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The map label for this gene is ftsW [H]

Identifier: 154245138

GI number: 154245138

Start: 1368892

End: 1370091

Strand: Direct

Name: ftsW [H]

Synonym: Xaut_1190

Alternate gene names: 154245138

Gene position: 1368892-1370091 (Clockwise)

Preceding gene: 154245137

Following gene: 154245139

Centisome position: 25.78

GC content: 67.92

Gene sequence:

>1200_bases
ATGATGTCGCGCGCCGACCGCACCGTCTTGAGCGAATGGTGGTGGACGGTGGACCGCGCCCTTTTGGCCGCCCTCTGCGG
CCTGATGGTGATCGGTATCATCCTGTGCCTTGCCGCAAGCCCGGCGGTGGCCGCGCGCCTCGGCATCGCTGACCCGTTCC
ATTTCGTGAACCGGCAGGTGCTGTTCCTGGTGCCGGCCGCGGTGGTGATGATCGCCACCTCCTTCCTGTCGCCGCGCGCG
CTCAGGCGCATCTGCATGGTGGTGTTCGCCATCTTCTTCGTGCTGCTCATGGCCACCCTGGTGGTGGGACCGGAGGTGAA
GGGCGCGCGGCGCTGGCTCACCATCGCCGGCGTCACCGTGCAGCCGTCCGAATTCATCAAGCCGGCCTTCGTCATCCTCG
CCGCCTGGCTGTTCGCCGAGAGCACGCGGCGGCCGGAGATGCCGGCCACCCTGCTGGCGTTCGGCCTGCTCGGCAGCGTG
CTGGGCCTTTTGGTGAAGCAGCCGGACTTCGGCCAGAGCCTTTTGATCTCGCTGGTGTGGGCGTCCCTGTTCTTCCTCGC
CGGGCTGCGCTGGATCTGGATGGTGGGGCTGGTGGGCGTGGGCGCGGGCGGCGGCTTTATCGCCTACATGACCGTGTCCC
ACGTGCAGAAGCGCATCAACCGCTTCCTCAATCCCGACTCGGGCGACACCTACCAGATCGACGCCGCGCTCAATTCCTTC
CGCAATGGCGGCTGGTTCGGCCAGGGGCCGGGCGAGGGCACCATGAAGCGCATGCTTCCGGACGGGCACACCGACTTCGT
CTTCGCCGTGGCGGCGGAGGAGTTCGGGATCATCCTGTGCCTCATCATCCTCGCTTTGTTCGCCTTCATCATCCTGCGGT
CGCTGTCGCGGGCCTCGAAGGAGAGCGATCCCTTCTCCCGCTTCGCCATCACCGGGCTTGCCCTGCTGTTCGGGCTGCAG
GCAGCCATCAACATGGCGGTGAACGTGCACATCGCCCCGGCCAAGGGCATGACGCTGCCGTTCATCTCCTATGGCGGCTC
CTCGCTTATCTCCATCGCCTTCGGCATGGGCATGCTGCTGGCCCTCTCGCGCAAGCGGCCCGGCGCGGCGGCGTTGGCGG
CCCTCACCGAGAAGCCGGCGGTGGAGCCTGTGGCACAGCCGGTCGCGCCGCCGGCCGGCGCCATGCCGGACCCGGCCTGA

Upstream 100 bases:

>100_bases
TGTGGCGCTTCGTCCGCGGCAAGGGGATGGGGTCTTAATCGCTCGTCAACCGTCCCGGACGCATGGTGCGGCAGATGTTC
CGCACCGGAGTGGCCTTCCC

Downstream 100 bases:

>100_bases
GCCCGCGCGGCGCCTGAGCGGAGGGATCGCGGATGCGTCAGCATCCTTGCGATCCGACCCGACAAGCCCGCGCGGCGCCT
GAGCGAGGGGGTCGCGGATG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MMSRADRTVLSEWWWTVDRALLAALCGLMVIGIILCLAASPAVAARLGIADPFHFVNRQVLFLVPAAVVMIATSFLSPRA
LRRICMVVFAIFFVLLMATLVVGPEVKGARRWLTIAGVTVQPSEFIKPAFVILAAWLFAESTRRPEMPATLLAFGLLGSV
LGLLVKQPDFGQSLLISLVWASLFFLAGLRWIWMVGLVGVGAGGGFIAYMTVSHVQKRINRFLNPDSGDTYQIDAALNSF
RNGGWFGQGPGEGTMKRMLPDGHTDFVFAVAAEEFGIILCLIILALFAFIILRSLSRASKESDPFSRFAITGLALLFGLQ
AAINMAVNVHIAPAKGMTLPFISYGGSSLISIAFGMGMLLALSRKRPGAAALAALTEKPAVEPVAQPVAPPAGAMPDPA

Sequences:

>Translated_399_residues
MMSRADRTVLSEWWWTVDRALLAALCGLMVIGIILCLAASPAVAARLGIADPFHFVNRQVLFLVPAAVVMIATSFLSPRA
LRRICMVVFAIFFVLLMATLVVGPEVKGARRWLTIAGVTVQPSEFIKPAFVILAAWLFAESTRRPEMPATLLAFGLLGSV
LGLLVKQPDFGQSLLISLVWASLFFLAGLRWIWMVGLVGVGAGGGFIAYMTVSHVQKRINRFLNPDSGDTYQIDAALNSF
RNGGWFGQGPGEGTMKRMLPDGHTDFVFAVAAEEFGIILCLIILALFAFIILRSLSRASKESDPFSRFAITGLALLFGLQ
AAINMAVNVHIAPAKGMTLPFISYGGSSLISIAFGMGMLLALSRKRPGAAALAALTEKPAVEPVAQPVAPPAGAMPDPA
>Mature_399_residues
MMSRADRTVLSEWWWTVDRALLAALCGLMVIGIILCLAASPAVAARLGIADPFHFVNRQVLFLVPAAVVMIATSFLSPRA
LRRICMVVFAIFFVLLMATLVVGPEVKGARRWLTIAGVTVQPSEFIKPAFVILAAWLFAESTRRPEMPATLLAFGLLGSV
LGLLVKQPDFGQSLLISLVWASLFFLAGLRWIWMVGLVGVGAGGGFIAYMTVSHVQKRINRFLNPDSGDTYQIDAALNSF
RNGGWFGQGPGEGTMKRMLPDGHTDFVFAVAAEEFGIILCLIILALFAFIILRSLSRASKESDPFSRFAITGLALLFGLQ
AAINMAVNVHIAPAKGMTLPFISYGGSSLISIAFGMGMLLALSRKRPGAAALAALTEKPAVEPVAQPVAPPAGAMPDPA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=357, Percent_Identity=32.4929971988796, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786853, Length=310, Percent_Identity=32.5806451612903, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42718; Mature: 42718

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSRADRTVLSEWWWTVDRALLAALCGLMVIGIILCLAASPAVAARLGIADPFHFVNRQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCHH
LFLVPAAVVMIATSFLSPRALRRICMVVFAIFFVLLMATLVVGPEVKGARRWLTIAGVTV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCEE
QPSEFIKPAFVILAAWLFAESTRRPEMPATLLAFGLLGSVLGLLVKQPDFGQSLLISLVW
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ASLFFLAGLRWIWMVGLVGVGAGGGFIAYMTVSHVQKRINRFLNPDSGDTYQIDAALNSF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHC
RNGGWFGQGPGEGTMKRMLPDGHTDFVFAVAAEEFGIILCLIILALFAFIILRSLSRASK
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESDPFSRFAITGLALLFGLQAAINMAVNVHIAPAKGMTLPFISYGGSSLISIAFGMGMLL
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHH
ALSRKRPGAAALAALTEKPAVEPVAQPVAPPAGAMPDPA
HHHCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MMSRADRTVLSEWWWTVDRALLAALCGLMVIGIILCLAASPAVAARLGIADPFHFVNRQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCHH
LFLVPAAVVMIATSFLSPRALRRICMVVFAIFFVLLMATLVVGPEVKGARRWLTIAGVTV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEECCEE
QPSEFIKPAFVILAAWLFAESTRRPEMPATLLAFGLLGSVLGLLVKQPDFGQSLLISLVW
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ASLFFLAGLRWIWMVGLVGVGAGGGFIAYMTVSHVQKRINRFLNPDSGDTYQIDAALNSF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHC
RNGGWFGQGPGEGTMKRMLPDGHTDFVFAVAAEEFGIILCLIILALFAFIILRSLSRASK
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESDPFSRFAITGLALLFGLQAAINMAVNVHIAPAKGMTLPFISYGGSSLISIAFGMGMLL
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHH
ALSRKRPGAAALAALTEKPAVEPVAQPVAPPAGAMPDPA
HHHCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]