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The map label for this gene is sucC [H]

Identifier: 154244447

GI number: 154244447

Start: 543958

End: 545190

Strand: Direct

Name: sucC [H]

Synonym: Xaut_0490

Alternate gene names: 154244447

Gene position: 543958-545190 (Clockwise)

Preceding gene: 154244446

Following gene: 154244448

Centisome position: 10.25

GC content: 64.96

Gene sequence:

>1233_bases
ATGCGCGGCCCTCGTCGAGGGAGGAACCCCATGAACATTCACGAGTACCAGGCGAAAGCCCTTCTCAAGGAATTCGGCGT
GCCGGTGTCGCGCGGCCTTGCCGCCTTCACGCCACAGGACGCGGAAGCCGCCGCCGCGAAGCTGGGCGGCATCGCGTTCG
TGGTGAAGGCACAGATCCATGCGGGCGGGCGCGGCAAGGGCAAGTTCAAGGAACTGCCCGCAGAGGCCAAGGGCGGTGTG
CGGGTGGTGAAGACCGCCGCCGACGTGAAGGCGAATGCCGCGGAGATGCTCGGTAATACTCTGGTGACCATCCAGACCGG
GCCGGACGGCAAGCAGGTGAACCGCCTCTATATTGAGGAAGGCGCCTCCATCGACAAGGAATTCTACCTGTCCATGCTGG
TGGACCGCGCCACCGCGCGCGTCGCCTTCGTGGTCTCCACTGAGGGCGGCATGGACATCGAGGAGGTGGCCCATGCCACC
CCCGAGCGCATCGTCACCTTCTCCGTGGACCCGGCCACCGGCGTGCAGCCCCTGCACGGCCGCAAGGTGGCGCAGGCGCT
GGGCCTGTCCGGCGACCTCGCCAAGCAGGCGGTGGCGCTGACGGCAAACCTCTATCGCGCCTTCACCGATAAGGACATGA
GCCTTCTGGAGATCAACCCCCTGGTGCTGACGCGGGACGATCGCCTCGTCTGCCTCGACGCCAAGGTGGGGTTTGATTCC
AACGCCCTGTTCCGCCATCCGGAGGTGGTGCAACTGCGCGACGAGAGCGAGGAGGACTTCAAGGAGATCGAAGCCTCGCG
CTACGACCTGTCCTATATCGCCCTCGACGGCACCATCGGCTGCATGGTCAACGGCGCGGGCCTCGCCATGGCCACCATGG
ACATCATCAAACTCTACGGCCGCGAGCCGGCGAACTTCCTGGACGTGGGTGGCGGCGCCACCAAGGAGAAGGTGACGGCC
GCCTTCAAGATCATCACCGCCGATCCCAATGTCGAGGGAATCCTGGTGAACATCTTCGGCGGCATCATGCGCTGCGACGT
GATCGCGGAGGGCGTCATCGCCGCTGTGCGCCAGATGGGGCTGAACGTGCCCCTCGTGGTAAGGCTTGCCGGCACCAACG
TGGAAGAAGGCAAGAAGATCATCCGGGAATCGGGTCTGAACGTGATCCCGGCGGATGACCTCGATGACGCGGCGCAGAAG
ATTGTCGCGGCCGTGAAGAAGGAAGCTGCGTGA

Upstream 100 bases:

>100_bases
TCGCATTGGTGCGCGGCCCGGAATGCGTGCACACTCCGACTTTGGTCGCAAGGCCGAGGATGCAGGACGCAGCCGGAAGA
GCCGCGCCCGAGGTCGCCGC

Downstream 100 bases:

>100_bases
TGTCCGTGCTTATCGACGCCAATACCCGTGTCATCACCCAGGGCTTCACCGGCAAGAACGGCACCTTCCACGCCCAGCAG
GCCATTGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRGPRRGRNPMNIHEYQAKALLKEFGVPVSRGLAAFTPQDAEAAAAKLGGIAFVVKAQIHAGGRGKGKFKELPAEAKGGV
RVVKTAADVKANAAEMLGNTLVTIQTGPDGKQVNRLYIEEGASIDKEFYLSMLVDRATARVAFVVSTEGGMDIEEVAHAT
PERIVTFSVDPATGVQPLHGRKVAQALGLSGDLAKQAVALTANLYRAFTDKDMSLLEINPLVLTRDDRLVCLDAKVGFDS
NALFRHPEVVQLRDESEEDFKEIEASRYDLSYIALDGTIGCMVNGAGLAMATMDIIKLYGREPANFLDVGGGATKEKVTA
AFKIITADPNVEGILVNIFGGIMRCDVIAEGVIAAVRQMGLNVPLVVRLAGTNVEEGKKIIRESGLNVIPADDLDDAAQK
IVAAVKKEAA

Sequences:

