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The map label for this gene is mmgC [H]

Identifier: 154245293

GI number: 154245293

Start: 1546937

End: 1548100

Strand: Reverse

Name: mmgC [H]

Synonym: Xaut_1346

Alternate gene names: 154245293

Gene position: 1548100-1546937 (Counterclockwise)

Preceding gene: 154245294

Following gene: 154245292

Centisome position: 29.16

GC content: 63.23

Gene sequence:

>1164_bases
ATGCAGACCGTTGGCAGCGACCAGTTCCAGGATATCCGCGACGCGGTGCGCGCGCTGTGCGCGGACTTTCCCGCCGAGTA
CCATCGCAAGGTGGACGAGGCCCGCGCCTATCCGGAAGACTTCGTCGATGCCCTCACCAAGGCCGGCTGGATGGCCGCGC
TGATCCCCGAAGAGTACGGCGGCTCCGGCCTCGGCCTCACCGAGGCCTCCGTGATCATGGAGGAGATCAACCGCGCGGGC
GGCAATTCCGGCGCCTGCCACGGCCAGATGTACAACATGAACACGCTGGTGCGGCACGGTTCCGAGGAGCAGCGCAAGCG
CTACCTGCCGAAGATCGCGGCCGGCGAATTGCGGTTGCAGTCCATGGGCGTCACCGAGCCCACCACCGGCACCGACACCA
CGCGTATCAAGACCACGGCGGTGAAAAAGGGCGACCGCTACGTCATCAACGGCCAGAAGGTCTGGATCTCCCGTGTCCAG
CATTCCGACCTGATGATCCTGCTCGCCCGCACCACGCCCCTCGACCAGGTGAAAAAGAAGTCGGAAGGCCTCTCCATCTT
CATCGTGGACATCAAGGAGGCCATGTCGAAGGGGATGACGGTGCGGCCCATCCTCAACATGGTGAACCACGAGACCAACG
AGCTGTTCTTCGACAACCTGGAGATTCCGGAAGAGAATTTGATCGGCGAGGAGGGCCAGGGGTTCAAATATATCCTCACC
GGCCTGAATGCCGAGCGCACGCTGATCGCGGCCGAATGCATCGGCGACGGCTACTGGTTCATCGACAAGGTTACCGCCTA
CGCCCGCGAACGGGTGGTGTTCGGCCGGCCCATCGGCCAGAACCAGGGGGTGCAATTTCCCATCGCGGAAAGCTTCATCG
AGGTGGAGGCCGCCAACCTCATGCGCTTCGAGGCCTGCCGGCTCTATGATGCGCACCAGCCCTGCGGGACCCAGGCCAAC
ATGGCGAAATACCTCGCCGCCAAGGCCTCGTGGGAAGCCGCCAACGCCTGCCTCCAGTTCCACGGCGGCTTCGGCTTCGC
CTGCGAATACGACATCGAGCGCAAATTCCGCGAGACGCGCCTCTATCAGGTTGCGCCGATCTCCACCAATCTCATCCTGA
GCTATGTGGCCGAGCACGTGCTCGGACTGCCCAGGTCCTTCTAA

Upstream 100 bases:

>100_bases
CCGGCGCCCTCGCCGATGCCATCCTGAACCTGTCCAGCAGCGACGCGGTGAAGCTGAACGCCACCGCGTCCGCCAGCCGA
TAATGAGGGTTTCCGAAACC

Downstream 100 bases:

>100_bases
TATGGGTCGTTCTGACATGACCGGGACATCCGAACTGGACATCGAGCACCTGCGGACCTGGATCGGCCGCGAGGATATCG
GCACCGAGGCGGTGGACCCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MQTVGSDQFQDIRDAVRALCADFPAEYHRKVDEARAYPEDFVDALTKAGWMAALIPEEYGGSGLGLTEASVIMEEINRAG
GNSGACHGQMYNMNTLVRHGSEEQRKRYLPKIAAGELRLQSMGVTEPTTGTDTTRIKTTAVKKGDRYVINGQKVWISRVQ
HSDLMILLARTTPLDQVKKKSEGLSIFIVDIKEAMSKGMTVRPILNMVNHETNELFFDNLEIPEENLIGEEGQGFKYILT
GLNAERTLIAAECIGDGYWFIDKVTAYARERVVFGRPIGQNQGVQFPIAESFIEVEAANLMRFEACRLYDAHQPCGTQAN
MAKYLAAKASWEAANACLQFHGGFGFACEYDIERKFRETRLYQVAPISTNLILSYVAEHVLGLPRSF

Sequences:

>Translated_387_residues
MQTVGSDQFQDIRDAVRALCADFPAEYHRKVDEARAYPEDFVDALTKAGWMAALIPEEYGGSGLGLTEASVIMEEINRAG
GNSGACHGQMYNMNTLVRHGSEEQRKRYLPKIAAGELRLQSMGVTEPTTGTDTTRIKTTAVKKGDRYVINGQKVWISRVQ
HSDLMILLARTTPLDQVKKKSEGLSIFIVDIKEAMSKGMTVRPILNMVNHETNELFFDNLEIPEENLIGEEGQGFKYILT
GLNAERTLIAAECIGDGYWFIDKVTAYARERVVFGRPIGQNQGVQFPIAESFIEVEAANLMRFEACRLYDAHQPCGTQAN
MAKYLAAKASWEAANACLQFHGGFGFACEYDIERKFRETRLYQVAPISTNLILSYVAEHVLGLPRSF
>Mature_387_residues
MQTVGSDQFQDIRDAVRALCADFPAEYHRKVDEARAYPEDFVDALTKAGWMAALIPEEYGGSGLGLTEASVIMEEINRAG
GNSGACHGQMYNMNTLVRHGSEEQRKRYLPKIAAGELRLQSMGVTEPTTGTDTTRIKTTAVKKGDRYVINGQKVWISRVQ
HSDLMILLARTTPLDQVKKKSEGLSIFIVDIKEAMSKGMTVRPILNMVNHETNELFFDNLEIPEENLIGEEGQGFKYILT
GLNAERTLIAAECIGDGYWFIDKVTAYARERVVFGRPIGQNQGVQFPIAESFIEVEAANLMRFEACRLYDAHQPCGTQAN
MAKYLAAKASWEAANACLQFHGGFGFACEYDIERKFRETRLYQVAPISTNLILSYVAEHVLGLPRSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=380, Percent_Identity=30.5263157894737, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=28.6472148541114, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=30.4812834224599, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=32.4483775811209, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4557231, Length=363, Percent_Identity=32.7823691460055, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI187960098, Length=363, Percent_Identity=32.7823691460055, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=29.8153034300792, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI7656849, Length=354, Percent_Identity=28.8135593220339, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=27.9373368146214, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI76496475, Length=357, Percent_Identity=27.7310924369748, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4557235, Length=357, Percent_Identity=27.7310924369748, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7669494, Length=351, Percent_Identity=25.3561253561254, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4503943, Length=351, Percent_Identity=25.3561253561254, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI211971008, Length=322, Percent_Identity=25.1552795031056, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI48976061, Length=322, Percent_Identity=25.1552795031056, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38505218, Length=330, Percent_Identity=26.3636363636364, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI87081958, Length=367, Percent_Identity=29.1553133514986, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786223, Length=355, Percent_Identity=27.887323943662, Blast_Score=147, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=368, Percent_Identity=35.054347826087, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=31.0344827586207, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17538396, Length=365, Percent_Identity=31.5068493150685, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=31.0704960835509, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=28.9544235924933, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=29.1338582677165, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=32.3432343234323, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=29.1316526610644, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=29.5514511873351, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=334, Percent_Identity=29.6407185628743, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=332, Percent_Identity=30.1204819277108, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=269, Percent_Identity=31.9702602230483, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=249, Percent_Identity=30.9236947791165, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=303, Percent_Identity=27.3927392739274, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=230, Percent_Identity=28.695652173913, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=310, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356377, Length=341, Percent_Identity=33.1378299120235, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=32.2916666666667, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24660351, Length=340, Percent_Identity=33.8235294117647, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21355753, Length=331, Percent_Identity=30.8157099697885, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281363737, Length=397, Percent_Identity=28.2115869017632, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=27.5324675324675, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI19920834, Length=357, Percent_Identity=26.3305322128852, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43202; Mature: 43202

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVGSDQFQDIRDAVRALCADFPAEYHRKVDEARAYPEDFVDALTKAGWMAALIPEEYG
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCHHCC
GSGLGLTEASVIMEEINRAGGNSGACHGQMYNMNTLVRHGSEEQRKRYLPKIAAGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCCHHHHHHHCCCHHHCCEEEE
SMGVTEPTTGTDTTRIKTTAVKKGDRYVINGQKVWISRVQHSDLMILLARTTPLDQVKKK
CCCCCCCCCCCCCCEEEEEEECCCCEEEECCCEEEEEHHCCCCEEEEEECCCCHHHHHHH
SEGLSIFIVDIKEAMSKGMTVRPILNMVNHETNELFFDNLEIPEENLIGEEGQGFKYILT
CCCCEEEEEEHHHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCHHHCCCCCCCCCEEEEE
GLNAERTLIAAECIGDGYWFIDKVTAYARERVVFGRPIGQNQGVQFPIAESFIEVEAANL
CCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHH
MRFEACRLYDAHQPCGTQANMAKYLAAKASWEAANACLQFHGGFGFACEYDIERKFRETR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
LYQVAPISTNLILSYVAEHVLGLPRSF
CEEEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQTVGSDQFQDIRDAVRALCADFPAEYHRKVDEARAYPEDFVDALTKAGWMAALIPEEYG
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCHHCC
GSGLGLTEASVIMEEINRAGGNSGACHGQMYNMNTLVRHGSEEQRKRYLPKIAAGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCCHHHHHHHCCCHHHCCEEEE
SMGVTEPTTGTDTTRIKTTAVKKGDRYVINGQKVWISRVQHSDLMILLARTTPLDQVKKK
CCCCCCCCCCCCCCEEEEEEECCCCEEEECCCEEEEEHHCCCCEEEEEECCCCHHHHHHH
SEGLSIFIVDIKEAMSKGMTVRPILNMVNHETNELFFDNLEIPEENLIGEEGQGFKYILT
CCCCEEEEEEHHHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCHHHCCCCCCCCCEEEEE
GLNAERTLIAAECIGDGYWFIDKVTAYARERVVFGRPIGQNQGVQFPIAESFIEVEAANL
CCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHH
MRFEACRLYDAHQPCGTQANMAKYLAAKASWEAANACLQFHGGFGFACEYDIERKFRETR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
LYQVAPISTNLILSYVAEHVLGLPRSF
CEEEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]