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The map label for this gene is 154245103

Identifier: 154245103

GI number: 154245103

Start: 1328213

End: 1329184

Strand: Reverse

Name: 154245103

Synonym: Xaut_1155

Alternate gene names: NA

Gene position: 1329184-1328213 (Counterclockwise)

Preceding gene: 154245104

Following gene: 154245102

Centisome position: 25.04

GC content: 69.03

Gene sequence:

>972_bases
ATGCACGGCCAGGGCGCACGGCTCAGGGAGACGCCAAGGCTCATGCACACGCTGCTTGTTACCCATCCTGCCGGCCTCAA
CCATGTGACCCCGCCCGGACATCCCGAGCGGCCGGACCGGTTGCGCGCCCTCGACCGTATCTTCGAGCAGGAGAAGTTCA
CCCACCTCATCCGCGACCTCGCCCCCCTCGGCGCGCGCGAGGACATCATCCGCGTCCATCCCGGCGACTTCGTCGATGCC
ATGGGCGAGGCTTCGCCTAAGGACGGGCTGGTGCGCATCGATTCGGATACGGTGCTGTCCCCCGGCAGCTGGGAAGCGGC
CCTGCGCGCGGTGGGCGGCGCCTGCTACGCGGTGGACGAGGTGCTGGAAGGCAAGGTGCAGAACGCCTTCGTCGCCATGC
GCCCGCCGGGCCACCATTGCGAGACCCGCAAGCCCATGGGCTTCTGCCTGCTCAACCAGGTGGCCATCGCCGCCCGCCAC
GCCCAGGCGAAATTCGGCCTCGGCCGGGTCGCCATCGTGGATTTCGACGTGCACCACGGCAACGGCACCCAGGACATCTT
CTGGGCCGACGACAGCGTGCTCTACTGCTCCACCCACGAGATGCCGCTCTATCCCGGCACCGGCGCCGTGAGCGAGACCG
GGGACGCCAACACCATCGTCAACGCCCCGCTGCGCTCGGGCGACGACGGAGCGGTGTTCAAGGAGGCCATGGAAACGCGC
ATCCTGCCGCGCATCTCCGCCTTCTCGCCGGACCTGATCCTGATCTCGGCCGGCTTCGACGCCCATATCCGCGATCCGCT
GGCCTCGCTGCGCCTGGTGGACACCGACTTCGGCTGGGTCACCCGCCGGCTGATGGAAGTGGCCGACGCCACCTGCCAGG
GGCGTGTCGTGTCGGTGCTGGAAGGCGGCTACGATCTGGAAGGCCTCGCCTCCTCCGCCGCCGCGCACGTCTGCGCGCTT
ATGCACGGCTGA

Upstream 100 bases:

>100_bases
AAACCGCTTCTTGATCCGGCGCAACACCCTGCCCCAAGCGCTGGAATATGGTATGTCAAGGACAACAGGCGAAAACGCCG
GAAACCAAGCCAAGGCCAAG

Downstream 100 bases:

>100_bases
GGGGGGCTTCGGCGGGCCGCCCGCCGAAGCGATCTTCGCGGCGGAAAGACACCGGCCGTCGCGATCCGAGGAGCTGTTGC
CGTGAACCGCGTCCGCTCTC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHGQGARLRETPRLMHTLLVTHPAGLNHVTPPGHPERPDRLRALDRIFEQEKFTHLIRDLAPLGAREDIIRVHPGDFVDA
MGEASPKDGLVRIDSDTVLSPGSWEAALRAVGGACYAVDEVLEGKVQNAFVAMRPPGHHCETRKPMGFCLLNQVAIAARH
AQAKFGLGRVAIVDFDVHHGNGTQDIFWADDSVLYCSTHEMPLYPGTGAVSETGDANTIVNAPLRSGDDGAVFKEAMETR
ILPRISAFSPDLILISAGFDAHIRDPLASLRLVDTDFGWVTRRLMEVADATCQGRVVSVLEGGYDLEGLASSAAAHVCAL
MHG

Sequences:

