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The map label for this gene is prmA [H]

Identifier: 154245371

GI number: 154245371

Start: 1631364

End: 1632290

Strand: Reverse

Name: prmA [H]

Synonym: Xaut_1424

Alternate gene names: 154245371

Gene position: 1632290-1631364 (Counterclockwise)

Preceding gene: 154245372

Following gene: 154245369

Centisome position: 30.75

GC content: 70.77

Gene sequence:

>927_bases
ATGATTGCGCCCCCCATGCTCGAAGGCCTCCCCCCCAACGACGCCACCCATGTGATGCGGGTGGAAGCTTCCCGCGTCGC
CGCCCAGCGCATCTCCGACATGATTTCCGAGACGTTCGATCCCGCCGAGGTGGCGGTGGCCAATTTCGAGCGCACGGACA
ATGACTGGGTGGTGGAAGTCTATGCCGGTGCGGCCTTCGACCCCGAACGGCTGCGGGAGATGGTGGAGATCGCCGCCGGG
CCGGAGATCGCCAGCACGGTCACCTTCGGCGACGTGGAGGAGAAGGACTGGGTGGCCGCGAGCCTGGAAGGCCTCGCGCC
GGTGCGCGTGGGCACCTTCGTGGTCCATGGCGGCCATGATCGCGGGCGCGTGGGGCCGAACCTCATCGGTATCGAGATCG
AGGCGGCACTCGCATTCGGTACCGGTCATCACGGCACCACCCAGGGCTGCCTCCACGCCATCACCGATGCCGCGCGGCGC
GGCGCTCCGCGGCGCGTGCTGGATGTGGGAACGGGAACCGGCGTGCTCGCCATCGCGGCGGACCGGCTGTTTCATACCCA
TGTGGTGGGCAGCGACATCGACGCCATCGCCGTGCGCACCGCCCGCGCCAACGCCAAGGCCAACAAGGCGCCGGCCGTGC
AGATGATCCATGCGGCCGGGGCCGGGGCGCGCGTGCTGCGGGTGGGCGGTCCCTACGACCTGATCCTCGCCAACATCCTC
CTGCCGCCGCTGAAGCGGCTGGCGCGCCCACTGCGCCGGCTGCTGGCGCCGGGCGGCCGTATCGTGCTGTCGGGATTGTT
GTCGGCACAGGTACCGGCGGCGCTCGCGGCCTATCGCGCCCAGGGGCTTCGCCTGGTGTCGCAGCGCCATATCGAAGGCT
GGGCGACGCTCACCCTCGCCGCGGATGCGGGGCGGCCCCTGCGCTGA

Upstream 100 bases:

>100_bases
AGCTGCTGGATGCGGCCGACAAGCGCCTCTACGCGGCGAAGGCGGCCGGGCGGAACCGCGCAGCGGGCGGACCCGAAGCC
GACGCCCTCAAGATGAACGG

Downstream 100 bases:

>100_bases
AGACCGGACGGTCAAATGCAAAAGCCGCCCGCGCCGAACAGGTGCGAGCGGTCAATCCGGCAGCGGTGACCATATTGAAT
AAAGGCGAGAAGGCAGCGCA

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIAPPMLEGLPPNDATHVMRVEASRVAAQRISDMISETFDPAEVAVANFERTDNDWVVEVYAGAAFDPERLREMVEIAAG
PEIASTVTFGDVEEKDWVAASLEGLAPVRVGTFVVHGGHDRGRVGPNLIGIEIEAALAFGTGHHGTTQGCLHAITDAARR
GAPRRVLDVGTGTGVLAIAADRLFHTHVVGSDIDAIAVRTARANAKANKAPAVQMIHAAGAGARVLRVGGPYDLILANIL
LPPLKRLARPLRRLLAPGGRIVLSGLLSAQVPAALAAYRAQGLRLVSQRHIEGWATLTLAADAGRPLR

Sequences:

>Translated_308_residues
MIAPPMLEGLPPNDATHVMRVEASRVAAQRISDMISETFDPAEVAVANFERTDNDWVVEVYAGAAFDPERLREMVEIAAG
PEIASTVTFGDVEEKDWVAASLEGLAPVRVGTFVVHGGHDRGRVGPNLIGIEIEAALAFGTGHHGTTQGCLHAITDAARR
GAPRRVLDVGTGTGVLAIAADRLFHTHVVGSDIDAIAVRTARANAKANKAPAVQMIHAAGAGARVLRVGGPYDLILANIL
LPPLKRLARPLRRLLAPGGRIVLSGLLSAQVPAALAAYRAQGLRLVSQRHIEGWATLTLAADAGRPLR
>Mature_308_residues
MIAPPMLEGLPPNDATHVMRVEASRVAAQRISDMISETFDPAEVAVANFERTDNDWVVEVYAGAAFDPERLREMVEIAAG
PEIASTVTFGDVEEKDWVAASLEGLAPVRVGTFVVHGGHDRGRVGPNLIGIEIEAALAFGTGHHGTTQGCLHAITDAARR
GAPRRVLDVGTGTGVLAIAADRLFHTHVVGSDIDAIAVRTARANAKANKAPAVQMIHAAGAGARVLRVGGPYDLILANIL
LPPLKRLARPLRRLLAPGGRIVLSGLLSAQVPAALAAYRAQGLRLVSQRHIEGWATLTLAADAGRPLR

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=207, Percent_Identity=31.4009661835749, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32470; Mature: 32470

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPPMLEGLPPNDATHVMRVEASRVAAQRISDMISETFDPAEVAVANFERTDNDWVVEV
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEE
YAGAAFDPERLREMVEIAAGPEIASTVTFGDVEEKDWVAASLEGLAPVRVGTFVVHGGHD
EECCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCCHHHHHHCCCCCEEEEEEEEECCCC
RGRVGPNLIGIEIEAALAFGTGHHGTTQGCLHAITDAARRGAPRRVLDVGTGTGVLAIAA
CCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHH
DRLFHTHVVGSDIDAIAVRTARANAKANKAPAVQMIHAAGAGARVLRVGGPYDLILANIL
HHHHHHHHCCCCCHHHEEEEHHCCCCCCCCCHHHEEECCCCCCEEEEECCCHHHHHHHHH
LPPLKRLARPLRRLLAPGGRIVLSGLLSAQVPAALAAYRAQGLRLVSQRHIEGWATLTLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
ADAGRPLR
ECCCCCCC
>Mature Secondary Structure
MIAPPMLEGLPPNDATHVMRVEASRVAAQRISDMISETFDPAEVAVANFERTDNDWVVEV
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEE
YAGAAFDPERLREMVEIAAGPEIASTVTFGDVEEKDWVAASLEGLAPVRVGTFVVHGGHD
EECCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCCHHHHHHCCCCCEEEEEEEEECCCC
RGRVGPNLIGIEIEAALAFGTGHHGTTQGCLHAITDAARRGAPRRVLDVGTGTGVLAIAA
CCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHH
DRLFHTHVVGSDIDAIAVRTARANAKANKAPAVQMIHAAGAGARVLRVGGPYDLILANIL
HHHHHHHHCCCCCHHHEEEEHHCCCCCCCCCHHHEEECCCCCCEEEEECCCHHHHHHHHH
LPPLKRLARPLRRLLAPGGRIVLSGLLSAQVPAALAAYRAQGLRLVSQRHIEGWATLTLA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
ADAGRPLR
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]