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The map label for this gene is mdtA [H]

Identifier: 154244777

GI number: 154244777

Start: 922908

End: 924032

Strand: Direct

Name: mdtA [H]

Synonym: Xaut_0827

Alternate gene names: 154244777

Gene position: 922908-924032 (Clockwise)

Preceding gene: 154244776

Following gene: 154244778

Centisome position: 17.38

GC content: 72.44

Gene sequence:

>1125_bases
GTGGCCGACGTGATTGATCGCGCGCCCAACGCCGTTGTTTCCACAGTCGTTCGGCTGGGAGCGTCGGCGGTGCTCCTCGG
CGGCACCTTGCTGCTGGCGGGATGCGGCGAGGCACCGGAGGCGAAGGCGCCCGAGCCGCGTCCGGTGCGCACCGTTCTTG
CCACCAGCCGCGCGGCCAGCGATGCGGTGACCCTCACCGGCCAGGTGGAGGCGCAGAACGAGGCCACCTACGGCTTCCGC
ATCGGCGGGCGCATCATCGAGCGGCTGGTGAATGTGGGCGACCAGGTAAAGCCTGGGCAGGTGCTGGCGCGGCTCGATCC
CCAGGACGAGCAGAACGCCCTGCGCTCGGCCCAGGCGGCGCTTTCGGCGGCCAACGCCAATCTCAGCCAGACCCGCAACC
AGTATGAACGCCAGCGCCAGCTGCTGGCCCGTGGCTTCACCCCCCGCGCCCAGTATGAGCAGGCCGAGCAGGCCTTCCTC
AACGCCCGCTCCCAGGTGGAGGACACCGAGGCCCGCCTGCGGATGGCGCAGGACCGGCTCGGCTTCACCGAGCTGAAGGC
GGATTCCGCCGGCGTCGTCACCCAGCGGCGGGCCGAGCCCGGCGAGGTGGTGCAGGCCGGCCAGCCGGTGGTGGAGGTGG
CGCGCCGCGACGGCCGCGACGCCGTGTTCGAGGTGCCGGCCGCGCTCCTCACCTCCCTGCCCGGCGATCCCGAGGTGGAG
GTGGCCCTTTCGGGCGACCCCGCCGTCAAGGCCGCCGGCCGGGTGCGCGAGGTGGCGCCGCAGGCGGATCCGGTCACCCG
CACCTTCCGCGTGCGCGTCGGCCTCATCGATCCGCCGGAGGGGCTGCGGCTCGGCACCACGGTGACCGGCCGCGTGGTGG
TGGACAGCGGCCCGGTGATCGAGATCCCGGCCAGCGCGCTCACCCGATTCAATGACAAGCCGGCGGTGTGGGTGGTGGAC
CCGAAGGCGCAGACGGTCTCCCTGCGCAATGTGGAGGTGCTGCGCTTCAGTCCCGCCACCGTGAGTGTGGCCGAGGGGCT
CAAGCCCTCCGAGATCGTGGTGACGGCGGGCGTTCAGGCGCTCCATCCGGGGCAGAAGGTGCGCCTTCTGGGGACCCAGC
TGTGA

Upstream 100 bases:

>100_bases
TGATCACGCTCCGTCGAGCCGATCCCGCGCGCTCTGGCCGCGCCGGGCGACCTCCGCTATAGGGGTGCGCGGTTGCCGTT
CCCCAATGAGGAGTTGTCCT

Downstream 100 bases:

>100_bases
GCGGCGGGTTCAACCTCTCCGCCTGGGCGCTGAAGCACCGCTCGGTCATCATCTATCTCATGGCCATCTCGGTGGTGGCC
GGCATCATGGCCTTCCGGAA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MADVIDRAPNAVVSTVVRLGASAVLLGGTLLLAGCGEAPEAKAPEPRPVRTVLATSRAASDAVTLTGQVEAQNEATYGFR
IGGRIIERLVNVGDQVKPGQVLARLDPQDEQNALRSAQAALSAANANLSQTRNQYERQRQLLARGFTPRAQYEQAEQAFL
NARSQVEDTEARLRMAQDRLGFTELKADSAGVVTQRRAEPGEVVQAGQPVVEVARRDGRDAVFEVPAALLTSLPGDPEVE
VALSGDPAVKAAGRVREVAPQADPVTRTFRVRVGLIDPPEGLRLGTTVTGRVVVDSGPVIEIPASALTRFNDKPAVWVVD
PKAQTVSLRNVEVLRFSPATVSVAEGLKPSEIVVTAGVQALHPGQKVRLLGTQL