>Translated_323_residues
MHGQGARLRETPRLMHTLLVTHPAGLNHVTPPGHPERPDRLRALDRIFEQEKFTHLIRDLAPLGAREDIIRVHPGDFVDA
MGEASPKDGLVRIDSDTVLSPGSWEAALRAVGGACYAVDEVLEGKVQNAFVAMRPPGHHCETRKPMGFCLLNQVAIAARH
AQAKFGLGRVAIVDFDVHHGNGTQDIFWADDSVLYCSTHEMPLYPGTGAVSETGDANTIVNAPLRSGDDGAVFKEAMETR
ILPRISAFSPDLILISAGFDAHIRDPLASLRLVDTDFGWVTRRLMEVADATCQGRVVSVLEGGYDLEGLASSAAAHVCAL
MHG
>Mature_323_residues
MHGQGARLRETPRLMHTLLVTHPAGLNHVTPPGHPERPDRLRALDRIFEQEKFTHLIRDLAPLGAREDIIRVHPGDFVDA
MGEASPKDGLVRIDSDTVLSPGSWEAALRAVGGACYAVDEVLEGKVQNAFVAMRPPGHHCETRKPMGFCLLNQVAIAARH
AQAKFGLGRVAIVDFDVHHGNGTQDIFWADDSVLYCSTHEMPLYPGTGAVSETGDANTIVNAPLRSGDDGAVFKEAMETR
ILPRISAFSPDLILISAGFDAHIRDPLASLRLVDTDFGWVTRRLMEVADATCQGRVVSVLEGGYDLEGLASSAAAHVCAL
MHG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI153085395, Length=247, Percent_Identity=41.2955465587045, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI30795202, Length=302, Percent_Identity=36.4238410596026, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI62750347, Length=247, Percent_Identity=41.2955465587045, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI62750349, Length=247, Percent_Identity=41.2955465587045, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI17158039, Length=302, Percent_Identity=36.4238410596026, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI30795204, Length=302, Percent_Identity=36.4238410596026, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI13128864, Length=301, Percent_Identity=37.5415282392027, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI20070354, Length=301, Percent_Identity=36.8770764119601, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI169234807, Length=246, Percent_Identity=39.0243902439024, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI148539870, Length=246, Percent_Identity=39.0243902439024, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI226529806, Length=301, Percent_Identity=33.5548172757475, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI13128862, Length=254, Percent_Identity=25.9842519685039, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI13128860, Length=266, Percent_Identity=24.4360902255639, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI8923769, Length=206, Percent_Identity=26.6990291262136, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI293336691, Length=266, Percent_Identity=24.0601503759398, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI262073088, Length=169, Percent_Identity=28.4023668639053, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=33.974358974359, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI193206283, Length=312, Percent_Identity=33.974358974359, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17540332, Length=312, Percent_Identity=33.974358974359, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI193209491, Length=246, Percent_Identity=40.650406504065, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25154020, Length=305, Percent_Identity=30.1639344262295, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=308, Percent_Identity=29.5454545454545, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17537347, Length=311, Percent_Identity=32.1543408360129, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17508561, Length=266, Percent_Identity=24.4360902255639, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17534739, Length=306, Percent_Identity=25.1633986928105, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=312, Percent_Identity=33.0128205128205, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6325141, Length=327, Percent_Identity=26.605504587156, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323999, Length=262, Percent_Identity=26.3358778625954, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=257, Percent_Identity=24.9027237354086, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=170, Percent_Identity=25.8823529411765, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24642146, Length=294, Percent_Identity=35.0340136054422, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642142, Length=294, Percent_Identity=35.0340136054422, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281360899, Length=294, Percent_Identity=35.7142857142857, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642144, Length=294, Percent_Identity=35.0340136054422, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24641720, Length=251, Percent_Identity=36.2549800796813, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360799, Length=251, Percent_Identity=36.2549800796813, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360801, Length=251, Percent_Identity=36.2549800796813, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24657891, Length=266, Percent_Identity=24.4360902255639, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644244, Length=301, Percent_Identity=24.5847176079734, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34941; Mature: 34941

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGQGARLRETPRLMHTLLVTHPAGLNHVTPPGHPERPDRLRALDRIFEQEKFTHLIRDL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
APLGAREDIIRVHPGDFVDAMGEASPKDGLVRIDSDTVLSPGSWEAALRAVGGACYAVDE
HCCCCCCCEEEECCCHHHHHHCCCCCCCCEEEECCCCEECCCCHHHHHHHHCCHHHHHHH
VLEGKVQNAFVAMRPPGHHCETRKPMGFCLLNQVAIAARHAQAKFGLGRVAIVDFDVHHG
HHHCHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECC
NGTQDIFWADDSVLYCSTHEMPLYPGTGAVSETGDANTIVNAPLRSGDDGAVFKEAMETR
CCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
ILPRISAFSPDLILISAGFDAHIRDPLASLRLVDTDFGWVTRRLMEVADATCQGRVVSVL
HCCHHHCCCCCEEEEECCCCCHHHCCHHHEEEEECCHHHHHHHHHHHHCCCCCCCEEEEC
EGGYDLEGLASSAAAHVCALMHG
CCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHGQGARLRETPRLMHTLLVTHPAGLNHVTPPGHPERPDRLRALDRIFEQEKFTHLIRDL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
APLGAREDIIRVHPGDFVDAMGEASPKDGLVRIDSDTVLSPGSWEAALRAVGGACYAVDE
HCCCCCCCEEEECCCHHHHHHCCCCCCCCEEEECCCCEECCCCHHHHHHHHCCHHHHHHH
VLEGKVQNAFVAMRPPGHHCETRKPMGFCLLNQVAIAARHAQAKFGLGRVAIVDFDVHHG
HHHCHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECC
NGTQDIFWADDSVLYCSTHEMPLYPGTGAVSETGDANTIVNAPLRSGDDGAVFKEAMETR
CCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHH
ILPRISAFSPDLILISAGFDAHIRDPLASLRLVDTDFGWVTRRLMEVADATCQGRVVSVL
HCCHHHCCCCCEEEEECCCCCHHHCCHHHEEEEECCHHHHHHHHHHHHCCCCCCCEEEEC
EGGYDLEGLASSAAAHVCALMHG
CCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]