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The map label for this gene is cph2 [H]

Identifier: 154244236

GI number: 154244236

Start: 281048

End: 282712

Strand: Direct

Name: cph2 [H]

Synonym: Xaut_0279

Alternate gene names: 154244236

Gene position: 281048-282712 (Clockwise)

Preceding gene: 154244234

Following gene: 154244241

Centisome position: 5.29

GC content: 69.31

Gene sequence:

>1665_bases
ATGGTCGAGCGTAGCGGCGAAGAGGCACCTGTCGCTTCGAGACGGCTTTCCAGCCTGCGCCTGCGCATTCTCTTTCTCAT
TTGCCTCGTTGCCGTGCCCCTCTCCGTGGAGCGCCTCATGGCCCTCGTCGCGGATCGCCGGGACCAGATCCAGTCCCTCG
AGGATGACGTGCGCGACTTGGTCCGCCGCGCCACGCTGGCCCAGCTCGAAGGGCTGACGCGGGCCCGCACCGTGCTCGAC
GTGGTGTCGCGGCAGGCGGAGGACCTGCTGGAAGATCCGGCGGCCTGCATCCCTTTCGTGACCCGGCTCGCCGACGAGGT
GGCCGGCATCCAGGGCGTCTTCATCGCCACCCCGGACGGCGACGTGAAATGCGCCCACGCGCCGCTGGCCATGGGCGTCA
ACATCGCGGATCGGCCGTTCTTCCAAGAGGCCCTCGCCGCCGAGGACATGCTCATGACCGAGCTGTCATTTTCACCGGTC
AGCGGGCTCAACTCCGTCTTCATGCTGCGCGCCGAGCGCGCGCCGGGGGGCAAGCCGCTGGCGGTGGCCGGCATCATCCT
CGACCTGCAGTGGCTCTCGCGGATCGCCGCCGGCAGCGCGGTGGAATCGGGTGCGATCGTGGATGTGGTGGGCGAGGGCG
GGACGGTGCTGGTGCGCTATCCGACTTTGCCCGAGATCGTGGAGCACCGCTTTCCGGACCATCCGCTGACGCGCAAGATC
ATGGCCGCGAAGGAAGGCGTCGTCACCACTATCGGCTATGACGGGAAGGAACGGATCTTCGCCTTCAACCGCTTCGAGGG
GCTGAATCTGCGCGTGGTGGTGGGCATGGATACCGCCAAGGTCCTTACGCCCATCGACCGCAAGATCCAGACCACGGCGT
TCGTGCATTTTGCGGCGCTGGCCTGCTTCCTGCTGGTGTCGTGGTTCGCGGCCGAGCGCATCATCATCACGCCCATCGCT
CGGCTGACGCGCTCCGTCGCCGCCGTCGGCCGGGGCGAGGCCGACCATGTGAAGGACAACGACGTCACCGAGTTCGCCCC
GCTGGTGCGGGCCTTCAACGAGATGGCCCGCCGCCTGTCCCAGCGCAACAGCGAGCTGCGCACCATGAACGGGCGGCTCG
CCTCCCTCGCCCGCACCGACGGGCTCACCGGCCTCGCCAACCGCCGCACCTTCGACGTGCAATTCTCCCAGGACTGGGTG
CGCGCCCGCGGCGATGGCGCGCCGCTGACCCTGGTGATGCTGGATGTGGACTACTTCAAGGCGTTCAACGATGCGCGCGG
CCACCTGTCTGGCGACGAGGCCCTGCGCGGGGTTGCGCGCATGCTGTCGGCGGCGGCGGCGGGGACGAAGCATCTGGTCG
CCCGCTACGGGGGCGAGGAATTCATCGTGCTGATGTCCGGGGCGGACCTGGCCGAGGGCCTGGCGTTCGCGGAGGATGTC
CGCGGTCTGCTGGGGGAGGTGGCCATCGCCCATCCAGCCTCGCCCCGCCGTCGCCTGACGGCGAGCTTCGGTGTGGCCAG
CACCATTCCGACGCAGGAGGGCAGCCCGGACACGCTGGTGGCGGCGGCCGATGCCGCGCTCTACGAGGCCAAGCGCTCCG
GCCGGGACCGGGTGGTCGCCCACGCCGACCTGTACGCCAGCGGGGCGAACGGCACCTTCCGTTAG

Upstream 100 bases:

>100_bases
TCCGGCAGCAGATGGACCGATCTCCCCATCCGATCAAGAAGCGTTTACAACACTCCTGGTGGCACCTTCGAGAAGAAGCC
GGTGGGGAGCGTGACCGAGC

Downstream 100 bases:

>100_bases
GGCATGTCGGGTCCGGCTCAGGCGAGCCGGCGGATGCTGCGCAGCTCCAGCCCGACCGCGGAGATCCGCGCCAGCGCCTC
GGCGAGGGGTTCGCGCGCCA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MVERSGEEAPVASRRLSSLRLRILFLICLVAVPLSVERLMALVADRRDQIQSLEDDVRDLVRRATLAQLEGLTRARTVLD
VVSRQAEDLLEDPAACIPFVTRLADEVAGIQGVFIATPDGDVKCAHAPLAMGVNIADRPFFQEALAAEDMLMTELSFSPV
SGLNSVFMLRAERAPGGKPLAVAGIILDLQWLSRIAAGSAVESGAIVDVVGEGGTVLVRYPTLPEIVEHRFPDHPLTRKI
MAAKEGVVTTIGYDGKERIFAFNRFEGLNLRVVVGMDTAKVLTPIDRKIQTTAFVHFAALACFLLVSWFAAERIIITPIA
RLTRSVAAVGRGEADHVKDNDVTEFAPLVRAFNEMARRLSQRNSELRTMNGRLASLARTDGLTGLANRRTFDVQFSQDWV
RARGDGAPLTLVMLDVDYFKAFNDARGHLSGDEALRGVARMLSAAAAGTKHLVARYGGEEFIVLMSGADLAEGLAFAEDV
RGLLGEVAIAHPASPRRRLTASFGVASTIPTQEGSPDTLVAAADAALYEAKRSGRDRVVAHADLYASGANGTFR

Sequences:

>Translated_554_residues
MVERSGEEAPVASRRLSSLRLRILFLICLVAVPLSVERLMALVADRRDQIQSLEDDVRDLVRRATLAQLEGLTRARTVLD
VVSRQAEDLLEDPAACIPFVTRLADEVAGIQGVFIATPDGDVKCAHAPLAMGVNIADRPFFQEALAAEDMLMTELSFSPV
SGLNSVFMLRAERAPGGKPLAVAGIILDLQWLSRIAAGSAVESGAIVDVVGEGGTVLVRYPTLPEIVEHRFPDHPLTRKI
MAAKEGVVTTIGYDGKERIFAFNRFEGLNLRVVVGMDTAKVLTPIDRKIQTTAFVHFAALACFLLVSWFAAERIIITPIA
RLTRSVAAVGRGEADHVKDNDVTEFAPLVRAFNEMARRLSQRNSELRTMNGRLASLARTDGLTGLANRRTFDVQFSQDWV
RARGDGAPLTLVMLDVDYFKAFNDARGHLSGDEALRGVARMLSAAAAGTKHLVARYGGEEFIVLMSGADLAEGLAFAEDV
RGLLGEVAIAHPASPRRRLTASFGVASTIPTQEGSPDTLVAAADAALYEAKRSGRDRVVAHADLYASGANGTFR
>Mature_554_residues
MVERSGEEAPVASRRLSSLRLRILFLICLVAVPLSVERLMALVADRRDQIQSLEDDVRDLVRRATLAQLEGLTRARTVLD
VVSRQAEDLLEDPAACIPFVTRLADEVAGIQGVFIATPDGDVKCAHAPLAMGVNIADRPFFQEALAAEDMLMTELSFSPV
SGLNSVFMLRAERAPGGKPLAVAGIILDLQWLSRIAAGSAVESGAIVDVVGEGGTVLVRYPTLPEIVEHRFPDHPLTRKI
MAAKEGVVTTIGYDGKERIFAFNRFEGLNLRVVVGMDTAKVLTPIDRKIQTTAFVHFAALACFLLVSWFAAERIIITPIA
RLTRSVAAVGRGEADHVKDNDVTEFAPLVRAFNEMARRLSQRNSELRTMNGRLASLARTDGLTGLANRRTFDVQFSQDWV
RARGDGAPLTLVMLDVDYFKAFNDARGHLSGDEALRGVARMLSAAAAGTKHLVARYGGEEFIVLMSGADLAEGLAFAEDV
RGLLGEVAIAHPASPRRRLTASFGVASTIPTQEGSPDTLVAAADAALYEAKRSGRDRVVAHADLYASGANGTFR

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=35.0282485875706, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=37.888198757764, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=37.4301675977654, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=33.8983050847458, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=35.5828220858896, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=34.5029239766082, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787802, Length=135, Percent_Identity=37.7777777777778, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787056, Length=164, Percent_Identity=34.7560975609756, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=189, Percent_Identity=31.2169312169312, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788956, Length=230, Percent_Identity=28.695652173913, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=177, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 59851; Mature: 59851

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERSGEEAPVASRRLSSLRLRILFLICLVAVPLSVERLMALVADRRDQIQSLEDDVRDL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRRATLAQLEGLTRARTVLDVVSRQAEDLLEDPAACIPFVTRLADEVAGIQGVFIATPDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCC
DVKCAHAPLAMGVNIADRPFFQEALAAEDMLMTELSFSPVSGLNSVFMLRAERAPGGKPL
CCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCE
AVAGIILDLQWLSRIAAGSAVESGAIVDVVGEGGTVLVRYPTLPEIVEHRFPDHPLTRKI
EHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHH
MAAKEGVVTTIGYDGKERIFAFNRFEGLNLRVVVGMDTAKVLTPIDRKIQTTAFVHFAAL
HHHCCCCEEEECCCCCHHEEEEECCCCCEEEEEEECCHHHHHCHHHHHHHHHHHHHHHHH
ACFLLVSWFAAERIIITPIARLTRSVAAVGRGEADHVKDNDVTEFAPLVRAFNEMARRLS
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QRNSELRTMNGRLASLARTDGLTGLANRRTFDVQFSQDWVRARGDGAPLTLVMLDVDYFK
HCCCHHHHHCCHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHCCCCCCEEEEEEEHHHHH
AFNDARGHLSGDEALRGVARMLSAAAAGTKHLVARYGGEEFIVLMSGADLAEGLAFAEDV
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
RGLLGEVAIAHPASPRRRLTASFGVASTIPTQEGSPDTLVAAADAALYEAKRSGRDRVVA
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEE
HADLYASGANGTFR
EEEEEEECCCCCCC
>Mature Secondary Structure
MVERSGEEAPVASRRLSSLRLRILFLICLVAVPLSVERLMALVADRRDQIQSLEDDVRDL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VRRATLAQLEGLTRARTVLDVVSRQAEDLLEDPAACIPFVTRLADEVAGIQGVFIATPDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCC
DVKCAHAPLAMGVNIADRPFFQEALAAEDMLMTELSFSPVSGLNSVFMLRAERAPGGKPL
CCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCE
AVAGIILDLQWLSRIAAGSAVESGAIVDVVGEGGTVLVRYPTLPEIVEHRFPDHPLTRKI
EHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHH
MAAKEGVVTTIGYDGKERIFAFNRFEGLNLRVVVGMDTAKVLTPIDRKIQTTAFVHFAAL
HHHCCCCEEEECCCCCHHEEEEECCCCCEEEEEEECCHHHHHCHHHHHHHHHHHHHHHHH
ACFLLVSWFAAERIIITPIARLTRSVAAVGRGEADHVKDNDVTEFAPLVRAFNEMARRLS
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QRNSELRTMNGRLASLARTDGLTGLANRRTFDVQFSQDWVRARGDGAPLTLVMLDVDYFK
HCCCHHHHHCCHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHCCCCCCEEEEEEEHHHHH
AFNDARGHLSGDEALRGVARMLSAAAAGTKHLVARYGGEEFIVLMSGADLAEGLAFAEDV
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
RGLLGEVAIAHPASPRRRLTASFGVASTIPTQEGSPDTLVAAADAALYEAKRSGRDRVVA
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEE
HADLYASGANGTFR
EEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]