>Translated_410_residues
MRGPRRGRNPMNIHEYQAKALLKEFGVPVSRGLAAFTPQDAEAAAAKLGGIAFVVKAQIHAGGRGKGKFKELPAEAKGGV
RVVKTAADVKANAAEMLGNTLVTIQTGPDGKQVNRLYIEEGASIDKEFYLSMLVDRATARVAFVVSTEGGMDIEEVAHAT
PERIVTFSVDPATGVQPLHGRKVAQALGLSGDLAKQAVALTANLYRAFTDKDMSLLEINPLVLTRDDRLVCLDAKVGFDS
NALFRHPEVVQLRDESEEDFKEIEASRYDLSYIALDGTIGCMVNGAGLAMATMDIIKLYGREPANFLDVGGGATKEKVTA
AFKIITADPNVEGILVNIFGGIMRCDVIAEGVIAAVRQMGLNVPLVVRLAGTNVEEGKKIIRESGLNVIPADDLDDAAQK
IVAAVKKEAA
>Mature_410_residues
MRGPRRGRNPMNIHEYQAKALLKEFGVPVSRGLAAFTPQDAEAAAAKLGGIAFVVKAQIHAGGRGKGKFKELPAEAKGGV
RVVKTAADVKANAAEMLGNTLVTIQTGPDGKQVNRLYIEEGASIDKEFYLSMLVDRATARVAFVVSTEGGMDIEEVAHAT
PERIVTFSVDPATGVQPLHGRKVAQALGLSGDLAKQAVALTANLYRAFTDKDMSLLEINPLVLTRDDRLVCLDAKVGFDS
NALFRHPEVVQLRDESEEDFKEIEASRYDLSYIALDGTIGCMVNGAGLAMATMDIIKLYGREPANFLDVGGGATKEKVTA
AFKIITADPNVEGILVNIFGGIMRCDVIAEGVIAAVRQMGLNVPLVVRLAGTNVEEGKKIIRESGLNVIPADDLDDAAQK
IVAAVKKEAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=395, Percent_Identity=45.0632911392405, Blast_Score=355, Evalue=5e-98,
Organism=Homo sapiens, GI157779135, Length=389, Percent_Identity=46.7866323907455, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI294862256, Length=369, Percent_Identity=46.3414634146341, Blast_Score=315, Evalue=4e-86,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=53.7878787878788, Blast_Score=415, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=47.3417721518987, Blast_Score=345, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI17539378, Length=407, Percent_Identity=45.2088452088452, Blast_Score=342, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6321683, Length=400, Percent_Identity=46, Blast_Score=369, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=50.6393861892583, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=50.6393861892583, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=50.761421319797, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=50.761421319797, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI21356231, Length=400, Percent_Identity=46, Blast_Score=333, Evalue=1e-91,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43696; Mature: 43696

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPRRGRNPMNIHEYQAKALLKEFGVPVSRGLAAFTPQDAEAAAAKLGGIAFVVKAQIH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEECCCCCHHHHHHHHCCEEEEEEEEEE
AGGRGKGKFKELPAEAKGGVRVVKTAADVKANAAEMLGNTLVTIQTGPDGKQVNRLYIEE
CCCCCCCCHHHCCCCCCCCEEEEEEHHHCCCCHHHHCCCEEEEEEECCCCCCEEEEEEEC
GASIDKEFYLSMLVDRATARVAFVVSTEGGMDIEEVAHATPERIVTFSVDPATGVQPLHG
CCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCC
RKVAQALGLSGDLAKQAVALTANLYRAFTDKDMSLLEINPLVLTRDDRLVCLDAKVGFDS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEEECCCCCC
NALFRHPEVVQLRDESEEDFKEIEASRYDLSYIALDGTIGCMVNGAGLAMATMDIIKLYG
CCEECCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHC
REPANFLDVGGGATKEKVTAAFKIITADPNVEGILVNIFGGIMRCDVIAEGVIAAVRQMG
CCCCCEEECCCCCCHHHEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
LNVPLVVRLAGTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA
CCCCEEEEEECCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGPRRGRNPMNIHEYQAKALLKEFGVPVSRGLAAFTPQDAEAAAAKLGGIAFVVKAQIH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEECCCCCHHHHHHHHCCEEEEEEEEEE
AGGRGKGKFKELPAEAKGGVRVVKTAADVKANAAEMLGNTLVTIQTGPDGKQVNRLYIEE
CCCCCCCCHHHCCCCCCCCEEEEEEHHHCCCCHHHHCCCEEEEEEECCCCCCEEEEEEEC
GASIDKEFYLSMLVDRATARVAFVVSTEGGMDIEEVAHATPERIVTFSVDPATGVQPLHG
CCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCC
RKVAQALGLSGDLAKQAVALTANLYRAFTDKDMSLLEINPLVLTRDDRLVCLDAKVGFDS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEEECCCCCC
NALFRHPEVVQLRDESEEDFKEIEASRYDLSYIALDGTIGCMVNGAGLAMATMDIIKLYG
CCEECCCCEEEECCCCHHHHHHHHHCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHC
REPANFLDVGGGATKEKVTAAFKIITADPNVEGILVNIFGGIMRCDVIAEGVIAAVRQMG
CCCCCEEECCCCCCHHHEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
LNVPLVVRLAGTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA
CCCCEEEEEECCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA