BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is livF [H]

Identifier: 154245303

GI number: 154245303

Start: 1557730

End: 1558407

Strand: Direct

Name: livF [H]

Synonym: Xaut_1356

Alternate gene names: 154245303

Gene position: 1557730-1558407 (Clockwise)

Preceding gene: 154245302

Following gene: 154245304

Centisome position: 29.34

GC content: 68.88

Gene sequence:

>678_bases
ATGCTCATCCTCGATCATGTCACCGTCTCGTTCGGCACGGTCCCGGTGCTGCGCGGCGTGTCGTTCCAGCTCAGGGAAGG
GGAGGCGGTGGCCTTCGTTGGCCGCAACGGCGCCGGCAAGACCACGACGCTGCGCTCCATCATGGGCTTCACCCGGAATG
GCGGGCGCATAGAGTTCGACGGGCACGACCTAGCCGGCGTTGCCGCGCATCTTCGGCCCGGCCTCGGCATCGGCTATGCG
CCGGAGGACCGCCGCCTGTTCTCCCGCTTCACGGTGGAGGAGAACATCCTGCTTCCGGCGCAGGTGGCCAAGCTTTCCAG
CGAGGAGACAAAGCGCCGGCTCGATCGCGTCTACCATGTGCTGCCCGAGCTGAAGGAGATGGCCAGGCGCCCCGCCGGCT
CGGTCTCCGGCGGGCAGGGCAAGATGGTGGCGCTCGGCCGCGCGCTGATGCTCGCCACCCGCCTGGTGCTGCTGGACGAG
CCCTTCCAGGGCCTCGCCCCGGTGCTCGCCAACCGCTACGCCGAGGCCCTGCGGAGCCTGCGCGACACCGATCCCAGCCT
CGCCCTCATCATTACTGAATCGAACCCGCACCTGCTGCGCGGCTTCGCCGAACGCACCATCACCATCGAGCGTGGCGAGA
TCGCGGGCGACGTGCCCAACGAAGGACTGGCCGCATGA

Upstream 100 bases:

>100_bases
GGGTGGCGGTGTGGAGCGCCGGCAAGATCCAGAAGCTCGGCGCCCCGGCCGAGGTGCTGGAGGACCCTGAAGTCATCCGC
ACCGTGATCGGAGTTTGATC

Downstream 100 bases:

>100_bases
ATGAGCTGAACCCCGTGATGCTCGCCAAGGGCGTCTTCATCAACAACGCCTGGCGCCCGGCCGCCTCCGGGCGCGTCATC
GATGTGTACGCTCCGGCCGA

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLILDHVTVSFGTVPVLRGVSFQLREGEAVAFVGRNGAGKTTTLRSIMGFTRNGGRIEFDGHDLAGVAAHLRPGLGIGYA
PEDRRLFSRFTVEENILLPAQVAKLSSEETKRRLDRVYHVLPELKEMARRPAGSVSGGQGKMVALGRALMLATRLVLLDE
PFQGLAPVLANRYAEALRSLRDTDPSLALIITESNPHLLRGFAERTITIERGEIAGDVPNEGLAA

Sequences:

>Translated_225_residues
MLILDHVTVSFGTVPVLRGVSFQLREGEAVAFVGRNGAGKTTTLRSIMGFTRNGGRIEFDGHDLAGVAAHLRPGLGIGYA
PEDRRLFSRFTVEENILLPAQVAKLSSEETKRRLDRVYHVLPELKEMARRPAGSVSGGQGKMVALGRALMLATRLVLLDE
PFQGLAPVLANRYAEALRSLRDTDPSLALIITESNPHLLRGFAERTITIERGEIAGDVPNEGLAA
>Mature_225_residues
MLILDHVTVSFGTVPVLRGVSFQLREGEAVAFVGRNGAGKTTTLRSIMGFTRNGGRIEFDGHDLAGVAAHLRPGLGIGYA
PEDRRLFSRFTVEENILLPAQVAKLSSEETKRRLDRVYHVLPELKEMARRPAGSVSGGQGKMVALGRALMLATRLVLLDE
PFQGLAPVLANRYAEALRSLRDTDPSLALIITESNPHLLRGFAERTITIERGEIAGDVPNEGLAA

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI47078218, Length=152, Percent_Identity=32.8947368421053, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI45446740, Length=152, Percent_Identity=32.8947368421053, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI27477115, Length=166, Percent_Identity=31.3253012048193, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI153792144, Length=152, Percent_Identity=30.2631578947368, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI150417984, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI116734710, Length=150, Percent_Identity=30, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI21536376, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436953, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI6005701, Length=169, Percent_Identity=28.4023668639053, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI27262624, Length=155, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=155, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27881501, Length=171, Percent_Identity=30.4093567251462, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795238, Length=171, Percent_Identity=30.4093567251462, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI105990541, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31657092, Length=207, Percent_Identity=26.5700483091787, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082268, Length=217, Percent_Identity=37.3271889400922, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789593, Length=213, Percent_Identity=34.7417840375587, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=29.1304347826087, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87081791, Length=173, Percent_Identity=34.6820809248555, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788761, Length=223, Percent_Identity=29.5964125560538, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1787792, Length=219, Percent_Identity=31.9634703196347, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788506, Length=210, Percent_Identity=27.6190476190476, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788450, Length=215, Percent_Identity=26.9767441860465, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787105, Length=213, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789873, Length=225, Percent_Identity=27.1111111111111, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790467, Length=163, Percent_Identity=32.5153374233129, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=225, Percent_Identity=28, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789864, Length=228, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786253, Length=225, Percent_Identity=30.6666666666667, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790544, Length=225, Percent_Identity=27.1111111111111, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=25.9090909090909, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=212, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786563, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=209, Percent_Identity=28.2296650717703, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790190, Length=220, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789991, Length=224, Percent_Identity=25.4464285714286, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786975, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788897, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787500, Length=207, Percent_Identity=25.6038647342995, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081834, Length=182, Percent_Identity=30.2197802197802, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786872, Length=229, Percent_Identity=27.9475982532751, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI48995001, Length=187, Percent_Identity=27.807486631016, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788165, Length=168, Percent_Identity=31.547619047619, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=30.8056872037915, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=213, Percent_Identity=26.2910798122066, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786319, Length=219, Percent_Identity=28.310502283105, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786398, Length=188, Percent_Identity=27.1276595744681, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=219, Percent_Identity=25.1141552511416, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=207, Percent_Identity=28.0193236714976, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=147, Percent_Identity=31.2925170068027, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=215, Percent_Identity=23.2558139534884, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988343, Length=223, Percent_Identity=26.9058295964126, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=177, Percent_Identity=29.9435028248588, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=190, Percent_Identity=25.2631578947368, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563255, Length=222, Percent_Identity=26.1261261261261, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24643674, Length=167, Percent_Identity=29.940119760479, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512771, Length=174, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582014, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24582012, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=26.2910798122066, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85725262, Length=180, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45552337, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552347, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552339, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552335, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552363, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552345, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552351, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583969, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920532, Length=160, Percent_Identity=34.375, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580930, Length=160, Percent_Identity=34.375, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552361, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552355, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552353, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552343, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552341, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552349, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581191, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581189, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581193, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581195, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552359, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550972, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45552357, Length=154, Percent_Identity=37.012987012987, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650853, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650855, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585091, Length=204, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 24392; Mature: 24392

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILDHVTVSFGTVPVLRGVSFQLREGEAVAFVGRNGAGKTTTLRSIMGFTRNGGRIEFD
CEEEEEEEECCCCHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEC
GHDLAGVAAHLRPGLGIGYAPEDRRLFSRFTVEENILLPAQVAKLSSEETKRRLDRVYHV
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH
LPELKEMARRPAGSVSGGQGKMVALGRALMLATRLVLLDEPFQGLAPVLANRYAEALRSL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RDTDPSLALIITESNPHLLRGFAERTITIERGEIAGDVPNEGLAA
HCCCCCEEEEEECCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLILDHVTVSFGTVPVLRGVSFQLREGEAVAFVGRNGAGKTTTLRSIMGFTRNGGRIEFD
CEEEEEEEECCCCHHHHCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEC
GHDLAGVAAHLRPGLGIGYAPEDRRLFSRFTVEENILLPAQVAKLSSEETKRRLDRVYHV
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH
LPELKEMARRPAGSVSGGQGKMVALGRALMLATRLVLLDEPFQGLAPVLANRYAEALRSL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RDTDPSLALIITESNPHLLRGFAERTITIERGEIAGDVPNEGLAA
HCCCCCEEEEEECCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]