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The map label for this gene is accA

Identifier: 154244466

GI number: 154244466

Start: 564173

End: 565126

Strand: Direct

Name: accA

Synonym: Xaut_0509

Alternate gene names: 154244466

Gene position: 564173-565126 (Clockwise)

Preceding gene: 154244463

Following gene: 154244467

Centisome position: 10.63

GC content: 68.45

Gene sequence:

>954_bases
ATGCGCAGCTATCTGGACTTCGAGAAGCCGGTCGCCGAACTCGAGGCCAAGGTGGAAGAGCTGCGCGCGCTTGCCTCTGC
CGGCGATGGCGTGACCATCACCGACGAGGTGCAGCGGCTCGAGACCAAGGCCCGCGAGGCGCTCCTCGCCCTCTACGCCA
ATCTCACCCCCTGGCAGAAGACGCTGGTCGCGCGGCATCCGCAGCGGCCCCATTTCGCCGATTTCGCCAAGGGCCTGTTC
GAGGATTTCACCCCGCTCGCCGGTGACCGCAAGTTCGGCGAGGACGAGGCCATCATCGGCGGCTTCGCCCGCTTCCGCGG
CGAGGCGGTGTGCGTGTTGGGCCACGAGAAGGGCTCCACCACCGAAACCCGCATCCGGCACAATTTCGGCATGGCGCGCC
CCGAGGGCTACCGCAAGGCGGTCCGCATCATGGAGCTCGCCGACCGCTTCGGCATTCCCCTGATCTCGCTGGTGGACACC
GCCGGCGCCTATCCCGGCATCGGCGCCGAGGAGCGCGGCCAGGCCGAGGCCATCGCCCGCTCCACCGACGCCTGCCTCGC
CCTGGGCGCACCCAATGTGGCGCTGGTGATCGGCGAGGGCGGTTCGGGCGGGGCCATCGCCATCGCCACCGCCAACAAGG
TGCTGATGATGGAGCATGCCATCTACAGCGTGATCTCGCCGGAAGGTGCGGCCTCCATCCTGTGGCGCGATACTGCGAAG
GCGCAGGAAGCCGCCACCAACATGAAGATCACGGCGCAGGACCTGCTGAAGTTCGGTATCATCGATGCCATCGTGAAGGA
GCCGCCCGGCGGCGCCCATCGCGATCCGGAGGCCACCATCGGCGCCGCCGGGGATGCCATCGCTGATGCGCTGTCGCAGC
TCGCCGGCCTCGACGGGCCGGCCGTGCGCAAGGCGCGGCGTGACAAATTTCTCGCAATCGGCCGCTCGCTTTAA

Upstream 100 bases:

>100_bases
GCCTCGACTTGCCGACCTTGACTTGCCGACCCGGCGCAGGCAGCTTCCGGCCCCGTGGGCGGCGCCGGCAACGGGCCTCC
TCCAACCTTTACGGACCCTC

Downstream 100 bases:

>100_bases
CCATGAGCGCATGGCCGGCGGCCGCTGCCGGCCCGGCATCTCATCTTGGCCGCATTTGCCTTATTTTCTCGAAGCCTGTT
CAGGCGGTAGCACCAACGCT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQKTLVARHPQRPHFADFAKGLF
EDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGSTTETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDT
AGAYPGIGAEERGQAEAIARSTDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAK
AQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGPAVRKARRDKFLAIGRSL

Sequences:

>Translated_317_residues
MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQKTLVARHPQRPHFADFAKGLF
EDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGSTTETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDT
AGAYPGIGAEERGQAEAIARSTDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAK
AQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGPAVRKARRDKFLAIGRSL
>Mature_317_residues
MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQKTLVARHPQRPHFADFAKGLF
EDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGSTTETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDT
AGAYPGIGAEERGQAEAIARSTDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAK
AQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGPAVRKARRDKFLAIGRSL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=298, Percent_Identity=51.006711409396, Blast_Score=304, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_XANP2 (A7ICM4)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415424.1
- ProteinModelPortal:   A7ICM4
- SMR:   A7ICM4
- STRING:   A7ICM4
- GeneID:   5424328
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0509
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   XAUT78245:XAUT_0509-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 33744; Mature: 33744

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHH
TLVARHPQRPHFADFAKGLFEDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGST
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCC
TETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDTAGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAK
CCCCEEEECCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEECCHHH
AQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGP
HHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCH
AVRKARRDKFLAIGRSL
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHH
TLVARHPQRPHFADFAKGLFEDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGST
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCC
TETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDTAGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
STDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAK
CCCCEEEECCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEECCHHH
AQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGP
HHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCH
AVRKARRDKFLAIGRSL
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA