Click here to switch to the map view.

The map label for this gene is fae [H]

Identifier: 154245312

GI number: 154245312

Start: 1567943

End: 1568518

Strand: Reverse

Name: fae [H]

Synonym: Xaut_1365

Alternate gene names: 154245312

Gene position: 1568518-1567943 (Counterclockwise)

Preceding gene: 154245313

Following gene: 154245310

Centisome position: 29.54

GC content: 65.8

Gene sequence:

>576_bases
ATGAAAAGGCAGATACCCCGGCCAGGCCGGCCCCTTTTCAGCACGCCGCGTATTTTTGGAGGTTTCATGCCGAAGATCGA
TCGCCTGATGGTGGGCGAGGCCCTGGTGGGCGAGGGCAACGAGGTGGCCCATATCGACCTCATCATGGGTCCGCGCGGCT
CCTCCGCCGAAACCGCGTTCGTATCCGCTTTGACCAACAACAAGGATGGCTTCACCACCCTGCTGGCCGTGGTGGAGCCC
AACCTTCTGGCCAAGCCCGCCACCGTGCTGTTCAACAAGGTGACCATCAAGGACGCCCGCCAGGCGGTGCAGATGTTCGG
CCCGGCGCAATACGCGGTGGCCAAGGCGGTCACCGACTGCGTGGCCGAGGGGATCATTCCGGTGGAGGAGGCCGACGATG
TCTTCATCTGCGTCGGCGTCTTCATCCACTGGGATGCGAGCGACAATGCGAAGATCCAGGCCTTCAACCACGAGGCCACC
CGCCTTGCCATCCTGCGGGCGGTGAGCGGCACGCCCCGGCCGGCGGACGTGCTGGCGCAGAGCGCGAGCGCGCGGCACCC
CTTCGCCGCCGACTGA

Upstream 100 bases:

>100_bases
GCCGTTCGAGGTGCTGTAGGGCGGTTCCGGCGCCCGCCAGGCCACAATCCAGGCACGGAACGGGCGACCCAAGTTGGCCT
GGGCGCGGTCAGCTTATTGC

Downstream 100 bases:

>100_bases
CGGACGGGCGGCTCGACGCCTAAAGCACAGCTTGCGACAGCCCCAAACGAAAAATGGCGCCCGGCCCCATGGCCAGGCGC
CATCCGGAACCGCGATCAGC

Product: formaldehyde-activating protein

Products: NA

Alternate protein names: Fae [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKRQIPRPGRPLFSTPRIFGGFMPKIDRLMVGEALVGEGNEVAHIDLIMGPRGSSAETAFVSALTNNKDGFTTLLAVVEP
NLLAKPATVLFNKVTIKDARQAVQMFGPAQYAVAKAVTDCVAEGIIPVEEADDVFICVGVFIHWDASDNAKIQAFNHEAT
RLAILRAVSGTPRPADVLAQSASARHPFAAD

Sequences:

>Translated_191_residues
MKRQIPRPGRPLFSTPRIFGGFMPKIDRLMVGEALVGEGNEVAHIDLIMGPRGSSAETAFVSALTNNKDGFTTLLAVVEP
NLLAKPATVLFNKVTIKDARQAVQMFGPAQYAVAKAVTDCVAEGIIPVEEADDVFICVGVFIHWDASDNAKIQAFNHEAT
RLAILRAVSGTPRPADVLAQSASARHPFAAD
>Mature_191_residues
MKRQIPRPGRPLFSTPRIFGGFMPKIDRLMVGEALVGEGNEVAHIDLIMGPRGSSAETAFVSALTNNKDGFTTLLAVVEP
NLLAKPATVLFNKVTIKDARQAVQMFGPAQYAVAKAVTDCVAEGIIPVEEADDVFICVGVFIHWDASDNAKIQAFNHEAT
RLAILRAVSGTPRPADVLAQSASARHPFAAD

Specific function: Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium [H]

COG id: COG1795

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formaldehyde-activating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014826
- InterPro:   IPR020568 [H]

Pfam domain/function: PF08714 Fae [H]

EC number: NA

Molecular weight: Translated: 20452; Mature: 20452

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQIPRPGRPLFSTPRIFGGFMPKIDRLMVGEALVGEGNEVAHIDLIMGPRGSSAETAF
CCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHH
VSALTNNKDGFTTLLAVVEPNLLAKPATVLFNKVTIKDARQAVQMFGPAQYAVAKAVTDC
HHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VAEGIIPVEEADDVFICVGVFIHWDASDNAKIQAFNHEATRLAILRAVSGTPRPADVLAQ
HHHCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
SASARHPFAAD
CCCCCCCCCCC
>Mature Secondary Structure
MKRQIPRPGRPLFSTPRIFGGFMPKIDRLMVGEALVGEGNEVAHIDLIMGPRGSSAETAF
CCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHH
VSALTNNKDGFTTLLAVVEPNLLAKPATVLFNKVTIKDARQAVQMFGPAQYAVAKAVTDC
HHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VAEGIIPVEEADDVFICVGVFIHWDASDNAKIQAFNHEATRLAILRAVSGTPRPADVLAQ
HHHCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
SASARHPFAAD
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9651254; 11073907 [H]