Sequences:

>Translated_374_residues
MADVIDRAPNAVVSTVVRLGASAVLLGGTLLLAGCGEAPEAKAPEPRPVRTVLATSRAASDAVTLTGQVEAQNEATYGFR
IGGRIIERLVNVGDQVKPGQVLARLDPQDEQNALRSAQAALSAANANLSQTRNQYERQRQLLARGFTPRAQYEQAEQAFL
NARSQVEDTEARLRMAQDRLGFTELKADSAGVVTQRRAEPGEVVQAGQPVVEVARRDGRDAVFEVPAALLTSLPGDPEVE
VALSGDPAVKAAGRVREVAPQADPVTRTFRVRVGLIDPPEGLRLGTTVTGRVVVDSGPVIEIPASALTRFNDKPAVWVVD
PKAQTVSLRNVEVLRFSPATVSVAEGLKPSEIVVTAGVQALHPGQKVRLLGTQL
>Mature_373_residues
ADVIDRAPNAVVSTVVRLGASAVLLGGTLLLAGCGEAPEAKAPEPRPVRTVLATSRAASDAVTLTGQVEAQNEATYGFRI
GGRIIERLVNVGDQVKPGQVLARLDPQDEQNALRSAQAALSAANANLSQTRNQYERQRQLLARGFTPRAQYEQAEQAFLN
ARSQVEDTEARLRMAQDRLGFTELKADSAGVVTQRRAEPGEVVQAGQPVVEVARRDGRDAVFEVPAALLTSLPGDPEVEV
ALSGDPAVKAAGRVREVAPQADPVTRTFRVRVGLIDPPEGLRLGTTVTGRVVVDSGPVIEIPASALTRFNDKPAVWVVDP
KAQTVSLRNVEVLRFSPATVSVAEGLKPSEIVVTAGVQALHPGQKVRLLGTQL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=336, Percent_Identity=26.4880952380952, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789929, Length=310, Percent_Identity=25.4838709677419, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081796, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39690; Mature: 39558

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVIDRAPNAVVSTVVRLGASAVLLGGTLLLAGCGEAPEAKAPEPRPVRTVLATSRAAS
CCCHHHCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC
DAVTLTGQVEAQNEATYGFRIGGRIIERLVNVGDQVKPGQVLARLDPQDEQNALRSAQAA
CEEEEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCHHEEECCCCHHHHHHHHHHHH
LSAANANLSQTRNQYERQRQLLARGFTPRAQYEQAEQAFLNARSQVEDTEARLRMAQDRL
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFTELKADSAGVVTQRRAEPGEVVQAGQPVVEVARRDGRDAVFEVPAALLTSLPGDPEVE
CHHHCCCCCCCCEECCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEE
VALSGDPAVKAAGRVREVAPQADPVTRTFRVRVGLIDPPEGLRLGTTVTGRVVVDSGPVI
EEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEECCEEEEEEEECCCCEE
EIPASALTRFNDKPAVWVVDPKAQTVSLRNVEVLRFSPATVSVAEGLKPSEIVVTAGVQA
EECHHHHHHCCCCCEEEEECCCCCEEEECCEEEEEECCCEEHHHCCCCCCEEEEECCCHH
LHPGQKVRLLGTQL
HCCCCEEEEEECCC
>Mature Secondary Structure 
ADVIDRAPNAVVSTVVRLGASAVLLGGTLLLAGCGEAPEAKAPEPRPVRTVLATSRAAS
CCHHHCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC
DAVTLTGQVEAQNEATYGFRIGGRIIERLVNVGDQVKPGQVLARLDPQDEQNALRSAQAA
CEEEEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCHHEEECCCCHHHHHHHHHHHH
LSAANANLSQTRNQYERQRQLLARGFTPRAQYEQAEQAFLNARSQVEDTEARLRMAQDRL
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFTELKADSAGVVTQRRAEPGEVVQAGQPVVEVARRDGRDAVFEVPAALLTSLPGDPEVE
CHHHCCCCCCCCEECCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEE
VALSGDPAVKAAGRVREVAPQADPVTRTFRVRVGLIDPPEGLRLGTTVTGRVVVDSGPVI
EEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEECCEEEEEEEECCCCEE
EIPASALTRFNDKPAVWVVDPKAQTVSLRNVEVLRFSPATVSVAEGLKPSEIVVTAGVQA
EECHHHHHHCCCCCEEEEECCCCCEEEECCEEEEEECCCEEHHHCCCCCCEEEEECCCHH
LHPGQKVRLLGTQL
HCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA