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The map label for this gene is gpmA

Identifier: 154244317

GI number: 154244317

Start: 373211

End: 373834

Strand: Direct

Name: gpmA

Synonym: Xaut_0360

Alternate gene names: 154244317

Gene position: 373211-373834 (Clockwise)

Preceding gene: 154244316

Following gene: 154244321

Centisome position: 7.03

GC content: 69.23

Gene sequence:

>624_bases
ATGTCCGACCGCATCCTCGTCCTCGTCCGTCACGGGCAGAGCGAGTGGAACCTGAAGAACCTGTTCACCGGGTGGCGCGA
CCCCGACCTCACCGAGCAGGGCGTCTCCGAGGCCAAGCGCGCCGGCGCGCTGCTGAAGGCCGAGGGGCTGAAGTTCGACG
TGGCCTTCACCTCCGATCTCACCCGCGCCCAGAAGACGCTGGGCCTCATCCTCGGCGAGATGGGCCAGGAGGGCGTGCCC
ACCACCCGCAACGTGGCCCTGAACGAGCGGGACTACGGCGACCTCGCCGGCCTGAACAAGGACGACGCCCGCGCCAAGTG
GGGTGACGACCAGGTGCACATCTGGCGCCGCTCCTACGACATCGCCCCGCCCGGCGGCGAGAGCCTGCGCGACACGGTGG
CCCGCACGCTGCCCTATTATGTGCAGGAAATCCTGCCGTGCGTGCTGCGCGGCCAGACGACGCTGGTGGCCGCCCACGGC
AACTCGCTGCGCGCCCTCATCATGACGCTGGAGAAGCTCTCCCCCGAGGGCATCATGAAGCGCGAGCTGAACACCGGCGC
GCCCATCGTCTACAAGCTGGCGGCGGATTCCACCGTGGCGGAGAAGCGCGACCTGGTGGCGTGA

Upstream 100 bases:

>100_bases
CGGCCTCGGCGATTTCTGAGCGCCGAATTCTGACCGCCGATTCCTTGTCCGCAGATTTTCGAGCCGGGAGCCACGCCCGG
AGACTACCCAGGAGCTTTCC

Downstream 100 bases:

>100_bases
CGCAAACGCTGAACGAAATGGCCGGTGAGCAATGCTCACCGGCCATTTCTATTTCACGCCTGTCAGTTCTGAACCCTACC
CCTGCTCGTGGAGCAGGCGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDRILVLVRHGQSEWNLKNLFTGWRDPDLTEQGVSEAKRAGALLKAEGLKFDVAFTSDLTRAQKTLGLILGEMGQEGVP
TTRNVALNERDYGDLAGLNKDDARAKWGDDQVHIWRRSYDIAPPGGESLRDTVARTLPYYVQEILPCVLRGQTTLVAAHG
NSLRALIMTLEKLSPEGIMKRELNTGAPIVYKLAADSTVAEKRDLVA

Sequences:

>Translated_207_residues
MSDRILVLVRHGQSEWNLKNLFTGWRDPDLTEQGVSEAKRAGALLKAEGLKFDVAFTSDLTRAQKTLGLILGEMGQEGVP
TTRNVALNERDYGDLAGLNKDDARAKWGDDQVHIWRRSYDIAPPGGESLRDTVARTLPYYVQEILPCVLRGQTTLVAAHG
NSLRALIMTLEKLSPEGIMKRELNTGAPIVYKLAADSTVAEKRDLVA
>Mature_206_residues
SDRILVLVRHGQSEWNLKNLFTGWRDPDLTEQGVSEAKRAGALLKAEGLKFDVAFTSDLTRAQKTLGLILGEMGQEGVPT
TRNVALNERDYGDLAGLNKDDARAKWGDDQVHIWRRSYDIAPPGGESLRDTVARTLPYYVQEILPCVLRGQTTLVAAHGN
SLRALIMTLEKLSPEGIMKRELNTGAPIVYKLAADSTVAEKRDLVA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI4505753, Length=220, Percent_Identity=45.9090909090909, Blast_Score=187, Evalue=6e-48,
Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=44.0909090909091, Blast_Score=184, Evalue=4e-47,
Organism=Homo sapiens, GI71274132, Length=220, Percent_Identity=43.1818181818182, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI4502445, Length=222, Percent_Identity=41.4414414414414, Blast_Score=170, Evalue=8e-43,
Organism=Homo sapiens, GI40353764, Length=222, Percent_Identity=41.4414414414414, Blast_Score=170, Evalue=8e-43,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=44.2424242424242, Blast_Score=130, Evalue=7e-31,
Organism=Escherichia coli, GI1786970, Length=213, Percent_Identity=45.5399061032864, Blast_Score=184, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322697, Length=213, Percent_Identity=41.7840375586854, Blast_Score=157, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=26.0377358490566, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320183, Length=269, Percent_Identity=26.7657992565056, Blast_Score=88, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6324857, Length=186, Percent_Identity=29.5698924731183, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI85725270, Length=216, Percent_Identity=45.8333333333333, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI85725272, Length=216, Percent_Identity=45.8333333333333, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24650981, Length=216, Percent_Identity=45.8333333333333, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24646216, Length=216, Percent_Identity=43.9814814814815, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=34.5622119815668, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=34.5622119815668, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=34.5622119815668, Blast_Score=123, Evalue=8e-29,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_XANP2 (A7IC75)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001415275.1
- ProteinModelPortal:   A7IC75
- SMR:   A7IC75
- STRING:   A7IC75
- GeneID:   5421656
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_0360
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK01295
- BioCyc:   XAUT78245:XAUT_0360-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 22842; Mature: 22711

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 11-11 ACT_SITE 159-159

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRILVLVRHGQSEWNLKNLFTGWRDPDLTEQGVSEAKRAGALLKAEGLKFDVAFTSDL
CCCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEEECHHH
TRAQKTLGLILGEMGQEGVPTTRNVALNERDYGDLAGLNKDDARAKWGDDQVHIWRRSYD
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCCEEEEEEEECC
IAPPGGESLRDTVARTLPYYVQEILPCVLRGQTTLVAAHGNSLRALIMTLEKLSPEGIMK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHHH
RELNTGAPIVYKLAADSTVAEKRDLVA
HHCCCCCCEEEEECCCCHHHHHHCCCC
>Mature Secondary Structure 
SDRILVLVRHGQSEWNLKNLFTGWRDPDLTEQGVSEAKRAGALLKAEGLKFDVAFTSDL
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEEECHHH
TRAQKTLGLILGEMGQEGVPTTRNVALNERDYGDLAGLNKDDARAKWGDDQVHIWRRSYD
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCCEEEEEEEECC
IAPPGGESLRDTVARTLPYYVQEILPCVLRGQTTLVAAHGNSLRALIMTLEKLSPEGIMK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHHH
RELNTGAPIVYKLAADSTVAEKRDLVA
HHCCCCCCEEEEECCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA