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The map label for this gene is ftsA [H]

Identifier: 154244284

GI number: 154244284

Start: 337458

End: 338783

Strand: Direct

Name: ftsA [H]

Synonym: Xaut_0327

Alternate gene names: 154244284

Gene position: 337458-338783 (Clockwise)

Preceding gene: 154244283

Following gene: 154244285

Centisome position: 6.36

GC content: 69.91

Gene sequence:

>1326_bases
ATGAGGCACCGGCTCGCCCAGGGCTTCGCGCCGAAGATGCGCCCGATGCCGCCGAAAAAGAGCGGCATCGTCGGTGTGCT
CGACATCGGAACCAGCAAGGTGGTGTGCGCCATCGCACGGCTGAAGCCGCGCGGCGCATCGGATGTGCTCACGCGGCGCA
CCCACGCCATCGACGTGCTCGGCATCGGCCACACCCGCGCCCATGGCATCAAGGGTGGCGCGATCGTGGACATGGCCAAG
GCGGAACTCGCCATCCGCCAGGCGGTGGACATGGCCGAGCGCGCCTCGGGGGTGCAGATCGCCTCCGTGGTGGTGGGCGT
CTCCGGCGGGCGCCTTGCCTCCCAGCATTATGAGGCCGCCGTGCGCCTCACCGCTCCTGCTGTCGAGGAGTTCGACATCC
GCCGCGTGCTTGAGGCCGCCTCCACCTACGGCGTGGGCGACGGGCAGGCGGTGATGCACGCCCTGCCGGTGGGCTATTCG
CTGGACGGGCGGCGCGGCATCGGCGAACCGTGCGGCATGCTAGGGCGCCAGCTCGGCGCCGACATGCATGTCATCACCGC
CGATCTCACGGCGCTGAAGAATCTCGTGCTGTGCGTGGAGCGCTGCCATCTCTCCATCGAGGCCATGGTGGCGGCGCCCT
ATGCGGCGGCACTGTCCTCGCTCACCGACGACGAGATGGAGCTGGGCGTCACCCTCATCGACATGGGGGCCGGCACCACC
ACCTTCTCCATCGTCGCCGGCGGCCACTGCCTCTATGTGGACGGCGTGGCCCTGGGCGGCCAGCACATCACCAACGACGT
GGCCCGCGGCCTGCCGGCGCGCCTTGCCGACGCCGAGCGCATGAAGGCCCTGCACGGCGCCGTGGTGGCAGTCTCCTCCG
ACGACCACGACATGCTCACCGTGCCGCCCTTGTCGGGTGATTCGCGCGATCAGCCGCACATGGTGCCGAAATCGCGCCTC
GTCACCATCGTCCGTCCCCGGGCGGAAGAAATTGTCGAACTGGTGCGCGATCGCCTGAAGGCCTCCGGACACGCCGGCGA
CGCCGGCCGACGCATCGTGCTCACCGGGGGCGCGGCGCAGCTCCAGGGCCTGCCGGACCTCGTGGCGCGGCTCATCGGGC
CGCAGGTGCGCATCGGCCGCCCGCTAGGCGTTTCCAGGCTTCCCGAGGCGGCGCGCGGCGCTGCATTCGCGGTGACGGCA
GGCCTTCTTGTTTACCCTCAGGTGGCAGGGTTGGAGCACTTCGAGCCCCGCCGGAGGCAGGCGGTGGTGGGCGAAAGCCC
GAATTATTTCGGCCGCGTGGGACGCTGGCTGAAGGACAGCTTTTAG

Upstream 100 bases:

>100_bases
GCCTGCCGGACCGCGTCGTGGTCCGGCTTTCGGATGCCGCTGCCGACGCCCGTGCGCAGATGTTGAAGGCGCGGGCCAAG
GCTAAAAAGGGAGGCCCAGC

Downstream 100 bases:

>100_bases
ACATGGTTAACGAAGCCTGGGCTAACAAAGTGGTCAGACAGGATTCGTGAGAGGCGGACAGGCCGATCGGGTTCGACGGA
GCAAAAGCATGACGATCAAT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MRHRLAQGFAPKMRPMPPKKSGIVGVLDIGTSKVVCAIARLKPRGASDVLTRRTHAIDVLGIGHTRAHGIKGGAIVDMAK
AELAIRQAVDMAERASGVQIASVVVGVSGGRLASQHYEAAVRLTAPAVEEFDIRRVLEAASTYGVGDGQAVMHALPVGYS
LDGRRGIGEPCGMLGRQLGADMHVITADLTALKNLVLCVERCHLSIEAMVAAPYAAALSSLTDDEMELGVTLIDMGAGTT
TFSIVAGGHCLYVDGVALGGQHITNDVARGLPARLADAERMKALHGAVVAVSSDDHDMLTVPPLSGDSRDQPHMVPKSRL
VTIVRPRAEEIVELVRDRLKASGHAGDAGRRIVLTGGAAQLQGLPDLVARLIGPQVRIGRPLGVSRLPEAARGAAFAVTA
GLLVYPQVAGLEHFEPRRRQAVVGESPNYFGRVGRWLKDSF

Sequences:

>Translated_441_residues
MRHRLAQGFAPKMRPMPPKKSGIVGVLDIGTSKVVCAIARLKPRGASDVLTRRTHAIDVLGIGHTRAHGIKGGAIVDMAK
AELAIRQAVDMAERASGVQIASVVVGVSGGRLASQHYEAAVRLTAPAVEEFDIRRVLEAASTYGVGDGQAVMHALPVGYS
LDGRRGIGEPCGMLGRQLGADMHVITADLTALKNLVLCVERCHLSIEAMVAAPYAAALSSLTDDEMELGVTLIDMGAGTT
TFSIVAGGHCLYVDGVALGGQHITNDVARGLPARLADAERMKALHGAVVAVSSDDHDMLTVPPLSGDSRDQPHMVPKSRL
VTIVRPRAEEIVELVRDRLKASGHAGDAGRRIVLTGGAAQLQGLPDLVARLIGPQVRIGRPLGVSRLPEAARGAAFAVTA
GLLVYPQVAGLEHFEPRRRQAVVGESPNYFGRVGRWLKDSF
>Mature_441_residues
MRHRLAQGFAPKMRPMPPKKSGIVGVLDIGTSKVVCAIARLKPRGASDVLTRRTHAIDVLGIGHTRAHGIKGGAIVDMAK
AELAIRQAVDMAERASGVQIASVVVGVSGGRLASQHYEAAVRLTAPAVEEFDIRRVLEAASTYGVGDGQAVMHALPVGYS
LDGRRGIGEPCGMLGRQLGADMHVITADLTALKNLVLCVERCHLSIEAMVAAPYAAALSSLTDDEMELGVTLIDMGAGTT
TFSIVAGGHCLYVDGVALGGQHITNDVARGLPARLADAERMKALHGAVVAVSSDDHDMLTVPPLSGDSRDQPHMVPKSRL
VTIVRPRAEEIVELVRDRLKASGHAGDAGRRIVLTGGAAQLQGLPDLVARLIGPQVRIGRPLGVSRLPEAARGAAFAVTA
GLLVYPQVAGLEHFEPRRRQAVVGESPNYFGRVGRWLKDSF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=422, Percent_Identity=29.3838862559242, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46504; Mature: 46504

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHRLAQGFAPKMRPMPPKKSGIVGVLDIGTSKVVCAIARLKPRGASDVLTRRTHAIDVL
CCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHEEEEE
GIGHTRAHGIKGGAIVDMAKAELAIRQAVDMAERASGVQIASVVVGVSGGRLASQHYEAA
ECCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHEE
VRLTAPAVEEFDIRRVLEAASTYGVGDGQAVMHALPVGYSLDGRRGIGEPCGMLGRQLGA
EEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
DMHVITADLTALKNLVLCVERCHLSIEAMVAAPYAAALSSLTDDEMELGVTLIDMGAGTT
CEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCE
TFSIVAGGHCLYVDGVALGGQHITNDVARGLPARLADAERMKALHGAVVAVSSDDHDMLT
EEEEEECCEEEEEECEEECCHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEE
VPPLSGDSRDQPHMVPKSRLVTIVRPRAEEIVELVRDRLKASGHAGDAGRRIVLTGGAAQ
ECCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
LQGLPDLVARLIGPQVRIGRPLGVSRLPEAARGAAFAVTAGLLVYPQVAGLEHFEPRRRQ
HCCCHHHHHHHCCCCEEECCCCCHHHCCHHHCCCCHHHHHHHHCCCHHCCCCCCCCHHHH
AVVGESPNYFGRVGRWLKDSF
EECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRHRLAQGFAPKMRPMPPKKSGIVGVLDIGTSKVVCAIARLKPRGASDVLTRRTHAIDVL
CCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHEEEEE
GIGHTRAHGIKGGAIVDMAKAELAIRQAVDMAERASGVQIASVVVGVSGGRLASQHYEAA
ECCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHEE
VRLTAPAVEEFDIRRVLEAASTYGVGDGQAVMHALPVGYSLDGRRGIGEPCGMLGRQLGA
EEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
DMHVITADLTALKNLVLCVERCHLSIEAMVAAPYAAALSSLTDDEMELGVTLIDMGAGTT
CEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCE
TFSIVAGGHCLYVDGVALGGQHITNDVARGLPARLADAERMKALHGAVVAVSSDDHDMLT
EEEEEECCEEEEEECEEECCHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEE
VPPLSGDSRDQPHMVPKSRLVTIVRPRAEEIVELVRDRLKASGHAGDAGRRIVLTGGAAQ
ECCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
LQGLPDLVARLIGPQVRIGRPLGVSRLPEAARGAAFAVTAGLLVYPQVAGLEHFEPRRRQ
HCCCHHHHHHHCCCCEEECCCCCHHHCCHHHCCCCHHHHHHHHCCCHHCCCCCCCCHHHH
AVVGESPNYFGRVGRWLKDSF
EECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]