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The map label for this gene is dctB [H]

Identifier: 154245064

GI number: 154245064

Start: 1285440

End: 1287563

Strand: Direct

Name: dctB [H]

Synonym: Xaut_1116

Alternate gene names: 154245064

Gene position: 1285440-1287563 (Clockwise)

Preceding gene: 154245063

Following gene: 154245071

Centisome position: 24.21

GC content: 68.22

Gene sequence:

>2124_bases
ATGGCGGCAAGGATGAAGGGGCCTGAGGCACTGGGCGACGGCTTGCGGGGGCTGGTCAATCCGGTCACGCTGATGCTGGT
CGGCCTCGTGGTCCTGGTCGGCGTCATCCCGTTCGTCGCGGCGCTGGCGCTGTACCAGATGCATGACCGGGCCGAACGGG
ACGAGGCGGTGGCCGACGCCCGGCGCACCGCGACACTGCTGCTGCGCAGCTTCGAGCAATCCATCGCGCCGGTCGACCTT
CTGCTCCTGAATATCGCCAGCACGTATGACGCATCCGCCTCGCCGGTGCAGGTTCATACCATGCTGCGCAGCATCAACCT
GCCTCCGGCCGTGCTCCAGGTGACCATCACCGACAAGGCGGGGATGTTGATCGCCAGCAGCCTGCCCACCGACGGCATGG
AGCAGAAGGACCTGTCGGGCCGCGAGTACATGCGCGCCTACCTCGGCAGGGAAGCTGTCCATGCGGGGCTCTCCATCGGC
AAGCCGGTGCTGGGCCTGCTGTCGAAGAAGTGGGGGATCCCGCTCGCTCGGCCGCTCGTCGACGCGGAAGGCCGGTTTGC
CGGCGTGGCGGTTGCGTCGTACGCGATCAGCGACTTCATCGACTTCTACAAGCAACTGCGAACCGAGGACGACATGCTGA
TCGCCCTCGTCGGCCGCGATGGCATCGTTCGCGCCCGCGCGGCCCGCGCCACCAGCTTCGGCGAAGACGTTTCCGCAAGC
CGGGCCTTCCGGCAAACCATCGCGAACGGGGCGGTCGTCTATGACGAAGTGAGTGTCTTCGACGGCGTAGCGCGGGTGGG
ATACGCCGTTGCCTCGACGAAATACCCTATCCTGGTGACGGTGGCTCACTCGCTGGCCGCCGTGGAGCAGCGGTCGAAGG
AGTTCCGCGCCGCCATCTGGAGCACGGCGATCGGGCTGTCCGTGGCGCTGTTCATCGTCGCGCTTCTGGCCGGGCGCTAC
CTGAAACTGCAGAAAAAGCTGAAGGCCAATGAGGTGCAGGCCCTGGCGCGCCAGCGCGAGGCCAACGTGCTCGAAGCCAT
CAGCCGGGTGCCCGGCGTCGCCGTCATGCACGTCACCGAAGCCGGCGCCAGCGAGGTGGGCACCGCCGCCGATCCGACCC
TGTCACCCTTGGTGCGCCGCTATCTCGCCAGCGGCCGGTTTCGCAACCTGGTCCGCGGCCTGAAGGAGCCGCAGCTGCGC
GACGAGCATCTGTCCGACGGCACCAGCGAGCTGGAAGTGGAGATGGTGGTGGCGCCGCTCCAGGACATCGATCGCGCCGC
ATCGCCCGGGCAGGGGGGCGACATGGTGGTGTTCGCCGTGGACCGCACCCAGCGGCGGATGGAGGAGAACAAGCTCTACC
AGATGTCGAAGCTTGCCTCCCTCGGCGAGGTGGCGACGGGGCTTGCCCACGAGATCAACCAGCCCCTCGGCGTCATCCGG
CTGGCCGCGTCCAACGCCCTGACCGGCCTGAAGGTGGGGCTGCCGCCCGATCATCTCGCCGGCAAGCTCGACCGCATCAT
CCAGCAGACGGTGCGCATGAGCCGCATCATCGACCACATGCGCATCTTCGGCCGCAAGAGCGAGGAGCAGCTTCAGCCGT
CGCAGCCCACCCAGGCGGTGGAGGGCGCGCTGCAGGTGGTGGGTGCCCATTTCCGGCTCGACGAGATCGAGGTGAACACC
ATGTCCGAGCCCCACCTGCCGGACGTGCTCTGCCGCCAGGACCAGCTGGAGCAGGTGATCATCAACCTGCTGCAGAATGC
CCGCGACGCCATCAACGAGCGCCGCGCCGCATTGGGCGAGCACTTCGCCGGCCGCATCGCGGTGCGCGTCGCCGGCGAGG
CGAGGATCGGCGCGCCGGAGCAGGTGCTGATCGAGGTCGCCGACAATGGTGGCGGCATTCCGGAAGAGGTGGTGGAGCGC
ATCTTCCAGCCGTTCTTCACCACCAAGCCGCCGGGCAAGGGCACCGGCCTTGGCCTGTCGGTGAGCTTCGGCATCATCCG
CGACCACGGCGGCAGCCTCTCGGTCCGCAACGGGTCCGAGGGCGCCATTTTCAGCATCCGCCTTCCGGCCCGGCTGGCCG
CGCCGGCCCTGATCGGCGCCAGCGCCGAGATCGTGCAAGGCTGA

Upstream 100 bases:

>100_bases
GCCCCCGGCGATATCGCACAGGCGCTCGCGGCCGGCGTGGTGCGATGCTTTCGCAAGCCGCTGGCCTTCGAGGACCTGTG
TGCGGCGCTGGTGGAACTGG

Downstream 100 bases:

>100_bases
CCACGCGAGGCTGACCGCGCAAGGCTGATGCCTCCTGCGGCGAGCGTCCGGAGGCGGCCGTCGCGCGCCTTCACTCCGCG
GCGGAGCGCATCTCCGTGGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MAARMKGPEALGDGLRGLVNPVTLMLVGLVVLVGVIPFVAALALYQMHDRAERDEAVADARRTATLLLRSFEQSIAPVDL
LLLNIASTYDASASPVQVHTMLRSINLPPAVLQVTITDKAGMLIASSLPTDGMEQKDLSGREYMRAYLGREAVHAGLSIG
KPVLGLLSKKWGIPLARPLVDAEGRFAGVAVASYAISDFIDFYKQLRTEDDMLIALVGRDGIVRARAARATSFGEDVSAS
RAFRQTIANGAVVYDEVSVFDGVARVGYAVASTKYPILVTVAHSLAAVEQRSKEFRAAIWSTAIGLSVALFIVALLAGRY
LKLQKKLKANEVQALARQREANVLEAISRVPGVAVMHVTEAGASEVGTAADPTLSPLVRRYLASGRFRNLVRGLKEPQLR
DEHLSDGTSELEVEMVVAPLQDIDRAASPGQGGDMVVFAVDRTQRRMEENKLYQMSKLASLGEVATGLAHEINQPLGVIR
LAASNALTGLKVGLPPDHLAGKLDRIIQQTVRMSRIIDHMRIFGRKSEEQLQPSQPTQAVEGALQVVGAHFRLDEIEVNT
MSEPHLPDVLCRQDQLEQVIINLLQNARDAINERRAALGEHFAGRIAVRVAGEARIGAPEQVLIEVADNGGGIPEEVVER
IFQPFFTTKPPGKGTGLGLSVSFGIIRDHGGSLSVRNGSEGAIFSIRLPARLAAPALIGASAEIVQG

Sequences:

>Translated_707_residues
MAARMKGPEALGDGLRGLVNPVTLMLVGLVVLVGVIPFVAALALYQMHDRAERDEAVADARRTATLLLRSFEQSIAPVDL
LLLNIASTYDASASPVQVHTMLRSINLPPAVLQVTITDKAGMLIASSLPTDGMEQKDLSGREYMRAYLGREAVHAGLSIG
KPVLGLLSKKWGIPLARPLVDAEGRFAGVAVASYAISDFIDFYKQLRTEDDMLIALVGRDGIVRARAARATSFGEDVSAS
RAFRQTIANGAVVYDEVSVFDGVARVGYAVASTKYPILVTVAHSLAAVEQRSKEFRAAIWSTAIGLSVALFIVALLAGRY
LKLQKKLKANEVQALARQREANVLEAISRVPGVAVMHVTEAGASEVGTAADPTLSPLVRRYLASGRFRNLVRGLKEPQLR
DEHLSDGTSELEVEMVVAPLQDIDRAASPGQGGDMVVFAVDRTQRRMEENKLYQMSKLASLGEVATGLAHEINQPLGVIR
LAASNALTGLKVGLPPDHLAGKLDRIIQQTVRMSRIIDHMRIFGRKSEEQLQPSQPTQAVEGALQVVGAHFRLDEIEVNT
MSEPHLPDVLCRQDQLEQVIINLLQNARDAINERRAALGEHFAGRIAVRVAGEARIGAPEQVLIEVADNGGGIPEEVVER
IFQPFFTTKPPGKGTGLGLSVSFGIIRDHGGSLSVRNGSEGAIFSIRLPARLAAPALIGASAEIVQG
>Mature_706_residues
AARMKGPEALGDGLRGLVNPVTLMLVGLVVLVGVIPFVAALALYQMHDRAERDEAVADARRTATLLLRSFEQSIAPVDLL
LLNIASTYDASASPVQVHTMLRSINLPPAVLQVTITDKAGMLIASSLPTDGMEQKDLSGREYMRAYLGREAVHAGLSIGK
PVLGLLSKKWGIPLARPLVDAEGRFAGVAVASYAISDFIDFYKQLRTEDDMLIALVGRDGIVRARAARATSFGEDVSASR
AFRQTIANGAVVYDEVSVFDGVARVGYAVASTKYPILVTVAHSLAAVEQRSKEFRAAIWSTAIGLSVALFIVALLAGRYL
KLQKKLKANEVQALARQREANVLEAISRVPGVAVMHVTEAGASEVGTAADPTLSPLVRRYLASGRFRNLVRGLKEPQLRD
EHLSDGTSELEVEMVVAPLQDIDRAASPGQGGDMVVFAVDRTQRRMEENKLYQMSKLASLGEVATGLAHEINQPLGVIRL
AASNALTGLKVGLPPDHLAGKLDRIIQQTVRMSRIIDHMRIFGRKSEEQLQPSQPTQAVEGALQVVGAHFRLDEIEVNTM
SEPHLPDVLCRQDQLEQVIINLLQNARDAINERRAALGEHFAGRIAVRVAGEARIGAPEQVLIEVADNGGGIPEEVVERI
FQPFFTTKPPGKGTGLGLSVSFGIIRDHGGSLSVRNGSEGAIFSIRLPARLAAPALIGASAEIVQG

