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The map label for this gene is pdxY [H]

Identifier: 154245273

GI number: 154245273

Start: 1520617

End: 1521465

Strand: Direct

Name: pdxY [H]

Synonym: Xaut_1325

Alternate gene names: 154245273

Gene position: 1520617-1521465 (Clockwise)

Preceding gene: 154245266

Following gene: 154245274

Centisome position: 28.64

GC content: 68.67

Gene sequence:

>849_bases
ATGAATCTCCTCTCCATCCAGTCCCATGTCGCCTACGGCCATGTGGGCAATGCCTCCGCCGTATTTCCGCTCCAGCGGCT
CGGGGTGGAGGTGTGGGCCATCAACACCGTGCAGTTCTCCAATCACACCGGCTACGGGGCGTGGCGCGGGCAGGTGTTCG
AGGCGGCGGTCATCGGCGAGCTGGTGGAGGGCATCACCGAGCGCGGGGTGCTGCCGCGCTGCGACGGCGTGCTCTCCGGC
TACATGGGCTCGGCGGACATCGGCGCCGCCATCCTCGACGCGGTGGCGCGGGTGAAGGCGGCCAACCGCAATGCCGCCTA
TTGCTGCGACCCGGTGATCGGCGACGTTGGGCGCGGCATCTTCGTGCGCCCCGGCATCCCCGAACTGATGCGCGATCTCG
CGGTGCCGGCGGCGGACGTGATCACCCCCAACCAGTTCGAGCTGGAGCTGCTCTCGGGCCGCGCCTGCGCCTATATCGAC
GATGCGATCGCGGCTTGCGACGCCCTCCACGCCCGGGGTCCGAAGGTGATTCTCGTCACCAGCCTCAACGTGGCGGAGAC
CCCGCCCGATTGCATCGACCTGATCGCCTCGGGGCCGGACGGGCGCTTCCTGGTGCGCACGCCGCGCCTCGCAGTCTCGC
TCAACGGGGCGGGGGATGCCATCGCCGCCCTGTTCTTCTTCCACGTCCAGCGCACGGGATCGACCGCCGAGGCGGTTTCC
GCCGCCGCATCCTCCATTTACGGGGTGCTGGAGCGGACGGAAAAAGCACAGTCTCGGGAATTGCTGCTGGTGGAGGCCCA
GGACGAGTTCGTGCGGCCCTCCCGGCTCTTTCCCGCCTCGGTGATCTGA

Upstream 100 bases:

>100_bases
GATCAACAGATTCCATTTGAGAAGGGCGCTGCGGCAGGCTAACCGGCGGATTGCGGGCGCCGGCCATCAGGCGGTGGCCC
CGATCGCGGGATCCGAGCCC

Downstream 100 bases:

>100_bases
GGCAAAAATGTGGCGGCCACCCCCGTGGCTGCCGTGACCCGGAAGACGCCGTGCGCGTGCATGCTGCGGTCACAGAGACC
TGTAGAGACCTGTTCGCATG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWAINTVQFSNHTGYGAWRGQVFEAAVIGELVEGITERGVLPRCDGVLSG
YMGSADIGAAILDAVARVKAANRNAAYCCDPVIGDVGRGIFVRPGIPELMRDLAVPAADVITPNQFELELLSGRACAYID
DAIAACDALHARGPKVILVTSLNVAETPPDCIDLIASGPDGRFLVRTPRLAVSLNGAGDAIAALFFFHVQRTGSTAEAVS
AAASSIYGVLERTEKAQSRELLLVEAQDEFVRPSRLFPASVI

Sequences:

>Translated_282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWAINTVQFSNHTGYGAWRGQVFEAAVIGELVEGITERGVLPRCDGVLSG
YMGSADIGAAILDAVARVKAANRNAAYCCDPVIGDVGRGIFVRPGIPELMRDLAVPAADVITPNQFELELLSGRACAYID
DAIAACDALHARGPKVILVTSLNVAETPPDCIDLIASGPDGRFLVRTPRLAVSLNGAGDAIAALFFFHVQRTGSTAEAVS
AAASSIYGVLERTEKAQSRELLLVEAQDEFVRPSRLFPASVI
>Mature_282_residues
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWAINTVQFSNHTGYGAWRGQVFEAAVIGELVEGITERGVLPRCDGVLSG
YMGSADIGAAILDAVARVKAANRNAAYCCDPVIGDVGRGIFVRPGIPELMRDLAVPAADVITPNQFELELLSGRACAYID
DAIAACDALHARGPKVILVTSLNVAETPPDCIDLIASGPDGRFLVRTPRLAVSLNGAGDAIAALFFFHVQRTGSTAEAVS
AAASSIYGVLERTEKAQSRELLLVEAQDEFVRPSRLFPASVI

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=308, Percent_Identity=35.3896103896104, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1787924, Length=282, Percent_Identity=39.7163120567376, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788758, Length=262, Percent_Identity=30.9160305343511, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17507759, Length=285, Percent_Identity=36.4912280701754, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17507757, Length=295, Percent_Identity=35.2542372881356, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6324354, Length=237, Percent_Identity=35.8649789029536, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320806, Length=261, Percent_Identity=34.8659003831418, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45553007, Length=299, Percent_Identity=33.7792642140468, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 29799; Mature: 29799

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWAINTVQFSNHTGYGAWRGQVFEAAVIGE
CCCEECHHHHEECCCCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
LVEGITERGVLPRCDGVLSGYMGSADIGAAILDAVARVKAANRNAAYCCDPVIGDVGRGI
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCE
FVRPGIPELMRDLAVPAADVITPNQFELELLSGRACAYIDDAIAACDALHARGPKVILVT
EECCCHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEEEE
SLNVAETPPDCIDLIASGPDGRFLVRTPRLAVSLNGAGDAIAALFFFHVQRTGSTAEAVS
ECCCCCCCHHHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHH
AAASSIYGVLERTEKAQSRELLLVEAQDEFVRPSRLFPASVI
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLLSIQSHVAYGHVGNASAVFPLQRLGVEVWAINTVQFSNHTGYGAWRGQVFEAAVIGE
CCCEECHHHHEECCCCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
LVEGITERGVLPRCDGVLSGYMGSADIGAAILDAVARVKAANRNAAYCCDPVIGDVGRGI
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCE
FVRPGIPELMRDLAVPAADVITPNQFELELLSGRACAYIDDAIAACDALHARGPKVILVT
EECCCHHHHHHHHCCCHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEEEE
SLNVAETPPDCIDLIASGPDGRFLVRTPRLAVSLNGAGDAIAALFFFHVQRTGSTAEAVS
ECCCCCCCHHHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHH
AAASSIYGVLERTEKAQSRELLLVEAQDEFVRPSRLFPASVI
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA