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The map label for this gene is acxB [H]

Identifier: 154245289

GI number: 154245289

Start: 1541769

End: 1544087

Strand: Direct

Name: acxB [H]

Synonym: Xaut_1342

Alternate gene names: 154245289

Gene position: 1541769-1544087 (Clockwise)

Preceding gene: 154245288

Following gene: 154245290

Centisome position: 29.04

GC content: 64.29

Gene sequence:

>2319_bases
ATGGCGCTGCGATCACCTGAGATAATCCGGGAGGATAAACCCATGAACGACATGAGCATCGCCGGCCGCGGCAAGCTGCC
CAGCGCCGAAGAGGCTGCCCTGGTCCGGAAGTTCCTGAACGACACCACCTTGTTCCTCGGCCCCGACCCCGAGATCATGC
AGAACCACGACCTCATGCCGCGTACGGCGGACGAGGAAGAGGCCATCACCAAGGTGGCCGACAGCCACATCATCGCCAAG
ATCCGCGATCGCATCCAGGCCGGCTGCGACGAAGGCTACGAGATGGTGGAGCAGATGGGTGCCGCCCCCGGCGCCAAGTG
GGGCGACGTGATTACCGGCGTGTATTCGGCCTCCGGCGATCTGGCCATCGCCTCCGCCGGCGGCGTGCTGATCTTCTCGG
CGCTGGTGCACCACCCCATCAAGTTCATCATCAAGAACTGGATGAATGATCCGACCGTCGGGGTGCGGGAAGGCGACGGC
TTCATCCACAACGACAGCCGCTACGGCAACGTCCACAACACCGACCAGTCCATGATCGTGCCCATCTTCCACAAGGGCAA
GCTCGTGTGCTGGGTGGCCTCCACCGTGCATGAGGGCGAGAACGGTGCCATCGAGCCGGGCGGCATGCCCTCCATGGCGG
AGAGCCCGTCCGACGAGGGGTTGAAGATGTCGCCCTTCCGCGTGGTCGAGAACTACCAGATCAAGCGCGATATCCTCACC
TTCCTGCAGAATTCGGTGCGCGAGCCCAAGCTGCAATATGAAGACATGAAGGTGAAGCTGTTCGCCTGCCTGCGCATCAA
GCAGCGCATCGAGGAGACGCTGAACACCGACGGCCCGGAGGCCCTCGTCTCCACCCTGCGCCTGACCATGGAGAATGTGC
GCGCCGAGGTGAAGCGCCGCATTTCCGAGTGGCCGGACATGACGGTGCGCACCTACATCATCCAGGATTCGACACTGCGC
GAGAATTGCGTGGTGAAGATCAACTGCAAGCTGACCAAGACCGGCGACCGGCTGATCTTCGATTTCCGCGGCTCCGCGCC
GGAATTCACCAACCGCGCCACCAATACCATCGTCGCCGGCCTCAAGGGCATGCTGGCGCAGGTGTTCCTGTGTTATGTGT
GGCCGGACCTGCCGCGCGGGCAGGCGGCCTTCGCCCCCATCGAGGTCATCACCGACCCCCATTCCATCGTCAACTGCTCC
TATGATGCGCCCAATTCGCAGAGCCTGATGTCCATCTTCACGGGCTTCACGGCGGGCCAGCACGCGGTGGCGAAGTTCCT
CTATTCCTGCCCGGAGAAGTTCACCAAGGTCCACGCCCCGACCTTCAACATGATCAACACCTTCATCTGGGGCGGCGTGT
CCCAGCACGGCGAGACCCTGGGCAACCTCTGCGCCGACCTCAACGGCATGGGCGCGGGCGCCACCGTGGACCGGGACGGC
GAGCATGCGCTGGCCCCCATCTTCGCCACCATGGCCGACATCGGCGAGCAGGAGCTGAACGAGGAAGAGGTGCCGTTCCT
CCAGCTCGTGTCCAAGAAGATGACACGCGATGCCATCGCGCCGGGCAAGTATCGCGGCGGCCAGGGCTACACCATGATGG
TGGCCACCAAGGACAGCGAGCAGTGGGGCTTCATGACCACCTGCCAGGGCGCCAAGATCCCGCCGCTCCAGGGGCTGTTC
GGCGGCTATGCCTGCGGCTGCTATCCTCTGTCCAAGGTGAAGGGCGTGGATGTCTACGACGTGCTGCAGAACACGCCGGA
GAAGTTCAAGCACTCCATCGAGGAGATCATGAACGAGCAGCCCTTCGAGGGCGCCAGCTACACCACCCACCACATGGGCA
TGGGCTTTGAAATCTCGAAGCGCGGCGAGCTGTTCATGATCTCGCAGGGGGCAGGCGCCGGCTACGGCGATCTGCTGGAG
CGCGACCCAAGGGGCGTCATCAAGGACATCGAGGAGGGGCTGATCTCCCCGGAGGTCGCCGCCCGCCTCTACAAGGTGGC
GTTCGACCCCGAGACCCTCGCCATCGACGAGGCGGCCACCGAAGTGGCGCGCGCCGCCGAGCGCAAGGCCCGCATCGCCC
GCTCCAGGCCCTATTCGGACTTTGTGAAGGACTGGAGCAAGCCCACGCCGCCGACCCACCTGCAGTATTTCGGTGCGTGG
GGCGATGATGTCCAGACCCTCTACATGGGCAGCCCGCACAAGACCCGCGACGCTGAAACCCCGCGCCCCAACTACATGCC
GCATCCGAAGGATGTGCGCATCGCCGAGCTTGAGGCCCGTCTCGCCGCCGTCGGCGCCATGGGGGGCGAGAAGCAATGA

Upstream 100 bases:

>100_bases
CGGCAAAGCAGGGGGCCTCCTGGTTCCTGCGCGCCAAGATCCCCGCCACCACGCACTGACGCCGTTTCTCTCCCCGCCCC
GCGCGGGGAGAGCGCGCCCC

Downstream 100 bases:

>100_bases
GCCCACGGCTCGTGGATGCCCTGCCGCGTCCGTCCGGCGCGCCCGGGCTCAGGGTCTGGCTGAAGTCGTCGGGCTATGCC
CGGCGCCTTCTGCTCGGCGA

Product: hydantoinase B/oxoprolinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MALRSPEIIREDKPMNDMSIAGRGKLPSAEEAALVRKFLNDTTLFLGPDPEIMQNHDLMPRTADEEEAITKVADSHIIAK
IRDRIQAGCDEGYEMVEQMGAAPGAKWGDVITGVYSASGDLAIASAGGVLIFSALVHHPIKFIIKNWMNDPTVGVREGDG
FIHNDSRYGNVHNTDQSMIVPIFHKGKLVCWVASTVHEGENGAIEPGGMPSMAESPSDEGLKMSPFRVVENYQIKRDILT
FLQNSVREPKLQYEDMKVKLFACLRIKQRIEETLNTDGPEALVSTLRLTMENVRAEVKRRISEWPDMTVRTYIIQDSTLR
ENCVVKINCKLTKTGDRLIFDFRGSAPEFTNRATNTIVAGLKGMLAQVFLCYVWPDLPRGQAAFAPIEVITDPHSIVNCS
YDAPNSQSLMSIFTGFTAGQHAVAKFLYSCPEKFTKVHAPTFNMINTFIWGGVSQHGETLGNLCADLNGMGAGATVDRDG
EHALAPIFATMADIGEQELNEEEVPFLQLVSKKMTRDAIAPGKYRGGQGYTMMVATKDSEQWGFMTTCQGAKIPPLQGLF
GGYACGCYPLSKVKGVDVYDVLQNTPEKFKHSIEEIMNEQPFEGASYTTHHMGMGFEISKRGELFMISQGAGAGYGDLLE
RDPRGVIKDIEEGLISPEVAARLYKVAFDPETLAIDEAATEVARAAERKARIARSRPYSDFVKDWSKPTPPTHLQYFGAW
GDDVQTLYMGSPHKTRDAETPRPNYMPHPKDVRIAELEARLAAVGAMGGEKQ

Sequences:

>Translated_772_residues
MALRSPEIIREDKPMNDMSIAGRGKLPSAEEAALVRKFLNDTTLFLGPDPEIMQNHDLMPRTADEEEAITKVADSHIIAK
IRDRIQAGCDEGYEMVEQMGAAPGAKWGDVITGVYSASGDLAIASAGGVLIFSALVHHPIKFIIKNWMNDPTVGVREGDG
FIHNDSRYGNVHNTDQSMIVPIFHKGKLVCWVASTVHEGENGAIEPGGMPSMAESPSDEGLKMSPFRVVENYQIKRDILT
FLQNSVREPKLQYEDMKVKLFACLRIKQRIEETLNTDGPEALVSTLRLTMENVRAEVKRRISEWPDMTVRTYIIQDSTLR
ENCVVKINCKLTKTGDRLIFDFRGSAPEFTNRATNTIVAGLKGMLAQVFLCYVWPDLPRGQAAFAPIEVITDPHSIVNCS
YDAPNSQSLMSIFTGFTAGQHAVAKFLYSCPEKFTKVHAPTFNMINTFIWGGVSQHGETLGNLCADLNGMGAGATVDRDG
EHALAPIFATMADIGEQELNEEEVPFLQLVSKKMTRDAIAPGKYRGGQGYTMMVATKDSEQWGFMTTCQGAKIPPLQGLF
GGYACGCYPLSKVKGVDVYDVLQNTPEKFKHSIEEIMNEQPFEGASYTTHHMGMGFEISKRGELFMISQGAGAGYGDLLE
RDPRGVIKDIEEGLISPEVAARLYKVAFDPETLAIDEAATEVARAAERKARIARSRPYSDFVKDWSKPTPPTHLQYFGAW
GDDVQTLYMGSPHKTRDAETPRPNYMPHPKDVRIAELEARLAAVGAMGGEKQ
>Mature_771_residues
ALRSPEIIREDKPMNDMSIAGRGKLPSAEEAALVRKFLNDTTLFLGPDPEIMQNHDLMPRTADEEEAITKVADSHIIAKI
RDRIQAGCDEGYEMVEQMGAAPGAKWGDVITGVYSASGDLAIASAGGVLIFSALVHHPIKFIIKNWMNDPTVGVREGDGF
IHNDSRYGNVHNTDQSMIVPIFHKGKLVCWVASTVHEGENGAIEPGGMPSMAESPSDEGLKMSPFRVVENYQIKRDILTF
LQNSVREPKLQYEDMKVKLFACLRIKQRIEETLNTDGPEALVSTLRLTMENVRAEVKRRISEWPDMTVRTYIIQDSTLRE
NCVVKINCKLTKTGDRLIFDFRGSAPEFTNRATNTIVAGLKGMLAQVFLCYVWPDLPRGQAAFAPIEVITDPHSIVNCSY
DAPNSQSLMSIFTGFTAGQHAVAKFLYSCPEKFTKVHAPTFNMINTFIWGGVSQHGETLGNLCADLNGMGAGATVDRDGE
HALAPIFATMADIGEQELNEEEVPFLQLVSKKMTRDAIAPGKYRGGQGYTMMVATKDSEQWGFMTTCQGAKIPPLQGLFG
GYACGCYPLSKVKGVDVYDVLQNTPEKFKHSIEEIMNEQPFEGASYTTHHMGMGFEISKRGELFMISQGAGAGYGDLLER
DPRGVIKDIEEGLISPEVAARLYKVAFDPETLAIDEAATEVARAAERKARIARSRPYSDFVKDWSKPTPPTHLQYFGAWG
DDVQTLYMGSPHKTRDAETPRPNYMPHPKDVRIAELEARLAAVGAMGGEKQ

Specific function: Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide [H]

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133901902, Length=311, Percent_Identity=22.8295819935691, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI133901900, Length=357, Percent_Identity=21.8487394957983, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: =6.4.1.6 [H]

Molecular weight: Translated: 85236; Mature: 85105

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRSPEIIREDKPMNDMSIAGRGKLPSAEEAALVRKFLNDTTLFLGPDPEIMQNHDLMP
CCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHCCCCCCC
RTADEEEAITKVADSHIIAKIRDRIQAGCDEGYEMVEQMGAAPGAKWGDVITGVYSASGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
LAIASAGGVLIFSALVHHPIKFIIKNWMNDPTVGVREGDGFIHNDSRYGNVHNTDQSMIV
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEE
PIFHKGKLVCWVASTVHEGENGAIEPGGMPSMAESPSDEGLKMSPFRVVENYQIKRDILT
EEEECCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHH
FLQNSVREPKLQYEDMKVKLFACLRIKQRIEETLNTDGPEALVSTLRLTMENVRAEVKRR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ISEWPDMTVRTYIIQDSTLRENCVVKINCKLTKTGDRLIFDFRGSAPEFTNRATNTIVAG
HHHCCCCEEEEEEEECCCCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
LKGMLAQVFLCYVWPDLPRGQAAFAPIEVITDPHSIVNCSYDAPNSQSLMSIFTGFTAGQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHEEECCCCCCHHHHHHHHHHCCCCH
HAVAKFLYSCPEKFTKVHAPTFNMINTFIWGGVSQHGETLGNLCADLNGMGAGATVDRDG
HHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EHALAPIFATMADIGEQELNEEEVPFLQLVSKKMTRDAIAPGKYRGGQGYTMMVATKDSE
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
QWGFMTTCQGAKIPPLQGLFGGYACGCYPLSKVKGVDVYDVLQNTPEKFKHSIEEIMNEQ
CCCCEEECCCCCCCCHHHHHCCCEECCEEHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCC
PFEGASYTTHHMGMGFEISKRGELFMISQGAGAGYGDLLERDPRGVIKDIEEGLISPEVA
CCCCCCCEEHHCCCCEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHCCCCHHHH
ARLYKVAFDPETLAIDEAATEVARAAERKARIARSRPYSDFVKDWSKPTPPTHLQYFGAW
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCC
GDDVQTLYMGSPHKTRDAETPRPNYMPHPKDVRIAELEARLAAVGAMGGEKQ
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALRSPEIIREDKPMNDMSIAGRGKLPSAEEAALVRKFLNDTTLFLGPDPEIMQNHDLMP
CCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHCCCCCCC
RTADEEEAITKVADSHIIAKIRDRIQAGCDEGYEMVEQMGAAPGAKWGDVITGVYSASGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
LAIASAGGVLIFSALVHHPIKFIIKNWMNDPTVGVREGDGFIHNDSRYGNVHNTDQSMIV
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCCCCCCCEEE
PIFHKGKLVCWVASTVHEGENGAIEPGGMPSMAESPSDEGLKMSPFRVVENYQIKRDILT
EEEECCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHH
FLQNSVREPKLQYEDMKVKLFACLRIKQRIEETLNTDGPEALVSTLRLTMENVRAEVKRR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ISEWPDMTVRTYIIQDSTLRENCVVKINCKLTKTGDRLIFDFRGSAPEFTNRATNTIVAG
HHHCCCCEEEEEEEECCCCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
LKGMLAQVFLCYVWPDLPRGQAAFAPIEVITDPHSIVNCSYDAPNSQSLMSIFTGFTAGQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHEEECCCCCCHHHHHHHHHHCCCCH
HAVAKFLYSCPEKFTKVHAPTFNMINTFIWGGVSQHGETLGNLCADLNGMGAGATVDRDG
HHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EHALAPIFATMADIGEQELNEEEVPFLQLVSKKMTRDAIAPGKYRGGQGYTMMVATKDSE
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
QWGFMTTCQGAKIPPLQGLFGGYACGCYPLSKVKGVDVYDVLQNTPEKFKHSIEEIMNEQ
CCCCEEECCCCCCCCHHHHHCCCEECCEEHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCC
PFEGASYTTHHMGMGFEISKRGELFMISQGAGAGYGDLLERDPRGVIKDIEEGLISPEVA
CCCCCCCEEHHCCCCEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHCCCCHHHH
ARLYKVAFDPETLAIDEAATEVARAAERKARIARSRPYSDFVKDWSKPTPPTHLQYFGAW
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCC
GDDVQTLYMGSPHKTRDAETPRPNYMPHPKDVRIAELEARLAAVGAMGGEKQ
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12003937 [H]