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=261, Percent_Identity=30.2681992337165, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=28.8135593220339, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75962; Mature: 75831

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARMKGPEALGDGLRGLVNPVTLMLVGLVVLVGVIPFVAALALYQMHDRAERDEAVADA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRTATLLLRSFEQSIAPVDLLLLNIASTYDASASPVQVHTMLRSINLPPAVLQVTITDKA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCC
GMLIASSLPTDGMEQKDLSGREYMRAYLGREAVHAGLSIGKPVLGLLSKKWGIPLARPLV
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCCCHHHHCC
DAEGRFAGVAVASYAISDFIDFYKQLRTEDDMLIALVGRDGIVRARAARATSFGEDVSAS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHH
RAFRQTIANGAVVYDEVSVFDGVARVGYAVASTKYPILVTVAHSLAAVEQRSKEFRAAIW
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
STAIGLSVALFIVALLAGRYLKLQKKLKANEVQALARQREANVLEAISRVPGVAVMHVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
AGASEVGTAADPTLSPLVRRYLASGRFRNLVRGLKEPQLRDEHLSDGTSELEVEMVVAPL
CCCHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHCCCCCCEEEHHHHHCH
QDIDRAASPGQGGDMVVFAVDRTQRRMEENKLYQMSKLASLGEVATGLAHEINQPLGVIR
HHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEE
LAASNALTGLKVGLPPDHLAGKLDRIIQQTVRMSRIIDHMRIFGRKSEEQLQPSQPTQAV
EHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHH
EGALQVVGAHFRLDEIEVNTMSEPHLPDVLCRQDQLEQVIINLLQNARDAINERRAALGE
HHHHHHHHHHEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFAGRIAVRVAGEARIGAPEQVLIEVADNGGGIPEEVVERIFQPFFTTKPPGKGTGLGLS
HHHCEEEEEEECCCCCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
VSFGIIRDHGGSLSVRNGSEGAIFSIRLPARLAAPALIGASAEIVQG
EEEEEEECCCCEEEECCCCCCCEEEEECCHHHHCHHHHCCCHHHCCC
>Mature Secondary Structure 
AARMKGPEALGDGLRGLVNPVTLMLVGLVVLVGVIPFVAALALYQMHDRAERDEAVADA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRTATLLLRSFEQSIAPVDLLLLNIASTYDASASPVQVHTMLRSINLPPAVLQVTITDKA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCC
GMLIASSLPTDGMEQKDLSGREYMRAYLGREAVHAGLSIGKPVLGLLSKKWGIPLARPLV
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCCCHHHHCC
DAEGRFAGVAVASYAISDFIDFYKQLRTEDDMLIALVGRDGIVRARAARATSFGEDVSAS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHH
RAFRQTIANGAVVYDEVSVFDGVARVGYAVASTKYPILVTVAHSLAAVEQRSKEFRAAIW
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
STAIGLSVALFIVALLAGRYLKLQKKLKANEVQALARQREANVLEAISRVPGVAVMHVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
AGASEVGTAADPTLSPLVRRYLASGRFRNLVRGLKEPQLRDEHLSDGTSELEVEMVVAPL
CCCHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHCCCCCCEEEHHHHHCH
QDIDRAASPGQGGDMVVFAVDRTQRRMEENKLYQMSKLASLGEVATGLAHEINQPLGVIR
HHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEE
LAASNALTGLKVGLPPDHLAGKLDRIIQQTVRMSRIIDHMRIFGRKSEEQLQPSQPTQAV
EHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHH
EGALQVVGAHFRLDEIEVNTMSEPHLPDVLCRQDQLEQVIINLLQNARDAINERRAALGE
HHHHHHHHHHEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFAGRIAVRVAGEARIGAPEQVLIEVADNGGGIPEEVVERIFQPFFTTKPPGKGTGLGLS
HHHCEEEEEEECCCCCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
VSFGIIRDHGGSLSVRNGSEGAIFSIRLPARLAAPALIGASAEIVQG
EEEEEEECCCCEEEECCCCCCCEEEEECCHHHHCHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]