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The map label for this gene is yusP [H]

Identifier: 154244950

GI number: 154244950

Start: 1119130

End: 1120725

Strand: Reverse

Name: yusP [H]

Synonym: Xaut_1000

Alternate gene names: 154244950

Gene position: 1120725-1119130 (Counterclockwise)

Preceding gene: 154244951

Following gene: 154244948

Centisome position: 21.11

GC content: 71.24

Gene sequence:

>1596_bases
GTGAGCGCACCCGCTCCCCTCCCGGCCGCGAGCGAAGACGCCGCCATCGCGCTACCGCCGGACAAATTCCATCGCGTGCT
GGCCGGGCTGCTGCTGGTGCTGGCGCTGAGCTCGCTCGACGCCAACATCGTCGGCCCGGCCCTGCCGCTGATCTCCAGCG
AGTTCGGCGCCCTCGACAGCCTGACCTGGGTGCTGACCATCTTCCTCCTCACCAGCACCGCCGCAACGCCGCTCTACGGC
AAGCTCAGCGACATGTATGGCCGCCGGCCGCTGCTCACCATCGCGGTGCTGCTGTTCCTCGCCGGCTCGGCCTTCAGCGG
CCTCGCCCAGAGCATGAACCAGCTCATCCTCGGCCGCGCCATCCAGGGCGTCGGCGCCGGCGGGCTGATGACGCTCACCC
AGATCACCATGTCGGACCTGGTGTCGCCGCGGCGGCGCGGCAGCTACCAGGGGCTGTTCGGCGCGGTGTTCACCATCGCC
AGCCTCGCCGGGCCGCCGCTGGGCGGCGTCATCGCCGAATTCTGGTCGTGGCGGTGGATCTTCTACGTGAACCTGCCGCT
GGGCGCCGCCGCACTCACCCTGCTGTGGATGGGCCTGCCGCCGGGCGTGCGCACCACCAGCCACCGCATCGATGTTCTCG
GCTTCGTCGTCATCATGGCCGCCACCAGCTGCGTGCTGATGGCGCTGAACCAGGGCAGCCACGGCAGCTGGACCTCCCCC
ATCGTCATCAGCCTCGCCGTCGCCGCCGTGGTGCTGGCGCTGCTGCTGGGGCCGATCGAAGCGCGGGCGAAAGAGCCCCT
CATTCCGCTCGCCATGGTGGGCAACTCCGTCTGGCTGATCGCCACCGGGGTCGCGACGCTCGTCACCATCGCGGTGTTCG
GCGCCCTCGCCTTCATGCCGCTCTACCTGCAACTCGCCGGCGGGCTCTCGCCCACCGCCTCCGGCATCGCCATGGTGCCC
TCCGCGGCCGGGCTGATGCTGTCGCTGCTGTATGGCGGGCGGGCCATCACCCGCACCGGGCGCTACAAGGTGTTCGCGGT
CACCGGCGTCGGCGTCGCGACGCTCGCCCTGTTCGCGCTGGCGCTTGCGGCCTATGCCCTGCCCTCCCCCTACCTCCTGG
GCGCGCTGCTGTTTCCCCTCGGCGCCGGGCTGGGCCTGCTGATGCCCGGCCTGACGGTGGCCTACCAGAACGCGGTGGCC
CACGAGGACATCGGCACCGCCACGTCCACGGCGGGCTTCTTCCGGTCCCTCGGCGGCGCCTTCGGCATCGCGGTGGCCGG
CGCCATCCTCGCCATGCAGGCGGGCGGGCTGCTGCCGGCCGGCGGCGGCGCGCAGGACATGGACAATATCGGGCTCGGGC
AATTGTCCCAGCTGAGCCCGTCGGCGCAAGCGATGGTGCTTGCCGACTACCAGTGGGCCATGGTCACCATCTTCGCCGCC
GCCGGCGTGGTGGCGGCGCTGGCGTTCGCGCTCATCCGGCTGCTGCCGGAGCAGGAATTGTCCGACGTGGCCAACCGGCC
CGCGTCCAACGCGCTTGAGTCCAACCCGCTTGGGTCCGATCCGCCTGGGGCAAACCCGCCCGGCACCAAGTCATGA

Upstream 100 bases:

>100_bases
TGATCGATGTTCCACAGGATGTGGCGGACCTGCTCCTCGCCTGCGCCGAGGCGGCACGTACTGTCGAAGCGACATGCGCC
GCGCCCACAGGATCCCCCTC

Downstream 100 bases:

>100_bases
CCCGGACGCGCCGGTTCCCGGCGGCGCCGTTTCAATCGGCGCCTGAGCCGCAATCCAGCCGATCTCCTCCAGTTGCGCGA
TGGCGGCGCCGATATCGGCC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSAPAPLPAASEDAAIALPPDKFHRVLAGLLLVLALSSLDANIVGPALPLISSEFGALDSLTWVLTIFLLTSTAATPLYG
KLSDMYGRRPLLTIAVLLFLAGSAFSGLAQSMNQLILGRAIQGVGAGGLMTLTQITMSDLVSPRRRGSYQGLFGAVFTIA
SLAGPPLGGVIAEFWSWRWIFYVNLPLGAAALTLLWMGLPPGVRTTSHRIDVLGFVVIMAATSCVLMALNQGSHGSWTSP
IVISLAVAAVVLALLLGPIEARAKEPLIPLAMVGNSVWLIATGVATLVTIAVFGALAFMPLYLQLAGGLSPTASGIAMVP
SAAGLMLSLLYGGRAITRTGRYKVFAVTGVGVATLALFALALAAYALPSPYLLGALLFPLGAGLGLLMPGLTVAYQNAVA
HEDIGTATSTAGFFRSLGGAFGIAVAGAILAMQAGGLLPAGGGAQDMDNIGLGQLSQLSPSAQAMVLADYQWAMVTIFAA
AGVVAALAFALIRLLPEQELSDVANRPASNALESNPLGSDPPGANPPGTKS

Sequences:

>Translated_531_residues
MSAPAPLPAASEDAAIALPPDKFHRVLAGLLLVLALSSLDANIVGPALPLISSEFGALDSLTWVLTIFLLTSTAATPLYG
KLSDMYGRRPLLTIAVLLFLAGSAFSGLAQSMNQLILGRAIQGVGAGGLMTLTQITMSDLVSPRRRGSYQGLFGAVFTIA
SLAGPPLGGVIAEFWSWRWIFYVNLPLGAAALTLLWMGLPPGVRTTSHRIDVLGFVVIMAATSCVLMALNQGSHGSWTSP
IVISLAVAAVVLALLLGPIEARAKEPLIPLAMVGNSVWLIATGVATLVTIAVFGALAFMPLYLQLAGGLSPTASGIAMVP
SAAGLMLSLLYGGRAITRTGRYKVFAVTGVGVATLALFALALAAYALPSPYLLGALLFPLGAGLGLLMPGLTVAYQNAVA
HEDIGTATSTAGFFRSLGGAFGIAVAGAILAMQAGGLLPAGGGAQDMDNIGLGQLSQLSPSAQAMVLADYQWAMVTIFAA
AGVVAALAFALIRLLPEQELSDVANRPASNALESNPLGSDPPGANPPGTKS
>Mature_530_residues
SAPAPLPAASEDAAIALPPDKFHRVLAGLLLVLALSSLDANIVGPALPLISSEFGALDSLTWVLTIFLLTSTAATPLYGK
LSDMYGRRPLLTIAVLLFLAGSAFSGLAQSMNQLILGRAIQGVGAGGLMTLTQITMSDLVSPRRRGSYQGLFGAVFTIAS
LAGPPLGGVIAEFWSWRWIFYVNLPLGAAALTLLWMGLPPGVRTTSHRIDVLGFVVIMAATSCVLMALNQGSHGSWTSPI
VISLAVAAVVLALLLGPIEARAKEPLIPLAMVGNSVWLIATGVATLVTIAVFGALAFMPLYLQLAGGLSPTASGIAMVPS
AAGLMLSLLYGGRAITRTGRYKVFAVTGVGVATLALFALALAAYALPSPYLLGALLFPLGAGLGLLMPGLTVAYQNAVAH
EDIGTATSTAGFFRSLGGAFGIAVAGAILAMQAGGLLPAGGGAQDMDNIGLGQLSQLSPSAQAMVLADYQWAMVTIFAAA
GVVAALAFALIRLLPEQELSDVANRPASNALESNPLGSDPPGANPPGTKS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=439, Percent_Identity=26.1958997722096, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788710, Length=401, Percent_Identity=26.9326683291771, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790195, Length=442, Percent_Identity=27.3755656108597, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081983, Length=416, Percent_Identity=25.9615384615385, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788392, Length=357, Percent_Identity=31.0924369747899, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790146, Length=157, Percent_Identity=29.2993630573248, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=319, Percent_Identity=31.3479623824451, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319770, Length=408, Percent_Identity=28.6764705882353, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322958, Length=457, Percent_Identity=25.8205689277899, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321663, Length=172, Percent_Identity=34.8837209302326, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=250, Percent_Identity=27.2, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321747, Length=432, Percent_Identity=24.537037037037, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324954, Length=415, Percent_Identity=23.1325301204819, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319783, Length=369, Percent_Identity=24.1192411924119, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54147; Mature: 54016

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPAPLPAASEDAAIALPPDKFHRVLAGLLLVLALSSLDANIVGPALPLISSEFGALDS
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCHHHH
LTWVLTIFLLTSTAATPLYGKLSDMYGRRPLLTIAVLLFLAGSAFSGLAQSMNQLILGRA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IQGVGAGGLMTLTQITMSDLVSPRRRGSYQGLFGAVFTIASLAGPPLGGVIAEFWSWRWI
HHCCCCCHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEE
FYVNLPLGAAALTLLWMGLPPGVRTTSHRIDVLGFVVIMAATSCVLMALNQGSHGSWTSP
EEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
IVISLAVAAVVLALLLGPIEARAKEPLIPLAMVGNSVWLIATGVATLVTIAVFGALAFMP
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
LYLQLAGGLSPTASGIAMVPSAAGLMLSLLYGGRAITRTGRYKVFAVTGVGVATLALFAL
HHHHHHCCCCCCCCCCEECCHHHHHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHH
ALAAYALPSPYLLGALLFPLGAGLGLLMPGLTVAYQNAVAHEDIGTATSTAGFFRSLGGA
HHHHHHCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FGIAVAGAILAMQAGGLLPAGGGAQDMDNIGLGQLSQLSPSAQAMVLADYQWAMVTIFAA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEECCHHHHHHHHHH
AGVVAALAFALIRLLPEQELSDVANRPASNALESNPLGSDPPGANPPGTKS
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPAPLPAASEDAAIALPPDKFHRVLAGLLLVLALSSLDANIVGPALPLISSEFGALDS
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHCHHHH
LTWVLTIFLLTSTAATPLYGKLSDMYGRRPLLTIAVLLFLAGSAFSGLAQSMNQLILGRA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IQGVGAGGLMTLTQITMSDLVSPRRRGSYQGLFGAVFTIASLAGPPLGGVIAEFWSWRWI
HHCCCCCHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEE
FYVNLPLGAAALTLLWMGLPPGVRTTSHRIDVLGFVVIMAATSCVLMALNQGSHGSWTSP
EEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
IVISLAVAAVVLALLLGPIEARAKEPLIPLAMVGNSVWLIATGVATLVTIAVFGALAFMP
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
LYLQLAGGLSPTASGIAMVPSAAGLMLSLLYGGRAITRTGRYKVFAVTGVGVATLALFAL
HHHHHHCCCCCCCCCCEECCHHHHHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHH
ALAAYALPSPYLLGALLFPLGAGLGLLMPGLTVAYQNAVAHEDIGTATSTAGFFRSLGGA
HHHHHHCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FGIAVAGAILAMQAGGLLPAGGGAQDMDNIGLGQLSQLSPSAQAMVLADYQWAMVTIFAA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEECCHHHHHHHHHH
AGVVAALAFALIRLLPEQELSDVANRPASNALESNPLGSDPPGANPPGTKS
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]