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The map label for this gene is cysH [H]

Identifier: 154245342

GI number: 154245342

Start: 1599356

End: 1600120

Strand: Reverse

Name: cysH [H]

Synonym: Xaut_1395

Alternate gene names: 154245342

Gene position: 1600120-1599356 (Counterclockwise)

Preceding gene: 154245343

Following gene: 154245341

Centisome position: 30.14

GC content: 69.28

Gene sequence:

>765_bases
ATGACAGCCAGCCACAGCGCCAGCCTCCCCGCCACTCCTTTCGACCAGCCCTCGACCGGCGCCCCCCTTGGCGCAGGATC
CGGCTTCGACGCGGCGGCGCTCAATGCGAAGCTCAGGTCGGCCGCGCCGCTGGAGATCATCGCGGCGGGGCTTGCCGCCT
TTCCCGGCCACATCGCCGCCGTCTCGTCCTTCGGAACGGAATCGGCGGTGCTGCTGCACATGATCGCGCAGGTGGACAAG
GCGACGCCGGTGCTCTTCCTCGACACCGGCCACCTGTTCGAGGAAACGCTGGCCTATCGCGACACCCTTATTGCGTGCCT
CGGGCTGACGCAGGTCCTCACCTTCTCCCCGGATCCGGCGGCGCTCGCCGCGCGCGATCCCGAAAACGGCCTGTGGGCGG
ATGACCCGGATGCCTGCTGCGGCCTGCGCAAGGTGGAGCCGCTGGCCCGGGCGCTCGGCCCCTATGCGGCCTGGATCAAC
GGCCGCAAGCGCTACCAGGCGTCGACCCGCGCCGACATTCCCTTCGTGGAGGAGGACGGCGCGCGGGTGAAATTCAACCC
GCTGGCGGCGCTCGGTCGCGACGACCTGCTCGCCTACATGGATGCCCACGCGCTGCCGCGGCACCCCATGGAACAGTTCG
GCTTTCCCTCCATCGGCTGCATGCCCTGCACCTCGCGGGTGAAGCCGGGGGAGGACCCGCGCGCCGGCCGCTGGCGCGGA
AAGTCCAAGACCGAATGCGGTATCCATATTGGCGATGGGAAATAA

Upstream 100 bases:

>100_bases
GCGGTTGCCACCTATTCGGTCTTCTACCAGCCCACGGGCGACCATCGCCCCACCGTGCGCGACGCTCGCACCGCGCCGGC
GGCCACAGGGGGATAGTCCC

Downstream 100 bases:

>100_bases
TTTAATTCCATCGAATTTGTGATAAAAGGTGTTGACCCTTCGCGAGGCCAGTGCCATCGTTTGTTTTATCGAACAGACGA
TCCGTTTGACGGATGAACTT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTASHSASLPATPFDQPSTGAPLGAGSGFDAAALNAKLRSAAPLEIIAAGLAAFPGHIAAVSSFGTESAVLLHMIAQVDK
ATPVLFLDTGHLFEETLAYRDTLIACLGLTQVLTFSPDPAALAARDPENGLWADDPDACCGLRKVEPLARALGPYAAWIN
GRKRYQASTRADIPFVEEDGARVKFNPLAALGRDDLLAYMDAHALPRHPMEQFGFPSIGCMPCTSRVKPGEDPRAGRWRG
KSKTECGIHIGDGK

Sequences:

>Translated_254_residues
MTASHSASLPATPFDQPSTGAPLGAGSGFDAAALNAKLRSAAPLEIIAAGLAAFPGHIAAVSSFGTESAVLLHMIAQVDK
ATPVLFLDTGHLFEETLAYRDTLIACLGLTQVLTFSPDPAALAARDPENGLWADDPDACCGLRKVEPLARALGPYAAWIN
GRKRYQASTRADIPFVEEDGARVKFNPLAALGRDDLLAYMDAHALPRHPMEQFGFPSIGCMPCTSRVKPGEDPRAGRWRG
KSKTECGIHIGDGK
>Mature_253_residues
TASHSASLPATPFDQPSTGAPLGAGSGFDAAALNAKLRSAAPLEIIAAGLAAFPGHIAAVSSFGTESAVLLHMIAQVDKA
TPVLFLDTGHLFEETLAYRDTLIACLGLTQVLTFSPDPAALAARDPENGLWADDPDACCGLRKVEPLARALGPYAAWING
RKRYQASTRADIPFVEEDGARVKFNPLAALGRDDLLAYMDAHALPRHPMEQFGFPSIGCMPCTSRVKPGEDPRAGRWRGK
SKTECGIHIGDGK

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=226, Percent_Identity=31.4159292035398, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325425, Length=225, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26819; Mature: 26688

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASHSASLPATPFDQPSTGAPLGAGSGFDAAALNAKLRSAAPLEIIAAGLAAFPGHIAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
VSSFGTESAVLLHMIAQVDKATPVLFLDTGHLFEETLAYRDTLIACLGLTQVLTFSPDPA
HHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
ALAARDPENGLWADDPDACCGLRKVEPLARALGPYAAWINGRKRYQASTRADIPFVEEDG
EEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHCHHHHHHCCHHHHCCCCCCCCCEEECCC
ARVKFNPLAALGRDDLLAYMDAHALPRHPMEQFGFPSIGCMPCTSRVKPGEDPRAGRWRG
CEEEECHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KSKTECGIHIGDGK
CCCCCCCEEECCCC
>Mature Secondary Structure 
TASHSASLPATPFDQPSTGAPLGAGSGFDAAALNAKLRSAAPLEIIAAGLAAFPGHIAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
VSSFGTESAVLLHMIAQVDKATPVLFLDTGHLFEETLAYRDTLIACLGLTQVLTFSPDPA
HHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
ALAARDPENGLWADDPDACCGLRKVEPLARALGPYAAWINGRKRYQASTRADIPFVEEDG
EEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHCHHHHHHCCHHHHCCCCCCCCCEEECCC
ARVKFNPLAALGRDDLLAYMDAHALPRHPMEQFGFPSIGCMPCTSRVKPGEDPRAGRWRG
CEEEECHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KSKTECGIHIGDGK
CCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]