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The map label for this gene is dctD [H]

Identifier: 154245062

GI number: 154245062

Start: 1283957

End: 1284757

Strand: Reverse

Name: dctD [H]

Synonym: Xaut_1114

Alternate gene names: 154245062

Gene position: 1284757-1283957 (Counterclockwise)

Preceding gene: 154245065

Following gene: 154245060

Centisome position: 24.2

GC content: 69.79

Gene sequence:

>801_bases
ATGGACGGGCGGACCGAAACAGCCCCGCGTGTTCTGCTGGTGGACGATGATCCCGACGTGCTCATCGAGTTGCAGGAGGG
CCTCGGCATGCTGGGCATCGCCGCCCTGACCGCCGGCACCGCGGTCGAGGCGCTCGACCTGGTCCGGCTCAATGACGACC
TGCAGGTCATCGTCACCGACCTGGAAATGCCACGCATCGACGGCATCGAACTGCTGCAGAAGCTCTCGACACGGCGGCGC
AAGCATCCCATGGCCGCCATCGTCATCACCGGCCACGCCTCCCTCGACCGTGCCGTCGGGGCGTTGCGGCTGCATGCGGT
GGACTTTCTGCAGAAGCCGCTGGCCGCGGAGGAGGTTGCCCACGCCATCACCCGCGCCTTCGCGCTGGTGGAGGACGAGG
CCGGCTCCGGAGACGAAGCGGCGGCGACGGGCCACATCGCCCGCCCCGTTTCCCCGCGCGCCCAATATCTCCGCGTATTG
GTCGCCGCCCGCGCCGACCGCGACTCGCTCTTCCAGGCGGGCCTGTTTTCCGACCCCGCCTGGGAGATGATGCTTGATCT
GGCGGTAGCGGAAGCGAGCCAGCGGCCCATCTCGGTCACCAGCCTGTGCATCGCCTCCGGCGCGCCCACCACCACCGCCC
TGCGCCGCATCGACGACCTGGAGGCGGCGGGGCTCGTGACCCGCGTTCCCGACGCTTGCGACCGGCGGCGCATCATCGTC
CACCTCACCGATCTGGGGCGCGAGCGCATGGAGGCCTTCGTGCGCCGGCAGGCCGAGCGCTTCGGCATAAGGCTGGATTG
A

Upstream 100 bases:

>100_bases
ACTTCAACCAGAAGCCGAAAGAACAGGCGCCGCGATAGCGGCCTGCTTGCCCTTCAGGCTGGACTCGGCCATCGCCGTAC
GGGGATCGCTGGAGGAGAAG

Downstream 100 bases:

>100_bases
GACCTGGCATCGTCGGCCCGCGCCTGCGGACCATCGGATATGGGAGCGCCTCGCTCCGAGAGCCGGAACGGGCCGGATGG
CACCGCATGCGGCCACCACC

Product: response regulator receiver protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MDGRTETAPRVLLVDDDPDVLIELQEGLGMLGIAALTAGTAVEALDLVRLNDDLQVIVTDLEMPRIDGIELLQKLSTRRR
KHPMAAIVITGHASLDRAVGALRLHAVDFLQKPLAAEEVAHAITRAFALVEDEAGSGDEAAATGHIARPVSPRAQYLRVL
VAARADRDSLFQAGLFSDPAWEMMLDLAVAEASQRPISVTSLCIASGAPTTTALRRIDDLEAAGLVTRVPDACDRRRIIV
HLTDLGRERMEAFVRRQAERFGIRLD

Sequences:

>Translated_266_residues
MDGRTETAPRVLLVDDDPDVLIELQEGLGMLGIAALTAGTAVEALDLVRLNDDLQVIVTDLEMPRIDGIELLQKLSTRRR
KHPMAAIVITGHASLDRAVGALRLHAVDFLQKPLAAEEVAHAITRAFALVEDEAGSGDEAAATGHIARPVSPRAQYLRVL
VAARADRDSLFQAGLFSDPAWEMMLDLAVAEASQRPISVTSLCIASGAPTTTALRRIDDLEAAGLVTRVPDACDRRRIIV
HLTDLGRERMEAFVRRQAERFGIRLD
>Mature_266_residues
MDGRTETAPRVLLVDDDPDVLIELQEGLGMLGIAALTAGTAVEALDLVRLNDDLQVIVTDLEMPRIDGIELLQKLSTRRR
KHPMAAIVITGHASLDRAVGALRLHAVDFLQKPLAAEEVAHAITRAFALVEDEAGSGDEAAATGHIARPVSPRAQYLRVL
VAARADRDSLFQAGLFSDPAWEMMLDLAVAEASQRPISVTSLCIASGAPTTTALRRIDDLEAAGLVTRVPDACDRRRIIV
HLTDLGRERMEAFVRRQAERFGIRLD

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=30.6451612903226, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 28891; Mature: 28891

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01117 HTH_MARR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRTETAPRVLLVDDDPDVLIELQEGLGMLGIAALTAGTAVEALDLVRLNDDLQVIVTD
CCCCCCCCCEEEEEECCCCCEEEEHHCCCHHHHHHHHHCHHHHHHHHEEECCCEEEEEEE
LEMPRIDGIELLQKLSTRRRKHPMAAIVITGHASLDRAVGALRLHAVDFLQKPLAAEEVA
CCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
HAITRAFALVEDEAGSGDEAAATGHIARPVSPRAQYLRVLVAARADRDSLFQAGLFSDPA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCHH
WEMMLDLAVAEASQRPISVTSLCIASGAPTTTALRRIDDLEAAGLVTRVPDACDRRRIIV
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCEEEE
HLTDLGRERMEAFVRRQAERFGIRLD
EEHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDGRTETAPRVLLVDDDPDVLIELQEGLGMLGIAALTAGTAVEALDLVRLNDDLQVIVTD
CCCCCCCCCEEEEEECCCCCEEEEHHCCCHHHHHHHHHCHHHHHHHHEEECCCEEEEEEE
LEMPRIDGIELLQKLSTRRRKHPMAAIVITGHASLDRAVGALRLHAVDFLQKPLAAEEVA
CCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
HAITRAFALVEDEAGSGDEAAATGHIARPVSPRAQYLRVLVAARADRDSLFQAGLFSDPA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCHH
WEMMLDLAVAEASQRPISVTSLCIASGAPTTTALRRIDDLEAAGLVTRVPDACDRRRIIV
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCEEEE
HLTDLGRERMEAFVRRQAERFGIRLD
EEHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]