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The map label for this gene is regB [H]

Identifier: 154244262

GI number: 154244262

Start: 313013

End: 314347

Strand: Direct

Name: regB [H]

Synonym: Xaut_0305

Alternate gene names: 154244262

Gene position: 313013-314347 (Clockwise)

Preceding gene: 154244259

Following gene: 154244263

Centisome position: 5.9

GC content: 69.14

Gene sequence:

>1335_bases
ATGAGCACCGCCTTCGTCACGCCGCCGCACGGCCGCTCCTTCGGGCTGCGCCTCGACACACTGATTCGCCTGCGCTGGCT
GGCGGTGTCCGGACAGATCCTGGCCCTTGTGGTGGTGAACCTCGGGCTCGGCTTTCCGCTGCCGCTGACCCCGTGCCTCG
CCGTCGTGGGCCTGTCGGCACTGGTGAACGTGCTGCTGCGGGTGAAATATCCGGTGGCCCGCCGGCTCGGGGACGCCGCC
GCAGGGCCGCTGCTGGCCTACGACGTGCTCCAGCTCACCGCTTTGCTCTATCTGACGGGCGGACTAAAGAACCCGTTCGT
ACTGCTGTACCTTGCCCCGGTCATGATCTCCTCCACCGCCCTGTCGTGGAGCACCACGGTGCTCCTGGGGGTGCTCGCGG
TAACCTGCGCCGGGACCGTGGGCCTGTGGGCGCGGCCGCTGCCGTGGGCGGGCGGCAACCTGCCGGTGCTGCCGGACCTT
TATCTCGCCGGCATCTGGGTGTCCCTGTCGGTGGCGGTGGGCTTCATCGGCCTGCACGCCTGGCGAGTGGCCGAGGAGGC
GCGGGAGCTGGCCGACGCGCTCGCCGCCACCGAGCTGGTGCTGGCGCGCGAGCAGCACCTGTCCGCCATCGACGGCCTTG
CCGCCGCCGCCGCCCACGAGCTGGGCACGCCGCTTTCCACCATCGCCCTGGTGGTGAAGGAGATGCAGCGCGCCATGACC
GCGAATGATCCCCTCGCGGAGGACGTGGCGCTGCTGCGCGATCAGGCCAACCGCTGCCGCGACATCCTGCAGAAGCTCAC
CTCCTTGAGCTCGGGCGACGCGCCGTTCGACCGCATGCCGCTGGCGCATCTGCTGGAGGAGGTGGTGGAGCCGCACCGCA
ATTTCGGCATCGCCATCAACGTCCAGGTCAAGGACGATCCGGACGCCCCGGTGATCGCCCGCAATCCCGGCCTGCTCTAC
GGCCTGGGCAACCTGGTGGAGAATGCGGTGGATTTCGCCGCCACGCGGGTGGATATCAGCGCCCAGTGGAGTTTCGCCGG
CCTCGACATCGTGGTGGCGGACGACGGGCCGGGCTTTTCGCCGGAGGTGAGCGGGCGCATCGGCCAGCCCTACGTGACAT
CCCGGGCCCGCGACCGCTTGGAAGAGGACGGCGAAAGCGGGCTGGGTCTCGGCTTCTTCATTGCCAAGACCCTGCTGGAG
CGGACCGGGGCGACCCTGAGCTTCCAGAACCGCTTCCCGCCCGAGACCGGCGCCGTCATCCGCATGCATTGGCCGCGCAA
GGCGCTGGCCATAGAGACGGATGAATACGCGACAAAGGGACGCGGATCAGATTAA

Upstream 100 bases:

>100_bases
TGGTATCTGGGCCACTATTCCCTTACGTCACTTTGGCGGGCGGGCGGGTTCCATGCCGCGCGGACTGCCTTCAAGCCGCT
GATCGGAAAGGCGCTCTCCC

Downstream 100 bases:

>100_bases
TCTACCGGGCAGGCGGCGTAGAAAGCCGCAGCCAGTTCTGTTCGTAACCGGCCCTGCCGGAACTGGATTTGAGGAAGACG
TTATGAATGAGACGACGCCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSTAFVTPPHGRSFGLRLDTLIRLRWLAVSGQILALVVVNLGLGFPLPLTPCLAVVGLSALVNVLLRVKYPVARRLGDAA
AGPLLAYDVLQLTALLYLTGGLKNPFVLLYLAPVMISSTALSWSTTVLLGVLAVTCAGTVGLWARPLPWAGGNLPVLPDL
YLAGIWVSLSVAVGFIGLHAWRVAEEARELADALAATELVLAREQHLSAIDGLAAAAAHELGTPLSTIALVVKEMQRAMT
ANDPLAEDVALLRDQANRCRDILQKLTSLSSGDAPFDRMPLAHLLEEVVEPHRNFGIAINVQVKDDPDAPVIARNPGLLY
GLGNLVENAVDFAATRVDISAQWSFAGLDIVVADDGPGFSPEVSGRIGQPYVTSRARDRLEEDGESGLGLGFFIAKTLLE
RTGATLSFQNRFPPETGAVIRMHWPRKALAIETDEYATKGRGSD

Sequences:

>Translated_444_residues
MSTAFVTPPHGRSFGLRLDTLIRLRWLAVSGQILALVVVNLGLGFPLPLTPCLAVVGLSALVNVLLRVKYPVARRLGDAA
AGPLLAYDVLQLTALLYLTGGLKNPFVLLYLAPVMISSTALSWSTTVLLGVLAVTCAGTVGLWARPLPWAGGNLPVLPDL
YLAGIWVSLSVAVGFIGLHAWRVAEEARELADALAATELVLAREQHLSAIDGLAAAAAHELGTPLSTIALVVKEMQRAMT
ANDPLAEDVALLRDQANRCRDILQKLTSLSSGDAPFDRMPLAHLLEEVVEPHRNFGIAINVQVKDDPDAPVIARNPGLLY
GLGNLVENAVDFAATRVDISAQWSFAGLDIVVADDGPGFSPEVSGRIGQPYVTSRARDRLEEDGESGLGLGFFIAKTLLE
RTGATLSFQNRFPPETGAVIRMHWPRKALAIETDEYATKGRGSD
>Mature_443_residues
STAFVTPPHGRSFGLRLDTLIRLRWLAVSGQILALVVVNLGLGFPLPLTPCLAVVGLSALVNVLLRVKYPVARRLGDAAA
GPLLAYDVLQLTALLYLTGGLKNPFVLLYLAPVMISSTALSWSTTVLLGVLAVTCAGTVGLWARPLPWAGGNLPVLPDLY
LAGIWVSLSVAVGFIGLHAWRVAEEARELADALAATELVLAREQHLSAIDGLAAAAAHELGTPLSTIALVVKEMQRAMTA
NDPLAEDVALLRDQANRCRDILQKLTSLSSGDAPFDRMPLAHLLEEVVEPHRNFGIAINVQVKDDPDAPVIARNPGLLYG
LGNLVENAVDFAATRVDISAQWSFAGLDIVVADDGPGFSPEVSGRIGQPYVTSRARDRLEEDGESGLGLGFFIAKTLLER
TGATLSFQNRFPPETGAVIRMHWPRKALAIETDEYATKGRGSD

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47405; Mature: 47274

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAFVTPPHGRSFGLRLDTLIRLRWLAVSGQILALVVVNLGLGFPLPLTPCLAVVGLSA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVNVLLRVKYPVARRLGDAAAGPLLAYDVLQLTALLYLTGGLKNPFVLLYLAPVMISSTA
HHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
LSWSTTVLLGVLAVTCAGTVGLWARPLPWAGGNLPVLPDLYLAGIWVSLSVAVGFIGLHA
HHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WRVAEEARELADALAATELVLAREQHLSAIDGLAAAAAHELGTPLSTIALVVKEMQRAMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ANDPLAEDVALLRDQANRCRDILQKLTSLSSGDAPFDRMPLAHLLEEVVEPHRNFGIAIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
VQVKDDPDAPVIARNPGLLYGLGNLVENAVDFAATRVDISAQWSFAGLDIVVADDGPGFS
EEECCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHEEEEEEEEEEECEEEEEECCCCCCC
PEVSGRIGQPYVTSRARDRLEEDGESGLGLGFFIAKTLLERTGATLSFQNRFPPETGAVI
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
RMHWPRKALAIETDEYATKGRGSD
EEECCCCEEEEECHHHHCCCCCCC
>Mature Secondary Structure 
STAFVTPPHGRSFGLRLDTLIRLRWLAVSGQILALVVVNLGLGFPLPLTPCLAVVGLSA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVNVLLRVKYPVARRLGDAAAGPLLAYDVLQLTALLYLTGGLKNPFVLLYLAPVMISSTA
HHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHH
LSWSTTVLLGVLAVTCAGTVGLWARPLPWAGGNLPVLPDLYLAGIWVSLSVAVGFIGLHA
HHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WRVAEEARELADALAATELVLAREQHLSAIDGLAAAAAHELGTPLSTIALVVKEMQRAMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ANDPLAEDVALLRDQANRCRDILQKLTSLSSGDAPFDRMPLAHLLEEVVEPHRNFGIAIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
VQVKDDPDAPVIARNPGLLYGLGNLVENAVDFAATRVDISAQWSFAGLDIVVADDGPGFS
EEECCCCCCCEEECCCCCEEEHHHHHHHHHHHHHHEEEEEEEEEEECEEEEEECCCCCCC
PEVSGRIGQPYVTSRARDRLEEDGESGLGLGFFIAKTLLERTGATLSFQNRFPPETGAVI
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
RMHWPRKALAIETDEYATKGRGSD
EEECCCCEEEEECHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]