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The map label for this gene is paaG [C]

Identifier: 154245348

GI number: 154245348

Start: 1605836

End: 1606648

Strand: Direct

Name: paaG [C]

Synonym: Xaut_1401

Alternate gene names: 154245348

Gene position: 1605836-1606648 (Clockwise)

Preceding gene: 154245347

Following gene: 154245349

Centisome position: 30.25

GC content: 69.99

Gene sequence:

>813_bases
ATGAGCGCCCCCACCAGCGCCGCCGTCGACGAACACCCCATCCGCCTCGACATTGCCGAGGGCATAGCCCGCATCCGCTT
CAATCGCCCCCATGTGCTGAACGCCATCAACGATGCGGCGGTGCTGGCTTTAAAGGCGGCGGTGGACCAGGTGGCGAAGG
ACGAGAGCGTCCGGGTGGTGGTGCTGTCGGGGGAAGGGCGGGCCTTCATGGCCGGCGGCGACGTGGGCCGCTTCCATGAG
GCCGGCCGCGACGCGCCGAAGGTGGTGAGCGCCATCATCGATCCGTTTCACCATGCCATCGTCTCGCTCGCCGCCATGCC
GGCGCCGGTGATCGCGTGCCTCCACGGCGCGGTGGCGGGGGCCGGGGTCTCGGTGGCGCTGGCTGCGGACCTTGCCATCG
CCGCCGACGACATCAAGATGACCCTGGCCTACACCCGCATCGGCACCTCGCCGGACGGGTCGTCCACCTTCTCGCTGCCG
CGGGTGGTGGGGCTGCGCAAGGCCATGGAGATCGCGCTGCTCTCCGACACTGTCGAGGCGGCGGAAGCGCTGCGGCTGGG
GCTGGTGAACAAGGTGGTGCCGGCGGCGGACCTTCAGGCCGAGACGGATGCGCTGGCGAAACGCCTCGCCGCCGGGCCGA
CGCTGGCCTATGGCCGCATCAAGCACCTGCTGCGCGCCTCCTTCAACCACAGCCTGTCGGACCAGCTTAACGCCGAGCGC
GATGCCTTCATCGCCAGCGCCGGCACCCACGATTTCGCCGAGGGCGCTACCGCTTTCGTGGAAAAGCGCGCGCCCCGCTT
CGAGGGACGGTAG

Upstream 100 bases:

>100_bases
GTGGCGATGCTCCGGCTTTGGCAGCTTGGCGGTCCCCAGCCGGATACGCCTGCCGCACCCGCGTGCGGGCCGAGCCGATA
ACGCCCGAGGAACGCCCCCA

Downstream 100 bases:

>100_bases
CCCGTCCGCACGATCCCCAAGCCTTGTCGCAGGCCTTGCGTTGCCCGCCGGCATTCGTCGGCGGGCAGGGGCCATAAACC
AAAATACACATGAAAAATTT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSAPTSAAVDEHPIRLDIAEGIARIRFNRPHVLNAINDAAVLALKAAVDQVAKDESVRVVVLSGEGRAFMAGGDVGRFHE
AGRDAPKVVSAIIDPFHHAIVSLAAMPAPVIACLHGAVAGAGVSVALAADLAIAADDIKMTLAYTRIGTSPDGSSTFSLP
RVVGLRKAMEIALLSDTVEAAEALRLGLVNKVVPAADLQAETDALAKRLAAGPTLAYGRIKHLLRASFNHSLSDQLNAER
DAFIASAGTHDFAEGATAFVEKRAPRFEGR

Sequences:

>Translated_270_residues
MSAPTSAAVDEHPIRLDIAEGIARIRFNRPHVLNAINDAAVLALKAAVDQVAKDESVRVVVLSGEGRAFMAGGDVGRFHE
AGRDAPKVVSAIIDPFHHAIVSLAAMPAPVIACLHGAVAGAGVSVALAADLAIAADDIKMTLAYTRIGTSPDGSSTFSLP
RVVGLRKAMEIALLSDTVEAAEALRLGLVNKVVPAADLQAETDALAKRLAAGPTLAYGRIKHLLRASFNHSLSDQLNAER
DAFIASAGTHDFAEGATAFVEKRAPRFEGR
>Mature_269_residues
SAPTSAAVDEHPIRLDIAEGIARIRFNRPHVLNAINDAAVLALKAAVDQVAKDESVRVVVLSGEGRAFMAGGDVGRFHEA
GRDAPKVVSAIIDPFHHAIVSLAAMPAPVIACLHGAVAGAGVSVALAADLAIAADDIKMTLAYTRIGTSPDGSSTFSLPR
VVGLRKAMEIALLSDTVEAAEALRLGLVNKVVPAADLQAETDALAKRLAAGPTLAYGRIKHLLRASFNHSLSDQLNAERD
AFIASAGTHDFAEGATAFVEKRAPRFEGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=31.0483870967742, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI260274832, Length=209, Percent_Identity=28.2296650717703, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI45643119, Length=209, Percent_Identity=28.2296650717703, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI260275230, Length=209, Percent_Identity=28.2296650717703, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31542718, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI70995211, Length=252, Percent_Identity=26.5873015873016, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502327, Length=262, Percent_Identity=29.3893129770992, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4757968, Length=265, Percent_Identity=24.1509433962264, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=265, Percent_Identity=24.1509433962264, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI25453481, Length=235, Percent_Identity=24.6808510638298, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI51538573, Length=235, Percent_Identity=24.6808510638298, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4757966, Length=210, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI51538581, Length=210, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI221136756, Length=239, Percent_Identity=24.2677824267782, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136753, Length=239, Percent_Identity=24.2677824267782, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221307494, Length=239, Percent_Identity=24.2677824267782, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=27.6041666666667, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI37594469, Length=184, Percent_Identity=25, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI37594471, Length=184, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=34.6456692913386, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=31.496062992126, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI221142681, Length=255, Percent_Identity=29.0196078431373, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=27.6679841897233, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788682, Length=199, Percent_Identity=30.1507537688442, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=255, Percent_Identity=34.5098039215686, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=29.8804780876494, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17560910, Length=242, Percent_Identity=27.6859504132231, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=26.0536398467433, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=252, Percent_Identity=25.3968253968254, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=196, Percent_Identity=29.5918367346939, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=222, Percent_Identity=26.5765765765766, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=265, Percent_Identity=24.5283018867925, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=228, Percent_Identity=25, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=188, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=188, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=188, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=25.3846153846154, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=215, Percent_Identity=28.8372093023256, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129971, Length=268, Percent_Identity=32.089552238806, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24653477, Length=268, Percent_Identity=32.089552238806, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=32.0610687022901, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654903, Length=238, Percent_Identity=25.2100840336134, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=22.1774193548387, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357171, Length=250, Percent_Identity=25.6, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28147; Mature: 28016

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTSAAVDEHPIRLDIAEGIARIRFNRPHVLNAINDAAVLALKAAVDQVAKDESVRVV
CCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VLSGEGRAFMAGGDVGRFHEAGRDAPKVVSAIIDPFHHAIVSLAAMPAPVIACLHGAVAG
EEECCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
AGVSVALAADLAIAADDIKMTLAYTRIGTSPDGSSTFSLPRVVGLRKAMEIALLSDTVEA
CCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEALRLGLVNKVVPAADLQAETDALAKRLAAGPTLAYGRIKHLLRASFNHSLSDQLNAER
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHH
DAFIASAGTHDFAEGATAFVEKRAPRFEGR
HHHEECCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAPTSAAVDEHPIRLDIAEGIARIRFNRPHVLNAINDAAVLALKAAVDQVAKDESVRVV
CCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VLSGEGRAFMAGGDVGRFHEAGRDAPKVVSAIIDPFHHAIVSLAAMPAPVIACLHGAVAG
EEECCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
AGVSVALAADLAIAADDIKMTLAYTRIGTSPDGSSTFSLPRVVGLRKAMEIALLSDTVEA
CCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEALRLGLVNKVVPAADLQAETDALAKRLAAGPTLAYGRIKHLLRASFNHSLSDQLNAER
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHH
DAFIASAGTHDFAEGATAFVEKRAPRFEGR
HHHEECCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA