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The map label for this gene is aidB [H]

Identifier: 154245212

GI number: 154245212

Start: 1453194

End: 1454831

Strand: Reverse

Name: aidB [H]

Synonym: Xaut_1264

Alternate gene names: 154245212

Gene position: 1454831-1453194 (Counterclockwise)

Preceding gene: 154245213

Following gene: 154245211

Centisome position: 27.4

GC content: 70.82

Gene sequence:

>1638_bases
ATGGACTTCACGCACCTCGCGGACGAGGTCTCGAACCAGCCGCCGCCCTACGGCGACATCAATCTCGCCGCCGGAGACCC
CGCCCTCGCCGCCGCGTCCGAGCGGGCCGGCATGAACGGCGGTGCCTTTGCCTTCGGCGGCCAATGGGGCGGCTCGGACC
AGCTTGCCCTCGGCCGCCTGGCCAATGAGAACCCGCCGGAGTTGCACAGTCACGACCCCCAGGGCCGCCGCTGCGACGTG
GTGGAATTCCACCCCGCCTATCACGCCTTGATGGCGCAAAGCATGGATGCGGGGCTCCACTGTTCCAGCTGGGATGGCCC
GGCACGACCGGCCGAGGCGCGGCGCGGCAATGCCCAGCGCGCGACCCGGCTCTATGTGGTGAGCCAGGTGGAGGCGGGCC
ACGTCTGCCCGCTCACCATGACCCACGCCGCCCCCGCAAGCCTTGCCGCGGCACCGGAGCTGCTGCGCGATTTCCTGCCC
CGCATCCGCGCCCGCAACTATGACGGCCGCTTCGTGCCGTTCTGGGAGAAGGCCTCCGTCACCATCGGCATGAGCATGAC
GGAGCGGCAGGGCGGCACCGACGTACGCTCCAACACCACCCAGGCCGTGCCCATCGGCGGTAGCGAATACGAGATCACCG
GCGCCAAGTGGTTCCTCTCGGCCCCCATGAGCGACGCCTTCCTGGTGCTGGCGCAGGCGCCCGGCGGCCTCACCGCCTTC
CTGATGCCCCGCTTCCGGCCAGACGGCAGCGTCAACGGGGTCCGCCTCACCCGGCTCAAGCGCAAGCTCGGCAACCGCTC
CAACGCCTCCTGCGAAGTGGAGTTCGAGCGCGCCTTCGCCTGGCGGGTGGGCGAGGAGGGGCGCGGCATACCCACCATCA
TCGGCATGGTGCAGATGACGCGGCTGGACTGCGCCGTCTCCTCCGCCGGCCTGATGCGCGCGGCGTTGGCGCGGGCGCTG
CACCATGCCCGCCATCGTACCGCGTTCCAGAAGAAGCTTGTGGACCAGCCGGCCATGGCCATGGTGCTGGCCGACCTCGC
GCTCGACCAGGAAGCCTTCGCCGCCCTCGCCTTCCGCCTTGCCCTGAGCTTCGACGAAGCGAACGGCTCCGGCACCGAGG
CCGCCCATGCCCGGGTGCTGACGCCGGTGGCGAAATTCGCCGTGTGCAAGGCGGCGCCAGCCTTCATCGCCGAGACCATG
GAGGTGCTGGGCGGTAACGGCTACGTGGAGGACTGCGCCCTGCCGCGCCTCTATCGCGAGGCGCCGGTCAACGCCATCTG
GGAAGGCTCGGGCAATGTGATGGCGCTGGACCTCGCCCGCGTCGCCTTCCGTGAGCCGGATCTGGTGCAGGCGATTCTCG
CCAACCTCAAGGAGCGCACGCGCGGCCTGCCCGGCGCCGCCAGCACGGCAGAAACCGTATCCCGGTGCCTTCAGTCCGGC
GACCGCGAGGCCCACGCACGGCGCGCCGCCGAGGCCCTGGCCCTGCTGGCTGCGGCAGCGGCTCTCGCCGAATCGGCACC
GACCGCGGTGACGGAAGCCTTTGCAGCCACGCGCCTTGCCACGGCACGGGGCATCTACGGCGCCAACGCCATCGATGCCG
TGCGCGACCTCATGCTCGAACGGACGCTTGCCGCGTGA

Upstream 100 bases:

>100_bases
CAATTTGCCTGTGTCGGACCCGTGGGCATGCACCTGCGGGCCGGCCGGTTCCGGCGCACCGCTCCCGAGACGAGGAGCCG
GGCCCCGGCGAGGAAACGCC

Downstream 100 bases:

>100_bases
GGGGGCTGGGCCTCTCCTGTGGCGCGCTGTTGCCGGGCGCTGCTGCCCCGGGCTGTTGTCGCGCGCTCTTGCCATGTGCT
CTTTCCGCTCGCTCTTGCCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MDFTHLADEVSNQPPPYGDINLAAGDPALAAASERAGMNGGAFAFGGQWGGSDQLALGRLANENPPELHSHDPQGRRCDV
VEFHPAYHALMAQSMDAGLHCSSWDGPARPAEARRGNAQRATRLYVVSQVEAGHVCPLTMTHAAPASLAAAPELLRDFLP
RIRARNYDGRFVPFWEKASVTIGMSMTERQGGTDVRSNTTQAVPIGGSEYEITGAKWFLSAPMSDAFLVLAQAPGGLTAF
LMPRFRPDGSVNGVRLTRLKRKLGNRSNASCEVEFERAFAWRVGEEGRGIPTIIGMVQMTRLDCAVSSAGLMRAALARAL
HHARHRTAFQKKLVDQPAMAMVLADLALDQEAFAALAFRLALSFDEANGSGTEAAHARVLTPVAKFAVCKAAPAFIAETM
EVLGGNGYVEDCALPRLYREAPVNAIWEGSGNVMALDLARVAFREPDLVQAILANLKERTRGLPGAASTAETVSRCLQSG
DREAHARRAAEALALLAAAAALAESAPTAVTEAFAATRLATARGIYGANAIDAVRDLMLERTLAA

Sequences:

>Translated_545_residues
MDFTHLADEVSNQPPPYGDINLAAGDPALAAASERAGMNGGAFAFGGQWGGSDQLALGRLANENPPELHSHDPQGRRCDV
VEFHPAYHALMAQSMDAGLHCSSWDGPARPAEARRGNAQRATRLYVVSQVEAGHVCPLTMTHAAPASLAAAPELLRDFLP
RIRARNYDGRFVPFWEKASVTIGMSMTERQGGTDVRSNTTQAVPIGGSEYEITGAKWFLSAPMSDAFLVLAQAPGGLTAF
LMPRFRPDGSVNGVRLTRLKRKLGNRSNASCEVEFERAFAWRVGEEGRGIPTIIGMVQMTRLDCAVSSAGLMRAALARAL
HHARHRTAFQKKLVDQPAMAMVLADLALDQEAFAALAFRLALSFDEANGSGTEAAHARVLTPVAKFAVCKAAPAFIAETM
EVLGGNGYVEDCALPRLYREAPVNAIWEGSGNVMALDLARVAFREPDLVQAILANLKERTRGLPGAASTAETVSRCLQSG
DREAHARRAAEALALLAAAAALAESAPTAVTEAFAATRLATARGIYGANAIDAVRDLMLERTLAA
>Mature_545_residues
MDFTHLADEVSNQPPPYGDINLAAGDPALAAASERAGMNGGAFAFGGQWGGSDQLALGRLANENPPELHSHDPQGRRCDV
VEFHPAYHALMAQSMDAGLHCSSWDGPARPAEARRGNAQRATRLYVVSQVEAGHVCPLTMTHAAPASLAAAPELLRDFLP
RIRARNYDGRFVPFWEKASVTIGMSMTERQGGTDVRSNTTQAVPIGGSEYEITGAKWFLSAPMSDAFLVLAQAPGGLTAF
LMPRFRPDGSVNGVRLTRLKRKLGNRSNASCEVEFERAFAWRVGEEGRGIPTIIGMVQMTRLDCAVSSAGLMRAALARAL
HHARHRTAFQKKLVDQPAMAMVLADLALDQEAFAALAFRLALSFDEANGSGTEAAHARVLTPVAKFAVCKAAPAFIAETM
EVLGGNGYVEDCALPRLYREAPVNAIWEGSGNVMALDLARVAFREPDLVQAILANLKERTRGLPGAASTAETVSRCLQSG
DREAHARRAAEALALLAAAAALAESAPTAVTEAFAATRLATARGIYGANAIDAVRDLMLERTLAA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=265, Percent_Identity=29.4339622641509, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557235, Length=285, Percent_Identity=24.5614035087719, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI76496475, Length=285, Percent_Identity=24.5614035087719, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI226958414, Length=282, Percent_Identity=25.886524822695, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI226958412, Length=282, Percent_Identity=25.886524822695, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4501859, Length=243, Percent_Identity=26.3374485596708, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI7656849, Length=268, Percent_Identity=26.4925373134328, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI4557231, Length=271, Percent_Identity=27.3062730627306, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI187960098, Length=271, Percent_Identity=27.3062730627306, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI21361497, Length=288, Percent_Identity=22.9166666666667, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87082384, Length=543, Percent_Identity=44.5672191528545, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI87081958, Length=269, Percent_Identity=26.0223048327138, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786223, Length=270, Percent_Identity=23.3333333333333, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=448, Percent_Identity=30.5803571428571, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI86563383, Length=448, Percent_Identity=30.5803571428571, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17538396, Length=271, Percent_Identity=27.6752767527675, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=315, Percent_Identity=24.1269841269841, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=268, Percent_Identity=24.2537313432836, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=266, Percent_Identity=25.187969924812, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=268, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=248, Percent_Identity=23.7903225806452, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=328, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=271, Percent_Identity=28.0442804428044, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363737, Length=413, Percent_Identity=23.728813559322, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=284, Percent_Identity=26.4084507042254, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21355753, Length=295, Percent_Identity=24.7457627118644, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24660351, Length=335, Percent_Identity=25.0746268656716, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666513, Length=295, Percent_Identity=24.7457627118644, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 58034; Mature: 58034

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTHLADEVSNQPPPYGDINLAAGDPALAAASERAGMNGGAFAFGGQWGGSDQLALGRL
CCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHH
ANENPPELHSHDPQGRRCDVVEFHPAYHALMAQSMDAGLHCSSWDGPARPAEARRGNAQR
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCCHHH
ATRLYVVSQVEAGHVCPLTMTHAAPASLAAAPELLRDFLPRIRARNYDGRFVPFWEKASV
HEEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
TIGMSMTERQGGTDVRSNTTQAVPIGGSEYEITGAKWFLSAPMSDAFLVLAQAPGGLTAF
EEEEEECCCCCCCCCCCCCCEEEECCCCCEEEECCEEEEECCCCCEEEEEEECCCCEEEE
LMPRFRPDGSVNGVRLTRLKRKLGNRSNASCEVEFERAFAWRVGEEGRGIPTIIGMVQMT
ECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHEEEECCCCCCCCHHHHHHHHHH
RLDCAVSSAGLMRAALARALHHARHRTAFQKKLVDQPAMAMVLADLALDQEAFAALAFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHH
ALSFDEANGSGTEAAHARVLTPVAKFAVCKAAPAFIAETMEVLGGNGYVEDCALPRLYRE
HHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
APVNAIWEGSGNVMALDLARVAFREPDLVQAILANLKERTRGLPGAASTAETVSRCLQSG
CCCCEEEECCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
DREAHARRAAEALALLAAAAALAESAPTAVTEAFAATRLATARGIYGANAIDAVRDLMLE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RTLAA
HHHCC
>Mature Secondary Structure
MDFTHLADEVSNQPPPYGDINLAAGDPALAAASERAGMNGGAFAFGGQWGGSDQLALGRL
CCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHH
ANENPPELHSHDPQGRRCDVVEFHPAYHALMAQSMDAGLHCSSWDGPARPAEARRGNAQR
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCEECCCCCCCCCCHHHCCCHHH
ATRLYVVSQVEAGHVCPLTMTHAAPASLAAAPELLRDFLPRIRARNYDGRFVPFWEKASV
HEEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
TIGMSMTERQGGTDVRSNTTQAVPIGGSEYEITGAKWFLSAPMSDAFLVLAQAPGGLTAF
EEEEEECCCCCCCCCCCCCCEEEECCCCCEEEECCEEEEECCCCCEEEEEEECCCCEEEE
LMPRFRPDGSVNGVRLTRLKRKLGNRSNASCEVEFERAFAWRVGEEGRGIPTIIGMVQMT
ECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHEEEECCCCCCCCHHHHHHHHHH
RLDCAVSSAGLMRAALARALHHARHRTAFQKKLVDQPAMAMVLADLALDQEAFAALAFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHH
ALSFDEANGSGTEAAHARVLTPVAKFAVCKAAPAFIAETMEVLGGNGYVEDCALPRLYRE
HHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
APVNAIWEGSGNVMALDLARVAFREPDLVQAILANLKERTRGLPGAASTAETVSRCLQSG
CCCCEEEECCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
DREAHARRAAEALALLAAAAALAESAPTAVTEAFAATRLATARGIYGANAIDAVRDLMLE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RTLAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]