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The map label for this gene is mhpF [C]

Identifier: 154244887

GI number: 154244887

Start: 1056687

End: 1057634

Strand: Direct

Name: mhpF [C]

Synonym: Xaut_0937

Alternate gene names: 154244887

Gene position: 1056687-1057634 (Clockwise)

Preceding gene: 154244886

Following gene: 154244888

Centisome position: 19.9

GC content: 66.67

Gene sequence:

>948_bases
ATGAGCACGCCCAGGATCAAAGCCGCCATCATCGGCTCGGGCAACATCGGCACCGACCTGATGATCAAGATCATGCGCAC
GTCGCGGCACCTGGAGATGGGGGCCATGGTGGGCATCGATCCCAAGTCGGACGGCCTCGCCCGCGCCGCGCGCCTCAACG
TGCCGGTGACCCACGAGGGCATCGAGGGGCTGCGCCGCCTGCCCAATTACGCCGAGATCGGCGTGGTGTTCGACGCCACC
TCCGCCAAGGCCCACCTCACCAACAATGCGCTGCTCCAGAAGGACGGCAAGAAGGTGATCGACCTGACCCCCGCGGCGGT
CGGCCCCTTCACCATCCCGGCCATCAATGGCGATGCCAATCTCGAAGAGCCCAACGTGAACATGGTCACGTGCGGCGGCC
AGGCCACCATCCCGATGGTCTATGCCGTGAAGCGGGCGGTGAAGCGCCTGGTCTACGGGGAGATCGTCGCCTCCATCTCC
TCGAAGTCCGCCGGCCCGGGGACGCGCGCGAACATCGACGAATTCACCGAGACCACCTCGAAGGCCATCGAGGTGCTGGG
CGGGGCCGAGCGCGGCAAGGCGGTGATCATCCTCAATCCCGCCGAGCCGCCCCTGATCATGCGCGACACGGTCTTCACCC
TCAGCCAGGGCGGCGATCGGGAGGCCATCGAGGCCTCCATCCTTGAGATGGCCGAGACGGTGAAGACATACGTTCCCGGC
TATCGGCTGAAGCAGAAGGTGCAGTTCGAGGTCATCGGCGACAACGCGCCGGTGCGCATCCCCGGCATCGGCACTGCTTC
GGGCCTCAAGACCACCATCCTGCTCGAGGTGGAGGGCGCCGCCCACTATCTGCCGGCCTATGCCGGCAACCTCGACATCA
TGACCTCTGCCGCGCTGGTGACCGCTGATCGCTGGGCCGCGCGCAGGCTTGCGAAGGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
TGGTTCCGGTCGCGCCGGGCGATGTTCTCGAAGCGCGGATCGCCGGTCTCGGCTCGGTCAAGGTCTCCATCGGGACCCTC
AGCACCTCGGAGAAGCAGGC

Downstream 100 bases:

>100_bases
TGGCCCGTCCCAACAAAGACAAGCTCTATATCCAGGACGTGACCCTGCGCGACGGCATGCACGCGCTCAGGCACCAGTAC
GACCTTGCGGCGACGCGAGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSTPRIKAAIIGSGNIGTDLMIKIMRTSRHLEMGAMVGIDPKSDGLARAARLNVPVTHEGIEGLRRLPNYAEIGVVFDAT
SAKAHLTNNALLQKDGKKVIDLTPAAVGPFTIPAINGDANLEEPNVNMVTCGGQATIPMVYAVKRAVKRLVYGEIVASIS
SKSAGPGTRANIDEFTETTSKAIEVLGGAERGKAVIILNPAEPPLIMRDTVFTLSQGGDREAIEASILEMAETVKTYVPG
YRLKQKVQFEVIGDNAPVRIPGIGTASGLKTTILLEVEGAAHYLPAYAGNLDIMTSAALVTADRWAARRLAKEAA

Sequences:

>Translated_315_residues
MSTPRIKAAIIGSGNIGTDLMIKIMRTSRHLEMGAMVGIDPKSDGLARAARLNVPVTHEGIEGLRRLPNYAEIGVVFDAT
SAKAHLTNNALLQKDGKKVIDLTPAAVGPFTIPAINGDANLEEPNVNMVTCGGQATIPMVYAVKRAVKRLVYGEIVASIS
SKSAGPGTRANIDEFTETTSKAIEVLGGAERGKAVIILNPAEPPLIMRDTVFTLSQGGDREAIEASILEMAETVKTYVPG
YRLKQKVQFEVIGDNAPVRIPGIGTASGLKTTILLEVEGAAHYLPAYAGNLDIMTSAALVTADRWAARRLAKEAA
>Mature_314_residues
STPRIKAAIIGSGNIGTDLMIKIMRTSRHLEMGAMVGIDPKSDGLARAARLNVPVTHEGIEGLRRLPNYAEIGVVFDATS
AKAHLTNNALLQKDGKKVIDLTPAAVGPFTIPAINGDANLEEPNVNMVTCGGQATIPMVYAVKRAVKRLVYGEIVASISS
KSAGPGTRANIDEFTETTSKAIEVLGGAERGKAVIILNPAEPPLIMRDTVFTLSQGGDREAIEASILEMAETVKTYVPGY
RLKQKVQFEVIGDNAPVRIPGIGTASGLKTTILLEVEGAAHYLPAYAGNLDIMTSAALVTADRWAARRLAKEAA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=310, Percent_Identity=67.741935483871, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_XANP2 (A7IDU5)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415845.1
- ProteinModelPortal:   A7IDU5
- SMR:   A7IDU5
- STRING:   A7IDU5
- GeneID:   5424884
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0937
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   HVKNDAF
- ProtClustDB:   PRK08300
- BioCyc:   XAUT78245:XAUT_0937-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 33338; Mature: 33207

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: BINDING 290-290

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPRIKAAIIGSGNIGTDLMIKIMRTSRHLEMGAMVGIDPKSDGLARAARLNVPVTHEG
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCEEEECCCCCCCHHHHEEECCCCCHHH
IEGLRRLPNYAEIGVVFDATSAKAHLTNNALLQKDGKKVIDLTPAAVGPFTIPAINGDAN
HHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
LEEPNVNMVTCGGQATIPMVYAVKRAVKRLVYGEIVASISSKSAGPGTRANIDEFTETTS
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
KAIEVLGGAERGKAVIILNPAEPPLIMRDTVFTLSQGGDREAIEASILEMAETVKTYVPG
HHHHHHCCCCCCCEEEEECCCCCCEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
YRLKQKVQFEVIGDNAPVRIPGIGTASGLKTTILLEVEGAAHYLPAYAGNLDIMTSAALV
HHCCEEEEEEEECCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCHHCCCEEEEHHHHHH
TADRWAARRLAKEAA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
STPRIKAAIIGSGNIGTDLMIKIMRTSRHLEMGAMVGIDPKSDGLARAARLNVPVTHEG
CCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCEEEECCCCCCCHHHHEEECCCCCHHH
IEGLRRLPNYAEIGVVFDATSAKAHLTNNALLQKDGKKVIDLTPAAVGPFTIPAINGDAN
HHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
LEEPNVNMVTCGGQATIPMVYAVKRAVKRLVYGEIVASISSKSAGPGTRANIDEFTETTS
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
KAIEVLGGAERGKAVIILNPAEPPLIMRDTVFTLSQGGDREAIEASILEMAETVKTYVPG
HHHHHHCCCCCCCEEEEECCCCCCEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
YRLKQKVQFEVIGDNAPVRIPGIGTASGLKTTILLEVEGAAHYLPAYAGNLDIMTSAALV
HHCCEEEEEEEECCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCHHCCCEEEEHHHHHH
TADRWAARRLAKEAA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA