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The map label for this gene is argD [H]

Identifier: 154245166

GI number: 154245166

Start: 1401142

End: 1402350

Strand: Direct

Name: argD [H]

Synonym: Xaut_1218

Alternate gene names: 154245166

Gene position: 1401142-1402350 (Clockwise)

Preceding gene: 154245164

Following gene: 154245167

Centisome position: 26.39

GC content: 68.65

Gene sequence:

>1209_bases
GTGATCACCGCCGTTCTGCCGACCTATGCGCGCATCGACCTCGAATTCGAACGGGGGGAGGGCTGCTGGCTCGTCACGAC
GGACGGGCGACGCTTTCTCGATTTCACCGGCGGCATCGCGGTGAACGTGCTGGGCCACGCCCATCCCTATCTCGCCGAGG
CGCTCTCCGAGCAGGCGAAGAAGCTCTGGCACACCTCGAACCTGTTCCGCATCCCCGGCGGCGAGCGGCTCGCGGATCGC
ATCAAGGCGGTGACCTTCGCGGACACCATGTTCTTCACCAATTCCGGTGCGGAAGCCCTTGAGTGCGCCATCAAGATGGC
CCGCAAGTATCAGTTCGCCAGCGGCCATCCGGAGAAGAACCGCATCATTACCTTCGAAGGCGCCTTCCACGGCCGCACGC
TGGCGACCATCGCCGCCGGTGGCAACGCCAAGTATCTCGAAGGCTTCGGGCCGGCCATGCCGGGCTTCGACCAGGTGCCG
TTCGGCGACCTGGACGCCGCCCGCGCCGCCGTGACGCCTGAGACCGCCGCCATTCTGGTGGAGCCGGTGCAGGGCGAGGG
CGGCGTGCGCGTTCCTCCCTCCGGCTTCCTCAAGGGGCTGCGCGCCTTGTGCGACGAGAAGGGCCTCCTGCTTGTGCTGG
ACGAGGTGCAGTGCGGGGTTGGGCGCACCGGCAAGCTGTTCGCGCACGAATGGGTCGGTGTCACCCCGGATATCATGGCG
GTGGCCAAGGGCATCGGCGGCGGCTTTCCCATGGGCGCGTGCCTTGCCACGGAAGAGGCCGCCAAGGGCATGACGCTCGG
CACCCATGGCTCCACCTATGGCGGCAATCCGCTGGCCATGGCGGTGGGCAATGCGGTGCTCGACCTCGTGCTCGCCGACG
GCTTCCTCGACCATGTGAACGCCATGTCGACGCGCCTCGTGCAGCGCCTCGCCGAGGTCAGGGACCGGCATCCTTCGGTC
ATCGCCGAGGTGCGCGGCCAGGGCCTGCTGCTGGGCCTGCGCTGCGCCGTGCCGGCCGCCGACCTCGTCACGGCCCTGCG
TGAGGAAGGCATGCTCGCGCCCGGCGCCAGCGACAATGTGGTGCGGCTGTTGCCCCCGCTCATCGTGAGCGAGGAGGAGG
TGGGCATCGCCGTGGAGAAGATCGAAGCTGCCTGCCGGCGTATCGAGGACCGCCTCGTCGCCGCTCCGGTGCAGGGAGCG
GCGGAATGA

Upstream 100 bases:

>100_bases
GCTTGGGCGGCCTTTTTTGTTTGCCACGTGCCGGTTGTCGCGTTTTGTTCGTCAACCGGTGCCACCTCAAGGGGAATGAA
CCCTTTTTGGGAGGTTTGAA

Downstream 100 bases:

>100_bases
AGGGGAACGGCGTGCGCCATTTTCTAGACCTGTCCGAGATCCCGGCCGAGGAGTTGCGCCGGGTTCTCGATTTTTCCAAG
GACCTCAAGGCCCGGCGCAA

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MITAVLPTYARIDLEFERGEGCWLVTTDGRRFLDFTGGIAVNVLGHAHPYLAEALSEQAKKLWHTSNLFRIPGGERLADR
IKAVTFADTMFFTNSGAEALECAIKMARKYQFASGHPEKNRIITFEGAFHGRTLATIAAGGNAKYLEGFGPAMPGFDQVP
FGDLDAARAAVTPETAAILVEPVQGEGGVRVPPSGFLKGLRALCDEKGLLLVLDEVQCGVGRTGKLFAHEWVGVTPDIMA
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDLVLADGFLDHVNAMSTRLVQRLAEVRDRHPSV
IAEVRGQGLLLGLRCAVPAADLVTALREEGMLAPGASDNVVRLLPPLIVSEEEVGIAVEKIEAACRRIEDRLVAAPVQGA
AE

Sequences:

>Translated_402_residues
MITAVLPTYARIDLEFERGEGCWLVTTDGRRFLDFTGGIAVNVLGHAHPYLAEALSEQAKKLWHTSNLFRIPGGERLADR
IKAVTFADTMFFTNSGAEALECAIKMARKYQFASGHPEKNRIITFEGAFHGRTLATIAAGGNAKYLEGFGPAMPGFDQVP
FGDLDAARAAVTPETAAILVEPVQGEGGVRVPPSGFLKGLRALCDEKGLLLVLDEVQCGVGRTGKLFAHEWVGVTPDIMA
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDLVLADGFLDHVNAMSTRLVQRLAEVRDRHPSV
IAEVRGQGLLLGLRCAVPAADLVTALREEGMLAPGASDNVVRLLPPLIVSEEEVGIAVEKIEAACRRIEDRLVAAPVQGA
AE
>Mature_402_residues
MITAVLPTYARIDLEFERGEGCWLVTTDGRRFLDFTGGIAVNVLGHAHPYLAEALSEQAKKLWHTSNLFRIPGGERLADR
IKAVTFADTMFFTNSGAEALECAIKMARKYQFASGHPEKNRIITFEGAFHGRTLATIAAGGNAKYLEGFGPAMPGFDQVP
FGDLDAARAAVTPETAAILVEPVQGEGGVRVPPSGFLKGLRALCDEKGLLLVLDEVQCGVGRTGKLFAHEWVGVTPDIMA
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDLVLADGFLDHVNAMSTRLVQRLAEVRDRHPSV
IAEVRGQGLLLGLRCAVPAADLVTALREEGMLAPGASDNVVRLLPPLIVSEEEVGIAVEKIEAACRRIEDRLVAAPVQGA
AE

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=34.8958333333333, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=37.248322147651, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=30.1123595505618, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=26.0765550239234, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=26.2019230769231, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=26.8929503916449, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=25.3588516746411, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI188536080, Length=426, Percent_Identity=23.4741784037559, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38679950, Length=426, Percent_Identity=23.4741784037559, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38679946, Length=426, Percent_Identity=23.4741784037559, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=46.2915601023018, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=43.0412371134021, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI145693181, Length=382, Percent_Identity=35.3403141361257, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789016, Length=400, Percent_Identity=35.75, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=34.3283582089552, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=31.5789473684211, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=32.02416918429, Blast_Score=138, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=33.6842105263158, Blast_Score=231, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=29.7482837528604, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=28.3980582524272, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=442, Percent_Identity=23.9819004524887, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=30.0613496932515, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=37.4371859296482, Blast_Score=267, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=31.75, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=426, Percent_Identity=24.1784037558685, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=436, Percent_Identity=23.6238532110092, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=32.8947368421053, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=32.2799097065463, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28574759, Length=441, Percent_Identity=31.7460317460317, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=27.6442307692308, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281366494, Length=433, Percent_Identity=24.4803695150115, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24667139, Length=433, Percent_Identity=24.4803695150115, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24667143, Length=433, Percent_Identity=24.4803695150115, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42519; Mature: 42519

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAVLPTYARIDLEFERGEGCWLVTTDGRRFLDFTGGIAVNVLGHAHPYLAEALSEQAK
CCEEECCCEEEEEEEEECCCEEEEEECCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHH
KLWHTSNLFRIPGGERLADRIKAVTFADTMFFTNSGAEALECAIKMARKYQFASGHPEKN
HHHHCCCEEECCCCHHHHHHHHHHEEEHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
RIITFEGAFHGRTLATIAAGGNAKYLEGFGPAMPGFDQVPFGDLDAARAAVTPETAAILV
EEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEE
EPVQGEGGVRVPPSGFLKGLRALCDEKGLLLVLDEVQCGVGRTGKLFAHEWVGVTPDIMA
EEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEHHCCCCCHHHHH
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDLVLADGFLDHVN
HHHHCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AMSTRLVQRLAEVRDRHPSVIAEVRGQGLLLGLRCAVPAADLVTALREEGMLAPGASDNV
HHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
VRLLPPLIVSEEEVGIAVEKIEAACRRIEDRLVAAPVQGAAE
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MITAVLPTYARIDLEFERGEGCWLVTTDGRRFLDFTGGIAVNVLGHAHPYLAEALSEQAK
CCEEECCCEEEEEEEEECCCEEEEEECCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHH
KLWHTSNLFRIPGGERLADRIKAVTFADTMFFTNSGAEALECAIKMARKYQFASGHPEKN
HHHHCCCEEECCCCHHHHHHHHHHEEEHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
RIITFEGAFHGRTLATIAAGGNAKYLEGFGPAMPGFDQVPFGDLDAARAAVTPETAAILV
EEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEE
EPVQGEGGVRVPPSGFLKGLRALCDEKGLLLVLDEVQCGVGRTGKLFAHEWVGVTPDIMA
EEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEHHCCCCCHHHHH
VAKGIGGGFPMGACLATEEAAKGMTLGTHGSTYGGNPLAMAVGNAVLDLVLADGFLDHVN
HHHHCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AMSTRLVQRLAEVRDRHPSVIAEVRGQGLLLGLRCAVPAADLVTALREEGMLAPGASDNV
HHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
VRLLPPLIVSEEEVGIAVEKIEAACRRIEDRLVAAPVQGAAE
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]