Click here to switch to the map view.

The map label for this gene is modD [H]

Identifier: 154244106

GI number: 154244106

Start: 142434

End: 143276

Strand: Direct

Name: modD [H]

Synonym: Xaut_0148

Alternate gene names: 154244106

Gene position: 142434-143276 (Clockwise)

Preceding gene: 154244105

Following gene: 154244107

Centisome position: 2.68

GC content: 70.94

Gene sequence:

>843_bases
ATGACCTACAAATGGTGGACGCAGGCGAGCGTGGATGCCCTCCTCGCCGAGGACGCGCCCTATGGCGACCTCACCACCGA
ATCCCTTGCCCTCACCGGACGCAAGGCCCGCCTCACCATGGCCATGCGGGCCGACGCCACCTTGTGCGGCGTCGAGCTGG
CGCGGGACCTGTTCCGGACCGCCGGGGCGGAGGCCGATGTGCTCGCCGCCACCGGCGCGCGGGCGCCGGCCGGCGAGACC
ATCCTGATGGCGCAGGGCACGGCCGGCCCCATCTTTCGCGCATGGAAGGTGGCGCAGACGCTGGTGGAATATCTCTCCGG
CATCGCCACGCTTACCGCCGACATTGTGGCGACCGCCCGCGCCGTTTCGCCCGACATCGCGGTGGTGACAACGCGCAAGA
CCTTGCCCGGCGCCAAGGCACAGATGATCGCCGCCATCCGCGCCGGCGGGGCCTTTCCCCACCGGCTCGGATTGTCGGAA
ACGCTCCTGCTGTTTCCCGAGCACCAGGCCTTCCTCACCGACTCCGCCGTCGGCATTGCCGCCCTGCGCCGCGCCGCGCC
GGAGAAGAAGGTGGTGGTGGAGGTGAAGACGCTGGACGAGGTGGACGCGGTGCTGCCAGCCCATCCCGACGTGCTCCAGT
GCGAGAAGATGACCCCCAGCGACATCGCCGAGGTGGCCCGCCGGGTGGCGGCGCGCGCGCCGGAGACGAAAGTCGCGGCC
GCCGGCGGCGTGAACCTCGCCAATGCCGCGACCTACGCCGCCGCGGGCGCCCATGTGCTGGTAACTTCCGCGCCCTATTG
GGCCAGGCCGGCTGACGTGAAGGTGGTGATCTCGCCGGCCTGA

Upstream 100 bases:

>100_bases
GCGGGTTTCCCGGCAAGCGCTTCTTTGTCCCGTAGACCATCCCGCCCGGGCGTTATAAGCCTGCCAGCTGTATCGGATCC
GGCATAGGCGGGGGCGGCGC

Downstream 100 bases:

>100_bases
CCCGCGTTCGGGCAGGTGTCGTTGATGTGCTGGAAACTTGTTTTCCACACCGGCTCCTGCGCCATTGTCCGCTCGAAAAC
GGTTGTTCAGCCAGGCGAAC

Product: modD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTYKWWTQASVDALLAEDAPYGDLTTESLALTGRKARLTMAMRADATLCGVELARDLFRTAGAEADVLAATGARAPAGET
ILMAQGTAGPIFRAWKVAQTLVEYLSGIATLTADIVATARAVSPDIAVVTTRKTLPGAKAQMIAAIRAGGAFPHRLGLSE
TLLLFPEHQAFLTDSAVGIAALRRAAPEKKVVVEVKTLDEVDAVLPAHPDVLQCEKMTPSDIAEVARRVAARAPETKVAA
AGGVNLANAATYAAAGAHVLVTSAPYWARPADVKVVISPA

Sequences:

>Translated_280_residues
MTYKWWTQASVDALLAEDAPYGDLTTESLALTGRKARLTMAMRADATLCGVELARDLFRTAGAEADVLAATGARAPAGET
ILMAQGTAGPIFRAWKVAQTLVEYLSGIATLTADIVATARAVSPDIAVVTTRKTLPGAKAQMIAAIRAGGAFPHRLGLSE
TLLLFPEHQAFLTDSAVGIAALRRAAPEKKVVVEVKTLDEVDAVLPAHPDVLQCEKMTPSDIAEVARRVAARAPETKVAA
AGGVNLANAATYAAAGAHVLVTSAPYWARPADVKVVISPA
>Mature_279_residues
TYKWWTQASVDALLAEDAPYGDLTTESLALTGRKARLTMAMRADATLCGVELARDLFRTAGAEADVLAATGARAPAGETI
LMAQGTAGPIFRAWKVAQTLVEYLSGIATLTADIVATARAVSPDIAVVTTRKTLPGAKAQMIAAIRAGGAFPHRLGLSET
LLLFPEHQAFLTDSAVGIAALRRAAPEKKVVVEVKTLDEVDAVLPAHPDVLQCEKMTPSDIAEVARRVAARAPETKVAAA
GGVNLANAATYAAAGAHVLVTSAPYWARPADVKVVISPA

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321162, Length=276, Percent_Identity=25.7246376811594, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 29176; Mature: 29045

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKWWTQASVDALLAEDAPYGDLTTESLALTGRKARLTMAMRADATLCGVELARDLFRT
CCEEEECCHHHHHHHHCCCCCCCCCCHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGAEADVLAATGARAPAGETILMAQGTAGPIFRAWKVAQTLVEYLSGIATLTADIVATAR
CCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSPDIAVVTTRKTLPGAKAQMIAAIRAGGAFPHRLGLSETLLLFPEHQAFLTDSAVGIA
HCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHCCCCCEEEEECCCHHHHCCCHHHHH
ALRRAAPEKKVVVEVKTLDEVDAVLPAHPDVLQCEKMTPSDIAEVARRVAARAPETKVAA
HHHHCCCCCEEEEEEECHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEE
AGGVNLANAATYAAAGAHVLVTSAPYWARPADVKVVISPA
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TYKWWTQASVDALLAEDAPYGDLTTESLALTGRKARLTMAMRADATLCGVELARDLFRT
CEEEECCHHHHHHHHCCCCCCCCCCHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGAEADVLAATGARAPAGETILMAQGTAGPIFRAWKVAQTLVEYLSGIATLTADIVATAR
CCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSPDIAVVTTRKTLPGAKAQMIAAIRAGGAFPHRLGLSETLLLFPEHQAFLTDSAVGIA
HCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHCCCCCEEEEECCCHHHHCCCHHHHH
ALRRAAPEKKVVVEVKTLDEVDAVLPAHPDVLQCEKMTPSDIAEVARRVAARAPETKVAA
HHHHCCCCCEEEEEEECHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEE
AGGVNLANAATYAAAGAHVLVTSAPYWARPADVKVVISPA
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA