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The map label for this gene is sfp [H]

Identifier: 154244964

GI number: 154244964

Start: 1164582

End: 1165379

Strand: Direct

Name: sfp [H]

Synonym: Xaut_1014

Alternate gene names: 154244964

Gene position: 1164582-1165379 (Clockwise)

Preceding gene: 154244963

Following gene: 154244966

Centisome position: 21.94

GC content: 72.43

Gene sequence:

>798_bases
ATGCGGCTTGAGGACGGCGTGTCCGCCCACGGGGCTGCACCCGGCGAGGTGCTGGTCCTGCACGGCTTCACCCACGTGCT
GGCGCAGGAGGACGTGCGCCGGCACGTGATGGCCTGCCTCAGCCCCGAGGAGGAGGCCCGCCGCCGGGCCTTCGCTTTTC
CCCGCGACCGCGACATGTTTCTTCTGGCCCATGGGGTGATGCGGCTGGCGCTCGGCCGCGTCATGGGGGTCGGTCCGCGG
GACCTCGCCTTCACCCGCGATGCCTATGGCAAGCCGTTCCTCGCCGGACCGTTCGAGGCGGGGCCGGGGTTCAGCCTGTC
CCATTCGGGGCAGGCCATCGCCATTGCCATCGCCCGCGCGCCGCTGGTGGGCGTCGATGTGGAGGCCCACGGCCGCGAGG
TTCCGCTGGAGGCCATGGCCATGGTCATGGCCGATGCCGAGGTGGCAGACCTTGCCGCTTCCGGTGGTTCCGCCCGGCGC
AAGGCGTTTGCCTACTGGACCCTGCGCGAGGCCTTCGCCAAGGCCGTGGGCCTGGGCCTGTCGCTGCCGCGCAATGCCGT
CTCCTTCCGCCTCGGGGGACAAGGTCCCGCCGGCGAGGGGGCTCCGGCCGTCGCCCATCTCTCCGAGCAGTTCGGGACGG
CCGGCGACTGGCACCTCCACCAATGCGACCTTGGCCCGGACCATATTCTGGCCGTCGCCGCGCGGGTCCCGGGACCGGTG
GCGTGGCGGCTGCTGCCCATCGAGAGCGTTCTCCCTTGCGCGGGTAGCGTCAGAGCGCCGGCCCGGCCCGTTCCCTGA

Upstream 100 bases:

>100_bases
ACGCGCCCCTGCTGTGGGACGCGCCCGCCCAGCAGGCGATCATCGCCTTCATCCGCTCGGTGTCGTAATCCGCGCAGGGG
CGCGGAGAGGGGGGATCGCG

Downstream 100 bases:

>100_bases
ACTGGGCGGCCATCCAGTCGATGAGCACGCGCAGCCGCGGCGAGAGCTGGCGGGTGTGCGAATACAGCACATGGACCGGC
AGGGCGGCGGGCGGGAAGTC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Surfactin synthase-activating enzyme [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRLEDGVSAHGAAPGEVLVLHGFTHVLAQEDVRRHVMACLSPEEEARRRAFAFPRDRDMFLLAHGVMRLALGRVMGVGPR
DLAFTRDAYGKPFLAGPFEAGPGFSLSHSGQAIAIAIARAPLVGVDVEAHGREVPLEAMAMVMADAEVADLAASGGSARR
KAFAYWTLREAFAKAVGLGLSLPRNAVSFRLGGQGPAGEGAPAVAHLSEQFGTAGDWHLHQCDLGPDHILAVAARVPGPV
AWRLLPIESVLPCAGSVRAPARPVP

Sequences:

>Translated_265_residues
MRLEDGVSAHGAAPGEVLVLHGFTHVLAQEDVRRHVMACLSPEEEARRRAFAFPRDRDMFLLAHGVMRLALGRVMGVGPR
DLAFTRDAYGKPFLAGPFEAGPGFSLSHSGQAIAIAIARAPLVGVDVEAHGREVPLEAMAMVMADAEVADLAASGGSARR
KAFAYWTLREAFAKAVGLGLSLPRNAVSFRLGGQGPAGEGAPAVAHLSEQFGTAGDWHLHQCDLGPDHILAVAARVPGPV
AWRLLPIESVLPCAGSVRAPARPVP
>Mature_265_residues
MRLEDGVSAHGAAPGEVLVLHGFTHVLAQEDVRRHVMACLSPEEEARRRAFAFPRDRDMFLLAHGVMRLALGRVMGVGPR
DLAFTRDAYGKPFLAGPFEAGPGFSLSHSGQAIAIAIARAPLVGVDVEAHGREVPLEAMAMVMADAEVADLAASGGSARR
KAFAYWTLREAFAKAVGLGLSLPRNAVSFRLGGQGPAGEGAPAVAHLSEQFGTAGDWHLHQCDLGPDHILAVAARVPGPV
AWRLLPIESVLPCAGSVRAPARPVP

Specific function: Activates the seven peptidyl carrier protein (PCP) domains of surfactin synthase SRF1/2/3 by transferring the 4'- phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for cells of B.subtilis to become producers of the lipopeptide a

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR004568 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27902; Mature: 27902

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLEDGVSAHGAAPGEVLVLHGFTHVLAQEDVRRHVMACLSPEEEARRRAFAFPRDRDMF
CCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHH
LLAHGVMRLALGRVMGVGPRDLAFTRDAYGKPFLAGPFEAGPGFSLSHSGQAIAIAIARA
HHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
PLVGVDVEAHGREVPLEAMAMVMADAEVADLAASGGSARRKAFAYWTLREAFAKAVGLGL
CEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
SLPRNAVSFRLGGQGPAGEGAPAVAHLSEQFGTAGDWHLHQCDLGPDHILAVAARVPGPV
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHEEHHHCCCCE
AWRLLPIESVLPCAGSVRAPARPVP
EEEEEEHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLEDGVSAHGAAPGEVLVLHGFTHVLAQEDVRRHVMACLSPEEEARRRAFAFPRDRDMF
CCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHH
LLAHGVMRLALGRVMGVGPRDLAFTRDAYGKPFLAGPFEAGPGFSLSHSGQAIAIAIARA
HHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
PLVGVDVEAHGREVPLEAMAMVMADAEVADLAASGGSARRKAFAYWTLREAFAKAVGLGL
CEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
SLPRNAVSFRLGGQGPAGEGAPAVAHLSEQFGTAGDWHLHQCDLGPDHILAVAARVPGPV
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHEEHHHCCCCE
AWRLLPIESVLPCAGSVRAPARPVP
EEEEEEHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1557038; 8407792; 8355609; 8639027; 9384377; 8939709; 9484229; 10581256 [H]