCGGTGGCTCTGCCGCGCGGGGTGCTGTTCAACCGGGCGCGGCTCGCCGAATCGTTCCTGCTC
AATCGCGACATCATGATCCGCACCGCGGCGCTGATGTTCGCCTTCTCCTTCTTCGCGGCGCAGGGCGCGCGGGCGGGGGA
CGTGACGCTGGCCGCCAACGCCGTGCTCCAGAACATGGTGATGGTGGCCGCCTATTTCCTCGACGGCTTCGCTACCGCCG
CTGAGCAGATCTGCGGCGCGGCGGTGGGCGGCCGCCGGCGGGCGGACTTTGCCGCCGGAGTGCGGCTGTGCCTCATCTGG
GGGCTCGTCTTCGCGCTGGTGGCCTGCGCGCTCTATCTCGCCATCGGCCCGGCCATCGTGGATGCCATGACCACGAGCGA
GGAGGTGCGCGCGGCGGCCCGCGATTTCCTCATCTATGCCGCGCTGCTGCCGGTGGCGGGCGTCGCCGCCTATGCCTTCG
ACGGGGTCTATATCGGCGCCCTGTGGTCGCGCGACATGCGCAACCTGATGCTGTGCGCTCTCGCCGTCTATCTTGCCGCC
TGGTGGGGACTGCGGGGGCTGGGCAATCACGGCCTGTGGCTGGCCTTCCTCGCCTTTCTCATCGCCCGGGGAGCGTTCCA
GGCGCTGCGCCTGCCGGCGCTGGAGCGCCGCACCTTCGGGGCGTGA

Upstream 100 bases:

>100_bases
CGAGGCGGTGGAGCGGCTGTGGCGCTATTTCCTGCTCGGCGCCGTGGTTGTCATCCCGCTCTGGCTCATTTTGCGCGTCC
TCGGCCGGCGCTGATCCCCG

Downstream 100 bases:

>100_bases
TCAGGCCATGTCCGGAAAGAGGTGCGCGCCGTCCGGCCCCAGCGGCAGGTCCTTCACCCACAACACGGCGGTGAGCGGCA
ACGGGCCGTAAAGGTGGGGG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MALAAADGRVTHARVLAIALPMTVAHLTTPLLGIVDAAVVGRLGDAALLGGVALAAVIFDMLFWVFGFLRMGTVGLAAQA
VGRRDGVEERAVLARALLLAGALGLVLIALQAPIAYAALGLAGASEEVNAAVRAYYAVRIYAAPFTLANYVVLGWLVGLG
RTGRALALQVGMNLLNMALTAVLVLGAGWGVAGAAAGTLMAEIAGTAAGLLLCLSMLGGAVALPRGVLFNRARLAESFLL
NRDIMIRTAALMFAFSFFAAQGARAGDVTLAANAVLQNMVMVAAYFLDGFATAAEQICGAAVGGRRRADFAAGVRLCLIW
GLVFALVACALYLAIGPAIVDAMTTSEEVRAAARDFLIYAALLPVAGVAAYAFDGVYIGALWSRDMRNLMLCALAVYLAA
WWGLRGLGNHGLWLAFLAFLIARGAFQALRLPALERRTFGA

Sequences:

>Translated_441_residues
MALAAADGRVTHARVLAIALPMTVAHLTTPLLGIVDAAVVGRLGDAALLGGVALAAVIFDMLFWVFGFLRMGTVGLAAQA
VGRRDGVEERAVLARALLLAGALGLVLIALQAPIAYAALGLAGASEEVNAAVRAYYAVRIYAAPFTLANYVVLGWLVGLG
RTGRALALQVGMNLLNMALTAVLVLGAGWGVAGAAAGTLMAEIAGTAAGLLLCLSMLGGAVALPRGVLFNRARLAESFLL
NRDIMIRTAALMFAFSFFAAQGARAGDVTLAANAVLQNMVMVAAYFLDGFATAAEQICGAAVGGRRRADFAAGVRLCLIW
GLVFALVACALYLAIGPAIVDAMTTSEEVRAAARDFLIYAALLPVAGVAAYAFDGVYIGALWSRDMRNLMLCALAVYLAA
WWGLRGLGNHGLWLAFLAFLIARGAFQALRLPALERRTFGA
>Mature_440_residues
ALAAADGRVTHARVLAIALPMTVAHLTTPLLGIVDAAVVGRLGDAALLGGVALAAVIFDMLFWVFGFLRMGTVGLAAQAV
GRRDGVEERAVLARALLLAGALGLVLIALQAPIAYAALGLAGASEEVNAAVRAYYAVRIYAAPFTLANYVVLGWLVGLGR
TGRALALQVGMNLLNMALTAVLVLGAGWGVAGAAAGTLMAEIAGTAAGLLLCLSMLGGAVALPRGVLFNRARLAESFLLN
RDIMIRTAALMFAFSFFAAQGARAGDVTLAANAVLQNMVMVAAYFLDGFATAAEQICGAAVGGRRRADFAAGVRLCLIWG
LVFALVACALYLAIGPAIVDAMTTSEEVRAAARDFLIYAALLPVAGVAAYAFDGVYIGALWSRDMRNLMLCALAVYLAAW
WGLRGLGNHGLWLAFLAFLIARGAFQALRLPALERRTFGA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=443, Percent_Identity=37.4717832957111, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 45714; Mature: 45583

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAAADGRVTHARVLAIALPMTVAHLTTPLLGIVDAAVVGRLGDAALLGGVALAAVIFD
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MLFWVFGFLRMGTVGLAAQAVGRRDGVEERAVLARALLLAGALGLVLIALQAPIAYAALG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGASEEVNAAVRAYYAVRIYAAPFTLANYVVLGWLVGLGRTGRALALQVGMNLLNMALT
CCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AVLVLGAGWGVAGAAAGTLMAEIAGTAAGLLLCLSMLGGAVALPRGVLFNRARLAESFLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
NRDIMIRTAALMFAFSFFAAQGARAGDVTLAANAVLQNMVMVAAYFLDGFATAAEQICGA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGGRRRADFAAGVRLCLIWGLVFALVACALYLAIGPAIVDAMTTSEEVRAAARDFLIYA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALLPVAGVAAYAFDGVYIGALWSRDMRNLMLCALAVYLAAWWGLRGLGNHGLWLAFLAFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IARGAFQALRLPALERRTFGA
HHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
ALAAADGRVTHARVLAIALPMTVAHLTTPLLGIVDAAVVGRLGDAALLGGVALAAVIFD
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MLFWVFGFLRMGTVGLAAQAVGRRDGVEERAVLARALLLAGALGLVLIALQAPIAYAALG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGASEEVNAAVRAYYAVRIYAAPFTLANYVVLGWLVGLGRTGRALALQVGMNLLNMALT
CCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AVLVLGAGWGVAGAAAGTLMAEIAGTAAGLLLCLSMLGGAVALPRGVLFNRARLAESFLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
NRDIMIRTAALMFAFSFFAAQGARAGDVTLAANAVLQNMVMVAAYFLDGFATAAEQICGA
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGGRRRADFAAGVRLCLIWGLVFALVACALYLAIGPAIVDAMTTSEEVRAAARDFLIYA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALLPVAGVAAYAFDGVYIGALWSRDMRNLMLCALAVYLAAWWGLRGLGNHGLWLAFLAFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IARGAFQALRLPALERRTFGA
HHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]